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Breastfeeding and infant feeding الرضاعة

Nursing, its duration and its outcomes for mother and child.

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Qurʾān

القرآن5 shown

Verses named for this subject by hand come first. The rest are found by the subject’s own Arabic and English senses and are shown as lexical matches, not as anchors anyone has confirmed.

Qur'ān 2:233Arabic sense: الرضاع, رضاع, فصال | English sense: suckle, weaning

۞وَٱلۡوَٰلِدَٰتُ يُرۡضِعۡنَ أَوۡلَٰدَهُنَّ حَوۡلَيۡنِ كَامِلَيۡنِۖ لِمَنۡ أَرَادَ أَن يُتِمَّ ٱلرَّضَاعَةَۚ وَعَلَى ٱلۡمَوۡلُودِ لَهُۥ رِزۡقُهُنَّ وَكِسۡوَتُهُنَّ بِٱلۡمَعۡرُوفِۚ لَا تُكَلَّفُ نَفۡسٌ إِلَّا وُسۡعَهَاۚ لَا تُضَآرَّ وَٰلِدَةُۢ بِوَلَدِهَا وَلَا مَوۡلُودࣱ لَّهُۥ بِوَلَدِهِۦۚ وَعَلَى ٱلۡوَارِثِ مِثۡلُ ذَٰلِكَۗ فَإِنۡ أَرَادَا فِصَالًا عَن تَرَاضࣲ مِّنۡهُمَا وَتَشَاوُرࣲ فَلَا جُنَاحَ عَلَيۡهِمَاۗ وَإِنۡ أَرَدتُّمۡ أَن تَسۡتَرۡضِعُوٓاْ أَوۡلَٰدَكُمۡ فَلَا جُنَاحَ عَلَيۡكُمۡ إِذَا سَلَّمۡتُم مَّآ ءَاتَيۡتُم بِٱلۡمَعۡرُوفِۗ وَٱتَّقُواْ ٱللَّهَ وَٱعۡلَمُوٓاْ أَنَّ ٱللَّهَ بِمَا تَعۡمَلُونَ بَصِيرࣱ‏

Mothers suckle their children for two whole years, if they wish to complete the term, and clothing and maintenance must be borne by the father in a fair manner. No one should be burdened with more than they can bear: no mother shall be made to suffer harm on account of her child, nor any father on account of his. The same duty is incumbent on the father’s heir. If, by mutual consent and consultation, the couple wish to wean [the child], they will not be blamed, nor will there be any blame if you wish to engage a wet nurse, provided you pay as agreed in a fair manner. Be mindful of God, knowing that He sees everything you do

Qur'ān 28:7English sense: suckle

وَأَوۡحَيۡنَآ إِلَىٰٓ أُمِّ مُوسَىٰٓ أَنۡ أَرۡضِعِيهِۖ فَإِذَا خِفۡتِ عَلَيۡهِ فَأَلۡقِيهِ فِي ٱلۡيَمِّ وَلَا تَخَافِي وَلَا تَحۡزَنِيٓۖ إِنَّا رَآدُّوهُ إِلَيۡكِ وَجَاعِلُوهُ مِنَ ٱلۡمُرۡسَلِينَ

We inspired Moses’ mother, saying, ‘Suckle him, and then, when you fear for his safety, put him in the river: do not be afraid, and do not grieve, for We shall return him to you and make him a messenger.’

Qur'ān 31:14English sense: weaning

وَوَصَّيۡنَا ٱلۡإِنسَٰنَ بِوَٰلِدَيۡهِ حَمَلَتۡهُ أُمُّهُۥ وَهۡنًا عَلَىٰ وَهۡنࣲ وَفِصَٰلُهُۥ فِي عَامَيۡنِ أَنِ ٱشۡكُرۡ لِي وَلِوَٰلِدَيۡكَ إِلَيَّ ٱلۡمَصِيرُ

We have commanded people to be good to their parents: their mothers carried them, with strain upon strain, and it takes two years to wean them. Give thanks to Me and to your parents- all will return to Me

Qur'ān 46:15English sense: weaning

وَوَصَّيۡنَا ٱلۡإِنسَٰنَ بِوَٰلِدَيۡهِ إِحۡسَٰنًاۖ حَمَلَتۡهُ أُمُّهُۥ كُرۡهࣰ ا وَوَضَعَتۡهُ كُرۡهࣰ اۖ وَحَمۡلُهُۥ وَفِصَٰلُهُۥ ثَلَٰثُونَ شَهۡرًاۚ حَتَّىٰٓ إِذَا بَلَغَ أَشُدَّهُۥ وَبَلَغَ أَرۡبَعِينَ سَنَةࣰ قَالَ رَبِّ أَوۡزِعۡنِيٓ أَنۡ أَشۡكُرَ نِعۡمَتَكَ ٱلَّتِيٓ أَنۡعَمۡتَ عَلَيَّ وَعَلَىٰ وَٰلِدَيَّ وَأَنۡ أَعۡمَلَ صَٰلِحࣰ ا تَرۡضَىٰهُ وَأَصۡلِحۡ لِي فِي ذُرِّيَّتِيٓۖ إِنِّي تُبۡتُ إِلَيۡكَ وَإِنِّي مِنَ ٱلۡمُسۡلِمِينَ

We have commanded man to be good to his parents: his mother struggled to carry him and struggled to give birth to him- his bearing and weaning took a full thirty months. When he has grown to manhood and reached the age of forty he [may] say, ‘Lord, help me to be truly grateful for Your favours to me and to my parents; help me to do good work that pleases You; make my offspring good. I turn to You; I am one of those who devote themselves to You.’

