Positive functioning as an outcome in its own right.
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3151 to 3175 of 6,178Webber MA (2010)MEDLINE-indexed journal, not yet read by usTransfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis4 citations Psychoneuroimmunological outcomes and quality of life.
According to the American Psychological Association the field of psychoneuroimmunology comprises a rapidly expanding body of knowledge that strongly suggests a reciprocal interaction between mind (cognition) and body. This body of knowledge indicates that cognitive events have somatic consequences that impact directly on the immune system and disease processes, which in turn lead to maladaptive cognitive processes. Disease sufferers' thought processes and perceived quality of life may thus have a direct bearing on their somatic functioning and disease process, and interventions at this level may have a material impact on their prognosis.
matched on Quality of Life (mesh), Mental Health (mesh), quality of life (text)
Feasibility and effectiveness of psychosocial resilience training: a pilot study of the READY program.
Despite many studies on the characteristics associated with resilience, there is little research on interventions to promote resilience in adults. The aims of this study were to gather preliminary information regarding the feasibility of implementing a group psychosocial resilience training program (REsilience and Activity for every DaY, READY) in a workplace setting, and to assess if program would potentially promote well-being. The program targets five protective factors identified from empirical evidence: Positive emotions, cognitive flexibility, social support, life meaning, and active coping. Resilience enhancement strategies reflect core acceptance and commitment therapy (ACT) processes and cognitive behavior therapy strategies. Sessions involve psychoeducation, discussions, experiential exercises, and home assignments. Sixteen participants completed 11 x two h group sessions over …
matched on Personal Satisfaction (mesh), Mental Health (mesh), well-being (text)
Nilsson ME, Maciejewski PK, Zhang B, Wright AA, Trice ED, Muriel AC, Friedlander RJ, Fasciano KM, Block SD, Prigerson HG (2009)MEDLINE-indexed journal, not yet read by usCancer116 citations Mental health, treatment preferences, advance care planning, location, and quality of death in advanced cancer patients with dependent children.
Background: Clinicians observe that advanced cancer patients with dependent children agonize over the impact their death will have on their children. The objective of this study was to determine empirically whether advanced cancer patients with and without dependent children differ in treatment preferences, mental health, and end-of-life (EOL) outcomes.
Methods: Coping with Cancer is a National Cancer Institute/National Institute of Mental Health-funded, multi-institutional, prospective cohort study of 668 patients with advanced cancer. Patients with and without dependent children were compared on rates of psychiatric disorders, advance care planning (ACP), EOL care, quality of their last week of life, and location of death.
Results: In adjusted analyses, patients with advanced cancer who had dependent children were more likely to meet panic disorder criteria (adjusted odds ratio [AOR], …
matched on Quality of Life (mesh), Mental Health (mesh), quality of life (text)
Social support network structure in older people: underlying dimensions and association with psychological and physical health.
Social networks have been associated with a wide variety of health outcomes in older people. We examined the dimensions underlying the Wenger social support network type assessment to identify dimensions associated with mental and physical health. We interviewed 1334 community-dwelling participants aged 65+. The Geriatric Mental State automated geriatric examination for computer-assisted taxonomy interview was used to rate psychiatric symptoms and quality of life. Cognitive impairment was defined as a score of <24 on the mini mental state examination. Clustering around latent variables identified two uncorrelated social support network domains: family (distance from and contact with relatives) and social engagement. Social engagement was associated with a lower age- and sex-adjusted prevalence of depression (odds ratio for a one-tertile increase 0.48), generalised anxiety disorder (OR 0.…
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The prevalence of dietary-related complementary and alternative therapies and their perceived usefulness among cancer patients.
Background: The present study aimed to directly assess and compare the usage, benefits and side-effects of dietary-related complementary and alternative medicine (CAM) use among adult cancer patients and non-cancer adults in Norwich, UK.
Methods: Self-administered questionnaires were completed by 98 cancer patients and 92 non-cancer adults to compare demographics, types of CAM usage with reasons, benefits, side-effects and CAM information sources. The groups were matched for gender, age, marital status, education and household income. The mean ages were 62.7 and 59.7 years, respectively, with slightly more female than male participants.
