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Qurʾān

القرآن6 shown

Verses named for this subject by hand come first. The rest are found by the subject’s own Arabic and English senses and are shown as lexical matches, not as anchors anyone has confirmed.

Qur'ān 48:18Arabic sense: السكينة, سكينه | English sense: tranquillity

۞لَّقَدۡ رَضِيَ ٱللَّهُ عَنِ ٱلۡمُؤۡمِنِينَ إِذۡ يُبَايِعُونَكَ تَحۡتَ ٱلشَّجَرَةِ فَعَلِمَ مَا فِي قُلُوبِهِمۡ فَأَنزَلَ ٱلسَّكِينَةَ عَلَيۡهِمۡ وَأَثَٰبَهُمۡ فَتۡحࣰ ا قَرِيبࣰ ا

God was pleased with the believers when they swore allegiance to you [Prophet] under the tree: He knew what was in their hearts and so He sent tranquillity down to them and rewarded them with a speedy triumph

Qur'ān 48:4English sense: tranquillity | Arabic sense: السكينة, سكينه

هُوَ ٱلَّذِيٓ أَنزَلَ ٱلسَّكِينَةَ فِي قُلُوبِ ٱلۡمُؤۡمِنِينَ لِيَزۡدَادُوٓاْ إِيمَٰنࣰ ا مَّعَ إِيمَٰنِهِمۡۗ وَلِلَّهِ جُنُودُ ٱلسَّمَٰوَٰتِ وَٱلۡأَرۡضِۚ وَكَانَ ٱللَّهُ عَلِيمًا حَكِيمࣰ ا

It was He who made His tranquillity descend into the hearts of the believers, to add faith to their faith––the forces of the heavens and earth belong to God; He is all knowing and all wise––

Qur'ān 2:248English sense: tranquillity | Arabic sense: سكينه

وَقَالَ لَهُمۡ نَبِيُّهُمۡ إِنَّ ءَايَةَ مُلۡكِهِۦٓ أَن يَأۡتِيَكُمُ ٱلتَّابُوتُ فِيهِ سَكِينَةࣱ مِّن رَّبِّكُمۡ وَبَقِيَّةࣱ مِّمَّا تَرَكَ ءَالُ مُوسَىٰ وَءَالُ هَٰرُونَ تَحۡمِلُهُ ٱلۡمَلَٰٓئِكَةُۚ إِنَّ فِي ذَٰلِكَ لَأٓيَةࣰ لَّكُمۡ إِن كُنتُم مُّؤۡمِنِينَ

Their prophet said to them, ‘The sign of his authority will be that the Ark [of the Covenant] will come to you. In it there will be [the gift of] tranquillity from your Lord and relics of the followers of Moses and Aaron, carried by the angels. There is a sign in this for you if you believe.’

Qur'ān 30:21English sense: tranquillity

وَمِنۡ ءَايَٰتِهِۦٓ أَنۡ خَلَقَ لَكُم مِّنۡ أَنفُسِكُمۡ أَزۡوَٰجࣰ ا لِّتَسۡكُنُوٓاْ إِلَيۡهَا وَجَعَلَ بَيۡنَكُم مَّوَدَّةࣰ وَرَحۡمَةًۚ إِنَّ فِي ذَٰلِكَ لَأٓيَٰتࣲ لِّقَوۡمࣲ يَتَفَكَّرُونَ

Another of His signs is that He created spouses from among yourselves for you to live with in tranquillity: He ordained love and kindness between you. There truly are signs in this for those who reflect

Qur'ān 48:26English sense: tranquillity

إِذۡ جَعَلَ ٱلَّذِينَ كَفَرُواْ فِي قُلُوبِهِمُ ٱلۡحَمِيَّةَ حَمِيَّةَ ٱلۡجَٰهِلِيَّةِ فَأَنزَلَ ٱللَّهُ سَكِينَتَهُۥ عَلَىٰ رَسُولِهِۦ وَعَلَى ٱلۡمُؤۡمِنِينَ وَأَلۡزَمَهُمۡ كَلِمَةَ ٱلتَّقۡوَىٰ وَكَانُوٓاْ أَحَقَّ بِهَا وَأَهۡلَهَاۚ وَكَانَ ٱللَّهُ بِكُلِّ شَيۡءٍ عَلِيمࣰ ا

While the disbelievers had fury in their hearts- the fury of ignorance- God sent His tranquillity down on to His Messenger and the believers and made binding on them [their] promise to obey God, for that was more appropriate and fitting for them. God has full knowledge of all things

Qur'ān 2:63English sense: contentment

وَإِذۡ أَخَذۡنَا مِيثَٰقَكُمۡ وَرَفَعۡنَا فَوۡقَكُمُ ٱلطُّورَ خُذُواْ مَآ ءَاتَيۡنَٰكُم بِقُوَّةࣲ وَٱذۡكُرُواْ مَا فِيهِ لَعَلَّكُمۡ تَتَّقُونَ

Remember when We took your pledge, and made the mountain tower high above you, and said, ‘Hold fast to what We have given you and bear its contents in mind, so that you may be conscious of God.’

Tafsīr

التفسير6 shown

Commentary on the verses above, at most two editions per verse.

en-al-jalalayn on 48:18en-al-jalalayncommentary on an ayah this subject surfaced

Verily God was pleased with the believers when they pledged allegiance to you at al-Hudaybiyya under the tree this was an acacia — they these believers numbered 1300 or more; he took an oath of allegiance from them that they would fight against Quraysh and not attempt to flee from death. And He God knew what was in their hearts of sincerity and loyalty so He sent down the spirit of Peace upon them and rewarded them with a near victory which was the conquest of Khaybar following their departure from al-Hudaybiyya

en-al-jalalayn on 48:4en-al-jalalayncommentary on an ayah this subject surfaced

He it is Who sent down the spirit of Peace Divine reassurance into the hearts of the believers that they might add faith to their faith by way of their embracing of the legal stipulations of religion for every time He revealed one of these they would believe in it — including the command to struggle. And to God belong the hosts of the heavens and the earth and so if He wanted to bring victory to His religion by means of others He would have done so. And God is ever Knower of His creatures Wise in His actions in other words He is ever possessed of such attributes;

en-tafisr-ibn-kathir on 48:18en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

Indeed, Allah was pleased with the believers when they gave the pledge to you under the tree, He knew what was in their hearts, and He sent down As-Sakinah upon them, and He rewarded them with a near victory (18)And abundant spoils that they will capture. And Allah is Ever All-Mighty, All-Wise (19) Good News to the Participants of the Ridwan Pledge of Allah's Pleasure and earning Spoils of War Allah declares that He is pleased with the believers who gave the pledge to the Messenger of Allah ﷺ under the tree. We mentioned the number of these believers as being one thousand and four hundred and that the tree was a Samurah tree, located in the area of Hudaybiyyah. Al-Bukhari narrated from Tariq that 'Abdur-Rahman said, "I went on Hajj and passed by people praying and asked, 'What is this Masjid?' They said, 'This is the tree where the Messenger of Allah ﷺ took the pledge of Ar-Ridwan.' S

en-tafisr-ibn-kathir on 48:4en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