Qur'ān 65:6English sense: suckle

أَسۡكِنُوهُنَّ مِنۡ حَيۡثُ سَكَنتُم مِّن وُجۡدِكُمۡ وَلَا تُضَآرُّوهُنَّ لِتُضَيِّقُواْ عَلَيۡهِنَّۚ وَإِن كُنَّ أُوْلَٰتِ حَمۡلࣲ فَأَنفِقُواْ عَلَيۡهِنَّ حَتَّىٰ يَضَعۡنَ حَمۡلَهُنَّۚ فَإِنۡ أَرۡضَعۡنَ لَكُمۡ فَـَٔاتُوهُنَّ أُجُورَهُنَّ وَأۡتَمِرُواْ بَيۡنَكُم بِمَعۡرُوفࣲۖ وَإِن تَعَاسَرۡتُمۡ فَسَتُرۡضِعُ لَهُۥٓ أُخۡرَىٰ

House the wives you are divorcing according to your means, wherever you house yourselves, and do not harass them so as to make their lives difficult. If they are pregnant, maintain them until they are delivered of their burdens; if they suckle your infants, pay them for it. Consult together in a good way- if you make difficulties for one another, another woman may suckle the child for the father––

Tafsīr

التفسير6 shown

Commentary on the verses above, at most two editions per verse.

en-asbab-al-nuzul-by-al-wahidi on 2:233en-asbab-al-nuzul-by-al-wahidicommentary on an ayah this subject surfaced

Mothers shall suckle their children two whole years-for those who desire to complete the suckling. Great is that Lord who is unique in loving kindness and without peer in caressing servants. He be- stows in testing, He is loyal to assurances. If we call Him, He hears, and if we do not, He knows. He is generous, loving, love-showing, and love-increasing; gentle, defect-hiding, excuse-hearing, a good God. His bounty is beyond all bounty, His generosity beyond all generosity, His mercy greater than all mercies, His love not like other loves. The example given of utmost mercy is the mercy of mothers, but God's mercy toward His servants is more than that, and His love is not like their love. Do you not see that He commands mothers to give milk to their children for two complete years, He urges them to nurture them, and He counsels them to take care of them? He does not confine Himself to the

en-al-jalalayn on 2:233en-al-jalalayncommentary on an ayah this subject surfaced

Mothers shall suckle their children for two full years kāmilayn ‘two full ones’ is an adjective for emphasis; this is for such as desire to fulfil the suckling and this is the maximum length of time. It is for the father to provide food for them the mothers and clothe them during the suckling if they be divorced honourably to the best of his ability. No soul is charged save to its capacity its ability; a mother shall not be harmed by her child that is on account of the child by being forced to suckle it if she does not want to; neither should a father be harmed by his child that is on account of it by being charged with more than he is able to bear. The mention of both parents here in relation to the child is intended to show sympathy for both. The heir the one inheriting from his father that is the young man who is the trustee of his father’s property has a similar duty to that of the f

en-asbab-al-nuzul-by-al-wahidi on 46:15en-asbab-al-nuzul-by-al-wahidicommentary on an ayah this subject surfaced

(�till, when he attaineth full strength and reacheth forty years�) [46:15]. 'Ata' reported that Ibn 'Abbas said: �This verse was revealed about Abu Bakr al-Siddiq, may Allah be well pleased with him. He had travelled with the Messenger of Allah, Allah bless him and give him peace - when he was eighteen years old and the Messenger of Allah, Allah bless him and give him peace, was twenty - to Syria for trade. When they reached a place where there was a lotus tree, the Messenger of Allah, Allah bless him and give him peace, sat under the shade of this tree while Abu Bakr went to a monk nearby to ask him about religion. The monk then asked Abu Bakr: 'Who is that man under the shade of the lotus?' Abu Bakr said: 'He is Muhammad ibn 'Abd Allah ibn 'Abd al-Muttalib'. The monk said: 'By Allah, he is a Prophet. No one sat under the shade of this tree after Jesus, son of Mary, except Muhammad the

en-al-jalalayn on 28:7en-al-jalalayncommentary on an ayah this subject surfaced

And We revealed by inspiration or in a dream to the mother of Moses — who was the said new-born; his sister was the only other person aware of his birth — ‘Suckle him then when you fear for him cast him into the waters namely the Nile and do not fear that he should drown or grieve for being separated from him for We will restore him to you and make him one of the messengers’. She suckled him for three months during which he never cried. She then began to fear for him and so she placed him in a basket coated with pitch and made as a cradle for him on the inside. She then closed it and cast it into the waters of the Nile at night.

en-al-jalalayn on 31:14en-al-jalalayncommentary on an ayah this subject surfaced

And We have enjoined man concerning his parents We commanded him to be dutiful towards them — his mother bears him and weakens in weakness after weakness that is to say she is weakened by the pregnancy the pains of labour and the delivery; and his weaning is in two years and We said to him to man ‘Give thanks to Me and to your parents. To Me is the journey’s end the return.

en-tafisr-ibn-kathir on 28:7en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

And We inspired the mother of Musa: "Suckle him (Musa), but when you fear for him, then cast him into the river and fear not, nor grieve. Verily, We shall bring him back to you, and shall make him one of the Messengers. (7)Then the household of Fir'awn picked him up, that he might become for them an enemy and a (cause of) grief. Verily, Fir'awn, Haman and their armies were sinners (8)And the wife of Fir'awn said: "A comfort of the eye for me and for you. Kill him not, perhaps he may be of benefit to us, or we may adopt him as a son." And they perceived not (9) How Musa's Mother was inspired and shown what to do It was mentioned that when Fir'awn killed so many of the males of the Children of Israel, the Copts were scared that the Children of Israel would die out, and they themselves would have to do the heavy labor that the Children of Israel used to do. So they said to Fir'awn, "If th

Ḥadīth

الحديث4 shown

Sound narrations only, and never matched by text. A narration appears here because a compiler filed it under a chapter this subject maps to, or because someone read it and anchored it. Each row says which.

Jami' at-Tirmidhi 1146The Book On Sucklingfiled here by the compiler

حَدَّثَنَا أَحْمَدُ بْنُ مَنِيعٍ، حَدَّثَنَا إِسْمَاعِيلُ بْنُ إِبْرَاهِيمَ، حَدَّثَنَا عَلِيُّ بْنُ زَيْدٍ، عَنْ سَعِيدِ بْنِ الْمُسَيَّبِ، عَنْ عَلِيِّ بْنِ أَبِي طَالِبٍ، قَالَ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏ "‏ إِنَّ اللَّهَ حَرَّمَ مِنَ الرَّضَاعِ مَا حَرَّمَ مِنَ النَّسَبِ ‏"‏ ‏.‏ قَالَ وَفِي الْبَابِ عَنْ عَائِشَةَ وَابْنِ عَبَّاسٍ وَأُمِّ حَبِيبَةَ ‏.‏ قَالَ أَبُو عِيسَى حَدِيثُ عَلِيٍّ حَسَنٌ صَحِيحٌ ‏.‏

Ali (bin Abi Talib) narrated that The Messenger of Allah said:“Indeed Allah has made unlawful through suckling whatever He made unlawful through lineage.”

