Depression and low mood الاكتئاب

وَتَوَلَّىٰ عَنۡهُمۡ وَقَالَ يَٰٓأَسَفَىٰ عَلَىٰ يُوسُفَ وَٱبۡيَضَّتۡ عَيۡنَاهُ مِنَ ٱلۡحُزۡنِ فَهُوَ كَظِيمࣱ‏

and he turned away from them, saying, ‘Alas for Joseph!’ His eyes went white with grief and he was filled with sorrow

وَقَالُواْ ٱلۡحَمۡدُ لِلَّهِ ٱلَّذِيٓ أَذۡهَبَ عَنَّا ٱلۡحَزَنَۖ إِنَّ رَبَّنَا لَغَفُورࣱ شَكُورٌ

They will say, ‘Praise be to God, who has separated us from all sorrow! Our Lord is truly most forgiving, most appreciative

إِذۡ تَمۡشِيٓ أُخۡتُكَ فَتَقُولُ هَلۡ أَدُلُّكُمۡ عَلَىٰ مَن يَكۡفُلُهُۥۖ فَرَجَعۡنَٰكَ إِلَىٰٓ أُمِّكَ كَيۡ تَقَرَّ عَيۡنُهَا وَلَا تَحۡزَنَۚ وَقَتَلۡتَ نَفۡسࣰ ا فَنَجَّيۡنَٰكَ مِنَ ٱلۡغَمِّ وَفَتَنَّٰكَ فُتُونࣰ اۚ فَلَبِثۡتَ سِنِينَ فِيٓ أَهۡلِ مَدۡيَنَ ثُمَّ جِئۡتَ عَلَىٰ قَدَرࣲ يَٰمُوسَىٰ

Your sister went out, saying, “I will tell you someone who will nurse him,” then We returned you to your mother so that she could rejoice and not grieve. Later you killed a man, but We saved you from distress and tried you with other tests. You stayed among the people of Midian for years, then you came here as I ordained

أَهَٰٓؤُلَآءِ ٱلَّذِينَ أَقۡسَمۡتُمۡ لَا يَنَالُهُمُ ٱللَّهُ بِرَحۡمَةٍۚ ٱدۡخُلُواْ ٱلۡجَنَّةَ لَا خَوۡفٌ عَلَيۡكُمۡ وَلَآ أَنتُمۡ تَحۡزَنُونَ

And are these the people you swore God would never bless? [Now these people are being told], “Enter the Garden! No fear for you, nor shall you grieve.”’

۞إِذۡ تُصۡعِدُونَ وَلَا تَلۡوُۥنَ عَلَىٰٓ أَحَدࣲ وَٱلرَّسُولُ يَدۡعُوكُمۡ فِيٓ أُخۡرَىٰكُمۡ فَأَثَٰبَكُمۡ غَمَّۢا بِغَمࣲّ لِّكَيۡلَا تَحۡزَنُواْ عَلَىٰ مَا فَاتَكُمۡ وَلَا مَآ أَصَٰبَكُمۡۗ وَٱللَّهُ خَبِيرُۢ بِمَا تَعۡمَلُونَ

You fled without looking back while the Messenger was calling out to you from behind, and God rewarded you with sorrow for sorrow. [He has now forgiven you] so that you may not grieve for what you missed or for what happened to you. God is well aware of everything you do

ثُمَّ أَنزَلَ عَلَيۡكُم مِّنۢ بَعۡدِ ٱلۡغَمِّ أَمَنَةࣰ نُّعَاسࣰ ا يَغۡشَىٰ طَآئِفَةࣰ مِّنكُمۡۖ وَطَآئِفَةࣱ قَدۡ أَهَمَّتۡهُمۡ أَنفُسُهُمۡ يَظُنُّونَ بِٱللَّهِ غَيۡرَ ٱلۡحَقِّ ظَنَّ ٱلۡجَٰهِلِيَّةِۖ يَقُولُونَ هَل لَّنَا مِنَ ٱلۡأَمۡرِ مِن شَيۡءࣲۗ قُلۡ إِنَّ ٱلۡأَمۡرَ كُلَّهُۥ لِلَّهِۗ يُخۡفُونَ فِيٓ أَنفُسِهِم مَّا لَا يُبۡدُونَ لَكَۖ يَقُولُونَ لَوۡ كَانَ لَنَا مِنَ ٱلۡأَمۡرِ شَيۡءࣱ مَّا قُتِلۡنَا هَٰهُنَاۗ قُل لَّوۡ كُنتُمۡ فِي بُيُوتِكُمۡ لَبَرَزَ ٱلَّذِينَ كُتِبَ عَلَيۡهِمُ ٱلۡقَتۡلُ إِلَىٰ مَضَاجِعِهِمۡۖ وَلِيَبۡتَلِيَ ٱللَّهُ مَا فِي صُدُورِكُمۡ وَلِيُمَحِّصَ مَا فِي قُلُوبِكُمۡۚ وَٱللَّهُ عَلِيمُۢ بِذَاتِ ٱلصُّدُورِ

