Not conceiving, and losing a pregnancy or a newborn.
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Verses named for this subject by hand come first. The rest are found by the subject’s own Arabic and English senses and are shown as lexical matches, not as anchors anyone has confirmed.
وَلَا يَزَالُ ٱلَّذِينَ كَفَرُواْ فِي مِرۡيَةࣲ مِّنۡهُ حَتَّىٰ تَأۡتِيَهُمُ ٱلسَّاعَةُ بَغۡتَةً أَوۡ يَأۡتِيَهُمۡ عَذَابُ يَوۡمٍ عَقِيمٍ
The disbelievers will remain in doubt about it until the Hour suddenly overpowers them or until torment descends on them on a Day devoid of all hope
أَوۡ يُزَوِّجُهُمۡ ذُكۡرَانࣰ ا وَإِنَٰثࣰ اۖ وَيَجۡعَلُ مَن يَشَآءُ عَقِيمًاۚ إِنَّهُۥ عَلِيمࣱ قَدِيرࣱ
male to whoever He will, or both male and female, and He makes whoever He will barren: He is all knowing and all powerful
فَأَقۡبَلَتِ ٱمۡرَأَتُهُۥ فِي صَرَّةࣲ فَصَكَّتۡ وَجۡهَهَا وَقَالَتۡ عَجُوزٌ عَقِيمࣱ
His wife then entered with a loud cry, struck her face, and said, ‘A barren old woman?’
وَفِي عَادٍ إِذۡ أَرۡسَلۡنَا عَلَيۡهِمُ ٱلرِّيحَ ٱلۡعَقِيمَ
There is another sign in the Ad: We sent the life-destroying wind against them
۞وَعِندَهُۥ مَفَاتِحُ ٱلۡغَيۡبِ لَا يَعۡلَمُهَآ إِلَّا هُوَۚ وَيَعۡلَمُ مَا فِي ٱلۡبَرِّ وَٱلۡبَحۡرِۚ وَمَا تَسۡقُطُ مِن وَرَقَةٍ إِلَّا يَعۡلَمُهَا وَلَا حَبَّةࣲ فِي ظُلُمَٰتِ ٱلۡأَرۡضِ وَلَا رَطۡبࣲ وَلَا يَابِسٍ إِلَّا فِي كِتَٰبࣲ مُّبِينࣲ
He has the keys to the unseen: no one knows them but Him. He knows all that is in the land and sea. No leaf falls without His knowledge, nor is there a single grain in the darkness of the earth, or anything, fresh or withered, that is not written in a clear Record
وَلَمَّا سُقِطَ فِيٓ أَيۡدِيهِمۡ وَرَأَوۡاْ أَنَّهُمۡ قَدۡ ضَلُّواْ قَالُواْ لَئِن لَّمۡ يَرۡحَمۡنَا رَبُّنَا وَيَغۡفِرۡ لَنَا لَنَكُونَنَّ مِنَ ٱلۡخَٰسِرِينَ
When, with much wringing of hands, they perceived that they were doing wrong, they said, ‘If our Lord does not have mercy and forgive us, we shall be the losers.’
Commentary on the verses above, at most two editions per verse.
And those who disbelieve will not cease to be in doubt of it that is the Qur’ān — because of what Satan had cast onto the tongue of the Prophet s and what had thereafter been nullified — until the Hour comes upon them unawares that is the Hour of their death or of resurrection comes upon them suddenly or there come upon them the chastisement of a day of desolation ‘aqīm namely the day of Badr which held nothing of good for disbelievers much like a sterile wind rīh ‘aqīm that bears no good; or it means the Day of Resurrection referred to as ‘desolate’ because thereafter there will be no more night.
Or He combines them that is to say or He makes them males and females; and He makes whomever He will infertile such that she is unable to conceive or he cannot have a child. Surely He is Knower of what He creates Powerful in bringing about whatever He will.
Then his wife Sarah came forward clamouring shouting fī sarratin is a circumstantial qualifier that is to say she came shouting and smote slapped her face and said ‘A barren old woman!’ who has never given birth to a child aged ninety-nine with Abraham being one hundred years old; or alternatively he was a hundred and twenty years old and she was ninety years old.
