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Childhood adversity

Early adverse experience and its life course effects.

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Qurʾān

القرآن6 shown

Verses named for this subject by hand come first. The rest are found by the subject’s own Arabic and English senses and are shown as lexical matches, not as anchors anyone has confirmed.

Qur'ān 107:2Arabic sense: اليتيم, يتيم

فَذَٰلِكَ ٱلَّذِي يَدُعُّ ٱلۡيَتِيمَ

It is he who pushes aside the orphan

Qur'ān 17:34Arabic sense: اليتيم, يتيم

وَلَا تَقۡرَبُواْ مَالَ ٱلۡيَتِيمِ إِلَّا بِٱلَّتِي هِيَ أَحۡسَنُ حَتَّىٰ يَبۡلُغَ أَشُدَّهُۥۚ وَأَوۡفُواْ بِٱلۡعَهۡدِۖ إِنَّ ٱلۡعَهۡدَ كَانَ مَسۡـُٔولࣰ ا

Do not go near the orphan’s property, except with the best [intentions], until he reaches the age of maturity. Honour your pledges: you will be questioned about your pledges

Qur'ān 6:152Arabic sense: اليتيم, يتيم

وَلَا تَقۡرَبُواْ مَالَ ٱلۡيَتِيمِ إِلَّا بِٱلَّتِي هِيَ أَحۡسَنُ حَتَّىٰ يَبۡلُغَ أَشُدَّهُۥۚ وَأَوۡفُواْ ٱلۡكَيۡلَ وَٱلۡمِيزَانَ بِٱلۡقِسۡطِۖ لَا نُكَلِّفُ نَفۡسًا إِلَّا وُسۡعَهَاۖ وَإِذَا قُلۡتُمۡ فَٱعۡدِلُواْ وَلَوۡ كَانَ ذَا قُرۡبَىٰۖ وَبِعَهۡدِ ٱللَّهِ أَوۡفُواْۚ ذَٰلِكُمۡ وَصَّىٰكُم بِهِۦ لَعَلَّكُمۡ تَذَكَّرُونَ

Stay well away from the property of orphans, except with the best [intentions], until they come of age; give full measure and weight, according to justice’- We do not burden any soul with more than it can bear- ‘ when you speak, be just, even if it concerns a relative; keep any promises you make in God’s name. This is what He commands you to do, so that you may take heed’

Qur'ān 89:17Arabic sense: اليتيم, يتيم

كَلَّاۖ بَل لَّا تُكۡرِمُونَ ٱلۡيَتِيمَ

No indeed! You [people] do not honour orphans

Qur'ān 93:9Arabic sense: اليتيم, يتيم

فَأَمَّا ٱلۡيَتِيمَ فَلَا تَقۡهَرۡ

So do not be harsh with the orphan

Qur'ān 18:82Arabic sense: يتيم

وَأَمَّا ٱلۡجِدَارُ فَكَانَ لِغُلَٰمَيۡنِ يَتِيمَيۡنِ فِي ٱلۡمَدِينَةِ وَكَانَ تَحۡتَهُۥ كَنزࣱ لَّهُمَا وَكَانَ أَبُوهُمَا صَٰلِحࣰ ا فَأَرَادَ رَبُّكَ أَن يَبۡلُغَآ أَشُدَّهُمَا وَيَسۡتَخۡرِجَا كَنزَهُمَا رَحۡمَةࣰ مِّن رَّبِّكَۚ وَمَا فَعَلۡتُهُۥ عَنۡ أَمۡرِيۚ ذَٰلِكَ تَأۡوِيلُ مَا لَمۡ تَسۡطِع عَّلَيۡهِ صَبۡرࣰ ا

The wall belonged to two young orphans in the town and there was buried treasure beneath it belonging to them. Their father had been a righteous man, so your Lord intended them to reach maturity and then dig up their treasure as a mercy from your Lord. I did not do [these things] of my own accord: these are the explanations for those things you could not bear with patience.’

Tafsīr

التفسير6 shown

Commentary on the verses above, at most two editions per verse.

en-al-jalalayn on 17:34en-al-jalalayncommentary on an ayah this subject surfaced

And do not come anywhere near an orphan’s property except in the fairest manner until he comes of age. And fulfil the covenant should you make a covenant with God or with people in general. Indeed the covenant will be enquired into.

en-al-jalalayn on 6:152en-al-jalalayncommentary on an ayah this subject surfaced

And that you do not approach the property of the orphan save with that approach which is fairer namely the one wherein lie his best interests until he is of age when he is sexually mature. And give full measure and full weight in justice fairly desisting from any fraud. We do not charge any soul beyond its capacity what it can bear in such matters so that if one makes a mistake in a measure or weight and God knows that his intention had been well-meaning then he suffers no blame as is stated in one hadīth. And if you speak to pass a judgement or otherwise then be just by being truthful even if he the person receiving the statement or the one being accused in it should be a kinsman. And fulfil God’s covenant. This is what He has charged you with that perhaps you will remember read tadhakkarūn or tadhkurūn you will be admonished.

en-al-jalalayn on 89:17en-al-jalalayncommentary on an ayah this subject surfaced

No indeed! — a disavowal of this notion in other words honour is not about wealth nor is there any humiliation in poverty rather it has to do with obedience and disobedience respectively; but the disbelievers of Mecca unmindful of this. Rather they do not honour the orphan they do not treat him with kindness despite their wealth or it means that they do not give him what is his due from an inheritance

en-tafisr-ibn-kathir on 17:34en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

And come not near to the orphan's property except to improve it, until he attains the age of full strength. And fulfill (every) covenant. Verily, the covenant will be questioned about (34)And give full measure when you measure, and weigh with a balance that is straight. That is good (advantageous) and better in the end (35) The Command to handle the Orphan's Wealth properly and to be Honest in Weights and Measures وَلَا تَقْرَبُوا مَالَ الْيَتِيمِ إِلَّا بِالَّتِي هِيَ أَحْسَنُ حَتَّىٰ يَبْلُغَ أَشُدَّهُ (And come not near to the orphan's property except to improve it, until he attains the age of full strength.) meaning, do not dispose of the orphan's wealth except in a proper manner. وَلَا تَأْكُلُوهَا إِسْرَافًا وَبِدَارًا أَن يَكْبَرُوا ۚ وَمَن كَانَ غَنِيًّا فَلْيَسْتَعْفِفْ ۖ وَمَن كَانَ فَقِيرًا فَلْيَأْكُلْ بِالْمَعْرُوفِ (but consume it [the orphan's property] not wastefully

en-tafisr-ibn-kathir on 6:152en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

