Positive functioning as an outcome in its own right.
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1851 to 1875 of 6,178The relationship between self-reported sexual satisfaction and general well-being in women.
Introduction: The extent to which low sexual function or sexual dissatisfaction in women impacts on well-being remains uncertain, yet this is a critical issue in the controversy as to the benefits of pharmacotherapy for women seeking treatment for female sexual dysfunction. Aim. To explore the relationship between well-being and self-perceived satisfaction with sexual function in women and to determine if there is an independent effect of menopausal status or age.
Design: A community-based cross-sectional study.
Patients: A total of 421 women, aged 18 to 65 years were recruited from the community. Women were required to self-identify at study outset as being either satisfied or dissatisfied with their sexual life and be premenopausal or postmenopausal.
Main outcome measures: Scores from the Psychological General Well-Being Index (PGWB), the Beck Depression Index (BDI) and a daily diary o…
matched on Personal Satisfaction (mesh), well-being (text)
Sehlen S, Vordermark D, Schäfer C, Herschbach P, Bayerl A, Pigorsch S, Rittweger J, Dormin C, Bölling T, Wypior HJ, Zehentmayr F, Schulze W, Geinitz H, DEGRO Quality of Life Work Group (2009)cohort or longitudinalMEDLINE-indexed journal, not yet read by usRadiation oncology (London, England)73 citations Job stress and job satisfaction of physicians, radiographers, nurses and physicists working in radiotherapy: a multicenter analysis by the DEGRO Quality of Life Work Group.
Background: Ongoing changes in cancer care cause an increase in the complexity of cases which is characterized by modern treatment techniques and a higher demand for patient information about the underlying disease and therapeutic options. At the same time, the restructuring of health services and reduced funding have led to the downsizing of hospital care services. These trends strongly influence the workplace environment and are a potential source of stress and burnout among professionals working in radiotherapy.
Methods and patients: A postal survey was sent to members of the workgroup "Quality of Life" which is part of DEGRO (German Society for Radiooncology). Thus far, 11 departments have answered the survey. 406 (76.1%) out of 534 cancer care workers (23% physicians, 35% radiographers, 31% nurses, 11% physicists) from 8 university hospitals and 3 general hospitals completed the FBA…
matched on Quality of Life (mesh), quality of life (text)
Wong IC, Asherson P, Bilbow A, Clifford S, Coghill D, DeSoysa R, Hollis C, McCarthy S, Murray M, Planner C, Potts L, Sayal K, Taylor E (2009)cohort or longitudinalMEDLINE-indexed journal, not yet read by usHealth technology assessment (Winchester, England)57 citations Cessation of attention deficit hyperactivity disorder drugs in the young (CADDY)--a pharmacoepidemiological and qualitative study.
Objectives: To estimate the prevalence of attention deficit hyperactivity disorder (ADHD) pharmacological treatment, and its demographic and clinical details, and to estimate the proportion of patients in the target group who stopped ADHD treatment and investigate possible factors for continuation or cessation of treatment.
Design: A pharmacoepidemiological study using an automated database and a qualititative study using patient interviews. Part 1 was a pharmacoepidemiological study that provided accurate data on use and cessation of ADHD drugs. Part 2 was an in-depth interview study to investigate the reasons, processes and outcomes of treatment cessation.
Setting: Part 1: primary care using the General Practice Research Database (GPRD). Part 2: secondary and tertiary care paediatric clinics, child and adolescent mental health and adult mental health clinics in London, Nottingham, Dund…
matched on Quality of Life (mesh), quality of life (text)
Aitken ME, McCarthy ML, Slomine BS, Ding R, Durbin DR, Jaffe KM, Paidas CN, Dorsch AM, Christensen JR, Mackenzie EJ, CHAT Study Group (2009)cohort or longitudinalMEDLINE-indexed journal, not yet read by usPediatrics125 citations Family burden after traumatic brain injury in children.
Objective: Traumatic brain injury has a substantial impact on caregivers. This study describes the burden experienced by caregivers of children with traumatic brain injury and examines the relationship between child functioning and family burden during the first year after injury.