Results: CAM use was high in both groups (47% in cancer and 53% in non-cancer respondents, P > 0.05). The most widely-used diet-related CAM among both groups was the large intake of fruit, vegetables and juice, multivitamins, fish oils and glucosamine. Fi…
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Wright AA, Zhang B, Ray A, Mack JW, Trice E, Balboni T, Mitchell SL, Jackson VA, Block SD, Maciejewski PK, Prigerson HG (2008)MEDLINE-indexed journal, not yet read by usJAMA1,978 citations Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment.
Context: Talking about death can be difficult. Without evidence that end-of-life discussions improve patient outcomes, physicians must balance their desire to honor patient autonomy against a concern of inflicting psychological harm.
Objective: To determine whether end-of-life discussions with physicians are associated with fewer aggressive interventions.
Design, setting, and participants: A US multisite, prospective, longitudinal cohort study of patients with advanced cancer and their informal caregivers (n = 332 dyads), September 2002-February 2008. Patients were followed up from enrollment to death, a median of 4.4 months later. Bereaved caregivers' psychiatric illness and quality of life was assessed a median of 6.5 months later.
Main outcome measures: Aggressive medical care (eg, ventilation, resuscitation) and hospice in the final week of life. Secondary outcomes included patients'…
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Rosenbach C, Renneberg B (2008)MEDLINE-indexed journal, not yet read by usJournal of burn care & research : official publication of the American Burn Association47 citations Positive change after severe burn injuries.
Aims of the study were to examine positive change in people with severe burn injuries and to examine the impact of related constructs, demographic and medical variables on Post Traumatic Growth (PTG). A total of 149 participants who had been treated for a severe burn injury completed the posttraumatic growth inventory as well as other self-report inventories assessing coping, social support, quality of life, and mental distress. Similar to other populations who experienced trauma and adversity, burn survivors also report PTG. The strongest predictors for PTG were active coping and social support. Gender and age differences were found in the current study. Implications for further research and interventions facilitating PTG are discussed.
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Health-related quality of life in children and adolescents in Germany: results of the BELLA study.
Background: The self-perceived health or health-related quality of life of children and adolescents is increasingly recognised as a relevant outcome in medical practice and public health research. Identifying children and adolescents with particularly low health-related quality of life allows for an early detection of hidden morbidity and health care needs.
Objectives: The present study investigates health-related quality of life in children and adolescents in Germany.
Methods: In the Mental Health Module (BELLA study) of the German National Health Interview and Examination Survey for Children and Adolescents (KiGGS), the parents of 2,863 children and adolescents aged 7-17 years, and 1,700 children and adolescents aged 11-17 years completed the KINDL-R quality of life questionnaire.
Results: The reliability (Cronbach's alpha=0.86) and validity of the measurements using the parent-reporte…
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Quality of life before and after major lung resection for lung cancer: a prospective follow-up analysis.
Background: The objective of this study was to assess the preoperative and postoperative quality of life of candidates for major lung resection with lung cancer.
Methods: In all, 156 consecutive patients (144 lobectomies, 12 pneumonectomies) were prospectively assessed by means of the Short Form-36 Health Survey, version 2, preoperatively and 1 month and 3 months after operation. Serial quality of life scales were compared by repeated measures analysis of variance.
Results: In our series, most quality of life values were reduced compared with the general population. Compared with preoperative values, the physical composite scale was significantly reduced at 1 month (51 versus 45.1, p < 0.0001), and completely recovered at 3 months (51 versus 52.4, p = 0.2), whereas the mental composite scale remained unchanged. All correlation coefficients between these values and forced expiratory volum…
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Assessment of the age-specific disability weight of chronic schistosomiasis japonica.
Objective: To estimate the age-specific disability weight of chronic schistosomiasis japonica in China.
Methods: Between October 2004 and January 2005, residents from two schistosome-endemic counties were screened for Schistosoma japonicum infection using an enzyme-linked immunosorbent assay. Disability and morbidity were assessed in seropositive individuals using the European quality of life questionnaire with an additional cognitive dimension (known as the "EQ-5D plus") and ultrasonography. The age-specific disability weight of chronic schistosomiasis was estimated based on participants self-rated health scores on the visual analogue scale of the questionnaire; the relationships between health status, morbidity and disability weight were explored using multilevel regression models.
Findings: Of 2843 seropositive individuals, 1419 (49.9%) were classified as having chronic schistosomiasi…
matched on Quality of Life (mesh), Mental Health (mesh), quality of life (text)
Relationship between multimorbidity and health-related quality of life of patients in primary care.