After sorrow, He caused calm to descend upon you, a sleep that overtook some of you. Another group, caring only for themselves, entertained false thoughts about God, thoughts more appropriate to pagan ignorance, and said, ‘Do we get a say in any of this?’ [Prophet], tell them, ‘Everything to do with this affair is in God’s hands.’ They conceal in their hearts things they will not reveal to you. They say, ‘If we had had our say in this, none of us would have been killed here.’ Tell them, ‘Even if you had resolved to stay at home, those who were destined to be killed would still have gone out to meet their deaths.’ God did this in order to test everything within you and in order to prove what is in your hearts. God knows your innermost thoughts very well

" Oh, my grief for Joseph! " And his eyes turned white because of the sorrow that he was suppressing. Revelation came from the Compeller of all engendered beings: " O Jacob! You grieve so much for him, but you do not grieve for what you are missing of Me by being busy with grief for him! " O Jacob, how long this sorrow and regret at separation from Joseph? How long will you suffer grief and coldly sigh? Do you not suffer grief that you are held back from Me while busy with him? " With two kiblahs you can't walk straight on the road of tawḤīd- either the Friend's approval, or your own caprice. [DS 488] " O Jacob! Be careful not to pass Joseph's name over your tongue any more, or I will remove your name from the register of the prophets. " The Pir of the Tariqah said, " Jacob's remembrance of Joseph was the seed of heartache, and Joseph's remembrance of Jacob was the seed of ease. Since Ja

And they shall say, “Praise belongs to God, who has put away sorrow from us.” O chevalier! The worth of the antidote is known by the snake-bitten, the worth of burning fire is known by the moth, the worth of Joseph's shirt is known by grieving Jacob. When someone is de- luded by his own safety and is given the antidote, how will he know its worth? If you want some- one to know the worth and gravity of the antidote, you need him whose spirit has reached his lips. A poor man is needed, broken-hearted, suffering pain, and burdened with grief to know the worth of this caress and the exaltedness of this address: “Praise belongs to God, who has put away sorrow from us.” Wait until tomorrow when that wounded-hearted poor man is placed on the throne of joy in the palisade of holiness while the serving boys and servants act like his slaves to spread the carpet before the seat of his good fortune.

And We tried thee with trials. In other words, “We cooked you well with trial until you became limpid and immaculate, then We took you totally to Ourselves, so that you would not belong to any other.” “O Moses, We took you to the oven of trial and put you into self-purification so that nothing would remain in your heart but My love and nothing on your tongue but My remembrance.” What were those trials and troubles that sat on his head? When he was first born he was born in secrecy, in a house without lamp, poor, without pleasures. His mother could not have a son be- cause of fear of Pharaoh, who was killing sons. She put him into the casket and threw it in the river. His first home was the river. His second home was the sword, the execution ground, and seeing the enemy. His third home was fear of the Egyptians, because he had killed one of them. Then he fled looking back at them, his hea

And he turned away from them no longer addressing them and said ‘Alas my grief for Joseph!’ yā asafā the final alif of asafā has taken the place of the possessive yā’ of genitive annexation sc. yā asafī in other words it means yā huznī ‘O my sorrow’. And his eyes turned white their dark colour was effaced and became white on account of his tears with grief for him such that he was filled with suppressed agony anguished and grief-stricken but not manifesting his grief.

And they will say ‘Praise be to God Who has removed all grief from us. Truly our Lord is Forgiving of sins Appreciative of obedience

Are these the ones of whom you swore that God would never grant them mercy?’ it has already been said to them ‘Enter Paradise; no fear shall come upon you nor shall you grieve’ a variant reading for udkhulū ‘enter’ imperative second person plural has the passive udkhilū ‘they have been admitted’ or dakhalū ‘they entered’; the negation clause ‘no fear shall come upon you nor shall you grieve’ is a circumstantial qualifier in other words they enter Paradise while this is being said to them.

حَدَّثَنَا هَدَّابُ بْنُ خَالِدٍ، حَدَّثَنَا حَمَّادُ بْنُ سَلَمَةَ، ح وَحَدَّثَنِي زُهَيْرُ بْنُ حَرْبٍ، حَدَّثَنَا مُعَاذُ بْنُ مُعَاذٍ الْعَنْبَرِيُّ، ح وَحَدَّثَنِي مُحَمَّدُ بْنُ عَبْدِ الأَعْلَى، حَدَّثَنَا الْمُعْتَمِرُ، ح وَحَدَّثَنَا إِسْحَاقُ، بْنُ إِبْرَاهِيمَ أَخْبَرَنَا جَرِيرٌ، كُلُّهُمْ عَنْ سُلَيْمَانَ التَّيْمِيِّ، ح وَحَدَّثَنَا أَبُو كَامِلٍ، فُضَيْلُ بْنُ حُسَيْنٍ - وَاللَّفْظُ لَهُ - حَدَّثَنَا يَزِيدُ بْنُ زُرَيْعٍ، حَدَّثَنَا التَّيْمِيُّ، عَنْ أَبِي عُثْمَانَ، عَنْ أُسَامَةَ بْنِ زَيْدٍ، قَالَ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏ "‏ قُمْتُ عَلَى بَابِ الْجَنَّةِ فَإِذَا عَامَّةُ مَنْ دَخَلَهَا الْمَسَاكِينُ وَإِذَا أَصْحَابُ الْجَدِّ مَحْبُوسُونَ إِلاَّ أَصْحَابَ النَّارِ فَقَدْ أُمِرَ بِهِمْ إِلَى النَّارِ وَقُمْتُ عَلَى بَابِ النَّارِ فَإِذَا عَامَّةُ مَنْ دَخَلَهَا النِّسَاءُ ‏"‏ ‏.‏