He it is Who sent down As-Sakinah into the hearts of the believers, that they may grow more in faith along with their faith. And to Allah belong the armies of the heavens and the earth, and Allah is Ever All-Knower, All-Wise (4)That He may admit the believing men and the believing women to Gardens under which rivers flow to abide therein forever, and He may expiate from them their sins; and that is with Allah supreme success (5)And that He may punish the hypocrites men and women, and also the idolators men and women, who think evil thoughts about Allah, for them is a disgraceful torment. And the anger of Allah is upon them, and He has cursed them and prepared Hell for them and worst indeed is that destination (6)And to Allah belong the armies of the heavens and the earth. And Allah is Ever All-Powerful, All-Wise (7) Allah sent down the Sakinah into the Hearts of the Believers Allah the

en-al-jalalayn on 2:248en-al-jalalayncommentary on an ayah this subject surfaced

And their prophet said to them after they had demanded a sign of his kingship ‘The sign of his kingship is that there will come to you the Ark a chest containing the images of the prophets which God sent down to Adam and which was handed down to them sc. the Israelites until the Amalekites seized it from them in battle. They used to commence fighting invoking it before their enemy and marching behind it as well as experience peacefulness in its presence as God says therein is a Spirit of Peace reassurance for your hearts from your Lord and a remnant of what the folk of Moses and the folk of Aaron left behind which were Moses’s pair of sandals and his staff Aaron’s turban a measure qafīz of the manna that used to come down on them and the pieces of the broken tablets the angels bearing it tahmiluhu l-malā’ikatu the circumstantial qualifier referring to the subject of the verb ya’tiyakum ‘

en-tafisr-ibn-kathir on 2:248en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

And their Prophet said to them: "Verily! The sign of His kingdom is that there shall come to you At-Tabut, wherein is Sakinah (peace and reassurance) from your Lord and a remnant of that which Musa (Moses) and Harun (Aaron) left behind, carried by the angels. Verily, in this is a sign for you if you are indeed believers (248) Their Prophet then proclaimed, "The sign of the blessings of Talut's kingship over you is that Allah will give you back the Tabut (wooden box) that has been taken from you." Allah said: فِيهِ سَكِينَةٌ مِّن رَّبِّكُمْ (wherein is Sakinah from your Lord) meaning, peace (or grace) and reassurance. 'Abdur-Razzaq stated that Qatadah said: فِيهِ سَكِينَةٌ (wherein is Sakinah) means grace. In addition, Ar-Rabi' said that Sakinah means mercy. This is also the meaning given by Ibn 'Abbas, as Al-'Awfi narrated. Allah then said: وَبَقِيَّةٌ مِّمَّا تَرَكَ آلُ مُوسَىٰ و

Ḥadīth

الحديث6 shown

Sound narrations only, and never matched by text. A narration appears here because a compiler filed it under a chapter this subject maps to, or because someone read it and anchored it. Each row says which.

Jami' at-Tirmidhi 2607The Book On Faithfiled here by the compiler

حَدَّثَنَا قُتَيْبَةُ، حَدَّثَنَا اللَّيْثُ، عَنْ عُقَيْلٍ، عَنِ الزُّهْرِيِّ، أَخْبَرَنِي عُبَيْدُ اللَّهِ بْنُ عَبْدِ اللَّهِ بْنِ عُتْبَةَ بْنِ مَسْعُودٍ، عَنْ أَبِي هُرَيْرَةَ، قَالَ لَمَّا تُوُفِّيَ رَسُولُ اللَّهِ صلى الله عليه وسلم وَاسْتُخْلِفَ أَبُو بَكْرٍ بَعْدَهُ كَفَرَ مَنْ كَفَرَ مِنَ الْعَرَبِ فَقَالَ عُمَرُ بْنُ الْخَطَّابِ لأَبِي بَكْرٍ كَيْفَ تُقَاتِلُ النَّاسَ وَقَدْ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏ "‏ أُمِرْتُ أَنْ أُقَاتِلَ النَّاسَ حَتَّى يَقُولُوا لاَ إِلَهَ إِلاَّ اللَّهُ وَمَنْ قَالَ لاَ إِلَهَ إِلاَّ اللَّهُ عَصَمَ مِنِّي مَالَهُ وَنَفْسَهُ إِلاَّ بِحَقِّهِ وَحِسَابُهُ عَلَى اللَّهِ ‏"‏ ‏.‏ قَالَ أَبُو بَكْرٍ وَاللَّهِ لأُقَاتِلَنَّ مَنْ فَرَّقَ بَيْنَ الزَّكَاةِ وَالصَّلاَةِ فَإِنَّ الزَّكَاةَ حَقُّ الْمَالِ وَاللَّهِ لَوْ مَنَعُونِي عِقَالاً كَانُوا يُؤَدُّونَهُ إِلَى رَسُولِ اللَّهِ صلى الله عليه وسلم لَقَاتَلْتُهُمْ عَلَى مَنْعِهِ فَقَالَ عُمَرُ بْنُ الْخَطَّابِ فَوَاللَّهِ مَا هُوَ إِلاَّ أَنْ رَأَيْتُ أَنَّ اللَّهَ قَدْ شَرَحَ صَدْرَ أَبِي بَكْرٍ لِلْقِتَالِ فَعَرَفْتُ أَنَّهُ الْحَقُّ ‏.‏ قَالَ أَبُو عِيسَى هَذَا حَدِيثٌ حَسَنٌ صَحِيحٌ وَهَكَذَا رَوَى شُعَيْبُ بْنُ أَبِي حَمْزَةَ عَنِ الزُّهْرِيِّ عَنْ عُبَيْدِ اللَّهِ بْنِ عَبْدِ اللَّهِ عَنْ أَبِي هُرَيْرَةَ ‏.‏ وَرَوَى عِمْرَانُ الْقَطَّانُ هَذَا الْحَدِيثَ عَنْ مَعْمَرٍ عَنِ الزُّهْرِيِّ عَنْ أَنَسِ بْنِ مَالِكٍ عَنْ أَبِي بَكْرٍ وَهُوَ حَدِيثٌ خَطَأٌ وَقَدْ خُولِفَ عِمْرَانُ فِي رِوَايَتِهِ عَنْ مَعْمَرٍ ‏.‏

Narrated Abu Hurairah:said: "When the Messenger of Allah (ﷺ) died and Abu Bakr became the Khalifah after him, whoever disbelieved from the Arabs disbelieved, so Umar bin Al-Khattab said to Abu Bakr: 'How will you fight the people while the Messenger of Allah has said: 'I have been ordered to fight the people until they say La Ilaha Illallah, and if they say that, then their blood and wealth will be protected from me, except what it makes obligatory upon them, and their reckoning is with Allah?' So Abu Bakr said: 'By Allah I will fight whoever differentiates between Salat and Zakat. For indeed, Zakat is the right due upon wealth. And by Allah! If they withhold even (camel) tethers which they used to give to the Messenger of Allah (ﷺ) I will fight them for withholding it.' So Umar bin Al-Khattab said: 'By Allah! I saw that Allah had opened Abu Bakr's chest to fighting, so I knew that it was correct