Patients and methods: Children aged 5 to 15 years hospitalized for traumatic brain injury at 4 participating trauma centers were eligible. Caregivers completed baseline and 3- and 12-month telephone interviews measuring the child's health-related quality of life using the Pediatric Quality of Life Inventory. The emotional impact scale of the Child Health Questionnaire was used to identify caregivers with substantial distress, including general worry or interference with family routine. Caregiver perceptions of whether health care needs were met or unmet and days missed from work were also measured.
Results: A t…
matched on Quality of Life (mesh), quality of life (text)
Fear of recurrence and psychological distress in head and neck cancer patients and their carers.
Background: Fear of recurrence (FOR) has been increasingly recognised as an issue of significant burden for most cancer patients, and has been associated with psychological morbidity and reduced quality of life. More recently, the impact of recurrence fears has been indicated in the families of cancer patients. However, there has been a lack of prospective research.
Aim: To systematically examine distress and illness concerns among patient-carer dyads.
Methods: A multi-centre prospective study of head and neck cancer patients and their carers (patients, n=101; carers, n=101), surveyed at two time-points following diagnosis.
Results: Carers recorded higher recurrence concerns on average than the patient group (p<0.001). A predictive path model of patient and carer self-reports of distress and FORs was explored, with an excellent overall fit of the final model (chi(2)=15.4, df=12, p=0.22, …
matched on Quality of Life (mesh), quality of life (text)
Development and validation of the collaborative parent involvement scale for youths with type 1 diabetes.
Objective: To develop and test a youth-report measure of collaborative parent involvement in type 1 diabetes management.
Methods: Initial item development and testing were conducted with 81 youths; scale refinement and validation were conducted with 122 youths from four geographic regions. Descriptive statistics, Cronbach's alpha, and factor analyses were conducted to select items comprising the scale. Correlations with parenting style and parent diabetes responsibility were examined. Multiple regression analyses examining associations with quality of life, adherence, and glycemic control were conducted to assess concurrent validity.
Results: The measure demonstrated strong internal consistency. It was modestly associated with parenting style, but not with parent responsibility for diabetes management. A consistent pattern of associations with quality of life and adherence provide suppor…
matched on Quality of Life (mesh), quality of life (text)
Measuring offence-specific forgiveness in marriage: the Marital Offence-Specific Forgiveness Scale (MOFS).
Three studies involving 328 married couples were conducted to validate the Marital Offence-Specific Forgiveness Scale, a new measure assessing offence-specific forgiveness for marital transgressions. The studies examined the dimensionality; internal consistency; and discriminant, concurrent, and predictive validity of the new measure. The final scale comprised 2 distinct correlated dimensions, 1 positive (Benevolence) and 1 negative (Resentment-Avoidance), both of which had adequate internal consistency. The 2 dimensions discriminated marital forgiveness from affective empathy, rumination, attributions, and marital quality. Convergent validity of the new scale was indicated by significant relationships between its underlying dimensions and a host of predicted sociocognitive, relationship, trait, and well-being correlates of forgiveness. Providing evidence for predictive validity, forgive…
matched on Personal Satisfaction (mesh), well-being (text)
Factors related to perceived quality of life in patients with Alzheimer's disease: the patient's perception compared with that of caregivers.
Aims: To compare care recipient and caregiver perceptions of quality of life in patients (QoL-p) with Alzheimer's disease (AD). To identify associated factors, and the concordances-discrepancies.
Method: Cross-sectional analytic study of 236 patients and their carers using the Quality of Life in Alzheimer's Disease (QoL-AD) scale, socio-demographic data and clinical examination.