Usama b. Zaid reported that Allah's Messenger (way peace be upon him) said:I stood at the door of Paradise and I found that the overwhelming majority of those who entered therein was that of poor persons and the wealthy persons were detained to get into that. The denizens of Hell were commanded to get into Hell, and I stood upon the door of Fire and the majority amongst them who entered there was that of women

حَدَّثَنَا أَبُو كُرَيْبٍ، حَدَّثَنَا أَبُو أُسَامَةَ، عَنْ سَعِيدِ بْنِ أَبِي عَرُوبَةَ، سَمِعَ أَبَا رَجَاءٍ، عَنِ ابْنِ عَبَّاسٍ، قَالَ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم فَذَكَرَ مِثْلَهُ ‏.‏

This hadith is narrated likewise through another chain of transmitters

حَدَّثَنِي عَبْدُ اللَّهِ بْنُ مُحَمَّدٍ، حَدَّثَنَا عَبْدُ الْمَلِكِ بْنُ عَمْرٍو، حَدَّثَنَا زُهَيْرُ بْنُ مُحَمَّدٍ، عَنْ مُحَمَّدِ بْنِ عَمْرِو بْنِ حَلْحَلَةَ، عَنْ عَطَاءِ بْنِ يَسَارٍ، عَنْ أَبِي سَعِيدٍ الْخُدْرِيِّ، وَعَنْ أَبِي هُرَيْرَةَ، عَنِ النَّبِيِّ صلى الله عليه وسلم قَالَ ‏ "‏ مَا يُصِيبُ الْمُسْلِمَ مِنْ نَصَبٍ وَلاَ وَصَبٍ وَلاَ هَمٍّ وَلاَ حُزْنٍ وَلاَ أَذًى وَلاَ غَمٍّ حَتَّى الشَّوْكَةِ يُشَاكُهَا، إِلاَّ كَفَّرَ اللَّهُ بِهَا مِنْ خَطَايَاهُ ‏"‏‏.‏

Narrated Abu Sa`id Al-Khudri and Abu Huraira:The Prophet (ﷺ) said, "No fatigue, nor disease, nor sorrow, nor sadness, nor hurt, nor distress befalls a Muslim, even if it were the prick he receives from a thorn, but that Allah expiates some of his sins for that

حَدَّثَنَا إِبْرَاهِيمُ بْنُ الْمُنْذِرِ، قَالَ حَدَّثَنِي مُحَمَّدُ بْنُ فُلَيْحٍ، قَالَ حَدَّثَنِي أَبِي، عَنْ هِلاَلِ بْنِ عَلِيٍّ، مِنْ بَنِي عَامِرِ بْنِ لُؤَىٍّ عَنْ عَطَاءِ بْنِ يَسَارٍ، عَنْ أَبِي هُرَيْرَةَ ـ رضى الله عنه ـ قَالَ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏ "‏ مَثَلُ الْمُؤْمِنِ كَمَثَلِ الْخَامَةِ مِنَ الزَّرْعِ مِنْ حَيْثُ أَتَتْهَا الرِّيحُ كَفَأَتْهَا، فَإِذَا اعْتَدَلَتْ تَكَفَّأُ بِالْبَلاَءِ، وَالْفَاجِرُ كَالأَرْزَةِ صَمَّاءَ مُعْتَدِلَةً حَتَّى يَقْصِمَهَا اللَّهُ إِذَا شَاءَ ‏"‏‏.‏

Narrated Abu Huraira:Allah's Messenger (ﷺ) said, "The example of a believer is that of a fresh tender plant; from whatever direction the wind comes, it bends it, but when the wind becomes quiet, it becomes straight again. Similarly, a believer is afflicted with calamities (but he remains patient till Allah removes his difficulties.) And an impious wicked person is like a pine tree which keeps hard and straight till Allah cuts (breaks) it down when He wishes." (See Hadith No. 558, Vol)

