InInshirahislamically integrated self-help
SearchSubjectsReadingLibraryIndexHealth

Subjects

Fear learning and extinction

How fear is learned, held and unlearned.

Everything below was reached through this subject, not through the words you typed. Every row states how it was reached.

Qurʾān

القرآن6 shown

Verses named for this subject by hand come first. The rest are found by the subject’s own Arabic and English senses and are shown as lexical matches, not as anchors anyone has confirmed.

Qur'ān 21:103Arabic sense: الفزع, فزع

لَا يَحۡزُنُهُمُ ٱلۡفَزَعُ ٱلۡأَكۡبَرُ وَتَتَلَقَّىٰهُمُ ٱلۡمَلَٰٓئِكَةُ هَٰذَا يَوۡمُكُمُ ٱلَّذِي كُنتُمۡ تُوعَدُونَ

They will have no fear of the great Terror: the angels will receive them with the words, ‘This is the Day you were promised!’

Qur'ān 114:4Arabic sense: الوسواس, وسواس

مِن شَرِّ ٱلۡوَسۡوَاسِ ٱلۡخَنَّاسِ

against the harm of the slinking whisperer––

Qur'ān 27:87Arabic sense: فزع

وَيَوۡمَ يُنفَخُ فِي ٱلصُّورِ فَفَزِعَ مَن فِي ٱلسَّمَٰوَٰتِ وَمَن فِي ٱلۡأَرۡضِ إِلَّا مَن شَآءَ ٱللَّهُۚ وَكُلٌّ أَتَوۡهُ دَٰخِرِينَ

On the Day the Trumpet sounds, everyone in heaven and on earth will be terrified- except such as God wills- and all will come to Him in utter humility

Qur'ān 27:89Arabic sense: فزع

مَن جَآءَ بِٱلۡحَسَنَةِ فَلَهُۥ خَيۡرࣱ مِّنۡهَا وَهُم مِّن فَزَعࣲ يَوۡمَئِذٍ ءَامِنُونَ

whoever comes with a good deed will be rewarded with something better, and be secure from the terrors of that Day

Qur'ān 34:23Arabic sense: فزع

وَلَا تَنفَعُ ٱلشَّفَٰعَةُ عِندَهُۥٓ إِلَّا لِمَنۡ أَذِنَ لَهُۥۚ حَتَّىٰٓ إِذَا فُزِّعَ عَن قُلُوبِهِمۡ قَالُواْ مَاذَا قَالَ رَبُّكُمۡۖ قَالُواْ ٱلۡحَقَّۖ وَهُوَ ٱلۡعَلِيُّ ٱلۡكَبِيرُ

Intercession will not work with Him, except by those to whom He gives permission.’ They will be asked, after the terror is lifted from their hearts [on the Day of Judgement], ‘What did your Lord speak?’ and they will answer, ‘The Truth. He is the Most High, the Most Great.’

Qur'ān 34:51Arabic sense: فزع

وَلَوۡ تَرَىٰٓ إِذۡ فَزِعُواْ فَلَا فَوۡتَ وَأُخِذُواْ مِن مَّكَانࣲ قَرِيبࣲ‏

[Prophet], if you could only see their terror! There will be no escape when they are seized from a nearby place

Tafsīr

التفسير6 shown

Commentary on the verses above, at most two editions per verse.

en-asbab-al-nuzul-by-al-wahidi on 21:103en-asbab-al-nuzul-by-al-wahidicommentary on an ayah this subject surfaced

The greatest terror shall not make them sorrow, and the angels will receive them: “This is the day that you were promised.” On the Day of Resurrection in the greatest gathering place and most tremendous courtyard, they will not hear from the angels the call “no good news” [25:22], nor the address, “Stand apart today, O offenders!” [36:59], nor the harsh call, “Slink into it, and do not talk to Me!” [23:108]. They will not hear the call of separation's pain, nor will they despair of mercy. Rather the angels will keep on coming, company after company, and they will give the good news: “This is the day that you were promised,” that is, “This is the day in which you have the promised reward.” Among them are those who will be received by the angels, and among them are those who will be addressed and made known by the King. God will say, “My servants, have you been yearning for Me?” He will sa

en-al-jalalayn on 21:103en-al-jalalayncommentary on an ayah this subject surfaced