Results: Patients scored the QoL-AD more favourably than did caregivers (34.4 vs 31.3, p < 0.001). Cognitive deterioration did not affect the perception of QoL-AD (rho = -0.05, p = 0.394). The neuropsychiatric symptoms was associated with a negative perception of the QOL-AD in both patients (rho = -0.22, p < 0.01) and caregivers (rho = -0.47, p < 0.001). Greater functional autonomy was associated with a better perception of the QOL-AD in patients (rho = 0.17, p < 0.01) and even more so in caregivers (rho = 0.56, …
matched on Quality of Life (mesh), quality of life (text)
Alonso J, Buron A, Rojas-Farreras S, de Graaf R, Haro JM, de Girolamo G, Bruffaerts R, Kovess V, Matschinger H, Vilagut G, ESEMeD/MHEDEA 2000 Investigators (2009)cohort or longitudinalMEDLINE-indexed journal, not yet read by usJournal of affective disorders108 citations Perceived stigma among individuals with common mental disorders.
Background: Severe mental disorders are associated with social distance from the general population, but there is lack of data on the stigma reported by individuals with common mental disorders.
Aims: To identify the correlates and the impact of stigma among individuals with common mental disorders.
Methods: Cross-sectional, household interview survey of 8796 representing the non-institutionalized adults of Belgium, France, Germany, Italy, the Netherlands and Spain. Two perceived stigma questions (embarrassment and discrimination) were asked to respondents with significant disability. Health-related quality of life measured by the SF-12, work and activity limitation and social limitation were also assessed.
Results: Among the 815 participants with a 12-month mental disorder and significant disability, 14.8% had perceived stigma. Stigma was significantly associated with low education, bei…
matched on Quality of Life (mesh), quality of life (text)
Influence of gender, sexual orientation, and need on treatment utilization for substance use and mental disorders: findings from the California Quality of Life Survey.
Background: Prior research has shown a higher prevalence of substance use and mental disorders among sexual minorities, however, the influence of sexual orientation on treatment seeking has not been widely studied. We use a model of help-seeking for vulnerable populations to investigate factors related to treatment for alcohol or drug use disorders and mental health disorders, focusing on the contributions of gender, sexual orientation, and need.
Methods: Survey data were obtained from a population-based probability sample of California residents that oversampled for sexual minorities. Logistic regression was used to model the enabling, predisposing, and need-related factors associated with past-year mental health or substance abuse treatment utilization among adults aged 18-64 (N = 2,074).
Results: Compared with individuals without a diagnosed disorder, those with any disorder were more…
matched on Quality of Life (mesh), quality of life (text)
Symptom burden, depression, and spiritual well-being: a comparison of heart failure and advanced cancer patients.
Background: A lower proportion of patients with chronic heart failure receive palliative care compared to patients with advanced cancer.
Objective: We examined the relative need for palliative care in the two conditions by comparing symptom burden, psychological well-being, and spiritual well-being in heart failure and cancer patients.
Design: This was a cross-sectional study.
Participants: Sixty outpatients with symptomatic heart failure and 30 outpatients with advanced lung or pancreatic cancer.
Measurements: Symptom burden (Memorial Symptom Assessment Scale-Short Form), depression symptoms (Geriatric Depression Scale-Short Form), and spiritual well-being (Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being scale).
Main results: Overall, the heart failure patients and the cancer patients had similar numbers of physical symptoms (9.1 vs. 8.6, p = 0.79), depression scor…
matched on Quality of Life (mesh), well-being (text)
Quality of life of persons with lower-limb amputation during rehabilitation and at 3-month follow-up.
Objective: To describe and compare the quality of life (QOL) of persons with lower-limb amputation (LLA) at admission (T1), discharge (T2), and 3 months after rehabilitation discharge (T3) and to explore the relationships between QOL and demographic and clinical variables including body image.
Design: Longitudinal case series.
Setting: Inpatient rehabilitation facility.
Participants: Consecutive sample of 19 unilateral persons with LLA (14 men, mean age, 53.4+/-14.6y).
Intervention: Interdisciplinary rehabilitation.
Main outcome measures: Generic and specific QOL measures and perception of body image at T1, T2, and T3.
Results: Subjective QOL was relatively high at T1, T2, and T3 (0.87/2, 1.1/2, and 1.0/2, respectively) except for items related to physical functioning. There was no significant change over time for all but 1 QOL satisfaction measure (ability to go outside, P=.024). Prosth…
matched on Quality of Life (mesh), quality of life (text)
Impact of caregiving on health and quality of life: a comparative population-based study of caregivers for elderly persons and noncaregivers.