حَدَّثَنَا عَبْدُ اللَّهِ بْنُ مَسْلَمَةَ بْنِ قَعْنَبٍ، حَدَّثَنَا سُلَيْمَانُ، - يَعْنِي ابْنَ بِلاَلٍ - عَنْ جَعْفَرٍ، عَنْ أَبِيهِ، عَنْ جَابِرِ بْنِ عَبْدِ اللَّهِ، أَنَّ رَسُولَ اللَّهِ صلى الله عليه وسلم مَرَّ بِالسُّوقِ دَاخِلاً مِنْ بَعْضِ الْعَالِيَةِ وَالنَّاسُ كَنَفَتَهُ فَمَرَّ بِجَدْىٍ أَسَكَّ مَيِّتٍ فَتَنَاوَلَهُ فَأَخَذَ بِأُذُنِهِ ثُمَّ قَالَ ‏"‏ أَيُّكُمْ يُحِبُّ أَنَّ هَذَا لَهُ بِدِرْهَمٍ ‏"‏ ‏.‏ فَقَالُوا مَا نُحِبُّ أَنَّهُ لَنَا بِشَىْءٍ وَمَا نَصْنَعُ بِهِ قَالَ ‏"‏ أَتُحِبُّونَ أَنَّهُ لَكُمْ ‏"‏ ‏.‏ قَالُوا وَاللَّهِ لَوْ كَانَ حَيًّا كَانَ عَيْبًا فِيهِ لأَنَّهُ أَسَكُّ فَكَيْفَ وَهُوَ مَيِّتٌ فَقَالَ ‏"‏ فَوَاللَّهِ لَلدُّنْيَا أَهْوَنُ عَلَى اللَّهِ مِنْ هَذَا عَلَيْكُمْ ‏"‏ ‏.‏

Jabir b. Abdullah reported that Allah's Apostle (ﷺ) happened to walk through the bazar coming from the side of 'Aliya and the people were on both his sides. There he found a dead lamb with very short ears. He took hold of his ear and said:Who amongst you would like to have this for a dirham? They said: We do not like to have it even for less than that as it is of no use to us. He said: Do you wish to have it (free of any cost)? They said: By Allah, even if it were alive (we would not have liked to possess that), for there is defect in it as its ear is very short; now it is dead also. Thereupon Allah's Messenger (ﷺ) said: By Allah, this world is more insignificant in the eye of Allah than it (this dead lamb) is in your eye

حَدَّثَنِي مُحَمَّدُ بْنُ الْمُثَنَّى الْعَنَزِيُّ، وَإِبْرَاهِيمُ بْنُ مُحَمَّدِ بْنِ عَرْعَرَةَ السَّامِيُّ، قَالاَ حَدَّثَنَا عَبْدُ الْوَهَّابِ، - يَعْنِيَانِ الثَّقَفِيَّ - عَنْ جَعْفَرٍ، عَنْ أَبِيهِ، عَنْ جَابِرٍ، عَنِ النَّبِيِّ صلى الله عليه وسلم ‏.‏ بِمِثْلِهِ غَيْرَ أَنَّ فِي حَدِيثِ الثَّقَفِيِّ فَلَوْ كَانَ حَيًّا كَانَ هَذَا السَّكَكُ بِهِ عَيْبًا ‏.‏

Jabir reported Allah's Apostle (ﷺ) narrating a hadith like this with a slight variation of wording

الرابع أصوات النياحة ونغماتها وتأثيرها في تهييج الحزن والبكاء وملازمة الكآبة والحزن قسمان محمود ومذموم

ومن له قوت يوم بيوم فهو في سلامة من جميع ذلك، وهذا سوى ما يقاسيه أرباب الأموال في الدنيا، من الخوف والحزن والهم والغم والتعب.

وأما الاكتئاب فهو افتعال من الكآبة وهي سوء الحال والانكسار من الحزن وقد كئب الرجل يكأب كأبة وكآبة كرأفة ورآفة ونشأة ونشاءة فهو كئيب وامرأة كئيبة وكأباء أيضا قال الراجز

| الفصل السابع عشر في اذكار الكرب والغم والحزن والهم

وكان بعض السلف يقول: الزهد في الدنيا يريح القلب والبدن، والرغبة فيها تكثر الهم والحزن. ### | 7 فصل في درجات الزهد وأقسامه

وقال ابن مسعود رضى الله عنه: إن الله تعالى بقسطه وعمله جعل الروح والفرح في اليقين والرضى، وجعل الهم والحزن في الشك والسخط.

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Identification of depression and anxiety during pregnancy: A systematic review and meta-analysis of test accuracy.: Introduction: Depression and anxiety are significant contributors to maternal perinatal morbidity and a range of negative child outcomes. This systematic review and meta-analysis aimed to review and assess the diagnostic test accuracy of selected screening tools (Edinburgh Postnatal Depression Scale [EPDS], EPDS-3A, Patient Health Questionnaire [PHQ-9]-, PHQ-2, Matthey Generic Mood Question [MGMQ], Generalized Anxiety Disorder scale [GAD-7], GAD-2, and the Whooley questions) used to identify wom

A cross-sectional study on factors influencing adolescent depression in the civil-conflict areas of Thailand.

BACKGROUND: Research on mental health problems among Muslim adolescents living in ongoing long-term civil conflict areas of Thailand is scarce. Thus, this study aims to measure the prevalence of depression and examine its influencing factors among adolescents in this type of area, Thailand’s three southernmost provinces. METHODS: This study employed 2021 household survey data collected in Thailand’s three southernmost provinces —Yala, Pattani, and Narathiwat. The studied samples included adolescents aged 13–17; 179 were males, and 208 were females. Depression was measured using the Center for Epidemiologic Studies of Depression Scale (CES-D), Thai Version, a 20-item and 4-point scale (0–3). The cut-off score for the risk of depression was 22. The binary logistic models were used to examine the effects of family- and mental health-related and other potential covariate factors on depressio…

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Near and far correlates of centenarian wellbeing.