The Supreme Terror — which is that a servant be ordered off to the Fire shall not grieve them and the angels shall receive them upon their exiting from their graves saying to them ‘This is your day the one which you were promised’ during the life of the world.

en-al-jalalayn on 114:4en-al-jalalayncommentary on an ayah this subject surfaced

from the evil of the slinking whisperer Satan — he is referred to by the name of the action waswasa on account of his repeated engaging in it — who slinks away and recoils from the heart whenever God is mentioned

en-tafisr-ibn-kathir on 114:4en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

Say: "I seek refuge with the Lord of An-Nas, (1)"The King of An-Nas, (2)"The God of An-Nas, (3)"From the evil of the whisperer who withdraws. (4)"Who whispers in the breasts of An-Nas. (5)"Of Jinn and An-Nas. (6) These are three attributes from the attributes of the Lord, the Mighty and Majestic. They are lordship, sovereignty and divinity. Thus, He is the Lord of everything, the King of everything and the God of everything. All things are created by Him, owned by Him, and subservient to Him. Therefore, He commands whoever is seeking protection to seek refuge with the One Who has these attributes from the evil of the whisperer who withdraws. This (the whisperer) is the devil that is assigned to man. For verily, there is not any of the Children of Adam except that he has a companion that beautifies wicked deeds for him. This devil will go to any lengths to confuse and confound him. The o

en-al-jalalayn on 27:87en-al-jalalayncommentary on an ayah this subject surfaced

And the day when the Trumpet will be blown the Horn will be blown the First Blast by the archangel Isrāfīl and whoever is in the heavens and the earth will be terrified that is a fright that brings about death — as is stated in another verse and whoever is in the heavens and whoever is in the earth will swoon Q. 3968 the past tense fazi‘a is used to express the fact that such events will have occurred; except whom God will namely Gabriel Michael Isrāfīl and the Angel of Death. According to Ibn ‘Abbās however these excepted individuals are the martyrs who are described as living with their Lord provided for by Him’ Q. 3169. And all kullun the nunation compensates for the missing genitive annexation in other words and every one of them after being brought back to life on the Day of Resurrection will come to Him read in the form of the verb atawhu or the active participle ātūhu in utter hum

en-tafisr-ibn-kathir on 27:87en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

And (remember) the Day on which the Trumpet (Şūr) will be blown – and all who are in the heavens and all who are on the earth, will be terrified except him whom Allah wills. And all shall come to Him, humbled (87)And you will see the mountains and think them solid, but they shall pass away as the passing away of the clouds. The work of Allah, Who perfected all things, verily, He is well-acquainted with what you do (88)Whoever brings a good deed, will have better than its worth; and they will be safe from the terror on that Day (89)And whoever brings an evil deed, they will be cast down on their faces in the Fire. (And it will be said to them) "Are you being recompensed anything except what you used to do? (90) The Terrors of the Day of Resurrection, the Rewards for Good Deeds and the Punishments for Evil Deeds Allah tells us about the terrors of the Day when the Şūr will be blown. The

Classical works

كتب التراث6 shown

Arabic originals, reached through the subject’s Arabic senses. Interpretive sources, never proof of a ruling.