"And come not near to the orphan's property, except to improve it, until he (or she) attains the age of full strength; and give full measure and full weight with justice." – We burden not any person, but that which he can bear – "And whenever you speak, say the truth even if a near relative is concerned, and fulfill the covenant of Allah. This He commands you, that you may remember. (152) The Prohibition of Consuming the Orphan's Property Ata' bin As-Sa'ib said that Sa'id bin Jubayr said that Ibn 'Abbas said, "When Allah revealed, وَلَا تَقْرَبُوا مَالَ الْيَتِيمِ إِلَّا بِالَّتِي هِيَ أَحْسَنُ (And come not near to the orphan's property, except to improve it.) and, إِنَّ الَّذِينَ يَأْكُلُونَ أَمْوَالَ الْيَتَامَىٰ ظُلْمًا (Verily, those who unjustly eat up the property of orphans.)[4:10] those who were guardians of orphans separated their food from the orphans' food and their dri

en-tafisr-ibn-kathir on 89:17en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

As for man, when his Lord tries him by giving him honor and bounties, then he says: "My Lord has honored me. (15)But when He tries him by straitening his means of life, he says: "My Lord has humiliated me! (16)But no! But you treat not the orphans with kindness and generosity (17)And urge not one another on the feeding of the Miskin (18)And you devour the Turath – devouring with greed (19)And you love wealth with love Jamma (20) Wealth and Poverty are both a Test and Honor or Disgrace for the Servant Allah refutes man in his belief that if Allah gives Him abundant provisions to test him with it, it is out of His honor for him. But this is not the case, rather it is a trial and a test, as Allah says, أَيَحْسَبُونَ أَنَّمَا نُمِدُّهُم بِهِ مِن مَّالٍ وَبَنِينَ - نُسَارِعُ لَهُمْ فِي الْخَيْرَاتِ ۚ بَل لَّا يَشْعُرُونَ (Do they think that in wealth and children with which We enlarge the

Ḥadīth

الحديث6 shown

Sound narrations only, and never matched by text. A narration appears here because a compiler filed it under a chapter this subject maps to, or because someone read it and anchored it. Each row says which.

Sunan an-Nasa'i 4212Al-'Aqiqahfiled here by the compiler

أَخْبَرَنَا أَحْمَدُ بْنُ سُلَيْمَانَ، قَالَ حَدَّثَنَا أَبُو نُعَيْمٍ، قَالَ حَدَّثَنَا دَاوُدُ بْنُ قَيْسٍ، عَنْ عَمْرِو بْنِ شُعَيْبٍ، عَنْ أَبِيهِ، عَنْ جَدِّهِ، قَالَ سُئِلَ رَسُولُ اللَّهِ صلى الله عليه وسلم عَنِ الْعَقِيقَةِ فَقَالَ ‏"‏ لاَ يُحِبُّ اللَّهُ عَزَّ وَجَلَّ الْعُقُوقَ ‏"‏ ‏.‏ وَكَأَنَّهُ كَرِهَ الاِسْمَ قَالَ لِرَسُولِ اللَّهِ صلى الله عليه وسلم إِنَّمَا نَسْأَلُكَ أَحَدُنَا يُولَدُ لَهُ ‏.‏ قَالَ ‏"‏ مَنْ أَحَبَّ أَنْ يَنْسُكَ عَنْ وَلَدِهِ فَلْيَنْسُكْ عَنْهُ عَنِ الْغُلاَمِ شَاتَانِ مُكَافَأَتَانِ وَعَنِ الْجَارِيَةِ شَاةٌ ‏"‏ ‏.‏ قَالَ دَاوُدُ سَأَلْتُ زَيْدَ بْنَ أَسْلَمَ عَنِ الْمُكَافَأَتَانِ قَالَ الشَّاتَانِ الْمُشَبَّهَتَانِ تُذْبَحَانِ جَمِيعًا ‏.‏

It was narrated from 'Amr bin Shuaib, from his fahther, that his grandfather said:"The messenger of Allah was asked about the 'Aqiqah and he said: "Allah, the mighty and sublime, does not like Al-Uquq' as if he disliked the word (Al-Aqiqah). He said to the Messenger of Allah: 'But one of us may offer a sacrifice when a child is born to him.' He said: 'Whoever wants to offer a sacrifice for his child, let him do so, for a boy; two sheep, Mukafaatan, (of equal age), and for a girl, one.' (One of the narrators) Dawud said: 'I asked Ziad bin Aslam about the word Mukafaatan and he said: 'Two similar sheep that are slaughtered together

Sunan an-Nasa'i 4213Al-'Aqiqahfiled here by the compiler

أَخْبَرَنَا الْحُسَيْنُ بْنُ حُرَيْثٍ، قَالَ حَدَّثَنَا الْفَضْلُ، عَنِ الْحُسَيْنِ بْنِ وَاقِدٍ، عَنْ عَبْدِ اللَّهِ بْنِ بُرَيْدَةَ، عَنْ أَبِيهِ، أَنَّ رَسُولَ اللَّهِ صلى الله عليه وسلم عَقَّ عَنِ الْحَسَنِ وَالْحُسَيْنِ ‏.‏

It was narrated from 'Abdullah bin Buraidah, from his father, that:the Messenger of Allah offered the 'Aqiqah for Al-Hasan and Al-Husain

Jami' at-Tirmidhi 1146The Book On Sucklingfiled here by the compiler

حَدَّثَنَا أَحْمَدُ بْنُ مَنِيعٍ، حَدَّثَنَا إِسْمَاعِيلُ بْنُ إِبْرَاهِيمَ، حَدَّثَنَا عَلِيُّ بْنُ زَيْدٍ، عَنْ سَعِيدِ بْنِ الْمُسَيَّبِ، عَنْ عَلِيِّ بْنِ أَبِي طَالِبٍ، قَالَ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏ "‏ إِنَّ اللَّهَ حَرَّمَ مِنَ الرَّضَاعِ مَا حَرَّمَ مِنَ النَّسَبِ ‏"‏ ‏.‏ قَالَ وَفِي الْبَابِ عَنْ عَائِشَةَ وَابْنِ عَبَّاسٍ وَأُمِّ حَبِيبَةَ ‏.‏ قَالَ أَبُو عِيسَى حَدِيثُ عَلِيٍّ حَسَنٌ صَحِيحٌ ‏.‏

Ali (bin Abi Talib) narrated that The Messenger of Allah said:“Indeed Allah has made unlawful through suckling whatever He made unlawful through lineage.”