And those who disbelieved, will not cease to be in doubt about it until the Hour comes suddenly upon them, or there comes to them the torment of Yawm 'Aqim (55)The sovereignty on that Day will be that of Allah. He will judge between them. So those who believed and did righteous good deeds will be in Gardens of Delight (56)And those who disbelieved and denied Our Ayat, for them will be a humiliating torment (in Hell)(57) The Disbelievers will remain in Doubt and Confusion Allah tells us that the disbelievers will remain in doubt concerning this Qur'an. This was the view of Ibn Jurayj and was the view favored by Ibn Jarir. حَتَّىٰ تَأْتِيَهُمُ السَّاعَةُ بَغْتَةً (until the Hour comes suddenly upon them,) Mujahid said: "By surprise." Qatadah said: بَغْتَةً (suddenly) means, the command of Allah will catch the people unaware. Allah never seizes a people except when they are intoxicate
To Allah belongs the kingdom of the heavens and the earth. He creates what He wills. He bestows female upon whom He wills, and bestows male upon whom He wills (49)Or He bestows both males and females, and He renders barren whom He wills. Verily, He is the All-Knower and is Able (to do all things)(50) Allah tells us that He is the Creator, Sovereign and Controller of the heavens and the earth. Whatever he wills happens, and whatever He does not will does not happen. He gives to whomsoever He wills and withholds from whomsoever he wills; none can withhold what He gives, and none can give what He withholds, and He creates whatever He wills. يَهَبُ لِمَنْ يَشَاءُ إِنَاثًا (He bestows female upon whom He wills.) means, He gives them daughters only. Al-Baghawi said, "And among them (those who were given daughters only) was Lut, peace be upon him." وَيَهَبُ لِمَنْ يَشَاءُ الذُّكُورَ (and b
Has the story reached you, of the honored guests of Ibrahim (24)When they came in to him and said: "Salaman!" He answered: "Salamun" and said: "You are a people unknown to me. (25)Then he turned to his household, and brought out a roasted calf (26)And placed it before them (saying): "Will you not eat? (27)Then he conceived fear of them (when they ate not). They said: "Fear not." And they gave him glad tidings of a son having knowledge (28)Then his wife came forward with a loud voice; she smote her face, and said: "A barren old woman! (29)They said: "Even so says your Lord. Verily, He is the All-Wise, the All-Knower. (30) The Guests of the Prophet Ibrahim We mentioned this story before in Surah Hud and Al-Hijr. Allah said, هَلْ أَتَاكَ حَدِيثُ ضَيْفِ إِبْرَاهِيمَ الْمُكْرَمِينَ (Has the story reached you, of the honored guests of Ibrahim), whom Ibrahim honored and who, فَقَالُوا سَلَ
Sound narrations only, and never matched by text. A narration appears here because a compiler filed it under a chapter this subject maps to, or because someone read it and anchored it. Each row says which.
حَدَّثَنَا مَحْمُودُ بْنُ غَيْلاَنَ، حَدَّثَنَا أَبُو أَحْمَدَ الزُّبَيْرِيُّ، حَدَّثَنَا سُفْيَانُ، عَنِ الأَعْمَشِ، عَنْ عُمَارَةَ بْنِ عُمَيْرٍ، عَنْ عَبْدِ الرَّحْمَنِ بْنِ يَزِيدَ، عَنْ عَبْدِ اللَّهِ بْنِ مَسْعُودٍ، قَالَ خَرَجْنَا مَعَ النَّبِيِّ صلى الله عليه وسلم وَنَحْنُ شَبَابٌ لاَ نَقْدِرُ عَلَى شَيْءٍ فَقَالَ " يَا مَعْشَرَ الشَّبَابِ عَلَيْكُمْ بِالْبَاءَةِ فَإِنَّهُ أَغَضُّ لِلْبَصَرِ وَأَحْصَنُ لِلْفَرْجِ فَمَنْ لَمْ يَسْتَطِعْ مِنْكُمُ الْبَاءَةَ فَعَلَيْهِ بِالصَّوْمِ فَإِنَّ الصَّوْمَ لَهُ وِجَاءٌ " . قَالَ أَبُو عِيسَى هَذَا حَدِيثٌ حَسَنٌ صَحِيحٌ . حَدَّثَنَا الْحَسَنُ بْنُ عَلِيٍّ الْخَلاَّلُ، حَدَّثَنَا عَبْدُ اللَّهِ بْنُ نُمَيْرٍ، حَدَّثَنَا الأَعْمَشُ، عَنْ عُمَارَةَ، نَحْوَهُ . قَالَ أَبُو عِيسَى وَقَدْ رَوَى غَيْرُ، وَاحِدٍ، عَنِ الأَعْمَشِ، بِهَذَا الإِسْنَادِ مِثْلَ هَذَا . وَرَوَى أَبُو مُعَاوِيَةَ، وَالْمُحَارِبِيُّ، عَنِ الأَعْمَشِ، عَنْ إِبْرَاهِيمَ، عَنْ عَلْقَمَةَ، عَنْ عَبْدِ اللَّهِ، عَنِ النَّبِيِّ صلى الله عليه وسلم نَحْوَهُ . قَالَ أَبُو عِيسَى كِلاَهُمَا صَحِيحٌ .