This study aims to investigate the impact of caregiving on the health status and quality of life (QOL) of primary informal caregivers (PCGs) of elderly care recipients in Hong Kong. A total of 246 PCGs and 492 matched noncaregiver (NCG) controls were identified in a population-based cross-sectional study through random telephone dialing. Their health status and QOL were assessed based on structured questionnaires and Short Form 36 (SF-36) Health Survey. Multiple conditional logistic regression analysis showed that compared with NCGs, PCGs had significantly increased risks for reporting worse health, more doctor visits, anxiety and depression, and weight loss. Female PCGs were more likely to report chronic diseases, symptoms, and insomnia. PCGs, particularly women, had significantly lower scores in all eight domains of SF-36 Health Survey. High caregiver burden score (Zarit Burden Scale) …
matched on Quality of Life (mesh), quality of life (text)
Lo M, Liu YH (2009)cohort or longitudinalMEDLINE-indexed journal, not yet read by usJournal of advanced nursing19 citations Quality of life among older grandparent caregivers: a pilot study.
Aim: This article is a report of a study conducted to compare quality of life and levels of depressive symptoms among older grandparent caregivers and non-caregivers in Taiwan.
Background: Little is known about grandparenthood in modern Chinese society. In particular, no research has been conducted to explore the consequences among Chinese grandparent caregivers of caring for grandchildren.
Methods: A cross-sectional comparative pilot study was conducted in 2007 in a city in Taiwan. A convenience sample of 45 grandparent caregivers and 48 grandparent non-caregivers was interviewed using a questionnaire including Taiwanese versions of the Short Form-36 Health Survey and Geriatric Depression Scale.
Results: No statistically significant differences in measures of quality of life or depression were found between the caregiver and non-caregiver groups. Physical health was poorer than mental h…
matched on Quality of Life (mesh), quality of life (text)
Hrabosky JI, Cash TF, Veale D, Neziroglu F, Soll EA, Garner DM, Strachan-Kinser M, Bakke B, Clauss LJ, Phillips KA (2009)cohort or longitudinalMEDLINE-indexed journal, not yet read by usBody image156 citations Multidimensional body image comparisons among patients with eating disorders, body dysmorphic disorder, and clinical controls: a multisite study.
Body image disturbance is considered a core characteristic of eating disorders and body dysmorphic disorder (BDD), however its definition has been unclear within the literature. This study examined the multidimensional nature of body image functioning among individuals with either anorexia nervosa (AN; n=35), bulimia nervosa (BN; n=26), or BDD (n=56), relative to female (n=34) and male (n=36) psychiatric controls. Participants were recruited from 10 treatment centers in the United States and England and completed psychometrically validated and standardized self-report measures of body image. Overall, the AN, BN, and BDD groups were characterized by significantly elevated disturbances in most body image dimensions relative to their gender-matched clinical controls. There was variability, however, in the comparisons among the three groups of interest, including foci of body dissatisfaction…
matched on Quality of Life (mesh), quality of life (text)
The symptom cluster of fatigue, pain, anxiety, and depression and the effect on the quality of life of women receiving treatment for breast cancer: a multicenter study.
Purpose/objectives: To examine the symptom cluster of fatigue, pain, anxiety, and depression and its effect on the quality of life (QOL) of women receiving chemotherapy or radiotherapy for breast cancer.
Design: Descriptive.
Setting: Oncology outpatient sections of four public hospitals in Hong Kong.
Sample: 215 ethnic Chinese women who were midway through treatment for breast cancer.
Methods: Chinese versions of the Brief Fatigue Inventory, Hospital Anxiety and Depression Scale, Brief Pain Inventory, Functional Assessment of Chronic Illness Therapy for Breast Cancer, and Medical Outcomes Study Social Support Survey were used. Spearman rho correlation and structural equation modeling were used to examine the relationships among the study variables.
Main research variables: Breast cancer, fatigue, pain, anxiety, depression, and QOL.
Findings: Most participants reported mild-to-moderate le…
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Self-identity after cancer: "survivor", "victim", "patient", and "person with cancer".