Jami' at-Tirmidhi 2608The Book On Faithfiled here by the compiler

حَدَّثَنَا سَعِيدُ بْنُ يَعْقُوبَ الطَّالْقَانِيُّ، حَدَّثَنَا ابْنُ الْمُبَارَكِ، أَخْبَرَنَا حُمَيْدٌ الطَّوِيلُ، عَنْ أَنَسِ بْنِ مَالِكٍ، قَالَ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏ "‏ أُمِرْتُ أَنْ أُقَاتِلَ النَّاسَ حَتَّى يَشْهَدُوا أَنْ لاَ إِلَهَ إِلاَّ اللَّهُ وَأَنَّ مُحَمَّدًا عَبْدُهُ وَرَسُولُهُ وَأَنْ يَسْتَقْبِلُوا قِبْلَتَنَا وَيَأْكُلُوا ذَبِيحَتَنَا وَأَنْ يُصَلُّوا صَلاَتَنَا فَإِذَا فَعَلُوا ذَلِكَ حُرِّمَتْ عَلَيْنَا دِمَاؤُهُمْ وَأَمْوَالُهُمْ إِلاَّ بِحَقِّهَا لَهُمْ مَا لِلْمُسْلِمِينَ وَعَلَيْهِمْ مَا عَلَى الْمُسْلِمِينَ ‏"‏ ‏.‏ وَفِي الْبَابِ عَنْ مُعَاذِ بْنِ جَبَلٍ وَأَبِي هُرَيْرَةَ ‏.‏ قَالَ أَبُو عِيسَى هَذَا حَدِيثٌ حَسَنٌ صَحِيحٌ غَرِيبٌ مِنْ هَذَا الْوَجْهِ ‏.‏ وَقَدْ رَوَاهُ يَحْيَى بْنُ أَيُّوبَ عَنْ حُمَيْدٍ عَنْ أَنَسٍ نَحْوَ هَذَا ‏.‏

Narrated Anas bin Malik:that the Messenger of Allah (ﷺ) said: "I have been ordered to fight the people until they bear witness to La Ilaha Illallah, and that Muhammad is His servant and Messenger, and they face our Qiblah, eat our slaughtered (meat), and perform our Salat. And if they do that, then their blood and wealth will be unlawful to us, except with its due right. For them shall be whatever is for the Muslims, and they shall be obliged with that which the Muslims are obliged

Sahih al-Bukhari 10Belieffiled here by the compiler

حَدَّثَنَا آدَمُ بْنُ أَبِي إِيَاسٍ، قَالَ حَدَّثَنَا شُعْبَةُ، عَنْ عَبْدِ اللَّهِ بْنِ أَبِي السَّفَرِ، وَإِسْمَاعِيلَ، عَنِ الشَّعْبِيِّ، عَنْ عَبْدِ اللَّهِ بْنِ عَمْرٍو ـ رضى الله عنهما ـ عَنِ النَّبِيِّ صلى الله عليه وسلم قَالَ ‏ "‏ الْمُسْلِمُ مَنْ سَلِمَ الْمُسْلِمُونَ مِنْ لِسَانِهِ وَيَدِهِ، وَالْمُهَاجِرُ مَنْ هَجَرَ مَا نَهَى اللَّهُ عَنْهُ ‏"‏‏.‏ قَالَ أَبُو عَبْدِ اللَّهِ وَقَالَ أَبُو مُعَاوِيَةَ حَدَّثَنَا دَاوُدُ عَنْ عَامِرٍ قَالَ سَمِعْتُ عَبْدَ اللَّهِ عَنِ النَّبِيِّ صلى الله عليه وسلم‏.‏ وَقَالَ عَبْدُ الأَعْلَى عَنْ دَاوُدَ عَنْ عَامِرٍ عَنْ عَبْدِ اللَّهِ عَنِ النَّبِيِّ صلى الله عليه وسلم‏.‏

Narrated 'Abdullah bin 'Amr: The Prophet (ﷺ) said, "A Muslim is the one who avoids harming Muslims with his tongue and hands. And a Muhajir (emigrant) is the one who gives up (abandons) all what Allah has forbidden

Sahih al-Bukhari 8Belieffiled here by the compiler

حَدَّثَنَا عُبَيْدُ اللَّهِ بْنُ مُوسَى، قَالَ أَخْبَرَنَا حَنْظَلَةُ بْنُ أَبِي سُفْيَانَ، عَنْ عِكْرِمَةَ بْنِ خَالِدٍ، عَنِ ابْنِ عُمَرَ ـ رضى الله عنهما ـ قَالَ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏ "‏ بُنِيَ الإِسْلاَمُ عَلَى خَمْسٍ شَهَادَةِ أَنْ لاَ إِلَهَ إِلاَّ اللَّهُ وَأَنَّ مُحَمَّدًا رَسُولُ اللَّهِ، وَإِقَامِ الصَّلاَةِ، وَإِيتَاءِ الزَّكَاةِ، وَالْحَجِّ، وَصَوْمِ رَمَضَانَ ‏"‏‏.‏

Narrated Ibn 'Umar: Allah's Messenger (ﷺ) said: Islam is based on (the following) five (principles): 1. To testify that none has the right to be worshipped but Allah and Muhammad is Allah's Messenger (ﷺ). 2. To offer the (compulsory congregational) prayers dutifully and perfectly. 3. To pay Zakat (i.e. obligatory charity) . 4. To perform Hajj. (i.e. Pilgrimage to Mecca) 5. To observe fast during the month of Ramadan

Sunan an-Nasa'i 4985Faith And Its Signsfiled here by the compiler

حَدَّثَنَا أَبُو عَبْدِ الرَّحْمَنِ، أَحْمَدُ بْنُ شُعَيْبٍ - مِنْ لَفْظِهِ - قَالَ أَنْبَأَنَا عَمْرُو بْنُ عَلِيٍّ، قَالَ حَدَّثَنَا عَبْدُ الرَّحْمَنِ، قَالَ حَدَّثَنَا إِبْرَاهِيمُ بْنُ سَعْدٍ، عَنِ الزُّهْرِيِّ، عَنْ سَعِيدِ بْنِ الْمُسَيَّبِ، عَنْ أَبِي هُرَيْرَةَ، أَنَّ رَسُولَ اللَّهِ صلى الله عليه وسلم سُئِلَ أَىُّ الأَعْمَالِ أَفْضَلُ قَالَ ‏ "‏ الإِيمَانُ بِاللَّهِ وَرَسُولِهِ ‏"‏ ‏.‏

It was narrated from Abu Hurairah that:The Messenger of Allah [SAW] was asked: "Which deed is best?" "He said: Faith in Allah [SWT] and His messenger [SAW]