Jami' at-Tirmidhi 1147The Book On Sucklingfiled here by the compiler

حَدَّثَنَا بُنْدَارٌ، حَدَّثَنَا يَحْيَى بْنُ سَعِيدٍ الْقَطَّانُ، حَدَّثَنَا مَالِكٌ، ح وَحَدَّثَنَا إِسْحَاقُ بْنُ مُوسَى الأَنْصَارِيُّ، قَالَ حَدَّثَنَا مَعْنٌ، قَالَ حَدَّثَنَا مَالِكٌ، عَنْ عَبْدِ اللَّهِ بْنِ دِينَارٍ، عَنْ سُلَيْمَانَ بْنِ يَسَارٍ، عَنْ عُرْوَةَ بْنِ الزُّبَيْرِ، عَنْ عَائِشَةَ، قَالَتْ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏ "‏ إِنَّ اللَّهَ حَرَّمَ مِنَ الرَّضَاعَةِ مَا حَرَّمَ مِنَ الْوِلاَدَةِ ‏"‏ ‏.‏ قَالَ أَبُو عِيسَى هَذَا حَدِيثٌ حَسَنٌ صَحِيحٌ ‏.‏ وَالْعَمَلُ عَلَى هَذَا عِنْدَ أَهْلِ الْعِلْمِ مِنْ أَصْحَابِ النَّبِيِّ صلى الله عليه وسلم وَغَيْرِهِمْ لاَ نَعْلَمُ بَيْنَهُمْ فِي ذَلِكَ اخْتِلاَفًا ‏.‏

Aishah narrated that the Messenger of Allah said:“Indeed Allah has made unlawful through suckling whatever He made unlawful through birth.”

Sahih Muslim 1444Sucklingfiled here by the compiler

حَدَّثَنَا يَحْيَى بْنُ يَحْيَى، قَالَ قَرَأْتُ عَلَى مَالِكٍ عَنْ عَبْدِ اللَّهِ بْنِ أَبِي بَكْرٍ، عَنْ عَمْرَةَ، أَنَّ عَائِشَةَ، أَخْبَرَتْهَا أَنَّ رَسُولَ اللَّهِ صلى الله عليه وسلم كَانَ عِنْدَهَا وَإِنَّهَا سَمِعَتْ صَوْتَ رَجُلٍ يَسْتَأْذِنُ فِي بَيْتِ حَفْصَةَ ‏.‏ قَالَتْ عَائِشَةُ فَقُلْتُ يَا رَسُولَ اللَّهِ هَذَا رَجُلٌ يَسْتَأْذِنُ فِي بَيْتِكَ ‏.‏ فَقَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏"‏ أُرَاهُ فُلاَنًا ‏"‏ ‏.‏ لِعَمِّ حَفْصَةَ مِنَ الرَّضَاعَةِ ‏.‏ فَقَالَتْ عَائِشَةُ يَا رَسُولَ اللَّهِ لَوْ كَانَ فُلاَنٌ حَيًّا - لِعَمِّهَا مِنَ الرَّضَاعَةِ - دَخَلَ عَلَىَّ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏"‏ نَعَمْ إِنَّ الرَّضَاعَةَ تُحَرِّمُ مَا تُحَرِّمُ الْوِلاَدَةُ ‏"‏ ‏.‏

A'isha (Allah be pleased with her) reported tha Allah's Messenger (ﷺ) was with her and she heard the voice of a person seeking permission to enter the house of Hafsa. 'A'isha (Allah he pleased with her) said:Allah's Messenger, he is the person who seeks permission to enter your house, whereupon Allah's Messenger (ﷺ) said: I think he is so and so (uncle of Hafsa by reason of fosterage). 'A'isha said: Messenger of Allah, if so and so (her uncle by reason of fosterage) were alive, could he enter my house? Allah's Messenger (ﷺ) said: Yes. Fosterage makes unlawful what consanguinity makes unlawful

Sahih Muslim 1445Sucklingfiled here by the compiler

حَدَّثَنَا يَحْيَى بْنُ يَحْيَى، قَالَ قَرَأْتُ عَلَى مَالِكٍ عَنِ ابْنِ شِهَابٍ، عَنْ عُرْوَةَ بْنِ الزُّبَيْرِ، عَنْ عَائِشَةَ، أَنَّهَا أَخْبَرَتْهُ أَنَّ أَفْلَحَ - أَخَا أَبِي الْقُعَيْسِ - جَاءَ يَسْتَأْذِنُ عَلَيْهَا وَهُوَ عَمُّهَا مِنَ الرَّضَاعَةِ بَعْدَ أَنْ أُنْزِلَ الْحِجَابُ قَالَتْ فَأَبَيْتُ أَنْ آذَنَ لَهُ فَلَمَّا جَاءَ رَسُولُ اللَّهِ صلى الله عليه وسلم أَخْبَرْتُهُ بِالَّذِي صَنَعْتُ فَأَمَرَنِي أَنْ آذَنَ لَهُ عَلَىَّ ‏.‏

A'isha (Allah be pleased with her) reported that Aflah, the brother of Abu'l-Qu'ais, who was her uncle by reason of fosterage, came, and asked her permission (to enter the house) after seclusion (Hijab) was instituted. I refused to admit him. When Allah's Messenger (ﷺ) came, I informed him what I had done. He commanded me to grant him permission (as the brother of her foster-father was also her uncle)

Classical works

كتب التراث6 shown

Arabic originals, reached through the subject’s Arabic senses. Interpretive sources, never proof of a ruling.

ihya §3790ihyaArabic sense: الرضاع, رضاع

العاشر أن تكون محرمة بالرضاع ويحرم من الرضاع ما يحرم من النسب من الأصول والفصول كما سبق ولكن المحرم خمس رضعات وما دون ذلك لا يحرم

ihya §4796ihyaArabic sense: الرضاع, رضاع

وهذا غلط لأن بيع الخمور باطل إذ لم يبق للخمر منفعه في الشرع وثمن البيع الباطل حرام وليس هذا من ذلك بل مثال هذا أن يملك الرجل جارية هي أخته من الرضاع فتباع بجارية أجنبية فليس لأحد أن يتورع منه وتشبيه ذلك ببيع الخمر غاية السرف في هذا الطرف

riyad-salihin §1467riyad-salihinArabic sense: الفصال, فصال

1143 عن زيد بن أرقم رضي الله عنه أنه رأى قوما يصلون من الضحى فقال أما لقد علموا أن الصلاة في غير هذه الساعة أفضل إن رسول الله صلى الله عليه وسلم قال صلاة الأوابين حين ترمض الفصال رواه مسلم ترمض بفتح التاء والميم وبالضاد المعجمة يعني شدة الحر والفصال جمع فصيل وهو الصغير من الإبل