Abdullah bin Mas'ud narrated:"We went with Allah's Messenger, while we were young men who had nothing. He said: 'O young men! You should marry, for indeed it helps in lowering the gaze and protecting the private parts. Whoever among you is not able to marry, then let him fast, for indeed fasting will diminish his sexual desire
حَدَّثَنَا أَبُو هِشَامٍ الرِّفَاعِيُّ، وَزَيْدُ بْنُ أَخْزَمَ الطَّائِيُّ، وَإِسْحَاقُ بْنُ إِبْرَاهِيمَ الْبَصْرِيُّ، قَالُوا حَدَّثَنَا مُعَاذُ بْنُ هِشَامٍ، عَنْ أَبِيهِ، عَنْ قَتَادَةَ، عَنِ الْحَسَنِ، عَنْ سَمُرَةَ، أَنَّ النَّبِيَّ صلى الله عليه وسلم نَهَى عَنِ التَّبَتُّلِ . قَالَ أَبُو عِيسَى وَزَادَ زَيْدُ بْنُ أَخْزَمَ فِي حَدِيثِهِ وَقَرَأَ قَتَادَةُ : (ولقدْ أَرْسَلْنا رُسُلاً مِنْ قَبْلِكَ وَجَعَلْنَا لَهُمْ أَزْوَاجًا وَذُرِّيَّةً ) . قَالَ وَفِي الْبَابِ عَنْ سَعْدٍ وَأَنَسِ بْنِ مَالِكٍ وَعَائِشَةَ وَابْنِ عَبَّاسٍ . قَالَ أَبُو عِيسَى حَدِيثُ سَمُرَةَ حَدِيثٌ حَسَنٌ غَرِيبٌ . وَرَوَى الأَشْعَثُ بْنُ عَبْدِ الْمَلِكِ هَذَا الْحَدِيثَ عَنِ الْحَسَنِ عَنْ سَعْدِ بْنِ هِشَامٍ عَنْ عَائِشَةَ عَنِ النَّبِيِّ صلى الله عليه وسلم نَحْوَهُ . وَيُقَالُ كِلاَ الْحَدِيثَيْنِ صَحِيحٌ .
Qatadah narrated from Al-Hasan, from Samurah that:The Prophet prohibited celibacy
وَحَدَّثَنَاهُ قُتَيْبَةُ بْنُ سَعِيدٍ، حَدَّثَنَا عَبْدُ الْعَزِيزِ يَعْنِي الدَّرَاوَرْدِيَّ، ح وَحَدَّثَنَا أَبُو بَكْرِ بْنُ أَبِي شَيْبَةَ حَدَّثَنَا خَالِدُ بْنُ مَخْلَدٍ، حَدَّثَنَا سُلَيْمَانُ بْنُ بِلاَلٍ، جَمِيعًا بِهَذَا الإِسْنَادِ .
This hadith has been narrated by Sulaiman b. Bilal with the same chain of transmitters
وَحَدَّثَنَا أَبُو بَكْرٍ، وَعُثْمَانُ، ابْنَا أَبِي شَيْبَةَ ح وَحَدَّثَنِي عَمْرٌو النَّاقِدُ، قَالُوا جَمِيعًا حَدَّثَنَا أَبُو خَالِدٍ الأَحْمَرُ، عَنْ يَزِيدَ بْنِ كَيْسَانَ، عَنْ أَبِي حَازِمٍ، عَنْ أَبِي هُرَيْرَةَ، قَالَ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم " لَقِّنُوا مَوْتَاكُمْ لاَ إِلَهَ إِلاَّ اللَّهُ " .
Abu Huraira reported Allah's Messenger (ﷺ) as saying:Exhort to recite" There is no god but Allah" to those of you who are dying
حَدَّثَنَا أَبُو بِشْرٍ، بَكْرُ بْنُ خَلَفٍ وَمُحَمَّدُ بْنُ بَشَّارٍ قَالاَ حَدَّثَنَا يَحْيَى بْنُ سَعِيدٍ، حَدَّثَنَا عَبْدُ الْحَمِيدِ بْنُ جَعْفَرٍ، عَنْ أَبِيهِ، عَنْ حَكِيمِ بْنِ أَفْلَحَ، عَنْ أَبِي مَسْعُودٍ، عَنِ النَّبِيِّ ـ صلى الله عليه وسلم ـ قَالَ " لِلْمُسْلِمِ عَلَى الْمُسْلِمِ أَرْبَعُ خِلاَلٍ يُشَمِّتُهُ إِذَا عَطَسَ وَيُجِيبُهُ إِذَا دَعَاهُ وَيَشْهَدُهُ إِذَا مَاتَ وَيَعُودُهُ إِذَا مَرِضَ " .
It was narrated from Abu Mas’ud that the Prophet (ﷺ) said:“The Muslim has four things due from the Muslim: He should answer [by saying Yarhamuk-Allah (may Allah have mercy on you)] to him if he sneezes (and says Al-Hamdulillah); he should accept his invitation if he invites him; he should attend his funeral if he dies; and he should visit him if he falls sick.”
حَدَّثَنَا أَبُو بَكْرِ بْنُ أَبِي شَيْبَةَ، حَدَّثَنَا مُحَمَّدُ بْنُ بِشْرٍ، عَنْ مُحَمَّدِ بْنِ عَمْرٍو، عَنْ أَبِي سَلَمَةَ، عَنْ أَبِي هُرَيْرَةَ، قَالَ قَالَ رَسُولُ اللَّهِ ـ صلى الله عليه وسلم ـ " خَمْسٌ مِنْ حَقِّ الْمُسْلِمِ عَلَى الْمُسْلِمِ رَدُّ التَّحِيَّةِ وَإِجَابَةُ الدَّعْوَةِ وَشُهُودُ الْجِنَازَةِ وَعِيَادَةُ الْمَرِيضِ وَتَشْمِيتُ الْعَاطِسِ إِذَا حَمِدَ اللَّهَ " .