Sunan an-Nasa'i 4986Faith And Its Signsfiled here by the compiler

أَخْبَرَنَا هَارُونُ بْنُ عَبْدِ اللَّهِ، قَالَ حَدَّثَنَا حَجَّاجٌ، عَنِ ابْنِ جُرَيْجٍ، قَالَ حَدَّثَنَا عُثْمَانُ بْنُ أَبِي سُلَيْمَانَ، عَنْ عَلِيٍّ الأَزْدِيِّ، عَنْ عُبَيْدِ بْنِ عُمَيْرٍ، عَنْ عَبْدِ اللَّهِ بْنِ حُبْشِيٍّ الْخَثْعَمِيِّ، أَنَّ النَّبِيَّ صلى الله عليه وسلم سُئِلَ أَىُّ الأَعْمَالِ أَفْضَلُ فَقَالَ ‏ "‏ إِيمَانٌ لاَ شَكَّ فِيهِ وَجِهَادٌ لاَ غُلُولَ فِيهِ وَحَجَّةٌ مَبْرُورَةٌ ‏"‏ ‏.‏

It was narrated from Abdullah bin Hubshi Al-Khath'ami that:The Prophet [SAW] was asked: "Which deed is best?" He said: "Faith in which there is no doubt, Jihad in which there is no Ghulul, and Hajjatun Mabrur

Classical works

كتب التراث6 shown

Arabic originals, reached through the subject’s Arabic senses. Interpretive sources, never proof of a ruling.

madarij §1981madarijArabic sense: السكينة, الطمانينة, سكينه, طمانينه

قال صاحب المنازل : هو من أول مقامات الطمأنينة يعني بمقامات الطمأنينة كالسكينة واليقين والثقة بالله ونحوها فالإخبات : مقدمتها ومبدؤها قال : وهو ورود المأمن من الرجوع والتردد

madarij §3544madarijArabic sense: السكينة, الطمانينة, سكينه, طمانينه

هذا وفي الصفح والعفو والحلم : من الحلاوة والطمأنينة والسكينة وشرف النفس وعزها ورفعتها عن تشفيها بالانتقام : ما ليس شيء منه في المقابلة والانتقام

madarij §4357madarijArabic sense: السكينة, الطمانينة, سكينه, طمانينه

بالعيان وبينها وبين السكينة فرقان : أحدهما : أن السكينة صوله تورث خمود الهيبة أحيانا و الطمأنينة سكون أمن في استراحة أنس والثاني : أن السكينة تكون نعتا وتكون حينا بعد حين و الطمأنينة لا تفارق صاحبها الطمأنينة موجب السكينة وأثر من آثارها وكأنها نهاية السكينة

madarij §1987madarijArabic sense: السكينة, الطمانينة, سكينه, طمانينه

يقول : تغلب عصمته شهوته وتقهرها وتستوفي جميع أجزائها فإذا استوفت العصمة جميع أجزاء الشهوة : فذلك دليل على إخباته ودخوله في مقام الطمأنينة ونزوله أول منازلها وخلاصه في هذا المنزل من تردد الخواطر بين الإقبال والإدبار والرجوع والعزم إلى الاستقامة والعزم الجازم والجد في السير وذلك علامة السكينة

madarij §4366madarijArabic sense: السكينة, الطمانينة, سكينه, طمانينه

قد تقدم أن الطمأنينة بذكر الله بكلامه وكتابه ولا ريب أن الذي ذكره في هذه الدرجة : هو من جملة الطمأنينة بذكره وهي أهم من ذلك فذكر طمأنينة الخائف إلى الرجاء فإن الخائف إذا طال عليه الخوف واشتد به وأراد الله عز وجل أن يريحه ويحمل عنه : أنزل عليه السكينة فاستراح قلبه إلى الرجاء واطمأن به وسكن لهيب خوفه وأما طمأنينة الضجر إلى الحكم

madarij §3166madarijArabic sense: السكينة, الطمانينة, سكينه, طمانينه, فلاح

ونكتة المسألة : إيمانه بأن قضاء الرب تعالى خير له كما قال النبي والذي نفسي بيده لا يقضي الله للمؤمن قضاء إلا كان خيرا له إن أصابته سراء شكر فكان خيرا له وإن أصابته ضراء صبر فكان خيرا له وليس ذلك إلا للمؤمن الحادي عشر : أن يعلم أن تمام عبوديته في جريان ما يكرهه من الأحكام عليه ولو لم يجر عليه منها إلا ما يحب لكان أبعد شيء عن عبودية ربه فلا تتم له عبوديته من الصبر والتوكل والرضى والتضرع والافتقار والذل والخضوع وغيرها إلا بجريان القدر له بما يكرهه وليس الشأن في الرضى بالقضاء الملائم للطبيعة إنما الشأن في القضاء المؤلم المنافر للطبع الثاني عشر : أن يعلم أن رضاه عن ربه سبحانه وتعالى في جميع الحالات يثمر رضى ربه عنه فإذا رضي عنه بالقليل من الرزق : رضي ربه عنه بالقليل من العمل وإذا رضي عنه في جميع الحالات واستوت عنده وجده أسرع شيء إلى رضاه إذا ترضاه وتملقه الثالث عشر : أن يعلم أن أعظم راحته وسروره ونعيمه : فى الرضى عن ربه تعالى وتقدس في جميع الحالات فإن الرضى باب الله الأعظم ومستراح العارفين وج

Research library

المكتبة البحثية6,178 works held

Peer-reviewed work held with its DOI and abstract, labelled with the study design its publication types report. None of it has been read or assessed, so nothing here may be cited as showing anything. Retracted work is held for the record but never listed; a review that a later version replaced is listed under its replacement and marked.

10.1080/13607863.2013.856858Aging & mental health (2014)MEDLINE-indexed journal, not yet read by us; matched on Happiness, Personal Satisfaction, Quality of Life, quality of life, well-being

A program of positive intervention in the elderly: memories, gratitude and forgiveness.: Objective: The main goal of this study has been to increase the quality of life in people of over 60 years through a positive psychology intervention. Method: We employed a program which consists of training based on autobiographical memory, forgiveness and gratitude. The sample consisted of 46 participants aged 60-93 years. State and trait anxiety, depression, general memory, specific memories, life satisfaction and subjective happiness were measured. Results: The results revealed that particip

10.3390/nu12010115Nutrients (2020)MEDLINE-indexed journal, not yet read by us; matched on Quality of Life, Mental Health, Quality of Life, flourishing, Mental Health, quality of life, well-being

Fruit and Vegetable Intake and Mental Health in Adults: A Systematic Review.: The role of a properly balanced diet in the prevention and treatment of mental disorders has been suggested, while vegetables and fruits have a high content of nutrients that may be of importance in the case of depressive disorders. The aim of the study was to conduct a systematic review of the observational studies analyzing association between fruit and vegetable intake and mental health in adults. The search adhered to the guidelines of Preferred Reporting Items for Systematic Reviews and Met