riyad-salihin §414riyad-salihinArabic sense: الرضاع, رضاع

325 وعن أسماء بنت أبي بكر الصديق رضي الله عنهما قالت قدمت علي أمي وهي مشركة في عهد رسول الله صلى الله عليه وسلم فاستفتيت رسول الله صلى الله عليه وسلم قلت قدمت علي أمى وهى راغبة أفأصل أمي قال نعم صلي أمك متفق عليه وقولها راغبة أي طامعة عندي تسألني شيئا قيل كانت أمها من النسب وقيل من الرضاعة والصحيح

ihya §4017ihyaArabic sense: الرضاع, رضاع

الخامسة أن تمتنع المرأة لتعززها ومبالغتها في النظافة والتحرز من الطلق والنفاس والرضاع وكان ذلك عادة نساء الخوارج لمبالغتهن في استعمال المياه حتى كن يقضين صلوات أيام الحيض ولا يدخلن الخلاء إلا عراة فهذه بدعة تخالف السنة فهي نية فاسدة واستأذنت واحدة منهن على عائشة رضي الله عنها لما قدمت البصرة فلم تأذن لها فيكون القصد هو الفاسد دون منع الولادة

miftah-dar-sacada §1214miftah-dar-sacadaArabic sense: الرضاع, رضاع

وطء المرأة إذا كانت ترضع وإنه يشبه قتل الولد سرا وأنه يدرك الفارس قيد عثره وقوله في حديث آخر لقد هممت أن أنهى عنه ثم رأيت فارس والروم يفعلونه ولا يضر ذلك أولادهم شيئا وقد قيل أن أحد الحديثين منسوخ بالآخر وإن لم تعلم عين الناسخ منها من المنسوخ لعدم علمنا بالتاريخ وقيل وهو أحسن أن النفي والإثبات لم يتواردا على محل واحد فإنه صلى الله عليه وسلم أخبر في أحد الجانبين أنه يفعل في الوليد مثل ما يفعل من يصرع الفارس عن فرسه كأنه يدعثره ويصرعه وذلك يوجب نوع أذى ولكنه ليس بقتل للولد وإهلاك له وإن كان قد يترتب عليه نوع أذى للطفل فأرشدهم إلى تركه ولم ينه عنه بل قال علام يفعل أحدكم ذلك ولم يقل لا تفعلوه فلم يجيء عنه لفظ واحد بالنهى عنه ثم عزم على النهى سدا لذريعة الأذى الذي ينال الرضيع فرأى أن سد هذه الذريعة لا يقاوم المفسدة التي تترتب على الإمساك عن وطء النساء مدة الرضاع ولا سيما

Research library

المكتبة البحثية480 works held

Peer-reviewed work held with its DOI and abstract, labelled with the study design its publication types report. None of it has been read or assessed, so nothing here may be cited as showing anything. Retracted work is held for the record but never listed; a review that a later version replaced is listed under its replacement and marked.

10.1111/j.1552-6909.2010.01211.xJournal of obstetric, gynecologic, and neonatal nursing : JOGNN (2011)MEDLINE-indexed journal, not yet read by us; matched on Breast Feeding, Infant Nutritional Physiological Phenomena, Infant Care, exclusive breastfeeding, breastfeeding, Infant, Newborn, Infant, Premature, Postnatal Care

The paradox of breastfeeding-associated morbidity among late preterm infants.: Objective: To synthesize the published research pertaining to breastfeeding establishment and outcomes among late preterm infants and to describe the state of the science on breastfeeding within this population. Data sources: Online databases Ovid MEDLINE, CINAHL, PubMed, and reference lists of reviewed articles. Study selection: Nine data-based research articles examining breastfeeding patterns and outcomes among infants born between 34 0/7 and 36 6/7 weeks gestation or overlapping with this ti

10.1542/peds.2018-3696Pediatrics (2020)MEDLINE-indexed journal, not yet read by us; matched on Breast Feeding, Milk, Human, Lactation, exclusive breastfeeding, breastfeeding, human milk, Infant, Newborn

Evidence-Based Updates on the First Week of Exclusive Breastfeeding Among Infants ≥35 Weeks.: The nutritional and immunologic properties of human milk, along with clear evidence of dose-dependent optimal health outcomes for both mothers and infants, provide a compelling rationale to support exclusive breastfeeding. US women increasingly intend to breastfeed exclusively for 6 months. Because establishing lactation can be challenging, exclusivity is often compromised in hopes of preventing feeding-related neonatal complications, potentially affecting the continuation and duration of breast

10.1002/14651858.cd011768.pub2The Cochrane database of systematic reviews (2018)MEDLINE-indexed journal, not yet read by us; matched on Breast Feeding, Infant Nutritional Physiological Phenomena, Weaning, exclusive breastfeeding, breastfeeding, Infant, Newborn

Educational interventions for improving primary caregiver complementary feeding practices for children aged 24 months and under.: Background: Although complementary feeding is a universal practice, the methods and manner in which it is practiced vary between cultures, individuals and socioeconomic classes. The period of complementary feeding is a critical time of transition in the life of an infant, and inappropriate complementary feeding practices, with their associated adverse health consequences, remain a significant global public health problem. Educational interventions are widely acknowledged as effective in promotin

10.1007/s10995-014-1526-8Maternal and child health journal (2015)MEDLINE-indexed journal, not yet read by us; matched on Breast Feeding, Infant Nutritional Physiological Phenomena, Infant Care, exclusive breastfeeding, breastfeeding, Infant, Newborn

Timing of breastfeeding initiation and exclusivity of breastfeeding during the first month of life: effects on neonatal mortality and morbidity--a systematic review and meta-analysis.: The purpose of this study was to review the evidence on the effect of initiation of breastfeeding early after birth and of exclusive breastfeeding during the first month in reducing neonatal mortality and morbidity. We searched Cochrane and PubMed databases for all available papers addressing our review questions and identified eleven papers. Data were extracted using a standard abstraction form. Evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation sy

10.1111/j.1740-8709.2012.00413.xMaternal & child nutrition (2013)MEDLINE-indexed journal, not yet read by us; matched on Breast Feeding, Infant Nutritional Physiological Phenomena, Weaning, breastfeeding, Infant, Newborn

Cluster-randomized trial on complementary and responsive feeding education to caregivers found improved dietary intake, growth and development among rural Indian toddlers.: Inadequate feeding and care may contribute to high rates of stunting and underweight among children in rural families in India. This cluster-randomized trial tested the hypothesis that teaching caregivers appropriate complementary feeding and strategies for how to feed and play responsively through home-visits would increase children's dietary intake, growth and development compared with home-visit-complementary feeding education alone or routine care. Sixty villages in Andhra Pradesh were rando

10.1002/14651858.cd004950.pub3The Cochrane database of systematic reviews (2012)MEDLINE-indexed journal, not yet read by us; matched on Breast Feeding, Milk, Human, Infant Care, breastfeeding, Infant, Newborn

Breastfeeding or breast milk for procedural pain in neonates.: Background: Physiological changes brought about by pain may contribute to the development of morbidity in neonates. Clinical studies have shown reduction in changes in physiological parameters and pain score measurements following pre-emptive analgesic administration in situations where the neonate is experiencing pain or stress. Non-pharmacological measures (such as holding, swaddling and breastfeeding) and pharmacological measures (such as acetaminophen, sucrose and opioids) have been used for

Research library, full list

351 to 375 of 480
Evenhouse E, Reilly S (2005)MEDLINE-indexed journal, not yet read by usHealth services research63 citations

Improved estimates of the benefits of breastfeeding using sibling comparisons to reduce selection bias.