Jami' at-Tirmidhi 1147The Book On Sucklingfiled here by the compiler

حَدَّثَنَا بُنْدَارٌ، حَدَّثَنَا يَحْيَى بْنُ سَعِيدٍ الْقَطَّانُ، حَدَّثَنَا مَالِكٌ، ح وَحَدَّثَنَا إِسْحَاقُ بْنُ مُوسَى الأَنْصَارِيُّ، قَالَ حَدَّثَنَا مَعْنٌ، قَالَ حَدَّثَنَا مَالِكٌ، عَنْ عَبْدِ اللَّهِ بْنِ دِينَارٍ، عَنْ سُلَيْمَانَ بْنِ يَسَارٍ، عَنْ عُرْوَةَ بْنِ الزُّبَيْرِ، عَنْ عَائِشَةَ، قَالَتْ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏ "‏ إِنَّ اللَّهَ حَرَّمَ مِنَ الرَّضَاعَةِ مَا حَرَّمَ مِنَ الْوِلاَدَةِ ‏"‏ ‏.‏ قَالَ أَبُو عِيسَى هَذَا حَدِيثٌ حَسَنٌ صَحِيحٌ ‏.‏ وَالْعَمَلُ عَلَى هَذَا عِنْدَ أَهْلِ الْعِلْمِ مِنْ أَصْحَابِ النَّبِيِّ صلى الله عليه وسلم وَغَيْرِهِمْ لاَ نَعْلَمُ بَيْنَهُمْ فِي ذَلِكَ اخْتِلاَفًا ‏.‏

Aishah narrated that the Messenger of Allah said:“Indeed Allah has made unlawful through suckling whatever He made unlawful through birth.”

Sahih Muslim 1444Sucklingfiled here by the compiler

حَدَّثَنَا يَحْيَى بْنُ يَحْيَى، قَالَ قَرَأْتُ عَلَى مَالِكٍ عَنْ عَبْدِ اللَّهِ بْنِ أَبِي بَكْرٍ، عَنْ عَمْرَةَ، أَنَّ عَائِشَةَ، أَخْبَرَتْهَا أَنَّ رَسُولَ اللَّهِ صلى الله عليه وسلم كَانَ عِنْدَهَا وَإِنَّهَا سَمِعَتْ صَوْتَ رَجُلٍ يَسْتَأْذِنُ فِي بَيْتِ حَفْصَةَ ‏.‏ قَالَتْ عَائِشَةُ فَقُلْتُ يَا رَسُولَ اللَّهِ هَذَا رَجُلٌ يَسْتَأْذِنُ فِي بَيْتِكَ ‏.‏ فَقَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏"‏ أُرَاهُ فُلاَنًا ‏"‏ ‏.‏ لِعَمِّ حَفْصَةَ مِنَ الرَّضَاعَةِ ‏.‏ فَقَالَتْ عَائِشَةُ يَا رَسُولَ اللَّهِ لَوْ كَانَ فُلاَنٌ حَيًّا - لِعَمِّهَا مِنَ الرَّضَاعَةِ - دَخَلَ عَلَىَّ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏"‏ نَعَمْ إِنَّ الرَّضَاعَةَ تُحَرِّمُ مَا تُحَرِّمُ الْوِلاَدَةُ ‏"‏ ‏.‏

A'isha (Allah be pleased with her) reported tha Allah's Messenger (ﷺ) was with her and she heard the voice of a person seeking permission to enter the house of Hafsa. 'A'isha (Allah he pleased with her) said:Allah's Messenger, he is the person who seeks permission to enter your house, whereupon Allah's Messenger (ﷺ) said: I think he is so and so (uncle of Hafsa by reason of fosterage). 'A'isha said: Messenger of Allah, if so and so (her uncle by reason of fosterage) were alive, could he enter my house? Allah's Messenger (ﷺ) said: Yes. Fosterage makes unlawful what consanguinity makes unlawful

Sahih Muslim 1445Sucklingfiled here by the compiler

حَدَّثَنَا يَحْيَى بْنُ يَحْيَى، قَالَ قَرَأْتُ عَلَى مَالِكٍ عَنِ ابْنِ شِهَابٍ، عَنْ عُرْوَةَ بْنِ الزُّبَيْرِ، عَنْ عَائِشَةَ، أَنَّهَا أَخْبَرَتْهُ أَنَّ أَفْلَحَ - أَخَا أَبِي الْقُعَيْسِ - جَاءَ يَسْتَأْذِنُ عَلَيْهَا وَهُوَ عَمُّهَا مِنَ الرَّضَاعَةِ بَعْدَ أَنْ أُنْزِلَ الْحِجَابُ قَالَتْ فَأَبَيْتُ أَنْ آذَنَ لَهُ فَلَمَّا جَاءَ رَسُولُ اللَّهِ صلى الله عليه وسلم أَخْبَرْتُهُ بِالَّذِي صَنَعْتُ فَأَمَرَنِي أَنْ آذَنَ لَهُ عَلَىَّ ‏.‏

A'isha (Allah be pleased with her) reported that Aflah, the brother of Abu'l-Qu'ais, who was her uncle by reason of fosterage, came, and asked her permission (to enter the house) after seclusion (Hijab) was instituted. I refused to admit him. When Allah's Messenger (ﷺ) came, I informed him what I had done. He commanded me to grant him permission (as the brother of her foster-father was also her uncle)

Classical works

كتب التراث6 shown

Arabic originals, reached through the subject’s Arabic senses. Interpretive sources, never proof of a ruling.

riyad-salihin §2072riyad-salihinArabic sense: اليتامى, اليتيم, يتامي, يتيم

قال الله تعالى إن الذين يأكلون أموال اليتامى ظلما إنما يأكلون في بطونهم نارا وسيصلون سعيرا النساء وقال تعالى ولا تقربوا مال اليتيم إلا بالتي هي أحسن الانعام وقال تعالى ويسألونك عن اليتامى قل إصلاح لهم خير وإن تخالطوهم فإخوانكم والله يعلم المفسد من المصلح البقرة

ihya §9101ihyaArabic sense: اليتامى, اليتيم, يتامي, يتيم

الفائدة العاشرة أن يتمكن من الإيثار والتصدق بما فضل من الأطعمة على اليتامى والمساكين فيكون يوم القيامة في ظل صدقته + حديث كل امرئ في ظل صدقته أخرجه الحاكم من حديث عقبة بن عامر وقد تقدم + كما ورد به الخبر فما يأكله كان خزانته الكنيف وما يتصدق به كان خزانته فضل الله تعالى فليس للعبد من ماله إلا ما تصدق فأبقى أو أكل فأفنى أو لبس فأبلى فالتصدق بفضلات الطعام أولى من التخمة والشبع وكان الحسن رحمة الله عليه إذا تلا قوله تعالى إنا عرضنا الأمانة على السموات والأرض والجبال فأبين أن يحملنها وأشفقن منها وحملها الإنسان إنه كان ظلوما جهولا قال عرضها على السموات السبع الطباق والطرائق التي زينها بالنجوم وحملة العرش العظيم فقال لها سبحانه وتعالى هل تحملين الأمانة بما فيها قالت وما فيها قال إن أحسنت جوزيت وإن أسأت عوقبت فقالت لا ثم عرضها كذلك على الأرض فأبت ثم عرضها على الجبال الشوامخ الصلاب الصعاب فقال لها هل تحملين الأمانة بما فيها قالت وما فيها فذكر الجزاء والعقوبة فقالت لا ثم عرضها على الإنسان فحملها