Background and objectives: The current study's model, derived from The Developmental Model of Adaptation, investigated the associations of past influences, closeness to parents, and two assessments of current influences (religiosity and social support) on the wellbeing (depressive symptomatology and life satisfaction) of very old adults. Research design and methods: Cross-sectional data came from a convenience sample of 154 cognitively intact, community-dwelling, Oklahoma centenarians. SPSS was employed to assess descriptive statistics and associations among all constructs; Mplus was employed to test a mediational path model linking closeness to parents on life satisfaction and depressive symptomatology through religiosity and social support. Results: Social support was a current influence significantly associated with depressive symptomatology and life satisfaction, whereas religiosity …

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Examining the impact of racial discrimination on psychological distress and the mediation of forgiveness and self-esteem among latter-day saint Pacific Islander men in the United States.

There is a dearth of psychological research on the effects of racial discrimination on the mental health of Pacific Islander (PI) individuals in the United States in general, but more specially among Pacific Islander men. The objective of this study was to examine the intersections of racial discrimination, depression, anxiety, stress, anger, forgiveness, and self-esteem in a sample of 249 Latter-day Saint Pacific Islander men in the United States through an online Qualtrics survey. Specifically, this study also sought to examine the effects of racial discrimination and the indirect effects of forgiveness and self-esteem on anger and depression, anxiety, and stress among this Pacific Islander group. Elevated experiences of racial discrimination were linked to increased levels of anger and negative psychological outcomes, including depression, anxiety, and stress. Furthermore, experiences…

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Childhood Experiences of Identity-Related Discrimination and Associated Health Risks in the United States, 2021-2023.

Objective: To estimate the prevalence of parent-reported sexual orientation and gender identity (SOGI) discrimination among US children and adolescents and examine associated demographic, health, and adversity-related characteristics. Methods: We analyzed 2021 to 2023 National Survey of Children's Health (NSCH) data, a cross-sectional, caregiver-reported survey of U.S. children. We compared sociodemographic characteristics, health conditions, adverse childhood experiences (ACEs), co-occurring discrimination, and family context by SOGI discrimination status among children ages 6 to 17. Multivariable logistic regression identified characteristics independently associated with SOGI discrimination. Analyses incorporated survey weights and were stratified by age group. Results: Among 93,982 children ages 6 to 17, 2.2% were reported to have experienced SOGI-based discrimination. Relative to th…

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Dynamic interactions between physical activity, exercise adherence, and adverse psychological states in Chinese older adults: a cross-lagged network analysis.

Background: With the accelerating process of population ageing in China, negative emotional problems in older people have become increasingly prominent. Exploring the dynamic relationship between these emotions and physical activity, as well as exercise adherence, is of great significance for promoting the physical and mental health of older people. Methods: This study used a longitudinal design to conduct two follow-up surveys of 876 older adult individuals in China. A cross-lagged network analysis method was employed to examine the interactions between physical activity, exercise adherence, and adverse psychological states indicators (depression, anxiety, stress, loneliness, and sadness/anger rumination). Results: Cross-sectional network analysis showed that physical activity and exercise adherence maintained a stable relationship, and the network structure tended to become more concen…

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Association between Internet addiction and mental health problems among Chinese adolescents in the post-COVID-19 pandemic era: a propensity score matching study.

Background: Improving adolescent mental health is a priority for public health, with Internet addiction (IA) being notably linked to these problems. In the post-pandemic era, increased screen time and social isolation persist, albeit in a more normalized form, potentially continuing to affect adolescent mental health. The current study aims to examine the relationship between IA and mental health problems among Chinese adolescents in the post-COVID-19 pandemic era. Methods: A cross-sectional survey was conducted in two cities of Henan Province, China, between April and May 2023. A total of 8176 junior high school students were recruited from 6 schools using a stratified random cluster sampling method. The associations between IA and mental health problems were assessed using ordinary least squares model and propensity score matching, specifically employing 1:1 nearest neighbor matching, …

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Shortened telomere length, anxiety and psychological stress in systemic lupus erythematosus: a cross-sectional study.

Background: Oxidative stress and inflammation contribute to telomere length (TL) attrition, a hallmark of cellular senescence. Systemic lupus erythematosus (SLE) is associated with premature cellular aging; however, the clinical relevance of TL shortening remains unclear. This study aimed to compare the relative TL of SLE patients and healthy controls and explore its association with clinical features and disease burden. Methods: We conducted a cross-sectional study including adult SLE patients and age- and sex-matched healthy controls (18-60 years). Demographic and clinical data were collected, and TL was measured using quantitative polymerase chain reaction (qPCR). Among SLE patients, disease activity, cumulative damage, fatigue, depression, anxiety, stress, and physical activity were also assessed. Statistical analyses included descriptive statistics, Student's t-test or Mann-Whitney …

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Exploring Crocin's Role in Alleviating Memory Impairments and Depression-like Behaviors Induced by REM Sleep Deprivation, Focusing on BDNF and GSK-3β in Male Rats.