Objective: Better measurement of the health and cognitive benefits of breastfeeding by using sibling comparisons to reduce sample selection bias. Data: We use data on the breastfeeding history, physical and emotional health, academic performance, cognitive ability, and demographic characteristics of 16,903 adolescents from the first (1994) wave of the National Longitudinal Study of Adolescent Health. The sample includes 2,734 sibling pairs. Study design: We examine the relationship between breastfeeding history and 15 indicators of physical health, emotional health, and cognitive ability, using ordinary least squares and logit regression. For each indicator, we estimate, in addition to the usual between-family model, a within-family model to see whether differences in siblings' outcomes are associated with differences in the siblings' breastfeeding histories. Principal findings: Nearly a

matched on Breast Feeding (mesh), breastfeeding (text)

Women, children and adolescents in conflict countries: an assessment of inequalities in intervention coverage and survival.

Introduction: Conflict adversely impacts health and health systems, yet its effect on health inequalities, particularly for women and children, has not been systematically studied. We examined wealth, education and urban/rural residence inequalities for child mortality and essential reproductive, maternal, newborn and child health interventions between conflict and non-conflict low-income and middle-income countries (LMICs). Methods: We carried out a time-series multicountry ecological study using data for 137 LMICs between 1990 and 2017, as defined by the 2019 World Bank classification. The data set covers approximately 3.8 million surveyed mothers (15-49 years) and 1.1 million children under 5 years including newborns (<1 month), young children (1-59 months) and school-aged children and adolescents (5-14 years). Outcomes include annual maternal and child mortality rates and coverage (%

matched on Breast Feeding (mesh), Infant, Newborn (mesh)

Williams CM, Cprek S, Asaolu I, English B, Jewell T, Smith K, Robl J (2017)MEDLINE-indexed journal, not yet read by usMaternal and child health journal22 citations

Kentucky Health Access Nurturing Development Services Home Visiting Program Improves Maternal and Child Health.

Background and objectives: Home visitation programs are one of the numerous efforts to help reduce the rates of preterm birth and low birth weight as well as offering other improvements in maternal and child health and development. The Kentucky Health Access Nurturing Development Services (HANDS) is a voluntary, home visiting program serving first-time, high-risk mothers. This study's objective was to evaluate the impact of HANDS on maternal and child health outcomes. Methods: HANDS administrative data, live birth certificate records and data from the Division of Child Protection and Safety were used in these analyses. We analyzed 2253 mothers who were referred to HANDS between July 2011 and June 2012 and received a minimum of one prenatal home visit (mean number of prenatal visits = 12.9) compared to a demographically similar group of women (n = 2253) who did not receive a visit. Chi sq

matched on Breast Feeding (mesh), Infant, Newborn (mesh)

Kayode GA, Ansah E, Agyepong IA, Amoakoh-Coleman M, Grobbee DE, Klipstein-Grobusch K (2014)MEDLINE-indexed journal, not yet read by usBMC pregnancy and childbirth73 citations

Individual and community determinants of neonatal mortality in Ghana: a multilevel analysis.

Background: Neonatal mortality is a global challenge; identification of individual and community determinants associated with it are important for targeted interventions. However in most low and middle income countries (LMICs) including Ghana this problem has not been adequately investigated as the impact of contextual factors remains undetermined despite their significant influence on under-five mortality and morbidity. Methods: Based on a modified conceptual framework for child survival, hierarchical modelling was deployed to examine about 6,900 women, aged 15 - 49 years (level 1), nested within 412 communities (level 2) in Ghana by analysing combined data of the 2003 and 2008 Ghana Demographic and Health Survey. The aim was to identify individual (maternal, paternal, neonatal, antenatal, delivery and postnatal) and community (socioeconomic disadvantage communities) determinants associ

matched on Breast Feeding (mesh), Infant, Newborn (mesh)

Clark S, Hamplová D (2013)MEDLINE-indexed journal, not yet read by usDemography56 citations

Single motherhood and child mortality in sub-Saharan Africa: a life course perspective.

Single motherhood in sub-Saharan Africa has received surprisingly little attention, although it is widespread and has critical implications for children's well-being. Using survival analysis techniques, we estimate the probability of becoming a single mother over women's life course and investigate the relationship between single motherhood and child mortality in 11 countries in sub-Saharan Africa. Although a mere 5 % of women in Ethiopia have a premarital birth, one in three women in Liberia will become mothers before first marriage. Compared with children whose parents were married, children born to never-married single mothers were significantly more likely to die before age 5 in six countries (odds ratios range from 1.36 in Nigeria to 2.61 in Zimbabwe). In addition, up to 50 % of women will become single mothers as a consequence of divorce or widowhood. In nine countries, having a fo

matched on Breast Feeding (mesh), Infant, Newborn (mesh)

Nelson AM, Bedford PJ (2016)MEDLINE-indexed journal, not yet read by usJournal of pediatric nursing24 citations

Mothering a Preterm Infant Receiving NIDCAP Care in a Level III Newborn Intensive Care Unit.

Unlabelled: The purpose of the study is to describe the unique meaning and significance of the essential elements of mothering a preterm infant receiving Newborn Individualized Developmental Care and Assessment Program (NIDCAP) care in a level III NICU. The overall aim was to promote an increased understanding among healthcare practitioners of the experience of this group of women. Design and methods: The authors utilized an existential-phenomenologic method to investigate the experience of 7 mothers of a preterm infant 30weeks gestation or less at birth. Results: Analysis of interview transcripts revealed one overarching theme, parenting with permission, and three essential themes with nine underlying subthemes: choosing to participate (subthemes: managing, settling in, making friends), dealing with people (subthemes: meeting needs, facing judgment, and recognizing not everyone is 'on b

matched on Infant Care (mesh), Intensive Care Units, Neonatal (mesh), Infant, Newborn (mesh), Infant, Premature (mesh)

Favalli EG, Biggioggero M, Crotti C, Becciolini A, Raimondo MG, Meroni PL (2019)reviewMEDLINE-indexed journal, not yet read by usClinical reviews in allergy & immunology158 citations

Sex and Management of Rheumatoid Arthritis.