10.1093/geront/gny168The Gerontologist (2019)MEDLINE-indexed journal, not yet read by us; matched on Personal Satisfaction, Quality of Life, Quality of Life, quality of life, well-being

Influence of Positive Aspects of Dementia Caregiving on Caregivers' Well-Being: A Systematic Review.: Background and objectives: There is a growing evidence base that informal caregivers can identify positive aspects of providing care and that this may have a beneficial influence on their well-being. The aim of this systematic review was to explore how positive aspects of caregiving (PAC) affects the well-being of caregivers of people with dementia. Research design and methods: We searched electronic databases for quantitative studies exploring the association between PAC and caregiver well-bein

10.1186/s12884-018-2087-4BMC pregnancy and childbirth (2018)MEDLINE-indexed journal, not yet read by us; matched on Happiness, Quality of Life, Quality of Life, quality of life, well-being

Factors influencing the quality of life of pregnant women: a systematic review.: Background: Pregnancy is a period of transition with important physical and emotional changes. Even in uncomplicated pregnancies, these changes can affect the quality of life (QOL) of pregnant women, affecting both maternal and infant health. The objectives of this study were to describe the quality of life during uncomplicated pregnancy and to assess its associated socio-demographic, physical and psychological factors in developed countries. Methods: A systematic review was performed according

10.1186/s12906-021-03482-0BMC complementary medicine and therapies (2022)MEDLINE-indexed journal, not yet read by us; matched on Personal Satisfaction, Quality of Life, Quality of Life, quality of life, well-being

Does tai chi improve psychological well-being and quality of life in patients with cardiovascular disease and/or cardiovascular risk factors? A systematic review.: Background: Psychological risk factors have been recognised as potential, modifiable risk factors in the development and progression of cardiovascular disease (CVD). Tai Chi, a mind-body exercise, has the potential to improve psychological well-being and quality of life. We aim to assess the effects and safety of Tai Chi on psychological well-being and quality of life in people with CVD and/or cardiovascular risk factors. Methods: We searched for randomised controlled trials evaluating Tai Chi f

10.1007/s00520-020-05383-3Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2020)MEDLINE-indexed journal, not yet read by us; matched on Quality of Life, Mental Health, Quality of Life, Mental Health, quality of life

Effects of Internet-based psycho-educational interventions on mental health and quality of life among cancer patients: a systematic review and meta-analysis.: Purpose: To systematically review evidence regarding the benefits of Internet-based psycho-educational interventions among cancer patients. Methods: We performed a systematic review with meta-analysis and qualitative evidence synthesis. Systematic searches for published studies in English or Chinese identified eligible randomized and clinical controlled trials. The following databases were searched: Medline, Embase, CINAHL, PsycINFO, Web of Science, Cochrane Central Register of Controlled Trials

Research library, full list

1951 to 1975 of 6,178
Schulze T, Maercker A, Horn AB (2014)reviewMEDLINE-indexed journal, not yet read by usGerontology14 citations

Mental health and multimorbidity: psychosocial adjustment as an important process for quality of life.

Background: Multimorbidity (the co-occurrence of two or more chronic diseases) can be seen as a prototypical situation in which psychosocial adjustment is required. Even though most patients adapt successfully, a significant number of individuals show adaptation problems and develop additional mental health problems. Objective: For this reason, this article focuses on the importance of psychosocial adaptation as a core process in the context of quality of life. Results: Important findings pointing at the association between multimorbidity and mental health are summarized, and the stress-response perspective on psychosocial adjustment is introduced. Furthermore, cognitive-affective processing of the disease (in the context of illness perceptions) and interpersonal emotion regulation are presented as relevant examples for processes involved in psychological adaptation to multimorbidity. As

matched on Quality of Life (mesh), Mental Health (mesh), quality of life (text)

Charles ST (2010)reviewMEDLINE-indexed journal, not yet read by usPsychological bulletin638 citations

Strength and vulnerability integration: a model of emotional well-being across adulthood.

The following article presents the theoretical model of strength and vulnerability integration (SAVI) to explain factors that influence emotion regulation and emotional well-being across adulthood. The model posits that trajectories of adult development are marked by age-related enhancement in the use of strategies that serve to avoid or limit exposure to negative stimuli but by age-related vulnerabilities in situations that elicit high levels of sustained emotional arousal. When older adults avoid or reduce exposure to emotional distress, they often respond better than younger adults; when they experience high levels of sustained emotional arousal, however, age-related advantages in emotional well-being are attenuated, and older adults are hypothesized to have greater difficulties returning to homeostasis. SAVI provides a testable model to understand the literature on emotion and aging

matched on Personal Satisfaction (mesh), Mental Health (mesh), well-being (text)

Andrykowski MA, Lykins E, Floyd A (2008)reviewMEDLINE-indexed journal, not yet read by usSeminars in oncology nursing115 citations

Psychological health in cancer survivors.

Objectives: The prevalence of both negative (distress) and positive responses (growth, well-being) to the cancer experience is examined and difficulties in establishing the prevalence of these responses discussed. A conceptual framework for understanding factors associated with psychological health in cancer survivors is presented. Finally, strategies for promoting psychological health in cancer survivors are examined. Data sources: Review of the literature. Conclusion: Psychological health in cancer survivors is defined by the presence or absence of distress as well as the presence or absence of positive well-being and psychological growth. Furthermore, psychological health in cancer survivors is determined by the balance between two classes of factors: the stress and burden posed by the cancer experience and the resources available for coping with this stress and burden. Implications f

matched on Quality of Life (mesh), Mental Health (mesh), well-being (text)

Koenig HG (2008)reviewMEDLINE-indexed journal, not yet read by usThe Journal of nervous and mental disease208 citations

Concerns about measuring "spirituality" in research.

Spirituality is increasingly being examined as a construct related to mental and physical health. The definition of spirituality, however, has been changing. Traditionally, spirituality was used to describe the deeply religious person, but it has now expanded to include the superficially religious person, the religious seeker, the seeker of well-being and happiness, and the completely secular person. Instruments used to measure spirituality reflect this trend. These measures are heavily contaminated with questions assessing positive character traits or mental health: optimism, forgiveness, gratitude, meaning and purpose in life, peacefulness, harmony, and general well-being. Spirituality, measured by indicators of good mental health, is found to be correlated with good mental health. This research has been reported in some of the world's top medical journals. Such associations are meanin

matched on Quality of Life (mesh), Mental Health (mesh), well-being (text)

Restout J, Bernache-Assollant I, Morizio C, Boujut A, Angelini L, Tchalla A, Perrochon A (2023)reviewMEDLINE-indexed journal, not yet read by usJournal of the American Medical Directors Association22 citations

Fully Immersive Virtual Reality Using 360° Videos to Manage Well-Being in Older Adults: A Scoping Review.