Previous studies about the association of multimorbidity and the health-related quality of life (HRQOL) in primary-care patients are limited because of their reliance on simple counts of diseases from a limited list of diseases and their failure to assess the severity of disease. We evaluated the association while taking into account the severity of the medical conditions based on the Cumulative Illness Rating Scale (CIRS) score, and controlling for potential confounders (age, sex, household income, education, self-perception of economic status, number of people living in the same dwelling, and perceived social support). We randomly selected 238 patients to construct quintiles of increasing multimorbidity (CIRS). Patients completed the 36-item Medical Outcomes study questionnaire (SF-36) to evaluate their HRQOL. Applying bivariate and multivariate linear regression analyses, we used the …
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Moral Distress in the Time of COVID-19: Occupational Therapists' Perspectives.
The conditions of COVID-19 have caused moral distress in healthcare workers. Occupational therapists have had to adapt to these unknown times to best treat their clients. The purpose of this study was to explore the experience of moral distress in occupational therapists during the time of COVID-19. Eighteen occupational therapists were included who worked in a variety of settings. Investigators conducted semi-structured interviews to explore experience with moral distress (distress felt when confronting an ethical problem) during the time of COVID-19. The data were analyzed using a hermeneutical phenomenological approach to generate themes regarding the experience of moral distress. Investigators identified themes of occupational therapists' experiences during the COVID-19 pandemic. These themes included: Experiences of moral distress, capturing participants' encounters with morally dis…
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The association of social isolation and family structure on stroke-specific quality of life in a community-based study.
Purpose: Quality of Life (QOL) is a critical patient-centered outcome for individuals who have experienced stroke. This study examined the association of social isolation and family structure with Stroke-Specific QOL (SSQOL).
Methods: Participants were stroke survivors enrolled in the Brain Attack Surveillance in Corpus Christi (BASIC) study in Nueces County, Texas who completed 90-day post-stroke follow-up interviews between October 2019 and June 2023. Interviewers assessed QOL using the SSQOL scale, social isolation using the Patient-Reported Outcomes Measurement Information System (PROMIS) scale. Family structure was assessed based on marital status, family size, and whether adult children were living within 10 miles of the patient. Linear models were developed to analyze the relationship between social isolation and SSQOL with successive adjustment for demographic, clinical, socioeco…
matched on Quality of Life (mesh), Quality of Life (keyword), quality of life (text)
When hope is broken: A qualitative study of women's quality of life after late miscarriage or foetal loss.
Background: Late miscarriage and foetal loss are global health issues with enduring biopsychosocial consequences. Despite growing recognition, the long-term impact on women's quality of life remains underexplored.
Objective: To explore how late miscarriage and foetal loss affect women's quality of life, focusing on psychological, physical, social, and existential consequences, and to evaluate whether current healthcare support meets women's needs.
Methods: A qualitative study was conducted using semi-structured interviews with six women who had experienced late miscarriage or foetal loss. Data were analysed using systematic text condensation within a hermeneutic phenomenological framework.
Findings: Five themes captured the women's experiences: (1) Mental and physical consequences, including PTSD, anxiety, fatigue, and sleep disruption; (2) Social relationships and isolation, with loss o…
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Qualitative Findings From a Survey Measuring Informational Needs and Quality of Life of Women Living With Metastatic Breast Cancer.
Background: People living with metastatic breast cancer (MBC) may have different support requirements to those with early stage breast cancer (EBC). These differences can be substantial, particularly as care pathways and information are often designed around the latter. There is limited understanding of how these discrepancies impact patients with MBC.
Aims: In the LIMBER study (Living with Metastatic Breast Cancer), we explored the distinct and unmet needs of people living with MBC.
Methods: In collaboration with people living with MBC and healthcare professionals (HCPs), we developed an online survey comprising fixed and free text responses. Fixed responses and overall study demographics from the main LIMBER study have been published elsewhere. A framework analysis of the free text comments is reported here.
Results: The resulting thematic map has seven main themes - friends and family…
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Concealment of Parkinsons disease prevalence and impact on health and quality of life.