Rheumatoid arthritis (RA) is a chronic and progressive autoimmune disease more common in women than men (3:1). Although sex-based differences may play a complex role in promoting an autoimmune dysfunction, to date the comprehensive knowledge of the link between sex and RA is still partially lacking. Furthermore, males and females have been demonstrated to differently deal with their chronic pathologies, modifying the perceived sex-based burden of disease. Gender medicine is a newly approach focusing on the impact of gender differences on human physiology, pathophysiology, and clinical features of diseases, analyzing the complex interrelation and integration of sex and psychological and cultural behavior. A better comprehension of possible factors influencing sexual dimorphism in RA susceptibility, pattern of presentation, disease activity, and outcome could contribute to a tailored appro

matched on Lactation (mesh)

Beauchemin KA (2018)reviewMEDLINE-indexed journal, not yet read by usJournal of dairy science189 citations

Invited review: Current perspectives on eating and rumination activity in dairy cows.

Many early studies laid the foundation for our understanding of the mechanics of chewing, the physiological role of chewing for the cow, and how chewing behavior is affected by dietary characteristics. However, the dairy cow has changed significantly over the past decades, as have the types of diets fed and the production systems used. The plethora of literature published in recent years provides new insights on eating and ruminating activity of dairy cows. Lactating dairy cows spend about 4.5 h/d eating (range: 2.4-8.5 h/d) and 7 h/d ruminating (range: 2.5-10.5 h/d), with a maximum total chewing time of 16 h/d. Chewing time is affected by many factors, most importantly whether access to feed is restricted, intake of neutral detergent fiber from forages, and mean particle size of the diet. Feed restriction and long particles (≥19 mm) have a greater effect on eating time, whereas intake o

matched on Lactation (mesh)

Bosch OJ (2013)reviewMEDLINE-indexed journal, not yet read by usPhilosophical transactions of the Royal Society of London. Series B, Biological sciences125 citations

Maternal aggression in rodents: brain oxytocin and vasopressin mediate pup defence.

The most significant social behaviour of the lactating mother is maternal behaviour, which comprises maternal care and maternal aggression (MA). The latter is a protective behaviour of the mother serving to defend the offspring against a potentially dangerous intruder. The extent to which the mother shows aggressive behaviour depends on extrinsic and intrinsic factors, as we have learned from studies in laboratory rodents. Among the extrinsic factors are the pups' presence and age, as well as the intruders' sex and age. With respect to intrinsic factors, the mothers' innate anxiety and the prosocial brain neuropeptides oxytocin (OXT) and arginine vasopressin (AVP) play important roles. While OXT is well known as a maternal neuropeptide, AVP has only recently been described in this context. The increased activities of these neuropeptides in lactation are the result of remarkable brain ada

matched on Lactation (mesh)

Neumann ID, Landgraf R (2012)reviewMEDLINE-indexed journal, not yet read by usTrends in neurosciences693 citations

Balance of brain oxytocin and vasopressin: implications for anxiety, depression, and social behaviors.

Oxytocin and vasopressin are regulators of anxiety, stress-coping, and sociality. They are released within hypothalamic and limbic areas from dendrites, axons, and perikarya independently of, or coordinated with, secretion from neurohypophysial terminals. Central oxytocin exerts anxiolytic and antidepressive effects, whereas vasopressin tends to show anxiogenic and depressive actions. Evidence from pharmacological and genetic association studies confirms their involvement in individual variation of emotional traits extending to psychopathology. Based on their opposing effects on emotional behaviors, we propose that a balanced activity of both brain neuropeptide systems is important for appropriate emotional behaviors. Shifting the balance between the neuropeptide systems towards oxytocin, by positive social stimuli and/or psychopharmacotherapy, may help to improve emotional behaviors and

matched on Lactation (mesh)

Nishimori K, Takayanagi Y, Yoshida M, Kasahara Y, Young LJ, Kawamata M (2008)reviewMEDLINE-indexed journal, not yet read by usProgress in brain research78 citations

New aspects of oxytocin receptor function revealed by knockout mice: sociosexual behaviour and control of energy balance.

To further define the function of the oxytocin receptor (OXTR) in vivo, we generated mice deficient in the Oxtr gene (Oxtr-/-). Oxtr-/- mice had no obvious deficits in fertility or sexual behaviour, but displayed several aberrations in social behaviours, including male aggression, and mother-offspring interaction. In addition, they showed novel physiological defects including obesity, and dysfunction in body temperature control when exposed to cold. We review here our new findings with Oxtr-/- mice, and introduce newly generated Oxtr-Venus knockin mice as a potential tool for examining molecular physiology of Oxtr-neurons.

matched on Lactation (mesh)

Plaizier JC, Krause DO, Gozho GN, McBride BW (2008)reviewMEDLINE-indexed journal, not yet read by usVeterinary journal (London, England : 1997)526 citations

Subacute ruminal acidosis in dairy cows: the physiological causes, incidence and consequences.

During subacute ruminal acidosis (SARA) rumen pH is depressed for several hours per day due to accumulation of volatile fatty acids and insufficient rumen buffering. Surveys suggested an incidence of SARA of between 19% and 26% in early and mid-lactation dairy cows. Causes of SARA include feeding excessive amounts of non-structural carbohydrates and highly fermentable forages, and insufficient dietary coarse fiber. Consequences of SARA include feed intake depression, reduced fiber digestion, milk fat depression, diarrhea, laminitis, liver abscesses, increased production of bacterial endotoxin and inflammation characterized by increases in acute phase proteins. The increase in endotoxin is similar among methods for SARA induction, but depends on the diet fed before induction. Increases in acute phase proteins vary among methods of SARA induction, even when the methods result in similar ru

matched on Lactation (mesh)

Braithwaite M (2008)reviewMEDLINE-indexed journal, not yet read by usAdvances in neonatal care : official journal of the National Association of Neonatal Nurses95 citations

Nurse burnout and stress in the NICU.