It was narrated from Abu Hurairah that the Messenger of Allah (ﷺ) said:“Five are the rights of the Muslim: Returning his greeting, accepting his invitation; attending his funeral; visiting the sick; and answering (saying Yarhamuk-Allah) to the one who sneezes, if he praises Allah (says Al-Hamdu Lillah).”
Arabic originals, reached through the subject’s Arabic senses. Interpretive sources, never proof of a ruling.
وقال سري السقطى : من ادعى باطن علم ينقضه ظاهر حكم فهو غالط
وقال بشر ما سألت أحدا قط شيئا إلا سريا السقطى لأنه قد صح عندي زهده في الدنيا فهو يفرح بخروج الشيء من يده ويتبرم ببقائه عنده فأكون عونا له على ما يحب
وقال سرى السقطي رحمه الله آه على لقمة ليس على الله فيها تبعة ولا لمخلوق فيها منة
فيكره ذلك والسقط ينبغي أن يسمى
وكان سرى السقطي يقول للصوفية إذا خرج الشتاء فقد خرج أذار وأورقت الأشجار وطاب الإنتشار فانتشروا
وقال السري السقطي: إنى لأنظر كل يوم إلى أنفى مخافة أن يكون قد اسود وجهي.
Peer-reviewed work held with its DOI and abstract, labelled with the study design its publication types report. None of it has been read or assessed, so nothing here may be cited as showing anything. Retracted work is held for the record but never listed; a review that a later version replaced is listed under its replacement and marked.
A randomized clinical trial to determine optimal infertility treatment in older couples: the Forty and Over Treatment Trial (FORT-T).: Objective: To determine the optimal infertility therapy for women at the end of their reproductive potential. Design: Randomized clinical trial. Setting: Academic medical centers and private infertility center in a state with mandated insurance coverage. Patient(s): Couples with ≥ 6 months of unexplained infertility; female partner aged 38-42 years. Intervention(s): Randomized to treatment with two cycles of clomiphene citrate (CC) and intrauterine insemination (IUI), follicle stimulating hormon
The clinical effectiveness of the Mind/Body Program for Infertility on wellbeing and assisted reproduction outcomes: a randomized controlled trial in search for active ingredients.: Study question: Does the Mind/Body Program for Infertility (MBPI) perform better, due to certain distinctive elements, than a partly matched support group in improving the wellbeing and medically assisted reproduction (MAR) outcomes of women with elevated distress levels in a clinical setting? Summary answer: While robust enhancements occurred in the wellbeing overall, the cognitive behavioural and formalized stress management elements of the MBPI allowed a significantly stronger improvement in
Men's grief following pregnancy loss and neonatal loss: a systematic review and emerging theoretical model.: Background: Emotional distress following pregnancy loss and neonatal loss is common, with enduring grief occurring for many parents. However, little is known about men's grief, since the majority of existing literature and subsequent bereavement care guidelines have focused on women. To develop a comprehensive understanding of men's grief, this systematic review sought to summarise and appraise the literature focusing on men's grief following pregnancy loss and neonatal loss. Methods: A systemat
The effects of psychosocial interventions on the mental health, pregnancy rates, and marital function of infertile couples undergoing in vitro fertilization: a systematic review.: Purpose: The purpose of this study was to examine the effects of psychosocial interventions on the mental health, pregnancy rates, and marital function of infertile couples undergoing in vitro fertilization (IVF), as determined through RCT studies. Methods: Using the electronic databases PubMed, EMBase, Cochrane Library, CINAHL, PsycInfo, and CAJ, a systematic literature search was conducted in July 2015. MeSH terms, key words, and free words such as "infertility," "fertilization in vitro," "psy
Stress, distress and outcome of assisted reproductive technology (ART): a meta-analysis.: Background: A number of studies have investigated the relationship between psychological factors such as stress and distress (measured as anxiety and depression) and outcomes of assisted reproductive technology (ART). The results, however, are inconsistent, and the strength of any associations remains to be clarified. We conducted a systematic review and meta-analysis of the results of studies reporting on the associations between stress, anxiety, and depression and ART outcomes. Methods: Prospe
The impact of occupational shift work and working hours during pregnancy on health outcomes: a systematic review and meta-analysis.: Backgroud: An increasing number of original studies suggest that exposure to shift work and long working hours during pregnancy could be associated with the risk of adverse pregnancy outcomes, but the results remain conflicting and inconclusive. Objective: To examine the influences of shift work and longer working hours during pregnancy on maternal and fetal health outcomes. Data sources: Five electronic databases and 3 gray literature sources were searched up to March 15, 2019. Methods of study
Women's issues in epilepsy: Knowledge, awareness, and attitudes among a sample of the Bahraini population.