Concealment of diagnosis in chronic conditions has proven benefits as a coping strategy to avoid stigmatization and discrimination and allows people to be treated "normally" by society. However, concealment is related to negative health, physical, quality of life outcomes, exhaustion and loneliness. In addition, diagnosis concealment has a detrimental impact on self-management behaviors. In Parkinson's disease (PD), information regarding the aspects related to concealment is limited. A better understanding of the contributors and consequences of concealment in PD may facilitate the development of strategies to support patients who conceal. We conducted a cross-sectional study to explore concealment in PD by examining rates of diagnosis concealment and associations of concealment with socio-demographic factors, self-management behaviors, stigma, social support, and quality of life. The st…
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Menopausal wellbeing: navigating quality of life and osteoporosis risk.
Background: Multifaceted dimensions influence the quality of life among post-menopausal women. Osteoporosis, a condition characterized by fragile bones, poses a significant risk, potentially leading to fractures and decreased wellbeing. This study aims to assess the quality of life of postmenopausal women, its determinants, and also the risk of osteoporosis among them.
Methods: A cross-sectional study was done among 379 post-menopausal women residing in rural and urban areas of Ernakulam district, Kerala, India. They were selected by probability proportional to size sampling from 10 clusters. Quality of life was measured using MENQOL-I questionnaire and osteoporosis risk assessment was done using OSTA score.
Results: The study participants had a mean age of 60 years, (standard deviation of 6.83 years). On average, menopause occurred at 50.58 years (standard deviation of 4.28 years). The …
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Characteristics of children attending an autism specific early learning and care setting prior to and following introduction of the National Disability Insurance Scheme.
Background: The rollout of the National Disability Insurance Scheme (NDIS) has transformed the Australian funding landscape for individuals with disability and their families. This study examined whether the profiles of autistic children and their families accessing an early intervention (EI) setting have changed following its introduction.
Methods: The cognition and behavioural profiles of children funded under the NDIS (n = 58) were compared to children who had received block government funding (n = 58). Parental mental health and quality of life (QoL) outcomes were compared.
Results: Children presented with similar baseline cognition, functional abilities and autism behaviours at intake into EI irrespective of funding type. While parental QoL was similar across groups, parents funded by the NDIS reported significantly higher stress and depression levels.
Conclusions: The current findi…
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Evaluating quality of life changes in patients with cleft lip or palate: a mixed method pre- and postsurgical analysis in Karachi.
Background: Cleft lip and/or palate (CLP) is the most common orofacial congenital disability, presenting significant medical, psychological, and social challenges. In Pakistan, the incidence of CLP is high, estimated at one in 523 live births, but accurate data are lacking due to the absence of a birth registry. Early diagnosis and intervention are crucial for improving outcomes. This study evaluated the impact of CLP on patients' quality of life in Karachi, comparing pre- and post-surgical phases.
Methods: A sequential exploratory quantitative-qualitative mixed-methods study was conducted at two tertiary care hospitals in Karachi. In the quantitative phase, 280 patients with CLP, either awaiting or post-surgery, completed the Oral Health Impact Profile (OHIP-14) questionnaire to assess oral health-related quality of life (OHRQoL). Based on questionnaire responses, 30 participants were p…
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Ma BH, Chen G, Badji S, Petrie D (2024)MEDLINE-indexed journal, not yet read by usQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation4 citations Mapping the 12-item World Health Organization disability assessment schedule 2.0 (WHODAS 2.0) onto the assessment of quality of life (AQoL)-4D utilities.
Purpose: The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is a widely used disability-specific outcome measure. This study develops mapping algorithms to estimate Assessment of Quality of Life (AQoL)-4D utilities based on the WHODAS 2.0 responses to facilitate economic evaluation.
Methods: The study sample comprises people with disability or long-term conditions (n = 3376) from the 2007 Australian National Survey of Mental Health and Wellbeing. Traditional regression techniques (i.e., Ordinary Least Square regression, Robust MM regression, Generalised Linear Model and Betamix Regression) and machine learning techniques (i.e., Lasso regression, Boosted regression, Supported vector regression) were used. Five-fold internal cross-validation was performed. Model performance was assessed using a series of goodness-of-fit measures.
Results: The robust MM estimator …
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The use of prednisolone during Ramadan fasting in patients with adrenal insufficiency.
Objective: Once daily prednisolone taken at predawn has been proposed to be the glucocorticoid replacement of choice in patients with adrenal insufficiency (AI) who intend to fast for the month of Ramadan. However, the effects of prednisolone on metabolic parameters and quality of life during fasting for Ramadan are unknown.