Objective: The development of negative behavioral and psychosocial factors (depression, anxiety, apathy, etc) is associated with poor well-being, which can contribute to health issues in ageing, especially in the context of COVID-19. Despite its relative novelty, fully immersive virtual reality (VR) interventions through 360° immersive videos are becoming more accessible and flexible and constitute an emerging method to potentially enhance well-being. The aim of this scoping review is to assess the effectiveness of 360° interventions on well-being in older adults with or without cognitive impairment, as well as cybersickness and attitudes toward this technology. Design: Scoping review. Setting and participants: Older adults with or without cognitive impairment. Methods: The PRISMA-SR guideline was followed. Four databases were used, and we selected articles published until April 2022. We

matched on Quality of Life (mesh), Mental Health (keyword), quality of life (text), well-being (text)

Bright K, Dube L, Hayden KA, Gordon JL (2020)MEDLINE-indexed journal, not yet read by usBMJ open9 citations

Effectiveness of psychological interventions on mental health, quality of life and relationship satisfaction for individuals and/or couples undergoing fertility treatment: a systematic review and meta-analysis protocol.

Introduction: Infertility is a global public health problem affecting men, women and couples worldwide. The medical implications of infertility are often of primary focus in healthcare settings, but the experience of infertility also has a considerable social, emotional and psychological impact. Interventions aimed at alleviating psychological symptoms in individual and/or couples undergoing fertility treatment requires a systematic and comprehensive review of the literature to determine the efficacy of psychological interventions. The objective of this review is to evaluate the effectiveness, feasibility and acceptability of psychological interventions for individuals and/or couples seeking fertility to treat anxiety, depression, distress, quality of life and relationship satisfaction, as well as improve pregnancy rates. Methods and analysis: The search strategy will involve 11 database

matched on Personal Satisfaction (mesh), Quality of Life (mesh), Mental Health (mesh), Mental Health (keyword), quality of life (text)

Steptoe A (2019)MEDLINE-indexed journal, not yet read by usAnnual review of public health211 citations

Happiness and Health.

Research into the relationship between happiness and health is developing rapidly, exploring the possibility that impaired happiness is not only a consequence of ill-health but also a potential contributor to disease risk. Happiness encompasses several constructs, including affective well-being (feelings of joy and pleasure), eudaimonic well-being (sense of meaning and purpose in life), and evaluative well-being (life satisfaction). Happiness is generally associated with reduced mortality in prospective observational studies, albeit with several discrepant results. Confounding and reverse causation are major concerns. Associations with morbidity and disease prognosis have also been identified for a limited range of health conditions. The mechanisms potentially linking happiness with health include lifestyle factors, such as physical activity and dietary choice, and biological processes,

matched on Happiness (mesh), Personal Satisfaction (mesh), Quality of Life (mesh), well-being (text)

Lombardo P, Jones W, Wang L, Shen X, Goldner EM (2018)MEDLINE-indexed journal, not yet read by usBMC public health133 citations

The fundamental association between mental health and life satisfaction: results from successive waves of a Canadian national survey.

Background: A self-reported life satisfaction question is routinely used as an indicator of societal well-being. Several studies support that mental illness is an important determinant for life satisfaction and improvement of mental healthcare access therefore could have beneficial effects on a population's life satisfaction. However, only a few studies report the relationship between subjective mental health and life satisfaction. Subjective mental health is a broader concept than the presence or absence of psychopathology. In this study, we examine the strength of the association between a self-reported mental health question and self-reported life satisfaction, taking into account other relevant factors. Methods: We conducted this analysis using successive waves of the Canadian Community Health Survey (CCHS) collected between 2003 and 2012. Respondents included more than 400,000 parti

matched on Personal Satisfaction (mesh), Mental Health (mesh), Happiness (keyword), Quality of Life (keyword), Mental Health (keyword), well-being (text)

Diener E, Ng W, Harter J, Arora R (2010)MEDLINE-indexed journal, not yet read by usJournal of personality and social psychology140 citations

Wealth and happiness across the world: material prosperity predicts life evaluation, whereas psychosocial prosperity predicts positive feeling.

The Gallup World Poll, the first representative sample of planet Earth, was used to explore the reasons why happiness is associated with higher income, including the meeting of basic needs, fulfillment of psychological needs, increasing satisfaction with one's standard of living, and public goods. Across the globe, the association of log income with subjective well-being was linear but convex with raw income, indicating the declining marginal effects of income on subjective well-being. Income was a moderately strong predictor of life evaluation but a much weaker predictor of positive and negative feelings. Possessing luxury conveniences and satisfaction with standard of living were also strong predictors of life evaluation. Although the meeting of basic and psychological needs mediated the effects of income on life evaluation to some degree, the strongest mediation was provided by standa

matched on Happiness (mesh), Personal Satisfaction (mesh), Quality of Life (mesh), well-being (text)

Ruch W, Proyer RT, Weber M (2010)MEDLINE-indexed journal, not yet read by usZeitschrift fur Gerontologie und Geriatrie15 citations

Humor as a character strength among the elderly: empirical findings on age-related changes and its contribution to satisfaction with life.

Background: Positive psychology studies what is best in people. In their classification of strengths and virtues, Peterson and Seligman [11] assign humor to the virtue of transcendence. Thus far, there is no specific study that deals with age-related changes in humor (as a strength of character) across a lifespan and its relation to well-being in the elderly. Participants and methods: A total of n=42,964 participants completed an online questionnaire on humor as a strength of character. Participants also completed the Satisfaction with Life Scale and the Orientations to Happiness Scale. Results: In a cross-sectional design, the scores for humor decreased until the age of 50. Men between 51 and 62 years had higher scores; there was a trend for women older than 70 to score higher (but this was not statistically significant). Humor was robustly positively correlated with life satisfaction,

matched on Happiness (mesh), Personal Satisfaction (mesh), Quality of Life (mesh), well-being (text)

Kattainen E, Meriläinen P, Sintonen H (2006)MEDLINE-indexed journal, not yet read by usEuropean journal of cardiovascular nursing40 citations

Sense of coherence and health-related quality of life among patients undergoing coronary artery bypass grafting or angioplasty.

Background: Every year, 4 million people die from cardiovascular disease (CAD) in Europe. As many as 800,000 of them die before they reach the age of 65. The ischemic heart disease is also the most common cause of death in Finland. The invasive treatments of the CAD, coronary artery bypass grafting (CABG) and percutaneous transluminal coronary angioplasty (PTCA) relieve symptoms and increase patient's health-related quality of life (HRQoL) in most of the cases. In this paper sense of coherence is discussed as related to health-related quality of life among CABG and PTCA patients in a one-year follow-up. Sample: The study sample consisted of consecutive male (N=439) and female (N=176) patients who were treated with the elective CABG or PTCA. The baseline data before the interventions were collected by structured interviews, the follow-up data by mailed self-administered questionnaires six

matched on Happiness (mesh), Personal Satisfaction (mesh), Quality of Life (mesh), quality of life (text)

Guzek D, Kołota A, Lachowicz K, Skolmowska D, Stachoń M, Głąbska D (2021)reviewMEDLINE-indexed journal, not yet read by usJournal of clinical medicine26 citations

Association between Vitamin D Supplementation and Mental Health in Healthy Adults: A Systematic Review.