Background & objectives: A previous study conducted in Bahrain found a clear gender gap in men's willingness to marry women with epilepsy (WWE). Therefore, this study aimed to explore knowledge gaps in a sample of men living in Bahrain regarding issues related to females that might have influenced their attitudes toward WWE. Methods: An online self-reported questionnaire was used to collect data from males in the general population of Bahrain. The questions covered demographics, acceptance of marrying a WWE, the impact of epilepsy on sexual life, the risk of infertility, miscarriages, pregnancy outcomes, the risk of inheritance and birth defects in babies born to WWE, and parenting responsibilities. Results: A total of 1,054 males participated in the survey, with the sample predominantly young and highly educated. While most (82.4%) knew that epilepsy is caused by brain electrical dysfun…
matched on miscarriage (text), infertility (text)
Programmatic approaches to achieving equity for women in anesthesiology
Key points Women anesthesiologists can experience barriers and bias in the workplace, which varies in nature across their career and can negatively hinder professional development. Mitigation of these barriers and discrimination can be achieved through: (1) addressing individual bias, (2) closing the knowledge gap on the scope of bias, (3) deliberate representation, (4) strengthening professional networks, and (5) organized efforts to create policies that address gender inequity in the workplace. Women in anesthesiology is one example of several organized initiatives and programs that promote gender equity for women anesthesiologists of all identities. Introduction Women have long fought for equity in medicine and to be treated respectfully and professionally as physicians. One hundred seventy-five years ago, Elizabeth Blackwell was admitted to medical school as a joke, and since then, t…
matched on miscarriage (text), infertility (text)
Asherman's Syndrome: it may not be all our fault.
Asherman's Syndrome (AS) is an acquired condition defined by the presence of intrauterine adhesions (IUA) that cause symptoms such as menstrual abnormalities, pelvic pain, infertility, recurrent miscarriage, abnormal placentation and attendant psychological distress. Classically, AS is considered an iatrogenic disease triggered by trauma to the pregnant uterus. Different factors can cause the destruction of the endometrium, thus affecting the endometrial stem cell niche and creating IUAs. Curettage of the pregnant uterus appears to be the most common source of this destruction. Nevertheless, some AS cases have been associated with congenital uterine abnormalities and infections, and there are some idiopathic cases without any prior surgical procedures, suggesting a putative constitutional predisposition to IUA. Factors reported to cause AS share an underlying inflammatory mechanism leadi…
matched on miscarriage (text), infertility (text)
Trauma of Pregnancy Loss and Infertility for Mothers and Involuntarily Childless Women in the Contemporary United States.
Recent studies have repeatedly associated posttraumatic symptoms with women's experience of pregnancy loss. Using a nationally representative sample of American women (N = 2,894) from the National Survey of Fertility Barriers, the current study examines long-term psychological outcomes and reactions to pregnancy loss and infertility among mothers and involuntary childless women. In general, childless women who have experienced pregnancy loss or failure to conceive report the lowest life satisfaction and highest levels of depression despite a considerable period of time (seven years) since the loss or first year without a conception. However, women with the dual experience of pregnancy loss and involuntary childlessness report the most fertility-related distress. Results of the current study suggest that the "non-event" of involuntary childlessness may serve as an additional stressor in t…
matched on pregnancy loss (text), infertility (text)
Men and infertility in The Gambia: Limited biomedical knowledge and awareness discourage male involvement and exacerbate gender-based impacts of infertility.
Introduction: Infertility in Sub-Saharan Africa constitutes an important social and public health problem. Yet, there is a paucity of research on the experiences of men living with infertility, especially in West Africa. This study explored men's aetiological knowledge, views and experiences of infertility in the West Coast region of The Gambia, West Africa. Methodology: An explorative qualitative study was conducted among men living in the rural and urban communities of the West Coast region of The Gambia using in-depth interviews. Data collection and analysis were performed concurrently, and thematic data analysis was an iterative process carried out using NVivo 11 Analysis Software. Results: Gambian men had generally poor knowledge of infertility, allocating it to God, spiritual powers and bodily (biomedical) factors. While societal norms meant that infertility was generally attribute…
matched on Infertility, Male (mesh), infertility (text)
Psychological stress, stressful life events, male factor infertility, and testicular function: a cross-sectional study.
Objective: To assess the association between psychological stress and male factor infertility as well as testicular function (semen quality, serum reproductive hormones) and erectile dysfunction. Design: Cross-sectional study. Setting: University Hospital-based research center. Patients: Men with impaired semen quality were included from infertile couples, and men with naturally conceived pregnant partners were used as a reference population. Interventions: Participants completed a questionnaire on health and lifestyle, including a 14-item questionnaire about self-rated psychological stress symptoms and stressful life event (SLEs), had a physical examination performed, delivered a semen sample and had a blood sample drawn. Main outcomes: Differences in stress scores (calculated from self-reported stress symptoms) and SLEs between infertile and fertile men were assessed in crude and fully…
matched on Infertility, Male (mesh), infertility (text)
Relationship between natural and intrauterine insemination-assisted live births and the degree of sperm autoimmunisation.
Study question: What is the relationship between the degree of sperm autoimmunisation, as assessed by IgG-mixed antiglobulin reaction (MAR) test, and natural and intrauterine insemination (IUI)-assisted live births? Summary answer: Compared with a lower degree of positivity (50-99%), a 100%-positive MAR test was associated with a much lower occurrence of natural live births in infertile couples, who could be successfully treated with IUI, as first-line treatment. What is known already: The World Health Organization (WHO) has recommended screening for antisperm antibodies, through either the IgG-MAR test or an immunobead-binding test, as an integral part of semen analysis, with 50% antibody-coated motile spermatozoa considered to be the clinically relevant threshold. However, the predictive value of the degree of positivity of the MAR test above such a cut-off on the occurrence of natural…
matched on Infertility, Male (mesh), infertility (text)
Reproductive Health Literacy and Fertility Awareness Among Polish Female Students.