The effects of nurse burnout and stress in a neonatal intensive care unit (NICU)-high levels of absenteeism, low morale, mental fatigue, and exhaustion-can have detrimental effects on neonatal care. Because of the nature of this highly specialized form of nursing, NICU nurses can experience high levels of psychologic and physical stress. Burnout is a response to workplace stress that results in emotional and mental exhaustion, depersonalization, and decreased sense of personal accomplishment. Job satisfaction, emotional support, and self-care are important components for preventing burnout in staff. Therefore, the implications regarding practice and nurse burnout in the NICU are clear. It is the responsibility of both individual nurses and administrative leaders to take the necessary steps to prevent nurse burnout. Preventing this phenomenon in the NICU can lead to better retention and r

matched on Intensive Care Units, Neonatal (mesh)

Brunton PJ, Russell JA, Douglas AJ (2008)reviewMEDLINE-indexed journal, not yet read by usJournal of neuroendocrinology198 citations

Adaptive responses of the maternal hypothalamic-pituitary-adrenal axis during pregnancy and lactation.

Over the past 40 years, it has been recognised that the maternal hypothalamic-pituitary-adrenal (HPA) axis undergoes adaptations through pregnancy and lactation that might contribute to avoidance of adverse effects of stress on the mother and offspring. The extent of the global adaptations in the HPA axis has been revealed and the underlying mechanisms investigated within the last 20 years. Both basal, including the circadian rhythm, and stress-induced adrenocorticotrophic hormone and glucocorticoid secretory patterns are altered. Throughout most of pregnancy, and in lactation, these changes predominantly reflect reduced drive by the corticotropin-releasing factor (CRF) neurones in the parvocellular paraventricular nucleus (pPVN). An accompanying profound attenuation of HPA axis responses to a wide variety of psychological and physical stressors emerges after mid-pregnancy and persists u

matched on Lactation (mesh)

Leng G, Onaka T, Caquineau C, Sabatier N, Tobin VA, Takayanagi Y (2008)reviewMEDLINE-indexed journal, not yet read by usProgress in brain research81 citations

Oxytocin and appetite.

Oxytocin has potent central effects on feeding behaviour, as well as on social and sexual behaviours, and one likely substrate for its anorectic effect is the ventromedial nucleus of the hypothalamus. This nucleus expresses a high density of oxytocin receptors, but contains very few oxytocin-containing fibres, hence it is a likely target of 'neurohormonal' actions of oxytocin, including possibly oxytocin released from the dendrites of magnocellular oxytocin neurones. As oxytocin release from dendrites is regulated independent of electrical activity and of secretion from the neurohypophysis, exactly how this release is regulated by metabolic and reproduction-related signals remains to be established fully. Intriguingly though, it looks as though this central release of oxytocin from magnocellular neurons might be instrumental in a fundamental shift in motivational behaviour - switching be

matched on Lactation (mesh)

Kosnett MJ, Wedeen RP, Rothenberg SJ, Hipkins KL, Materna BL, Schwartz BS, Hu H, Woolf A (2007)reviewMEDLINE-indexed journal, not yet read by usEnvironmental health perspectives199 citations

Recommendations for medical management of adult lead exposure.

Research conducted in recent years has increased public health concern about the toxicity of lead at low dose and has supported a reappraisal of the levels of lead exposure that may be safely tolerated in the workplace. In this article, which appears as part of a mini-monograph on adult lead exposure, we summarize a body of published literature that establishes the potential for hypertension, effects on renal function, cognitive dysfunction, and adverse female reproductive outcome in adults with whole-blood lead concentrations < 40 microg/dL. Based on this literature, and our collective experience in evaluating lead-exposed adults, we recommend that individuals be removed from occupational lead exposure if a single blood lead concentration exceeds 30 microg/dL or if two successive blood lead concentrations measured over a 4-week interval are > or = 20 microg/dL. Removal of individuals fr

matched on Lactation (mesh)

Rahman M, Haque SE, Zahan S, Islam O (2011)MEDLINE-indexed journal, not yet read by usJournal of obstetric, gynecologic, and neonatal nursing : JOGNN22 citations

Noninstitutional births and newborn care practices among adolescent mothers in Bangladesh.

Objective: To describe home-based newborn care practices among adolescent mothers in Bangladesh and to identify sociodemographic, antenatal care (ANC), and delivery care factors associated with these practices. Design: The 2007 Bangladesh Demographic Health Survey, conducted from March 24 to August 11, 2007. Setting: Selected urban and rural areas of Bangladesh. Participants: A total of 580 adolescent women (aged 15-19 years) who had ever been married with noninstitutional births and having at least one child younger than 3 years of age. Methods: Outcomes included complete cord care, complete thermal protection, initiation of early breastfeeding, and postnatal care within 24 hours of birth. Descriptive statistics and multivariate logistic regression methods were employed in analyzing the data. Results: Only 42.8% and 5.1% newborns received complete cord care and complete thermal protecti

matched on Infant Care (mesh), breastfeeding (text), Infant, Newborn (mesh), Postnatal Care (mesh)

Berger S, Oesterle I, Ayeni KI, Ezekiel CN, Rompel A, Warth B (2024)MEDLINE-indexed journal, not yet read by usAnalytical and bioanalytical chemistry9 citations

Polyphenol exposure of mothers and infants assessed by LC-MS/MS based biomonitoring in breast milk.

Exposure to polyphenols is relevant throughout critical windows of infant development, including the breastfeeding phase. However, the quantitative assessment of polyphenols in human breast milk has received limited attention so far, though polyphenols may positively influence infant health. Therefore, a targeted LC-MS/MS assay was developed to investigate 86 analytes representing different polyphenol classes in human breast milk. The sample preparation consisted of liquid extraction, salting out, freeze-out, and a dilution step. Overall, nearly 70% of the chemically diverse polyphenols fulfilled all strict validation criteria for full quantitative assessment. The remaining analytes did not fulfill all criteria at every concentration level, but can still provide useful semi-quantitative insights into nutritional and biomedical research questions. The limits of detection for all analyzed

matched on Milk, Human (mesh), breastfeeding (text)

Lerrer B, Zinger-Yosovich KD, Avrahami B, Gilboa-Garber N (2007)MEDLINE-indexed journal, not yet read by usThe ISME journal30 citations

Honey and royal jelly, like human milk, abrogate lectin-dependent infection-preceding Pseudomonas aeruginosa adhesion.