Vitamin D is considered to be a crucial factor that influences symptoms of depression, negative emotions, and quality of life, but to date, no systematic review has been conducted with regard to its effect on other domains of mental health. The aim of the study was to evaluate the influence of vitamin D supplementation on mental health in healthy adults. The systematic review was registered in the PROSPERO database (CRD42020155779) and performed according to the PRISMA guidelines. The literature search was conducted in PubMed and Web of Science databases and included intervention studies published until October 2019. The human studies were included if the supplementation regimen involved the administration of a specified dosage of vitamin D to an adult sample. A total of 7613 records were screened and assessed independently by two researchers, based on their title, abstract, and full tex

matched on Quality of Life (keyword), flourishing (text), Mental Health (keyword), quality of life (text), well-being (text)

Ghimire S, Baral BK, Karmacharya I, Callahan K, Mishra SR (2018)MEDLINE-indexed journal, not yet read by usHealth and quality of life outcomes45 citations

Life satisfaction among elderly patients in Nepal: associations with nutritional and mental well-being.

Background: Nepal's demography is aging rapidly, yet few studies to date have examined how this has affected the health and well-being of the elderly, defined as those above 60 years in Nepal's Senior Citizen Act (2006). Our study, abbreviated NepEldQOLII, aims to assess perceived life satisfaction, and evaluate its relationship with nutritional health and mental well-being among the burgeoning Nepalese elderly population. Methods: A cross-sectional survey among 289 Nepalese elderly, aged ≥60 years, attending an outpatient clinic of a hospital in Kathmandu, Nepal was conducted. Nutritional status, depression, and life satisfaction were assessed by a mini-nutritional assessment scale (range: 0-14), a geriatric depression scale (range: 0-15), and a satisfaction with life scale (range: 5-35), respectively. Mediation analyses, adjusted for age, sex, marital status, and family type, were used

matched on Personal Satisfaction (mesh), Quality of Life (mesh), Mental Health (mesh), quality of life (text), well-being (text)

Salsman JM, Lai JS, Hendrie HC, Butt Z, Zill N, Pilkonis PA, Peterson C, Stoney CM, Brouwers P, Cella D (2014)MEDLINE-indexed journal, not yet read by usQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation101 citations

Assessing psychological well-being: self-report instruments for the NIH Toolbox.

Objective: Psychological well-being (PWB) has a significant relationship with physical and mental health. As a part of the NIH Toolbox for the Assessment of Neurological and Behavioral Function, we developed self-report item banks and short forms to assess PWB. Study design and setting: Expert feedback and literature review informed the selection of PWB concepts and the development of item pools for positive affect, life satisfaction, and meaning and purpose. Items were tested with a community-dwelling US Internet panel sample of adults aged 18 and above (N = 552). Classical and item response theory (IRT) approaches were used to evaluate unidimensionality, fit of items to the overall measure, and calibrations of those items, including differential item function (DIF). Results: IRT-calibrated item banks were produced for positive affect (34 items), life satisfaction (16 items), and meanin

matched on Personal Satisfaction (mesh), Quality of Life (mesh), Mental Health (mesh), quality of life (text), well-being (text)

Eime RM, Harvey JT, Brown WJ, Payne WR (2010)MEDLINE-indexed journal, not yet read by usMedicine and science in sports and exercise70 citations

Does sports club participation contribute to health-related quality of life?

Unlabelled: Given the social nature of participation in sport, we hypothesized that club sports participants would have greater well-being and quality of life than participants in other forms of physical activity (PA). Purpose: The purpose of this study was to examine health-related quality of life and life satisfaction in women who participate in three contrasting forms of PA: club sport, gym activities, and walking. Methods: This was a cross-sectional study of the relationship between type of PA setting and measures of health-related quality of life (Short-Form Health Survey [SF-36]) and life satisfaction in 818 women living in rural Victoria, Australia, in 2007. Data were also compared with those from a normative sample of 2345 women. Results: After adjustment for potential confounders (age, education, marital status, children aged <16 yr, perceived financial stress, and level of recr

matched on Personal Satisfaction (mesh), Quality of Life (mesh), Mental Health (mesh), quality of life (text), well-being (text)

Health outcomes in spinal muscular atrophy type 1 following AVXS-101 gene replacement therapy.

Background: Spinal Muscular Atrophy type 1 (SMA1) is a rare genetic neuromuscular disease where 75% of SMA1 patients die/require permanent-ventilation by 13.6 months. This study assessed the health outcomes of SMA1 infants treated with AVXS-101 gene replacement therapy. Methods: Twelve genetically confirmed SMA1 infants with homozygous deletions of the SMN1 gene and two SMN2 gene copies received a one-time intravenous proposed therapeutic dose of AVXS-101 in an open label study conducted between December 2014 and 2017. Patients were followed for 2-years post-treatment for outcomes including (1) pulmonary interventions; (2) nutritional interventions; (3) swallow function; (4) hospitalization rates; and (5) motor function. Results: All 12 patients completed the study. Seven infants did not require noninvasive ventilation (NIV) by study completion. Eleven patients had stable or improved swa

matched on Quality of Life (keyword), quality of life (text)

Sanders JJ, Temin S, Ghoshal A, Alesi ER, Ali ZV, Chauhan C, Cleary JF, Epstein AS, Firn JI, Jones JA, Litzow MR, Lundquist D, Mardones MA, Nipp RD, Rabow MW, Rosa WE, Zimmermann C, Ferrell BR (2024)guidelineMEDLINE-indexed journal, not yet read by usJournal of clinical oncology : official journal of the American Society of Clinical Oncology203 citations

Palliative Care for Patients With Cancer: ASCO Guideline Update.

Purpose: To provide evidence-based guidance to oncology clinicians, patients, nonprofessional caregivers, and palliative care clinicians to update the 2016 ASCO guideline on the integration of palliative care into standard oncology for all patients diagnosed with cancer. Methods: ASCO convened an Expert Panel of medical, radiation, hematology-oncology, oncology nursing, palliative care, social work, ethics, advocacy, and psycho-oncology experts. The Panel conducted a literature search, including systematic reviews, meta-analyses, and randomized controlled trials published from 2015-2023. Outcomes of interest included quality of life (QOL), patient satisfaction, physical and psychological symptoms, survival, and caregiver burden. Expert Panel members used available evidence and informal consensus to develop evidence-based guideline recommendations. Results: The literature search identifie

matched on Quality of Life (mesh), quality of life (text)

Chey WD, Hashash JG, Manning L, Chang L (2022)guidelineMEDLINE-indexed journal, not yet read by usGastroenterology106 citations

AGA Clinical Practice Update on the Role of Diet in Irritable Bowel Syndrome: Expert Review.