The falling fertility indicators and high prevalence of infertility in Poland make it important for people of reproductive age to have good knowledge of their own fertility in order to be able to take care of their reproductive health. This paper examines reproductive health literacy and fertility awareness among Polish female students. It can help identify gaps in reproductive health education in Poland. The study group included 456 women aged 18-29, who were students of 6 public universities located in Poznan, Poland. The method used was a survey using a self-developed questionnaire assessing the students' knowledge of female and male fertility-related physiology and fertility patterns. The respondents' knowledge was assessed on the basis of the percentage of correct answers. Regression analysis and univariate analysis of variance were used to explore relationships between the students…
matched on Fertility (mesh), infertility (text)
The Risk of Psychiatric Morbidity and Course of Distress in Males Undergoing Infertility Evaluation Is Affected by Their Factor of Infertility.
This panel study aimed to explore the effects of male, female, mixed or idiopathic factor of infertility on the course of clinical distress and possible psychiatric morbidity in involuntarily childless males undergoing fertility evaluation for the first time. A sample of 255 males completed the General Health Questionnaire-28 (GHQ-28) (a) at the baseline, before their initial fertility evaluation (T1); (b) before their second andrological appointment 2-3 months after diagnostic disclosure (T2); and (c) before subsequent treatment-related/follow-up appointments (T3, T4) to be screened for clinically significant distress and risk for psychiatric morbidity. Then they were dichotomized as non-cases and cases. The timing of psychological testing was strictly related to andrological appointments and medical procedures. The research demonstrated that the baseline prevalence of clinical distress…
matched on Infertility, Male (mesh), infertility (text)
Fertility-related knowledge and reproductive goals in childhood cancer survivors: short communication.
Study question: Do young adult survivors of childhood cancer know their fertility status, in the context of their parenthood goals and screening for gonadal functioning? Summary answer: While 80% of survivors (who were without children) wanted children in the future, most did not know their fertility status, and screening for gonadal functioning was underutilized. What is known already: Survivors of childhood cancer are at risk for infertility, but fertility counseling and assessment are underutilized. Separate studies indicated that survivors' fertility-related knowledge is poor and that they often wanted to have children. Yet, studies have not investigated the intersection of both issues, as well as potential distress if parenthood goals are not met. Study design, size, duration: Young adult male and female survivors of childhood cancer (N = 149) completed cross-sectional surveys, and …
matched on Fertility (mesh), infertility (text)
Is thyroid hormones evaluation of clinical value in the work-up of males of infertile couples?
Study question: Is thyroid hormones (TH) evaluation of clinical value in the work-up of males of infertile couples? Study answer: Our results suggest that TH evaluation is not mandatory in the work-up of male infertility. What is known already: A few previous studies performed on a limited series of subjects reported a negative impact of hyper- and hypo-thyroidism on semen volume, sperm concentration, progressive motility and normal morphology. No previous study has systematically evaluated associations between TH variation, semen parameters and ultrasound characteristics of the male genital tract. Study design, size and duration: Cross-sectional analysis of a consecutive series of 172 subjects seeking medical care for couple infertility from September 2010 to November 2014. Participants/materials, setting, methods: Of the entire cohort, 163 men (age 38.9 ± 8.0 years) free of genetic abn…
matched on Infertility, Male (mesh), infertility (text)
Semen quality impairment is associated with sexual dysfunction according to its severity.
Study question: Is sexual dysfunction associated with severity of semen quality impairment in men with couple infertility? Summary answer: In males of infertile couples the prevalence of erectile dysfunction (ED) increases as a function of semen quality impairment severity. What is known already: Infertile men are at a higher risk for sexual dysfunction, psychopathological and general health disorders. However, it has never been systematically investigated if these problems are associated with severity of semen quality impairment. Study design, size, duration: Cross-sectional analysis of a first-time evaluation of 448 males of infertile couples attending an outpatient clinic from September 2010 to November 2015. In addition, 74 age-matched healthy, fertile men from an ultrasound study on male fertility were studied for comparison. Participants/materials, setting, methods: All subjects un…
matched on Infertility, Male (mesh), infertility (text)
Current smoking is associated with lower seminal vesicles and ejaculate volume, despite higher testosterone levels, in male subjects of infertile couples.
Study question: What is the impact of smoking behaviour on seminal, hormonal and male genital tract ultrasound parameters in subjects seeking medical care for couple infertility? Study answer: In males of infertile couples, current smokers (CS), when compared with non-smokers, show lower ejaculate and ultrasound-derived seminal vesicles (SV) volume, despite higher testosterone levels. What is known already: Data on the effects of smoking on male fertility are conflicting. A correlation between smoking and reduced semen parameters has been reported, however, with a high heterogeneity among studies. An association between smoking behaviour and higher testosterone levels in men has been described in several, but not all, the previous studies. No study has systematically evaluated the impact of smoking on the male genital tract ultrasound characteristics. Study design, size and duration: Ret…
matched on Infertility, Male (mesh), infertility (text)
Effect of psychological stress on fertility hormones and seminal quality in male partners of infertile couples.