Rapid-eye movement sleep deprivation (REM SD) drastically alters behavioral functions and the mood state. Evidence demonstrates that the effects of REM SD on cognition and mood vary significantly based on the duration of deprivation. On the other hand, crocin (as a natural therapeutic compound found in Saffron) may be beneficial for the alleviation of SD effect. The present research aimed to explore the effects of REM SD of varying durations on behavioral functions and the expression levels of brain-derived neurotrophic factor (BDNF) and glycogen synthase kinase-3 beta (GSK-3β) in the prefrontal cortex. REM SD was conducted for 1, 5, or 10 days (6 h per day). Crocin was injected intraperitoneally at the dose of 50 mg/kg. The results showed that REM SD for 5- and 10-days increased locomotor activity and rearing, decreased pain threshold, and impaired passive avoidance memory performance. …

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Prevalence and correlates of anxiety and depression among ever-married reproductive-aged women in Bangladesh: national-level insights from the 2022 Bangladesh Demographic and Health Survey.

Background: The sound mental health of reproductive-aged women is crucial for overall maternal and child well-being. However, mental health aspects are historically overlooked in low- and lower-middle-income countries, including Bangladesh. National-level evidence on common mental disorders like anxiety and depression among reproductive-aged women is limited in Bangladesh. Therefore, this study aims to estimate the prevalence of anxiety and depression among ever-married reproductive-aged women in Bangladesh and examine their individual, marital, household, and contextual correlates. Methods: We used data from the Bangladesh Demographic and Health Survey 2022 that collected anxiety and depression data using GAD-7 and PHQ-9 modules, respectively. This study included a total of 19,987 ever-married women aged 15 to 49 years. We used a cluster-adjusted multivariable logistic regression model …

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A longitudinal, mixed methods study exploring the impact of civic engagement on psychosocial outcomes across early to mid adulthood.

Civic engagement during emerging adulthood plays a pivotal role in fostering a sense of community responsibility, providing a sense of societal purpose, and contributes to improved psychological adjustment. In this mixed-method longitudinal study, we further explored how civic engagement and psychological adjustment codevelop across emerging adulthood. Participants were drawn from The Future's Study, a Canadian longitudinal study capturing the transition to adulthood in Southwestern Ontario. The sample was predominantly White (81%), female identifying (71%), and largely affluent with 5.8% reporting lower than average family income. At ages 23, 26, and 32, participants completed measures of civic engagement, depression, and optimism; at age 26, participants had the opportunity to also complete a life story interview where they were asked to recount a key community scene from their lives a…

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Spiritual orientation and mental health: an SEM analysis of meaning and death attitudes as mediators in Turkish religious officials.

This study examines the relationships between spiritual orientation, meaning in life, attitudes towards death, and indicators of psychological health (depression, anxiety, and stress) among 348 Muslim religious officials in Turkey (28% female). Using structural equation modelling (SEM), the results showed that spiritual orientation directly and indirectly reduces psychological distress by enhancing personal meaning and fostering more accepting attitudes towards death. Results showed a moderate positive association between spiritual orientation and meaning in life, and weak but significant negative associations between meaning/attitudes towards death and psychological symptoms. As one of the first empirical studies to examine the mediating role of death attitudes in this population, the research highlights the theoretical relevance of existential frameworks such as logotherapy. The study …

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The relationship between lifestyle and the risk of depression among people living with someone who needs care: The Yamagata Cohort Study.

Aim: This study investigated the association between lifestyle habits and the risk of depression among people living with someone needing care in Japan. Methods: Data were collected from those who participated in the Yamagata Cohort Study; 11 019 participants aged 40 and above were considered. The primary endpoints were living with someone in need of care and depression risk, and individual factors related to these endpoints were examined. Unadjusted and multifactor-adjusted logistic regression analyses were conducted to examine the association between the risk of depression and personal factors among those living with someone needing care. Results: Of the participants, 942 (8.5%) were living with someone who needed care. The proportion of participants who were at risk for depression was significantly higher among those living with someone needing care; this group also had significantly …

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Associations between adherence to 24-hour movement guidelines with depression, anxiety, and loneliness among Chinese adolescents.

Purpose: While growing evidence suggests a link between meeting 24-hour movement guidelines and adolescent mental health, further investigation is needed to clarify this association. This cross-sectional study aimed to examine how adherence to single and combined 24-hour movement guidelines relates to depression, anxiety, and loneliness in adolescents, while exploring variations across sex and age. Methods: A total of 15,344 adolescents aged 10-18 years in Shanghai were selected using multi-stage stratified cluster random sampling in 2021. Data on movement behavior and mental health problems were collected through self-reported questionnaires. Logistic regression was used to assess the associations and stratified analyses were performed for sex and age groups. The STROBE checklist for observational research was adopted for reporting. Results: Only 2.7 % of our sample of Chinese adolescen…

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Brooding, reflection, and anger rumination in late life suicidal behavior.