jami-ulum §135jami-ulumArabic sense: اليتامى, اليتيم, يتامي, يتيم

جحيفة قال جاء رجل إلى النبي صلى الله عليه وسلم يشكو جاره فقال له اطرح متاعك في الطريق قال فجعل الناس يمرون به فيلعنونه فجاء إلى النبي صلى الله عليه وسلم فقال يا رسول الله ما لقيت من الناس قال وما لقيت قال يلعنوني قال فقد لعنك الله قبل الناس قال يا رسول الله فإني لا أعود وخرجه أبو داود بمعناه من حديث أبي هريرة ولم يذكر فيه فقد لعنك الله قبل الناس وخرج الخرائطي من حديث أم سلمة قالت دخلت شاة لجارة لنا فأخذت قرصة لنا فقمت إليها فأخذتها من بين لحييها فقال رسول الله صلى الله عليه وسلم إنه لا قليل من أذى الجار فأما إكرام الجار والإحسان إليه فمأمور به وقد قال الله تعالى واعبدوا الله ولا تشركوا به شيئا وبالوالدين إحسانا وبذي القربى واليتامى والمساكين والجار ذي القربى والجار الجنب والصاحب بالجنب وابن السبيل وما ملكت أيمانكم إن الله لا يحب من كان مختالا فخورا النساء فجمع الله تعالى في هذه الآية بين ذكر حقه على العبد وحقوق العباد على العباد أيضا وجعل العباد الذين أمر بالإحسان إليهم خمسة أنواع أحدها

ruh §419ruhArabic sense: اليتامى, اليتيم, يتامي, يتيم

وقد أخبرنا النبي صلى الله عليه و آله و سلم عن صاحب الشملة التي غلها من المغنم انها تشتعل نارا في قبره هذا وله فيها حق فكيف بمن ظلم غيره ما لا حق له فيه فعذاب القبر عن معاصي القلب و العين و الاذن و الفم و اللسان و البطن و الفرج و اليد و الرجل و البدن كله فالنمام و الكذاب و المغتاب و شاهد الزور و قاذف المحصن و الموضع في الفتنة و الداعي إلى البدعة و القائل على الله و رسوله مالا علم له به والمجازف في كلامه وآكل الربا آكل أموال اليتامى وآكل السحت من الرشوة و البرطيل و نحوهما وآكل مال أخيه المسلم بغير حق أو مال المعاهد و شارب المسكر وآكل لقمة الشجرة الملعونة والزاني واللوطي والسارق والخائن والغادر والمخادع والماكر وآخذ الربا ومعطيه وكاتبه وشاهداه والمحلل والمحلل له و المحتال على إسقاط فرائض الله وارتكاب محارمه ومؤذي المسلمين ومتتبع عوراتهم والحاكم بغير ما أنزل الله والمفتي بغير ما شرعه الله والمعين على الاثم و العدوان وقاتل النفس التي حرم الله والملحد في حرم الله والمعطل لحقائق أسماء الله وصفا

ighathat §1291ighathatArabic sense: اليتيم, يتيم

واحتل على مال اليتيم فإنه % رزق هنى من ضعيف الحال

mukhtasar-minhaj §2220mukhtasar-minhajArabic sense: اليتيم, يتيم

وثلاثة في البطن: شرب الخمر، وأكل مال اليتيم ظلما، وأكل الربا.

Research library

المكتبة البحثية851 works held

Peer-reviewed work held with its DOI and abstract, labelled with the study design its publication types report. None of it has been read or assessed, so nothing here may be cited as showing anything. Retracted work is held for the record but never listed; a review that a later version replaced is listed under its replacement and marked.

10.1016/j.amepre.2018.11.030American journal of preventive medicine (2019)MEDLINE-indexed journal, not yet read by us; matched on Adverse Childhood Experiences, Child Abuse, adverse childhood experiences

A Systematic Review of Trials to Improve Child Outcomes Associated With Adverse Childhood Experiences.: Context: The purpose of this systematic literature review was to summarize current evidence from RCTs for the efficacy of interventions involving pediatric health care to prevent poor outcomes associated with adverse childhood experiences measured in childhood (C-ACEs). Evidence acquisition: On January 18, 2018, investigators searched PubMed, PsycInfo, SocIndex, Web of Science, Cochrane, and reference lists for English language RCTs involving pediatric health care and published between January 1

10.1016/j.chiabu.2019.104127Child abuse & neglect (2019)MEDLINE-indexed journal, not yet read by us; matched on Adverse Childhood Experiences, Child Abuse, adverse childhood experiences

Adverse childhood experiences and associated health outcomes: A systematic review and meta-analysis.: Background: The Center for Disease Control (CDC) and Kaiser Permanente developed the Adverse Childhood Experiences (ACE) scale to identify negative experiences in childhood. The goal of this study is to systematically review outcomes associated with the ACEs in the CDC-Kaiser ACE scale to understand the diversity of outcomes associated with this scale. Methods: The authors conducted a search of English language articles published through September 30, 2016 using OVID Medline®; Ovid Medline® Dail

10.1016/j.chiabu.2020.104485Child abuse & neglect (2020)MEDLINE-indexed journal, not yet read by us; matched on Adverse Childhood Experiences, Child Abuse, adverse childhood experiences

Adverse Childhood Experiences and Executive Function Difficulties in Children: A Systematic Review.: Background: The relationship between adverse childhood experiences (ACEs) and detrimental mental health outcomes has been increasingly explored within scientific literature since the original ACE study was published by Felitti et al. (1998). Given that deficits in executive functions (EF) are prominent in most forms of psychopathology across the lifespan, there is utility in considering how ACEs relate to EF outcomes. Objective: To consolidate the research to date on the relationship between ACE

10.1016/j.neubiorev.2019.04.010Neuroscience and biobehavioral reviews (2019)MEDLINE-indexed journal, not yet read by us; matched on Adverse Childhood Experiences, Child Abuse, childhood maltreatment

Stress, epigenetics and depression: A systematic review.: Environmental stressors, such as childhood maltreatment, have been recognized to contribute to the development of depression. Growing evidence suggests that epigenetic changes are a key mechanism by which stressors interact with the genome leading to stable changes in DNA structure, gene expression, and behaviour. The current review aimed to evaluate the relationship between stress-associated epigenetic changes and depression. Human studies were identified via systematic searching of PubMed/Medl

10.1016/j.neubiorev.2022.104605Neuroscience and biobehavioral reviews (2022)MEDLINE-indexed journal, not yet read by us; matched on Adverse Childhood Experiences, Child Abuse, adverse childhood experiences

Adverse childhood experiences and allostatic load: A systematic review.: Adverse Childhood Experiences (ACEs) are stressful and/or traumatic experiences associated with an increased lifetime risk of negative health outcomes. The Allostatic Load (AL) is a measure of multisystem dysregulation, resulted by chronic stress. We systematically reviewed the English language literature on the association between ACEs and AL to identify the clinical risk profile, with the exclusion of reviews and preclinical studies. Searches covered the publication period up to the 1st of Feb