Background: Living through cancer often involves developing new identities which may strongly influence well-being and relationships with care providers, yet little is currently known about these post-cancer identities.
Objectives: To examine (1) the extent to which four post-cancer identities (patient, person who has had cancer, victim, and survivor) are adopted, (2) relations between each identity and involvement in cancer-related activities and mental and physical well-being, and (3) correlates of these identities.
Design: Cross-sectional questionnaire-based study.
Participants: 168 young to middle-aged adults who had previously experienced cancer.
Measurements: Cancer identifications, background variables, psychological functioning, cancer risk appraisals and coping, cancer-related activities, and mental and physical well-being.
Results: At least somewhat, 83% endorsed survivor ident…
matched on Quality of Life (mesh), well-being (text)
The effect of metabolic syndrome components on exercise performance in patients with intermittent claudication.
Purpose: To determine the effect of metabolic syndrome components on intermittent claudication, physical function, health-related quality of life, and peripheral circulation in patients with peripheral arterial disease (PAD), and to identify the metabolic syndrome components most predictive of each outcome measure.
Methods: Patients limited by intermittent claudication with three (n = 48), four (n = 45), or five (n = 40) components of metabolic syndrome were studied. Patients were assessed on PAD-specific measures consisting of ankle-brachial index (ABI), initial claudication distance, absolute claudication distance, physical function measures, health-related quality of life, and calf blood flow and transcutaneous oxygen tension responses after 3 minutes of vascular occlusion.
Results: Initial claudication distance (mean +/- SD) progressively declined (P = .019) in those with three (203 …
matched on Quality of Life (mesh), quality of life (text)
Refinement and psychometric evaluation of the impact of cancer scale.
Background: Instruments are needed to measure the influence of cancer on quality of life in the expanding population of long-term cancer survivors. We conducted refinement and psychometric evaluation of the Impact of Cancer (IOC) scale by use of data from a large sample of long-term breast cancer survivors and developed an instrument, the Impact of Cancer version 2 (IOCv2), to measure quality of life outcomes.
Methods: Questionnaires including 81 potential IOC scale items, the Center for Epidemiologic Studies-Depression (CES-D) scale, and the Breast Cancer Prevention Trial (BCPT) symptom scales, as well as demographic, treatment, and medical information, were completed by 1188 disease-free breast cancer survivors 5-10 years after diagnosis. We used exploratory factor analysis to identify scales and assessed reproducibility by split-sample cross-validation. Higher-order scales were extrac…
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Health-related quality of life among adults who experienced maltreatment during childhood.
Objectives: We sought to assess the difference in a preference-based measure of health among adults reporting maltreatment as a child versus those reporting no maltreatment.
Methods: Using data from a study of adults who reported adverse childhood experiences and current health status, we matched adults who reported childhood maltreatment (n = 2812) to those who reported no childhood maltreatment (n = 3356). Propensity score methods were used to compare the 2 groups. Health-related quality-of-life data (or "utilities") were imputed from the Medical Outcomes Study 36-Item Short Form Health Survey using the Short Form-6D preference-based scoring algorithm.
Results: The combined strata-level effects of maltreatment on Short Form-6D utility was a reduction of 0.028 per year (95% confidence interval=0.022, 0.034; P<.001). All utility losses for the childhood-maltreatment versus no-childhood-m…
matched on Quality of Life (mesh), quality of life (text)
Patient perspectives on the impact of fibromyalgia.
Objective: The objective of this study was to elicit and assess important symptom domains and the impact of fibromyalgia on patients' quality of life and functioning from a patient's perspective. The intention was to collect this information as part of an overall effort to overcome shortcomings of existing outcome measures in fibromyalgia.
Methods: This was a qualitative study in which six focus group sessions with 48 women diagnosed with fibromyalgia were conducted to elicit concepts and ideas to assess the impact of fibromyalgia on their lives.