Background: Current literature on age-specific risk factors for suicide in older adulthood is lacking. One risk factor for younger-life suicide, rumination, has not been extensively studied in older adults, but from prior research, may be more relevant to late-life vs. early life suicide. The current study investigated how multiple subtypes of rumination (i.e., brooding, reflection, and anger rumination) relate to suicidal ideation and recent suicidal behavior in late life. Methods: 378 participants aged 50-90 (mean age 63.4, SD 7.5) were recruited into a case-control study examining suicide in older adults. Participants were recruited into three groups: 1) depressed adults who had made a recent (past two years) suicide attempt, 2) those with depression but no suicide attempt, and 3) a healthy comparison group. Among depressed groups, we examined relationships between rumination types, t…

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Factors Contributing to Sexual Dysfunction in Female Schizophrenia Patients During Recovery: A Multifactorial Analysis.

Background: Female patients with schizophrenia may experience sexual dysfunction during the recovery period. Therefore, this study conducted a multifactorial analysis to identify factors impacting sexual dysfunction, aiming to aid in developing effective personalized intervention strategies and improving sexual function recovery in these patients. Methods: This retrospective study included the clinical data from 261 female schizophrenia patients treated at the First Affiliated Hospital of Jinzhou Medical University, diagnosed between February 2022 and March 2024. Based on the total Female Sexual Function Index (FSFI) scores, the patients were divided into the female sexual dysfunction (FSD) group (n = 69) and the non-female sexual dysfunction (non-FSD) group (n = 192). The clinical data of these patients were evaluated using the FSFI, Hamilton Depression Rating Scale (HAMD), Hamilton Anx…

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Adolescent screen time, anxiety/depression, and alcohol/e-cigarette use: evidence from the ABCD study.

BACKGROUND: Adolescents are spending more time on screens, which has been associated with anxiety, depression, and increased substance use, especially through social media. This study aimed to examine the prospective relationship between screen time and anxiety/depression and the moderating effect of alcohol/e-cigarette use. METHODS: Data were drawn from the Adolescent Brain and Cognitive Development (ABCD) study, with participants aged 9–10 at baseline (n = 9,474). This cohort study analyzed longitudinal data collected between 2016 and 2022. Parents completed the Child Behavior Checklist (CBCL), which assessed anxiety/depression at the year 3 follow-up. Group-based trajectory models identified screen time/social media patterns, and multivariable linear models examined anxiety/depression, including an interaction term for alcohol/e-cigarette use. RESULTS: Four groups of screen time were …

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The prevalence, characteristics, and psychological wellbeing of unpaid carers in the United Kingdom.

Background: This study sought to describe the characteristics of unpaid carers in the UK and assess levels of depression, anxiety, and mental health treatment seeking behaviours in this population. Methods: Data was derived from Wave 9 (n = 2790) of the COVID-19 Psychological Research Consortium (C19PRC) study, a longitudinal survey of adults in the UK. Logistic regression analyses were conducted to examine the characteristics of unpaid carers, association between caregiver status and psychological wellbeing, and caregiver-specific factors associated with risk of poor psychological wellbeing. Results: Approximately 15% (n = 417) of the sample reported providing unpaid care. Younger age, having three or more children in the household, and lower income were identified as significant correlates of caregiver status. Unpaid caregivers were at increased risk of depression or anxiety and mental…

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The impact of neighborhood environment on adolescent anxiety and depression: A moderated mediation model involving screen time and family function.

Objective: While the relationship between neighborhood environment and adolescent mental health is well-documented, few studies have examined the roles of screen time and family function in this association. This study aims to explore the "environment-behavior-health" pathway by investigating how neighborhood environment, screen time, and family function jointly influence adolescent anxiety and depression. Method: Data were drawn from a large-scale, two-wave survey of 5th-12th grade Chinese adolescents. A moderated mediation model was constructed to examine whether screen time mediates the relationship between neighborhood environment and adolescent anxiety and depression, and whether this indirect effect is moderated by family function. Results: The final sample included 8961 Chinese adolescents. Neighborhood environment was negatively associated with adolescents' screen time (b = -0.51…

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Does life get better after middle age? Cultural comparisons of trends and key predictors of life satisfaction across the lifespan.

Background: This study investigated 1) whether there are differences in the trajectory of life satisfaction (LS) across the lifespan between British and Indonesian adults, and 2) which factors are associated with LS overall, and according to culture and age. Methods: 1355 participants aged 18 to 91 were included: 649 British and 706 Indonesian. Participants completed an online questionnaire examining LS, quality of life (which included physical health, psychological wellbeing, social relationships, and environment), depression, anxiety, and religiosity. Data were examined looking at all participants within each culture and then by further separating each cultural group into three age groups (Young adults/YA (18-39), middle-aged/MA (40-59), older adults/OA (60+). Results: The trajectory of LS across the lifespan was U-shaped in British participants but followed an inverted U-shaped patter…

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The Mental Health and Well-Being of Adults With Intellectual Disabilities During the COVID-19 Pandemic Across the UK: A Four-Wave Longitudinal Analysis.