10.1186/s12889-020-08789-0BMC public health (2020)MEDLINE-indexed journal, not yet read by us; matched on Adverse Childhood Experiences, Child Abuse, adverse childhood experiences

Interventions to support people exposed to adverse childhood experiences: systematic review of systematic reviews.: Background: Adverse Childhood Experiences (ACEs) such as abuse, neglect or household adversity may have a range of serious negative impacts. There is a need to understand what interventions are effective to improve outcomes for people who have experienced ACEs. Methods: Systematic review of systematic reviews. We searched 18 database sources from 2007 to 2018 for systematic reviews of effectiveness data on people who experienced ACEs aged 3-18, on any intervention and any outcome except incidenc

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101 to 125 of 851
Dodge KA, Goodman WB, Bai Y, O'Donnell K, Murphy RA (2019)randomised controlled trialMEDLINE-indexed journal, not yet read by usJAMA network open42 citations

Effect of a Community Agency-Administered Nurse Home Visitation Program on Program Use and Maternal and Infant Health Outcomes: A Randomized Clinical Trial.

Importance: Postnatal home visitation to support parenting and infant healthy development is becoming increasingly common based on university efficacy studies, but effectiveness when disseminated by communities is not clear. Objective: To test implementation and impact of the Family Connects (FC) program when administered by a community agency. Design, setting, and participants: In this randomized clinical trial, births were randomly assigned to receive FC or treatment as usual. Independent evaluation was conducted through parent interviews and review of health and child protective services records. Interviewers were blind to the experimental condition of participants, and participants were blind about the purpose of the interview as an intervention evaluation. A total of 936 consecutive residential births at Duke University Hospital from January 1, 2014, through June 30, 2014, were incl

matched on Child Abuse (mesh)

Barlow J, Sembi S, Parsons H, Kim S, Petrou S, Harnett P, Dawe S (2019)randomised controlled trialMEDLINE-indexed journal, not yet read by usDrug and alcohol dependence33 citations

A randomized controlled trial and economic evaluation of the Parents Under Pressure program for parents in substance abuse treatment.

Background: There is growing interest in the provision of parenting support to substance misusing parents. Methods: This pragmatic, multi-center randomized controlled trial compared an intensive one-to-one parenting program (Parents under Pressure, PuP) with Treatment as Usual (TAU) in the UK. Parents were engaged in community-based substance misuse services and were primary caregivers of children less than 2.5 years of age. The primary outcome was child abuse potential, and secondary outcomes included measures of parental emotional regulation assessed at baseline, 6 and 12-months. A prospective economic evaluation was also conducted. Results: Of 127 eligible parents, 115 met the inclusion criteria, and subsequently parents were randomly assigned to receive PuP (n = 48) or TAU (n = 52). Child abuse potential was significantly improved in those receiving the PuP program while those in TAU

matched on Child Abuse (mesh)

Self-Brown S, Osborne MC, Boyd C, DeVeausse Brown N, Rostad W, Patterson A, Baker E, Thomas A, McAdam EM, Jackson M, Glasheen TL, Lai B (2018)randomised controlled trialMEDLINE-indexed journal, not yet read by usChild abuse & neglect8 citations

The impact of SafeCare® Dads to Kids program on father maltreatment risk and involvement: Outcomes and lessons learned from an efficacy trial.

Child Maltreatment (CM) is a public health problem, and experts recommend parent training programs as a prevention method. Few programs target fathers, even though male caregivers are involved as perpetrators in approximately 45% of substantiated CM cases. This study examines the efficacy of an adapted version of SafeCare (Dad2K) with marginalized fathers. Participants include a convenience sample of fathers with children ages 2-5 years. Fathers (n=99) were randomized to an 1) intervention group (SafeCare Dad2K) or to a 2) comparison group (receiving parenting information in the mail). Quantitative data were collected at baseline, post-intervention (7-weeks post-baseline), and 3-months post-intervention. Qualitative data (semi-structured interviews) were collected from 11 intervention father completers following the second quantitative data collection timepoint. Multi-level modeling resu

matched on Child Abuse (mesh)

Lachman JM, Cluver L, Ward CL, Hutchings J, Mlotshwa S, Wessels I, Gardner F (2017)randomised controlled trialMEDLINE-indexed journal, not yet read by usChild abuse & neglect56 citations

Randomized controlled trial of a parenting program to reduce the risk of child maltreatment in South Africa.

Parenting programs in high-income countries have been shown to reduce the risk of child maltreatment. However, there is limited evidence of their effectiveness in low- and middle-income countries. The objective of this study was to examine the initial effects of a parenting program in reducing the risk of child maltreatment in highly-deprived and vulnerable communities in Cape Town, South Africa. Low-income parents (N=68) with children aged three to eight years were randomly assigned to either a group-based parenting program or a wait-list control group. Observational and parent-report assessments were taken at baseline and at immediate post-test after the intervention was delivered. Primary outcomes were parent-report and observational assessments of harsh parenting, positive parenting, and child behavior problems. Secondary outcomes were parent-report assessments of parental depression

matched on Child Abuse (mesh)

Sanders MR, Dittman CK, Farruggia SP, Keown LJ (2014)randomised controlled trialMEDLINE-indexed journal, not yet read by usThe journal of primary prevention39 citations

A comparison of online versus workbook delivery of a self-help positive parenting program.

A noninferiority randomized trial design compared the efficacy of two self-help variants of the Triple P-Positive Parenting Program: an online version and a self-help workbook. We randomly assigned families of 193 children displaying early onset disruptive behavior difficulties to the online (N = 97) or workbook (N = 96) interventions. Parents completed questionnaire measures of child behavior, parenting, child maltreatment risk, personal adjustment and relationship quality at pre- and post-intervention and again at 6-month follow up. The short-term intervention effects of the Triple P Online program were not inferior to the workbook on the primary outcomes of disruptive child behavior and dysfunctional parenting as reported by both mothers and fathers. Both interventions were associated with significant and clinically meaningful declines from pre- to post-intervention in levels of disru

matched on Child Abuse (mesh)

Hurlburt MS, Nguyen K, Reid J, Webster-Stratton C, Zhang J (2013)randomised controlled trialMEDLINE-indexed journal, not yet read by usChild abuse & neglect31 citations

Efficacy of the Incredible Years group parent program with families in Head Start who self-reported a history of child maltreatment.