Pseudomonas aeruginosa antibiotic resistance has led to the search of natural compounds, which would competitively block its fucose>fructose/mannose-binding lectin (PA-IIL) that mediates its biofilm formation and adhesion to animal cells. Such compounds were found in human milk (HM) and avian egg whites. The present research has revealed that honey and royal jelly (RJ), which are assigned to protect beehive progeny and are applied for human infection therapy, match HM in PA-IIL blocking. The function of their fructose (higher in honey) and mannosylated glycoproteins (higher in RJ) as powerful decoys in PA-IIL neutralization is of ecological/biological importance and implementability for the antibacterial adhesion therapeutic strategy.

matched on Milk, Human (mesh), human milk (text)

Munns LB, Preston C (2025)MEDLINE-indexed journal, not yet read by usJournal of neuropsychology8 citations

The role of bodily experiences during pregnancy on mother and infant outcomes.

Pregnancy is a transformative time for women and their bodies, and therefore thoughts and feelings and about one's own body and internal bodily sensations may understandably change during this period. Body satisfaction and interoception have been found to influence factors such as antenatal attachment (AA) and maternal mental health. However, mixed results in the literature suggest complex relationships between the bodily experience during pregnancy and outcomes, necessitating a broader investigative approach. We aim to examine the relationship between the pregnancy bodily experience and multiple mother-infant outcomes. It is hypothesised that poor bodily experiences during pregnancy will have negative impacts on these outcomes. Cross-sectional online survey data was collected from individuals at various gestations throughout pregnancy as part of a larger longitudinal study (N = 253, mea

matched on Breast Feeding (mesh)

Hackett KM, Mukta US, Jalal CS, Sellen DW (2015)MEDLINE-indexed journal, not yet read by usMaternal & child nutrition39 citations

Knowledge, attitudes and perceptions on infant and young child nutrition and feeding among adolescent girls and young mothers in rural Bangladesh.

Improved infant and young child feeding (IYCF) practices have the potential to improve child health and development outcomes in poorly resourced communities. In Bangladesh, approximately 60% of rural girls become mothers before the age of 18, but most interventions to improve IYCF practices target older mothers. We investigated the knowledge, attitudes and perceptions regarding IYCF among adolescent girls and young women aged 15-23 years old in two rural regions in north-west Bangladesh and identified the main points of concordance with, or mismatch to, key international IYCF recommendations. We compared qualitative data collected during interviews and focus groups with participants who were unmarried, married without a child and married with at least one child, and stratified by region. Qualitative indicators of concordance with international recommendations suggest that IYCF knowledge

matched on Breast Feeding (mesh)

Elliott L, Henderson J, Northstone K, Chiu GY, Dunson D, London SJ (2008)MEDLINE-indexed journal, not yet read by usThe Journal of allergy and clinical immunology70 citations

Prospective study of breast-feeding in relation to wheeze, atopy, and bronchial hyperresponsiveness in the Avon Longitudinal Study of Parents and Children (ALSPAC).

Background: Breast-feeding clearly protects against early wheezing, but recent data suggest that it might increase later risk of atopic disease and asthma. Objective: We sought to examine the relationship between breast-feeding and later asthma and allergy outcomes by using data from the Avon Longitudinal Study of Parents and Children, a large birth cohort in the United Kingdom. Methods: We used adjusted logistic regression models to evaluate the association between breast-feeding and atopy at age 7 years, bronchial responsiveness to methacholine at age 8 years, and wheeze at ages 3 and 7 1/2 years. Bayesian methods were used to assess the possibility of bias caused by an influence of early wheezing on the duration of breast-feeding, as well as selection bias. Results: Breast-feeding was protective for wheeze in the first 3 years of life (odds ratio [OR] of 0.80 [95% CI, 0.70-0.90] for >

matched on Breast Feeding (mesh)

Robinson KJ, Hazon N, Twiss SD, Pomeroy PP (2019)MEDLINE-indexed journal, not yet read by usPsychoneuroendocrinology4 citations

High oxytocin infants gain more mass with no additional maternal energetic costs in wild grey seals (Halichoerus grypus).

Maximising infant survival requires secure attachments and appropriate behaviours between parents and offspring. Oxytocin is vital for parent-offspring bonding and behaviour. It also modulates energetic balance and neural pathways regulating feeding. However, to date the connections between these two areas of the hormone's functionality are poorly defined. We demonstrate that grey seal (Halichoerus grypus) mothers with high oxytocin levels produce pups with high oxytocin levels throughout lactation, and show for the first time a link between endogenous infant oxytocin levels and rates of mass gain prior to weaning. High oxytocin infants gained mass at a greater rate without additional energetic cost to their mothers. Increased mass gain in infants was not due to increased nursing, and there was no link between maternal mass loss rates and plasma oxytocin concentrations. Increased mass ga

matched on Weaning (mesh), Lactation (mesh)

Paul HA, Bomhof MR, Vogel HJ, Reimer RA (2016)MEDLINE-indexed journal, not yet read by usScientific reports142 citations

Diet-induced changes in maternal gut microbiota and metabolomic profiles influence programming of offspring obesity risk in rats.

Maternal obesity and overnutrition during pregnancy and lactation can program an increased risk of obesity in offspring. In this context, improving maternal metabolism may help reduce the intergenerational transmission of obesity. Here we show that, in Sprague-Dawley rats, selectively altering obese maternal gut microbial composition with prebiotic treatment reduces maternal energy intake, decreases gestational weight gain, and prevents increased adiposity in dams and their offspring. Maternal serum metabolomics analysis, along with satiety hormone and gut microbiota analysis, identified maternal metabolic signatures that could be implicated in programming offspring obesity risk and highlighted the potential influence of maternal gut microbiota on maternal and offspring metabolism. In particular, the metabolomic signature of insulin resistance in obese rats normalized when dams consumed

matched on Weaning (mesh), Lactation (mesh)

Cleveland LM, Bonugli R (2014)MEDLINE-indexed journal, not yet read by usJournal of obstetric, gynecologic, and neonatal nursing : JOGNN72 citations

Experiences of mothers of infants with neonatal abstinence syndrome in the neonatal intensive care unit.

Objective: To describe the experiences of mothers of infants with neonatal abstinence syndrome (NAS) in the neonatal intensive care unit (NICU). Design: Qualitative description. Setting: We recruited participants from community-based, out-patient, addiction treatment facilities in a large urban city in the southwestern region of the United States. Participants: A convenience sample of 15 Hispanic, substance addicted mothers of infants with NAS participated. Methods: We conducted semistructured, individual, interviews and analyzed the data using qualitative content analysis. First, we analyzed the data independently and then discussed the themes until a consensus was reached. Results: We identified four themes: (a) understanding addiction, (b) watching the infant withdraw, (c) judging, and (d) trusting the nurses. The participants felt there was a lack of understanding concerning addictio

matched on Infant Care (mesh), Intensive Care Units, Neonatal (mesh), Infant, Newborn (mesh)

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