Background: Research concerning the impact of the COVID-19 pandemic on the mental health and well-being of adults with intellectual disabilities has been cross-sectional and small scale. We examined the trajectory of mental health and well-being across the pandemic period across the UK and the factors which predicted different mental health trajectories. Method: Adults with intellectual disabilities participated in co-designed structured interviews. Four waves of data were collected between December 2020 and late 2022. At Wave 1, 621 adults with intellectual disabilities participated, with 355 at Wave 4. Well-being, pandemic anxiety, depression, anxiety, anger and loneliness outcomes were measured. Latent class mixed modelling was used to identify subgroups and within-group trajectories. Results: Well-being and pandemic anxiety remained relatively stable across time, but levels of anger,…

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Perceived spousal similarity in outlook on life: implications for later-life well-being.

Objectives: People tend to choose marital partners who are similar to themselves, and spouses become increasingly similar in some respects due to shared life experiences. However, it is unknown whether spousal similarity contributes to the health of married people in later life. This study investigates whether and how spousal similarity in outlook on life is linked to later-life well-being. Methods: We used data from the Wisconsin Longitudinal Study, a long-running prospective study following graduates from Wisconsin high schools in 1957 and their selected siblings. We measured perceived spousal similarity in outlook on life at both the individual (i.e., self-evaluation) and couple (i.e., concordance/discordance in evaluations between spouses) levels when participants were, 65 years old, on average. Later-life well-being was measured by self-rated general health, functional limitations, …

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Cross-sectional and longitudinal associations of screen time with adolescent depression and anxiety.

Objective: The relationship between screen time and mental health in adolescents is debated in the scientific literature, with longitudinal studies lacking. This study examined the cross-sectional and longitudinal associations between screen time and depression and anxiety and the influence of maladaptive social media use and gender on these associations. Methods: We analysed a sample of 4058 adolescents (mean age = 13.9) recruited from 134 Australian schools as part of the Future Proofing Study, a 5-year prospective cohort study of adolescent mental health. Linear mixed models used Time 1 and Time 2 (12-month follow-up) data to examine cross-sectional and longitudinal associations of screen time with depression and anxiety and the influence of maladaptive social media use and gender. Results: Screen time was associated with mental health symptoms cross-sectionally, with each additional …

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Economic hardships during COVID-19 and maternal mental health: Combining samples with low incomes across three cities.

The COVID-19 pandemic increased maternal depression and anxiety, imperiling both mothers' own wellbeing and that of their children. To date, however, little is known about the extent to which these increases are attributable to economic hardships commonly experienced during the pandemic: income loss, job loss, and loss of health insurance. Few studies have examined the individual impacts of these hardships, and none have lasted beyond the first year of the pandemic. This study harmonizes data from six evaluations of pediatric-based parenting programs for women with young children and low incomes across three U.S. cities (N = 1,254). Low-income mothers are of special interest because their families have been disproportionately affected by economic shocks due to COVID-19, and mothers of young children have been more distressed than other mothers by COVID-19. The studies' combined window of…

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Spiritual Well-Being, Religiosity, Quality of Life, Distress, Social Support, Depression, and Anxiety Among English- and Arabic-Speaking Muslim Americans With Advanced Cancer: A Cross-Sectional Study.

Objective: To learn about spiritual and psychosocial palliative care needs of Muslim Americans with advanced cancer. Methods: A cross-sectional English/Arabic (patient preference) survey was conducted with 120 Muslim Americans with advanced cancer in New York City (2022-2023). Survey instruments included Functional Assessment of Cancer Therapy-General (FACT-G, quality of life), Hospital Anxiety and Depression Scale (HADS-2 subscales), Medical Outcomes Study (MOS-emotional, tangible, affectionate support, positive social interactions), Functional Assessment of Chronic Illness Therapy-Spiritual Wellbeing (FACIT-SP-spiritual wellbeing, Modified Duke Religious Index (DUREL-religious involvement), Distress Thermometer and Problems List. Results: Most participants were from South Asia (30.8%), Middle East/North Africa (30.8%), and US (21.7%). On average, patients had high quality of life (FACT…

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Ramadan fasting in adolescents with epilepsy: Seizure control and behavioral outcome.

Objectives: Data about the effect of Ramadan fasting on seizure control among adolescents with epilepsy (AWE) is scarce. Several psycho-behavioral problems have also been encountered in this teenage group. This study aimed to assess seizure frequency and behavioral outcomes after Ramadan fasting in a sample of AWE METHODS: In this prospective study, AWE who completed fasting during Ramadan 2024 were evaluated regarding the seizure frequency of each type during Shaban (the month immediately preceding Ramadan) and Ramadan. Three questionnaires were requested to be answered at the end of two months. They were Patient Health Questionnaire (PHQ-9), Modified Overt Aggression Scale (MOAS), and Barratt Impulsiveness Scale-Short Form (BIS-11-SF) for assessment of depression, aggression, and impulsivity, respectively RESULTS: One hundred twenty AWE, with a median age of 15 and IQR 13-17, were eval…

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