ihya §6038ihyaArabic sense: الفزع, فزع

وجملة أدب المريض حسن الصبر وقلة الشكوى والضجر والفزع إلى الدعاء والتوكل بعد الدواء على خالق الدواء

mukhtasar-minhaj §897mukhtasar-minhajArabic sense: الفزع, فزع

وجملة آداب المريض: حسن الصبر، وقلة الشكوى والتضجر، والفزع إلى #

rawdat-muhibbin §149rawdat-muhibbinArabic sense: الفزع, فزع

أي لذلك الماء الذي غمر الأرض ومن عليها فصل وأما الوهل فهو بتحريك الهاء وأصله الفزع والروع يقال وهل يوهل وهو وهل ومستوهل قال القطامي يصف إبلا

rawdat-muhibbin §186rawdat-muhibbinArabic sense: الفزع, فزع

وأما اللوعة فقال في الصحاح لوعة الحب حرقته وقد لاعه الحب يلوعه والتاع فؤاده أي احترق من الشوق ومنه قولهم أتان لاعة الفؤاد إلى جحشها قال الأصمعي أي لائعة الفؤاد وهي التي كأنها ولهى من الفزع فصل

wabil-sayyib §407wabil-sayyibArabic sense: الفزع, فزع

| الفصل الرابع في اذكار الفزع في النوم والفكر

rawdat-muhibbin §2387rawdat-muhibbinArabic sense: الفزع, فزع

وقال أبو هريرة وابن عباس رضي الله عنهم خطب رسول الله صلى الله عليه وسلم قبل وفاته فقال في خطبته ومن قدر على امرأة أو جارية حراما فتركها مخافة من الله أمنه الله يوم الفزع الأكبر وحرمه على النار وأدخله الجنة

Research library

المكتبة البحثية1,226 works held

Peer-reviewed work held with its DOI and abstract, labelled with the study design its publication types report. None of it has been read or assessed, so nothing here may be cited as showing anything. Retracted work is held for the record but never listed; a review that a later version replaced is listed under its replacement and marked.

10.1016/j.biopsycho.2006.01.006Biological psychology (2006)MEDLINE-indexed journal, not yet read by us; matched on Conditioning, Classical, Extinction, Psychological, Fear, Amygdala, fear conditioning

Extending animal models of fear conditioning to humans.: A goal of fear and anxiety research is to understand how to treat the potentially devastating effects of anxiety disorders in humans. Much of this research utilizes classical fear conditioning, a simple paradigm that has been extensively investigated in animals, helping outline a brain circuitry thought to be responsible for the acquisition, expression and extinction of fear. The findings from non-human animal research have more recently been substantiated and extended in humans, using neuropsyc

10.1016/j.biopsycho.2006.01.008Biological psychology (2006)MEDLINE-indexed journal, not yet read by us; matched on Conditioning, Classical, Extinction, Psychological, Fear, Amygdala, fear extinction

Fear extinction in rats: implications for human brain imaging and anxiety disorders.: Fear extinction is the decrease in conditioned fear responses that normally occurs when a conditioned stimulus (CS) is repeatedly presented in the absence of the aversive unconditioned stimulus (US). Extinction does not erase the initial CS-US association, but is thought to form a new memory. After extinction training, extinction memory competes with conditioning memory for control of fear expression. Deficits in fear extinction are thought to contribute to post-traumatic stress disorder (PTSD).

10.1016/j.jpsychires.2008.01.017Journal of psychiatric research (2008)MEDLINE-indexed journal, not yet read by us; matched on Conditioning, Classical, Extinction, Psychological, Fear, fear conditioning, fear extinction

Presence and acquired origin of reduced recall for fear extinction in PTSD: results of a twin study.: Recall of fear extinction, which is thought to aid in recovery from a psychologically traumatic event, is hypothesized to be deficient in post-traumatic stress disorder (PTSD), but this has not yet been demonstrated in the laboratory, nor has its origin been investigated. To address these two issues, 14 pairs of monozygotic twins discordant for combat exposure, in 7 of which the combat-exposed twin had PTSD, underwent a two-day fear conditioning and extinction procedure. On Day 1, subjects viewe

10.1016/j.nlm.2016.05.007Neurobiology of learning and memory (2016)MEDLINE-indexed journal, not yet read by us; matched on Conditioning, Classical, Extinction, Psychological, Fear, fear conditioning, fear extinction