The present study evaluated the effect of psychological stress on male fertility hormones and seminal quality in male partner of infertile couples. Seventy male partners of infertile couples were evaluated for level of psychological stress using Hospital Anxiety and Depression Score (HADS) questionnaire, serum total testosterone, luteinising hormone (LH) and follicle-stimulating hormone (FSH) by electrochemiluminescence assay and serum GnRH by ELISA. Seminal analysis was performed as per WHO guideline. Nineteen (27%) of them had HADS anxiety and depression score ≥8 (abnormal HADS score). The persons having abnormal HADS had lower serum total testosterone, higher serum FSH and LH than those of persons having normal HADS. Serum total testosterone correlated negatively with HADS, but LH and FSH correlated positively. There was no change in GnRH with the change in stress or testosterone leve…
matched on Infertility, Male (mesh), infertility (text)
Seminal, ultrasound and psychobiological parameters correlate with metabolic syndrome in male members of infertile couples.
Metabolic syndrome (MetS) is a diagnostic category which identifies subjects at high risk for diabetes and cardiovascular diseases, erectile dysfunction (ED) and male hypogonadism. However, MetS impact on male infertility has been poorly studied. We systematically evaluated possible associations between MetS and clinical characteristics in men with couple infertility. Out of 367 consecutive subjects, 351 men without genetic abnormalities were studied. MetS was defined according to the International Diabetes Federation&American Heart Association/National Heart,Lung, and Blood Institute classification. All men underwent physical, hormonal, seminal and scrotal ultrasound evaluation. Erectile and ejaculatory functions were assessed by International Index of Erectile Function-15 erectile function domain (IIEF-15-EFD) and Premature Ejaculation Diagnostic Tool (PEDT), respectively, while psycho…
matched on Infertility, Male (mesh), infertility (text)
(Male) infertility: what does it mean to men? New evidence from quantitative and qualitative studies.
Scientific knowledge of the emotional repercussions of infertility on men remains limited and has only recently become the focus of social science research. Firstly, the current developments in research on the psychosocial impact of infertility on men through a search of the literature over the last 10 years are outlined in this paper. In the second section, issues raised in pretreatment counselling for men and their partner who consider donor insemination are described as this treatment typically raises many emotional issues. The results of more recent studies with sophisticated methodological design show that the emotional impact of infertility may be nearly balanced, suggesting that men do suffer as well and that they have to be addressed in infertility counselling too. The emotional and clinical aspects of donor insemination support the hypothesis that the emotional repercussions of …
matched on Infertility, Male (mesh), infertility (text)
Male coping with cancer-fertility issues: putting the 'social' into biopsychosocial approaches.
Biopsychosocial approaches in infertility and cancer services and research pay limited attention to 'social dimensions'. Additionally, existing cancer-related male infertility research is dominated by sperm banking studies even though fertility-related social concerns in the long term are reported to have an adverse effect on wellbeing. This paper considers whether social influences affected the fertility-related experiences of 28 men interviewed as part of a mixed-gender qualitative study of 'South Asian' and 'White' cancer survivors and their professional carers. Findings are reported under: managing stigma; sexuality and virility; ambiguity in fertile status; relationship to sperm; and meaning of fatherhood. Gender and other social influences were ambiguous, fluid and subtle--yet powerful. Combinations were neither standard nor static, indicating the dangers of practitioners stereotyp…
matched on Infertility, Male (mesh), infertility (text)
Male infertility and depression: a neglected problem in the Middle East.
Introduction: Little attention has been paid to the psychological status of infertile men from developing countries who have been traditionally stigmatized as feeble and ineffective. Aim: The aim of this study is to evaluate the prevalence of depression and its socio-demographic correlates in a sample of Iranian infertile men. Methods: One hundred and fourteen infertile men filled out the 21-item Beck Depression Inventory. Men who scored ≥ 17 were considered depressed and those with the score ≤ 16 were assumed to be nondepressed. Main outcome measures: (i) Comparison between depressed and non-depressed men regarding age, education level, economic status, ethnicity, age at time of marriage, duration, and type of infertility and regular cigarette smoking. (ii) Independent risk factors for depression. Results: The mean age of participants was 34.1 ± 7.1 years. The diagnosis of depression wa…
matched on Infertility, Male (mesh), infertility (text)
Workplace exposures and male infertility - a case-control study.
Objectives: This study examined the association between male infertility and certain occupational exposures. Material and methods: A case-control study was carried out from January 2008 to February 2009; on 255 infertile men and 267 fertile men controls. Occupational exposure to certain chemical, physical and psychological workplace hazards was assessed by self-report questionnaire. General and andrological examination was conducted for all participants, however, semen analysis was done only for the infertile men cases, because the fertile men controls refused to give semen samples. Results: After adjustment of confounders, the results revealed that the following workplace exposure factors significantly increased the risk of male infertility: solvents and painting materials (OR: 3.88, 95% CI: 1.50-10.03), lead (OR: 5.43, 95% CI: 1.28-23.13), VDTs and computers (OR: 8.01, 95% CI: 4.03-15.…
matched on Infertility, Male (mesh), infertility (text)
Treatment late effects in long-term survivors of pediatric sarcoma.