Objective: A prevention form of the Incredible Years (IY) parenting program was offered to parents who had children enrolled in Head Start, regardless of whether they reported having a history of child maltreatment. This study compared whether parenting practices and child behavioral outcomes differed in families who self reported a history of child maltreatment relative to families who did not. Methods: A site-randomized controlled trial of the IY parenting program was conducted in 64 classrooms in seven Head Start centers in Seattle, Washington. Families of 481 children took part in the study, with 335 in the IY condition and 146 in the control condition. Parenting practices and child behavior were measured by blinded raters through in-home observations and self-report questionnaires prior to the start of the IY program, in the spring after the IY program had concluded, and 12-18 month

matched on Child Abuse (mesh)

Jewkes RK, Dunkle K, Nduna M, Jama PN, Puren A (2010)randomised controlled trialMEDLINE-indexed journal, not yet read by usChild abuse & neglect177 citations

Associations between childhood adversity and depression, substance abuse and HIV and HSV2 incident infections in rural South African youth.

Objectives: To describe prevalence of childhood experiences of adversity in rural South African youth and their associations with health outcomes. Methods: We analyzed questionnaires and blood specimens collected during a baseline survey for a cluster randomized controlled trial of a behavioral intervention, and also tested blood HIV and herpes simplex type 2 virus at 12- and 24-month follow up; 1,367 male and 1,415 female volunteers were recruited from 70 rural villages. Results: Both women and men before 18 had experienced physical punishment (89.3% and 94.4%), physical hardship (65.8% and 46.8%), emotional abuse (54.7% and 56.4%), emotional neglect (41.6% and 39.6%), and sexual abuse (39.1% and 16.7%). Incident HIV infections were more common in women who experienced emotional abuse (IRR 1.96, 95% CI 1.25, 3.06, p=.003), sexual abuse (IRR 1.66 95% CI 1.04, 2.63, p=.03), and physical p

matched on Child Abuse (mesh)

McIntosh E, Barlow J, Davis H, Stewart-Brown S (2009)randomised controlled trialMEDLINE-indexed journal, not yet read by usJournal of public health (Oxford, England)31 citations

Economic evaluation of an intensive home visiting programme for vulnerable families: a cost-effectiveness analysis of a public health intervention.

Background: Recent reviews have shown that home visiting programmes that address parenting have the potential to improve long term health and social outcomes for children. However there are few studies exploring the cost-effectiveness of such interventions. The objective of this study was to evaluate the cost-effectiveness of an intensive home visiting programme directed at vulnerable families during the antenatal and postnatal periods. Methods: The design was an economic evaluation alongside a multicentre randomized controlled trial, in which 131 eligible women were randomly allocated to receive 18 months of intensive home visiting (n=67) or standard services (n=64). Due to the public health nature of the intervention a cost-effectiveness analysis was undertaken from a societal perspective. Results: The mean 'societal costs' in the control and intervention arms were 3874 pounds and 7120

matched on Child Abuse (mesh)

Calam R, Sanders MR, Miller C, Sadhnani V, Carmont SA (2008)randomised controlled trialMEDLINE-indexed journal, not yet read by usChild maltreatment45 citations

Can technology and the media help reduce dysfunctional parenting and increase engagement with preventative parenting interventions?

In an evaluation of the television series "Driving Mum and Dad Mad," 723 families participated and were randomly assigned to either a standard or technology enhanced viewing condition (included additional Web-support). Parents in both conditions reported significant improvements from pre- to postintervention in their child's behavior, dysfunctional parenting, parental anger, depression, and self-efficacy. Short-term improvements were maintained at 6-months follow-up. Regressions identified predictors of program outcomes and level of involvement. Parents who watched the entire series had more severe problems at preintervention and high sociodemographic risk than parents who did not watch the entire series. Few sociodemographic, child, or parent variables assessed at preintervention predicted program outcomes or program engagement, suggesting that a wide range of parents from diverse socio

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Barlow J, Davis H, McIntosh E, Jarrett P, Mockford C, Stewart-Brown S (2007)randomised controlled trialMEDLINE-indexed journal, not yet read by usArchives of disease in childhood89 citations

Role of home visiting in improving parenting and health in families at risk of abuse and neglect: results of a multicentre randomised controlled trial and economic evaluation.

Objectives: To evaluate the effectiveness and cost effectiveness of an intensive home visiting programme in improving outcomes for vulnerable families. Design: Multicentre randomised controlled trial in which eligible women were allocated to receive home visiting (n = 67) or standard services (n = 64). Incremental cost analysis. Setting: 40 general practitioner practices across 2 counties in the UK. Participants: 131 vulnerable pregnant women. Intervention: Selected health visitors were trained in the Family Partnership Model to provide a weekly home visiting service from 6 months antenatally to 12 months postnatally. Main outcome measures: Mother-child interaction, maternal psychological health attitudes and behaviour, infant functioning and development, and risk of neglect or abuse. Results: At 12 months, differences favouring the home-visited group were observed on an independent asse

matched on Child Abuse (mesh)

Sanders MR, Bor W, Morawska A (2007)randomised controlled trialMEDLINE-indexed journal, not yet read by usJournal of abnormal child psychology76 citations

Maintenance of treatment gains: a comparison of enhanced, standard, and self-directed Triple P-Positive Parenting Program.

This report describes the 3 year outcomes of three different variants of the Triple P-Positive Parenting Program, a behavioural family intervention. Families were randomly assigned to one of three intervention conditions or to a waitlist condition. At 1 year follow-up there were similar improvements on observational and self-report measures of preschooler disruptive behaviour for Enhanced, Standard and Self Directed variants of Triple P. At 3 year follow-up (completed by 139 families), each condition showed a similar level of maintenance of intervention effects. Approximately 2/3 of preschoolers who were clinically elevated on measures of disruptive behaviour at pre-intervention moved from the clinical to the non-clinical range. Across conditions, there was a comparable preventive effect for each intervention for these high risk children. The implications of the findings for the developm

matched on Child Abuse (mesh)

Appel K, Schwahn C, Mahler J, Schulz A, Spitzer C, Fenske K, Stender J, Barnow S, John U, Teumer A, Biffar R, Nauck M, Völzke H, Freyberger HJ, Grabe HJ (2011)randomised controlled trialMEDLINE-indexed journal, not yet read by usNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology180 citations

Moderation of adult depression by a polymorphism in the FKBP5 gene and childhood physical abuse in the general population.

Childhood maltreatment and depressive disorders have both been associated with a dysregulation of the hypothalamic-pituitary-adrenal axis. The FKBP5 gene codes for a co-chaperone regulating the glucocorticoid-receptor sensitivity. Previous evidence suggests that subjects carrying the TT genotype of the FKBP5 gene single-nucleotide polymorphism (SNP) rs1360780 have an increased susceptibility to adverse effects of experimental stress. We therefore tested the hypothesis of an interaction of childhood abuse with rs1360780 in predicting adult depression. In all, 2157 Caucasian subjects from the Study of Health in Pomerania (German general population) completed the Beck Depression Inventory (BDI-II) and Childhood Trauma Questionnaire. The DSM-IV diagnosis of major depressive disorder (MDD) was assessed by interview. Genotypes of rs1360780 were taken from the Affymetrix Human SNP Array 6.0. Si

matched on childhood maltreatment (text), Adult Survivors of Child Abuse (mesh), childhood trauma (text)

Barrett S, Muir C, Burns S, Adjei N, Forman J, Hackett S, Hirve R, Kaner E, Lynch R, Taylor-Robinson D, Wolfe I, McGovern R (2024)systematic reviewMEDLINE-indexed journal, not yet read by usTrauma, violence & abuse27 citations

Interventions to Reduce Parental Substance Use, Domestic Violence and Mental Health Problems, and Their Impacts Upon Children's Well-Being: A Systematic Review of Reviews and Evidence Mapping.