Results: The focus groups conducted with fibromyalgia patients identified symptom domains that had the greatest impact on their quality of life including pain, sleep disturbance, fatigue, depression, anxiety, and cognitive impairment. Fibromyalgia had a substantial negative impact on social and occupational function. Patients reported disrupted …
matched on Quality of Life (mesh), quality of life (text)
Burden of premenstrual dysphoric disorder on health-related quality of life.
Objective: The purpose of this study was to document the burden of premenstrual dysphoric disorder (PMDD) on health-related quality of life (HRQoL) in comparison to the U.S. general population and specific chronic health conditions.
Methods: The disease burden that PMDD placed on HRQoL was estimated by comparing SF-12v2 scores between women who were identified as being at risk for PMDD with those observed in the general U.S. female population. Additional comparisons were made to several chronic health conditions. Regression methods were used to estimate SF-12v2 normative values from the general population sample and statistically adjust them to match age and the presence of disease comorbidity of the PMDD patient group. Significance tests were used to compare the means across samples.
Results: After adjusting for multiple comparisons, six SF-12v2 scales and two summary measures of PMDD w…
matched on Quality of Life (mesh), quality of life (text)
The impact of a long asylum procedure on quality of life, disability and physical health in Iraqi asylum seekers in the Netherlands.
Background: Refugees in western countries often face long juridical procedures before their requests for a resident permit is granted. The, still scanty, literature shows high prevalence rates of psychopathology among asylum seekers, but there has been little interest for other impaired dimensions of health. The present study is part of a community-based mental health survey among Iraqi asylum seekers in the Netherlands, conducted between November 2000 and September 2001, on the risks of a long asylum procedure.
Objectives: The objectives of this study were to explore quality of life (QoL), disability and physical health and their relationships with psychopathology and pre- and post-migration variables.
Method: Two groups of pre-stratified (length of asylum procedure), randomly selected Iraqi asylum seekers (N = 143 and N = 151), were interviewed with fully structured, culturally validat…
matched on Quality of Life (mesh), quality of life (text)
Burden, perceived health status, and mood among caregivers of Parkinson's disease patients.
The objective of this study is to describe the characteristics of the caregivers of patients with Parkinson's disease (PD) and to analyze the association between these characteristics and caregiver burden, perceived health and mood status, and identify their predictors. A multicenter, nationwide, observational, cross-sectional study that included 289 patient-caregiver pairs was conducted. Caregiver self-assessments were the Hospital Anxiety and Depression Scale (HADS), EuroQol (EQ), and Zarit Caregiver Burden Inventory (ZCBI). Most caregivers in the study were women aged 60 years or thereabouts. Over two thirds were gainfully employed or housewives, 75% were patients' spouses, and the majority (96.5%) had been permanently taking care of the patient for 6 +/- 5.4 years. Less than 5% of patients were in the most advanced stages of disease, and direct costs were 6,350 euros per patient per …
matched on Quality of Life (mesh), quality of life (text)
McCall-Hosenfeld JS, Jaramillo SA, Legault C, Freund KM, Cochrane BB, Manson JE, Wenger NK, Eaton CB, Rodriguez BL, McNeeley SG, Bonds D, Members of Women's Health Initiative-Observational Study (2008)cohort or longitudinalMEDLINE-indexed journal, not yet read by usJournal of general internal medicine50 citations Correlates of sexual satisfaction among sexually active postmenopausal women in the Women's Health Initiative-Observational Study.
Background: Satisfaction with sexual activity is important for health-related quality of life, but little is known about the sexual health of postmenopausal women.
Objective: Describe factors associated with sexual satisfaction among sexually active postmenopausal women.
Design: Cross-sectional analysis.
Participants: All members of the Women's Health Initiative-Observational Study (WHI-OS), ages 50-79, excluding women who did not respond to the sexual satisfaction question or reported no partnered sexual activity in the past year (N = 46,525).
Measurements:
Primary outcome: dichotomous response to the question, "How satisfied are you with your sexual activity (satisfied versus unsatisfied)?" Covariates included sociodemographic factors, measures of physical and mental health, and gynecological variables, medications, and health behaviors related to female sexual health.
Results: Of the …
matched on Quality of Life (mesh), quality of life (text)