Purpose: To assess health and musculoskeletal function in survivors of pediatric sarcomas. Patients and methods: Thirty-two individuals treated for Ewing sarcoma family of tumors (ESFT), rhabdomyosarcoma (RMS), or non-rhabdomyosarcoma soft tissue sarcomas (NR-STS) with multi-modality therapy were enrolled on this cross-sectional study. Median age at the time of therapy was 15.4 years (range 7.1-34.2), median age at the time of analysis was 37.4 years (17.5-55.4), and median duration of time elapsed from completion of therapy was 17.3 years (2.9-32.6). Participants underwent assessments of musculoskeletal functioning, cardiac function, metabolic and lipid analyses, renal and gonadal function, and psychological evaluation. Results: This cohort of sarcoma survivors shows expected locoregional limitations in function of the area affected by sarcoma, and impaired global musculoskeletal functi…
matched on Infertility, Male (mesh), infertility (text)
Men's body mass index and infertility.
Background: In men, excess weight may be linked with altered testosterone, estradiol levels, poor semen quality and infertility. We investigated whether higher BMI among men is associated with infertility and if so, to what extent that effect might be mediated by altered sexual function. Methods: A retrospective cohort study of pregnancies from 1999 through 2005 based within the Norwegian Mother and Child Cohort Study (MoBa). Questionnaires assessed mother's and father's height and weight and time to pregnancy. Our sample comprises 26 303 planned pregnancies. Couples were considered infertile if they took >or=12 months to achieve pregnancy or received infertility treatment. Results: After adjusting for the woman's BMI, coital frequency and the ages and smoking habits of both partners, the odds ratio for infertility was 1.20 for overweight men [BMI 25-29.9; 95% confidence interval (CI) = …
matched on Infertility, Male (mesh), infertility (text)
Patterns of suffering and social interactions in infertile men: 12 months after unsuccessful treatment.
Research shows that men diagnosed with male factor infertility experience more suffering than men with infertility due to other causes, and that it is socially unfavourable to be diagnosed with male factor infertility resulting in secrecy surrounding diagnosis, sometimes to the point that women take the blame for the couples' infertility. We investigated mental and physical health, support, and psychological and social stress in men (N = 256) prior to and after 12 months of unsuccessful treatment according to their diagnosis: unexplained, female factor, male factor, or mixed. Results suggest that men do not differ by diagnosis on any of the variables tested. When treatment was not successful, all men showed increased suffering in the form of decreased mental health, increased physical stress reactions, decreased social support, and increased negative social stress over time. These findin…
matched on Infertility, Male (mesh), infertility (text)
Male infertility in Zimbabwe.
Objectives: There are very few studies on male infertility in sub-Saharan Africa. Sub-Saharan countries tend not to research male infertility because of economic reasons and, possibly, the psychological denial of the problem. Methods: The participants in the present study were 311 men with infertility problems who had been referred to the Andrology Clinic of the University of Zimbabwe. They were investigated by means of a clinical interview, a clinical examination, semen analysis and various endocrine tests. Results: It was found that 78% of the respondents had ever had a sexually transmitted disease. Most of the respondents reported that their infertility caused them stress and reported signs of mild depression. Most men mentioned also to seek treatment based on traditional methods. Men blamed that their wife was the reason of their childlessness. Conclusion: This study shows the import…
matched on Infertility, Male (mesh), infertility (text)
A new quality-of-life measure for men experiencing involuntary childlessness.
Background: Infertility may considerably reduce quality-of-life. Many of the existing generic quality-of-life measures, which often focus on physical impairments, do not represent the specific complaints of infertile patients. In this article, we report on the development and validation of the TLMK (Tübinger Lebensqualitätsfragebogen für Männer mit Kinderwunsch), an instrument for measuring quality-of-life in male patients with involuntary childlessness. Methods: The first version of the questionnaire, which consisted of 91 items, was administered to 275 men who attended andrology and gynaecology clinics for fertility evaluations. After the questionnaires were scored, item analysis and reduction, principal component analysis and internal consistency analyses were conducted. Results: The final version of the TLMK consists of 35 items in four scales and provides an internally consistent qu…
matched on Infertility, Male (mesh), infertility (text)
Fertility, gonadal and sexual function in survivors of testicular cancer.
Modern treatments cure most testicular cancer patients, so an important goal is to minimise toxicity. Fertility and sexual functioning are key issues for patients. We have evaluated these outcomes in a cross-sectional study of long-term survivors of testicular cancer. In total, 680 patients treated between 1982 and 1992 completed the EORTC Qly-C-30(qc30) questionnaire, the associated testicular cancer specific module and a general health and fertility questionnaire. Patients have been subdivided according to treatment received: orchidectomy either alone (surveillance, S n = 169), with chemotherapy (C, n = 272), radiotherapy (R, n = 158), or both chemotherapy and radiotherapy (C/RT n = 81). In the surveillance group, 6% of patients had an elevated LH, 41% an elevated FSH and 11% a low (< 10 nmol l(-1)) testosterone. Hormonal function deteriorated with additional treatment, but the effect …
matched on Infertility, Male (mesh), infertility (text)
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