Description: Irritable bowel syndrome (IBS) is a commonly diagnosed gastrointestinal disorder that can have a substantial impact on quality of life. Most patients with IBS associate their gastrointestinal symptoms with eating food. Mounting evidence supports dietary modifications, such as the low-fermentable oligo-, di-, and monosaccharides and polyols (FODMAP) diet, as a primary treatment for IBS symptoms. The aim of this American Gastroenterological Association (AGA) Clinical Practice Update (CPU) is to provide best practice advice statements, primarily to clinical gastroenterologists, covering the role of diet in IBS treatment. Methods: This expert review was commissioned and approved by the AGA CPU Committee and the AGA Governing Board to provide timely guidance on a topic of high clinical importance to the AGA membership, and underwent internal peer review by the CPU Committee and e

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Canadian Cardiovascular Society 2022 Guidelines for Peripheral Arterial Disease.

Patients with widespread atherosclerosis such as peripheral artery disease (PAD) have a high risk of cardiovascular and limb symptoms and complications, which affects their quality of life and longevity. Over the past 2 decades there have been substantial advances in diagnostics, pharmacotherapy, and interventions including endovascular and open surgical to aid in the management of PAD patients. To summarize the evidence regarding approaches to diagnosis, risk stratification, medical and intervention treatments for patients with PAD, guided by the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) framework, evidence was synthesized, and assessed for quality, and recommendations provided-categorized as weak or strong for each prespecified research question. Fifty-six recommendations were made, with 27% (15/56) graded as strong recommendations with high-quality ev

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International Exercise Recommendations in Older Adults (ICFSR): Expert Consensus Guidelines.

The human ageing process is universal, ubiquitous and inevitable. Every physiological function is being continuously diminished. There is a range between two distinct phenotypes of ageing, shaped by patterns of living - experiences and behaviours, and in particular by the presence or absence of physical activity (PA) and structured exercise (i.e., a sedentary lifestyle). Ageing and a sedentary lifestyle are associated with declines in muscle function and cardiorespiratory fitness, resulting in an impaired capacity to perform daily activities and maintain independent functioning. However, in the presence of adequate exercise/PA these changes in muscular and aerobic capacity with age are substantially attenuated. Additionally, both structured exercise and overall PA play important roles as preventive strategies for many chronic diseases, including cardiovascular disease, stroke, diabetes,

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National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2020 Highly morbid forms report.

Chronic graft-versus-host disease (GVHD) can be associated with significant morbidity, in part because of nonreversible fibrosis, which impacts physical functioning (eye, skin, lung manifestations) and mortality (lung, gastrointestinal manifestations). Progress in preventing severe morbidity and mortality associated with chronic GVHD is limited by a complex and incompletely understood disease biology and a lack of prognostic biomarkers. Likewise, treatment advances for highly morbid manifestations remain hindered by the absence of effective organ-specific approaches targeting "irreversible" fibrotic sequelae and difficulties in conducting clinical trials in a heterogeneous disease with small patient numbers. The purpose of this document is to identify current gaps, to outline a roadmap of research goals for highly morbid forms of chronic GVHD including advanced skin sclerosis, fasciitis,

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Responsible, Safe, and Effective Prescription of Opioids for Chronic Non-Cancer Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines.

Background: Opioid use, abuse, and adverse consequences, including death, have escalated at an alarming rate since the 1990s. In an attempt to control opioid abuse, numerous regulations and guidelines for responsible opioid prescribing have been developed by various organizations. However, the US opioid epidemic is continuing and drug dose deaths tripled during 1999 to 2015. Recent data show a continuing increase in deaths due to natural and semisynthetic opioids, a decline in methadone deaths, and an explosive increase in the rates of deaths involving other opioids, specifically heroin and illicit synthetic fentanyl. Contrary to scientific evidence of efficacy and negative recommendations, a significant proportion of physicians and patients (92%) believe that opioids reduce pain and a smaller proportion (57%) report better quality of life. In preparation of the current guidelines, we ha

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Garvey WT, Mechanick JI, Brett EM, Garber AJ, Hurley DL, Jastreboff AM, Nadolsky K, Pessah-Pollack R, Plodkowski R, Reviewers of the AACE/ACE Obesity Clinical Practice Guidelines (2016)guidelineMEDLINE-indexed journal, not yet read by usEndocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists1,258 citations

AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY COMPREHENSIVE CLINICAL PRACTICE GUIDELINES FOR MEDICAL CARE OF PATIENTS WITH OBESITY.

Objective: Development of these guidelines is mandated by the American Association of Clinical Endocrinologists (AACE) Board of Directors and the American College of Endocrinology (ACE) Board of Trustees and adheres to published AACE protocols for the standardized production of clinical practice guidelines (CPGs). Methods: Recommendations are based on diligent review of clinical evidence with transparent incorporation of subjective factors. Results: There are 9 broad clinical questions with 123 recommendation numbers that include 160 specific statements (85 [53.1%] strong [Grade A]; 48 [30.0%] intermediate [Grade B], and 11 [6.9%] weak [Grade C], with 16 [10.0%] based on expert opinion [Grade D]) that build a comprehensive medical care plan for obesity. There were 133 (83.1%) statements based on strong (best evidence level [BEL] 1 = 79 [49.4%]) or intermediate (BEL 2 = 54 [33.7%]) levels

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Andersen BL, DeRubeis RJ, Berman BS, Gruman J, Champion VL, Massie MJ, Holland JC, Partridge AH, Bak K, Somerfield MR, Rowland JH, American Society of Clinical Oncology (2014)guidelineMEDLINE-indexed journal, not yet read by usJournal of clinical oncology : official journal of the American Society of Clinical Oncology472 citations

Screening, assessment, and care of anxiety and depressive symptoms in adults with cancer: an American Society of Clinical Oncology guideline adaptation.

Purpose: A Pan-Canadian Practice Guideline on Screening, Assessment, and Care of Psychosocial Distress (Depression, Anxiety) in Adults With Cancer was identified for adaptation. Methods: American Society of Clinical Oncology (ASCO) has a policy and set of procedures for adapting clinical practice guidelines developed by other organizations. The guideline was reviewed for developmental rigor and content applicability. Results: On the basis of content review of the pan-Canadian guideline, the ASCO panel agreed that, in general, the recommendations were clear, thorough, based on the most relevant scientific evidence, and presented options that will be acceptable to patients. However, for some topics addressed in the pan-Canadian guideline, the ASCO panel formulated a set of adapted recommendations based on local context and practice beliefs of the ad hoc panel members. It is recommended tha

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ICUD-EAU International Consultation on Bladder Cancer 2012: Urinary diversion.

Context: A summary of the 2nd International Consultation on Bladder Cancer recommendations on the reconstructive options after radical cystectomy (RC), their outcomes, and their complications. Objective: To review the literature regarding indications, surgical details, postoperative care, complications, functional outcomes, as well as quality-of-life measures of patients with different forms of urinary diversion (UD). Evidence acquisition: An English-language literature review of data published between 1970 and 2012 on patients with UD following RC for bladder cancer was undertaken. No randomized controlled studies comparing conduit diversion with neobladder or continent cutaneous diversion have been performed. Consequently, almost all studies used in this report are of level 3 evidence. Therefore, the recommendations given here are grade C only, meaning expert opinion delivered without

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