Introduction: Children exposed to parental intimate partner violence and abuse, mental illness, and substance use experience a range of problems which may persist into adulthood. These risks often co-occur and interact with structural factors such as poverty. Despite increasing evidence, it remains unclear how best to improve outcomes for children and families experiencing these adversities and address the complex issues they face. Aims and methods: Systematic review of systematic reviews. We searched international literature databases for systematic reviews, from inception to 2021, to provide an evidence overview of the range and effectiveness of interventions to support children and families where these parental risk factors had been identified. Results: Sixty-two systematic reviews were included. The majority (n = 59) focused on interventions designed to address single risk factors. R

matched on Child Abuse (keyword), Domestic Violence (mesh)

Nelson J, Klumparendt A, Doebler P, Ehring T (2017)meta-analysisMEDLINE-indexed journal, not yet read by usThe British journal of psychiatry : the journal of mental science580 citations

Childhood maltreatment and characteristics of adult depression: meta-analysis.

Background: Childhood maltreatment has been discussed as a risk factor for the development and maintenance of depression. Aims: To examine the relationship between childhood maltreatment and adult depression with regard to depression incidence, severity, age at onset, course of illness and treatment response. Method: We conducted meta-analyses of original articles reporting an association between childhood maltreatment and depression outcomes in adult populations. Results: In total, 184 studies met inclusion criteria. Nearly half of patients with depression reported a history of childhood maltreatment. Maltreated individuals were 2.66 (95% CI 2.38-2.98) to 3.73 (95% CI 2.88-4.83) times more likely to develop depression in adulthood, had an earlier depression onset and were twice as likely to develop chronic or treatment-resistant depression. Depression severity was most prominently linke

matched on childhood maltreatment (text), Adult Survivors of Child Abuse (mesh)

Infurna MR, Reichl C, Parzer P, Schimmenti A, Bifulco A, Kaess M (2016)meta-analysisMEDLINE-indexed journal, not yet read by usJournal of affective disorders340 citations

Associations between depression and specific childhood experiences of abuse and neglect: A meta-analysis.

Background: Research documents a strong relationship between childhood maltreatment and depression. However, only few studies have examined the specific effects of various types of childhood abuse/neglect on depression. This meta-analysis estimated the associations between depression and different types of childhood maltreatment (antipathy, neglect, physical abuse, sexual abuse, and psychological abuse) assessed with the same measure, the Childhood Experience of Care and Abuse (CECA) interview. Method: A systematic search in scientific databases included use of CECA interview and strict clinical assessment for major depression as criteria. Our meta-analysis utilized Cohen's d and relied on a random-effects model. Results: The literature search yielded 12 primary studies (reduced from 44), with a total of 4372 participants and 34 coefficients. Separate meta-analyses for each type of maltr

matched on childhood maltreatment (text), Adult Survivors of Child Abuse (mesh)

Agnew-Blais J, Danese A (2016)meta-analysisMEDLINE-indexed journal, not yet read by usThe lancet. Psychiatry278 citations

Childhood maltreatment and unfavourable clinical outcomes in bipolar disorder: a systematic review and meta-analysis.

Background: Bipolar disorder affects up to one in 25 individuals and identification of early risk indicators of negative outcomes could facilitate early detection of patients with greatest clinical needs and risk. We aimed to investigate the association between childhood maltreatment and key negative outcomes in patients with bipolar disorder. Methods: For this systematic review and meta-analysis we searched MEDLINE, PsycINFO, and Embase to identify articles published before Jan 1, 2015, examining the association of maltreatment (physical, sexual, or emotional abuse, neglect, or family conflict) before age 18 years with clinical features and course of illness in bipolar disorder. Data were extracted from published reports and any missing information was requested from investigators. We did 12 independent random-effects meta-analyses to quantify the associations between childhood maltreat

matched on childhood maltreatment (text), Adult Survivors of Child Abuse (mesh)

Russell D, Higgins D, Posso A (2020)systematic reviewMEDLINE-indexed journal, not yet read by usChild abuse & neglect46 citations

Preventing child sexual abuse: A systematic review of interventions and their efficacy in developing countries.

Background: Research on prevalence, risk factors, and prevention interventions for child sexual abuse has continued to focus on western and developed countries. Where country-level prevalence data or large-scale research exists, rates of child sexual abuse are consistently higher in developing and non-western countries than their western and developed counterparts. Objective: We systematically reviewed research on the nature of child sexual abuse interventions in developing countries, the settings and populations included to identify types of child sexual abuse prevention initiatives being implemented in developing countries and their effectiveness. Methods: Following PRISMA guidelines, we conducted a systematic search of six databases and identified eight studies to include in our analysis. Results: Most empirically evaluated interventions in developing countries have focused on prescho

matched on Child Abuse, Sexual (mesh)

Hailes HP, Yu R, Danese A, Fazel S (2019)systematic reviewMEDLINE-indexed journal, not yet read by usThe lancet. Psychiatry459 citations

Long-term outcomes of childhood sexual abuse: an umbrella review.

Background: Although many meta-analyses have examined the association between childhood sexual abuse and subsequent outcomes, the scope, validity, and quality of this evidence has not been comprehensively assessed. We aimed to systematically review existing meta-analyses on a wide range of long-term psychiatric, psychosocial, and physical health outcomes of childhood sexual abuse, and evaluate the quality of the literature. Methods: In this umbrella review, we searched four databases (PsycINFO, PubMed, Cumulative Index to Nursing and Allied Health Literature, and Global Health) from inception to Dec 31, 2018, to identify meta-analyses of observational studies that examined the association between childhood sexual abuse (before 18 years of age) and long-term consequences (after 18 years). We compared odds ratios (ORs) across different outcomes. We also examined measures of quality, includ

matched on Child Abuse, Sexual (mesh)

Lemaigre C, Taylor EP, Gittoes C (2017)systematic reviewMEDLINE-indexed journal, not yet read by usChild abuse & neglect90 citations

Barriers and facilitators to disclosing sexual abuse in childhood and adolescence: A systematic review.