Design, patients and measurements: Patients with AI on twice-daily hydrocortisone, who had low or moderate risk and intended to fast, were recruited. Patients were converted to prednisolone 5 mg once daily taken at sahur (predawn) and Ramadan education given. Weight, sleep duration, biochemical parameters and quality of life measures (SF-36 questionnaire) were analysed at the end of Ramadan and compared against baseline.
Results: Twenty patients (13 men) were recruited, with a mean age of 59.9 ± 15.0 years. All patients were on hydrocortisone 15 mg daily (in divided …
matched on Quality of Life (mesh), Quality of Life (keyword), quality of life (text)
A study evaluating quality of life and factors affecting it before, during and after menopause.
Objective: To determine if quality of life (QoL) changes before, during and after menopause and whether these changes are linked to symptoms, demographics, and/or lifestyle factors.
Methods: We undertook a cross-sectional online survey. We invited women aged between 35 and 60 years to complete the survey which included the Short-Form 36 (SF-36) generic quality of life measure, the menopause specific Utian-Quality of life (UQOL) measure, and questions about health and wellbeing, menopause symptoms and hormonal stage. The data were analysed with one-way ANOVA analysis and multivariate regression modelling.
Results: 279 women completed the survey. Most were aged between 51 and 55 years. In the unadjusted analysis there was a tendency for QoL to deteriorate from pre to peri to menopause and then increase slightly post menopause. This was however not significant in multivariate analysis. Mult…
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Giving and receiving thanks: a mixed methods pilot study of a gratitude intervention for palliative patients and their carers.
Background: Psychological research examining the nature and workings of gratitude has burgeoned over the past two decades. However, few studies have considered gratitude in the palliative care context. Based on an exploratory study which found that gratitude was correlated with better quality of life and less psychological distress in palliative patients, we designed and piloted a gratitude intervention where palliative patients and a carer of their choice wrote and shared a gratitude letter with each other. The aims of this study are to establish the feasibility and acceptability of our gratitude intervention and provide a preliminary assessment of its effects.
Methods: This pilot intervention study adopted a mixed-methods, concurrent nested, pre-post evaluation design. To assess the intervention's effects, we employed quantitative questionnaires on quality of life, quality of relations…
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Lim J (2023)MEDLINE-indexed journal, not yet read by usFrontiers in public health28 citations Effects of a cognitive-based intervention program using social robot PIO on cognitive function, depression, loneliness, and quality of life of older adults living alone.
Objective: Social robot interventions are being implemented to reduce cognitive decline, depression, and loneliness among older adults. However, the types, functions, and programs of effective social robots have not yet been confirmed. This study investigated whether a social robot intervention is effective in improving cognitive function, depression, loneliness, and quality of life in older adults living alone.
Methods: This study used a non-equivalent control group pre-test-post-test design. It was conducted twice a week, with each session lasting 50 mi; twelve sessions were conducted over 6 weeks. This study was conducted at three senior welfare centers in Korea. In each group, 10 or fewer participants used the PIO social robot. The total participants included 64 people in the experimental (n = 31) and control groups (n = 33), and consisted of older people over 65 years of age living …
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Hartmann-Boyce J, Cobiac LJ, Theodoulou A, Oke JL, Butler AR, Scarborough P, Bastounis A, Dunnigan A, Byadya R, Hobbs FDR, Sniehotta FF, Amies-Cull B, Aveyard P, Jebb SA (2023)MEDLINE-indexed journal, not yet read by usDiabetes, obesity & metabolism25 citations Weight regain after behavioural weight management programmes and its impact on quality of life and cost effectiveness: Evidence synthesis and health economic analyses.
Aims: We used data from a recent systematic review to investigate weight regain after behavioural weight management programmes (BWMPs, sometimes referred to as lifestyle modification programmes) and its impact on quality-of-life and cost-effectiveness.
Materials and methods: Trial registries, databases and forward-citation searching (latest search December 2019) were used to identify randomized trials of BWMPs in adults with overweight/obesity reporting outcomes at ≥12 months, and after programme end. Two independent reviewers screened records. One reviewer extracted data and a second checked them. The differences between intervention and control groups were synthesized using mixed-effect, meta-regression and time-to-event models. We examined associations between weight difference and difference in quality-of-life. Cost-effectiveness was estimated from a health sector perspective.
Result…
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