Children and young people often choose not to disclose sexual abuse, thus preventing access to help and allowing perpetrators to continue undetected. A nuanced understanding of the barriers (and facilitators) to disclosure is therefore of great relevance to practitioners and researchers. The literature was systematically searched for studies related to child and adolescent disclosures of sexual abuse. Thirteen studies were reviewed and assessed for methodological quality. Results of the review illustrate the heterogeneous nature of these empirical studies. Findings demonstrate that young people face a number of different barriers such as limited support, perceived negative consequences and feelings of self-blame, shame and guilt, when choosing to disclose. Being asked or prompted, through provision of developmentally appropriate information, about sexual abuse facilitates disclosure. The

matched on Child Abuse, Sexual (mesh)

Godoy LC, Frankfurter C, Cooper M, Lay C, Maunder R, Farkouh ME (2021)reviewMEDLINE-indexed journal, not yet read by usJAMA cardiology173 citations

Association of Adverse Childhood Experiences With Cardiovascular Disease Later in Life: A Review.

Importance: Adverse childhood experiences (ACEs) are potentially harmful events that occur during childhood, spanning neglect, physical or sexual abuse, parental separation, or death, among others. At least 50% of the US adult population has experienced 1 or more ACEs before the age of 18 years, but in clinical practice, ACEs remain underrecognized. Adults who have experienced ACEs are at increased risk of developing health risk behaviors and, ultimately, cardiovascular disease (CVD). This review summarizes the evidence regarding the association of ACEs with CVD and the accompanying diagnostic and therapeutic approaches in the adult population. Observations: ACEs are commonly classified into 3 domains: abuse (psychological, physical, or sexual), household dysfunction (eg, substance use by household members, mental illness, parental separation), and neglect. These experiences elicit chron

matched on Adverse Childhood Experiences (mesh), adverse childhood experiences (text), Adult Survivors of Child Abuse (mesh), Adult Survivors of Child Adverse Events (mesh)

Briggs EC, Amaya-Jackson L, Putnam KT, Putnam FW (2021)reviewMEDLINE-indexed journal, not yet read by usThe American psychologist162 citations

All adverse childhood experiences are not equal: The contribution of synergy to adverse childhood experience scores.

The operationalization of childhood trauma and adversity into checklists commonly known as adverse childhood experiences, or ACEs, has become the most widely adopted methodology linking traumatic childhoods to adult outcomes. As the number of self-reported ACEs increase from 0 to 4 or more (4+), most studies find a roughly stepwise progression in risk for a wide range of negative medical and mental health outcomes. A score of 4+ ACEs, has become a de facto cutpoint, increasingly used clinically to define "high risk" status for a myriad of outcomes. Comparisons across studies using a 4+ cutpoint, however, find considerable heterogeneity in the degree of risk for the same outcomes. In addition to sample and methodological differences, certain pairs of ACEs comprising the cumulative ACE score interact synergistically to significantly increase the overall risk beyond the sum (or product) of

matched on Adverse Childhood Experiences (mesh), adverse childhood experiences (text), Adult Survivors of Child Adverse Events (mesh), childhood trauma (text)

Sun J, Patel F, Kirzner R, Newton-Famous N, Owens C, Welles SL, Chilton M, Chilton M (2016)randomised controlled trialMEDLINE-indexed journal, not yet read by usBMC public health11 citations

The Building Wealth and Health Network: methods and baseline characteristics from a randomized controlled trial for families with young children participating in temporary assistance for needy families (TANF).

Background: Families with children under age six participating in the Temporary Assistance for Needy Families Program (TANF) must participate in work-related activities for 20 h per week. However, due to financial hardship, poor health, and exposure to violence and adversity, families may experience great difficulty in reaching self-sufficiency. The purpose of this report is to describe study design and baseline findings of a trauma-informed financial empowerment and peer support intervention meant to mitigate these hardships. Methods: We conducted a randomized controlled trial of a 28-week intervention called Building Wealth and Health Network to improve financial security and maternal and child health among caregivers participating in TANF. Participants, recruited from County Assistance offices in Philadelphia, PA, were randomized into two intervention groups (partial and full) and one

matched on Adverse Childhood Experiences (keyword), adverse childhood experiences (text)

Butler M, Veltman E, Lyon D, Koye DN, Fitzpatrick P, Alisic E, Ney L, Goode A, Healy G, Hitchcock C (2025)clinical trialMEDLINE-indexed journal, not yet read by usBMJ open1 citations

Left Write Hook: trial protocol for a community-based type II hybrid effectiveness-implementation cluster randomised controlled trial of a boxing and writing-based intervention for adult survivors of child sexual abuse and gender-based violence in Australia.

Introduction: Sexual and gender-based violence can have long-term impacts on the physical and mental health of survivors, with demonstrated impairments to immune, endocrine and nervous systems, and increased risk of chronic conditions such as cardiovascular disease, depression and post-traumatic stress. Moreover, survivors commonly experience low self-efficacy and lack of perceived control over their lives. Creating space for survivors to feel empowered through a multidimensional approach to health promotion, considering both physical and psychological influences on health, is necessary to reduce chronic disease. Methods and analysis: In this type II hybrid effectiveness-implementation cluster randomised controlled trial, we evaluate a novel peer-led intervention that combines expressive writing and trauma-informed boxing, Left Write Hook, against trauma-informed boxing alone-an interven

matched on Child Abuse, Sexual (mesh), Adult Survivors of Child Abuse (mesh)

Adverse Childhood Experiences and Adult Mental Health Outcomes.

Importance: Exposure to adverse childhood experiences (ACEs) has consistently been associated with multiple negative mental health outcomes extending into adulthood. However, given that ACEs and psychiatric disorders cluster within families, it remains to be comprehensively assessed to what extent familial confounding contributes to associations between ACEs and clinically confirmed adult psychiatric disorders. Objective: To investigate whether associations between ACEs and adult mental health outcomes remain after adjusting for familial (genetic and environmental) confounding. Design, setting, and participants: This Swedish twin cohort study used a discordant twin pair design based on monozygotic (MZ) and dizygotic (DZ) twins. A total of 25 252 adult twins (aged 18-47 years) from the Swedish Twin Registry born between 1959 and 1998 were followed up from age 19 years until 2016, with a m

matched on Adverse Childhood Experiences (mesh), adverse childhood experiences (text)

Population vs Individual Prediction of Poor Health From Results of Adverse Childhood Experiences Screening.

Importance: Adverse childhood experiences (ACEs) are well-established risk factors for health problems in a population. However, it is not known whether screening for ACEs can accurately identify individuals who develop later health problems. Objective: To test the predictive accuracy of ACE screening for later health problems. Design, setting, and participants: This study comprised 2 birth cohorts: the Environmental Risk (E-Risk) Longitudinal Twin Study observed 2232 participants born during the period from 1994 to 1995 until they were aged 18 years (2012-2014); the Dunedin Multidisciplinary Health and Development Study observed 1037 participants born during the period from 1972 to 1973 until they were aged 45 years (2017-2019). Statistical analysis was performed from May 28, 2018, to July 29, 2020. Exposures: ACEs were measured prospectively in childhood through repeated interviews and

matched on Adverse Childhood Experiences (mesh), adverse childhood experiences (text)

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