The effects of transcutaneous vagus nerve stimulation on conditioned fear extinction in humans.: A critical component of the treatment for anxiety disorders is the extinction of fear via repeated exposure to the feared stimulus. This process is strongly dependent on successful memory formation and consolidation. Stimulation of the vagus nerve enhances memory formation in both animals and humans. The objective of this study was to assess whether transcutaneous stimulation of the vagus nerve (tVNS) can accelerate extinction memory formation and retention in fear conditioned humans. To assess

10.1017/s0033291719001387Psychological medicine (2020)MEDLINE-indexed journal, not yet read by us; matched on Conditioning, Classical, Extinction, Psychological, Fear, fear conditioning

Neural signatures of conditioning, extinction learning, and extinction recall in posttraumatic stress disorder: a meta-analysis of functional magnetic resonance imaging studies.: Background: Establishing neurobiological markers of posttraumatic stress disorder (PTSD) is essential to aid in diagnosis and treatment development. Fear processing deficits are central to PTSD, and their neural signatures may be used as such markers. Methods: Here, we conducted a meta-analysis of seven Pavlovian fear conditioning fMRI studies comparing 156 patients with PTSD and 148 trauma-exposed healthy controls (TEHC) using seed-based d-mapping, to contrast neural correlates of experimental

10.1523/jneurosci.2713-18.2019The Journal of neuroscience : the official journal of the Society for Neuroscience (2019)MEDLINE-indexed journal, not yet read by us; matched on Conditioning, Classical, Extinction, Psychological, Fear, fear extinction

Role of Human Ventromedial Prefrontal Cortex in Learning and Recall of Enhanced Extinction.: Standard fear extinction relies on the ventromedial prefrontal cortex (vmPFC) to form a new memory given the omission of threat. Using fMRI in humans, we investigated whether replacing threat with novel neutral outcomes (instead of just omitting threat) facilitates extinction by engaging the vmPFC more effectively than standard extinction. Computational modeling of associability (indexing surprise strength and dynamically modulating learning rates) characterized skin conductance responses and vm

Research library, full list

826 to 850 of 1,226
Neimeyer RA, Currier JM, Coleman R, Tomer A, Samuel E (2011)MEDLINE-indexed journal, not yet read by usDeath studies35 citations

Confronting suffering and death at the end of life: the impact of religiosity, psychosocial factors, and life regret among hospice patients.

Although the role of spiritual, psychological, and social factors is receiving increasing attention in the end of life (EOL) context, we know far less than we need to about how these factors shape attitudes toward life and death in the face of looming loss. The present study begins to remedy these limitations by examining the relative impact of demographic characteristics, religious and psychosocial factors, and life regret on death attitudes and psychological wellbeing for a diverse group of 153 hospice patients. In addition to relying on well-validated quantitative assessments, qualitative interviews were conducted with participants to further illustrate the role of study factors in shaping various dimensions of death anxiety or acceptance and quality of life. In general, results showed that factors assessed in this investigation were significantly correlated with death attitudes and e

matched on Fear (mesh)

Pyszczynski T, Kesebir P (2011)MEDLINE-indexed journal, not yet read by usAnxiety, stress, and coping59 citations

Anxiety buffer disruption theory: a terror management account of posttraumatic stress disorder.

We present anxiety buffer disruption theory (ABDT) and provide a review of current evidence regarding the theory. ABDT is an application of terror management theory to explain diverse reactions to traumatic events and the onset and maintenance of posttraumatic stress disorder (PTSD). It posits that PTSD results from a disruption in one's anxiety-buffering mechanisms, which normally provide protection against anxiety in general and death anxiety in particular. The disruption of these mechanisms leaves the individual defenseless in the face of overwhelming anxiety, which leads to the major symptom clusters of PTSD: re-experiencing, hyper-arousal, and avoidance. According to ABDT, because of the disruption in their anxiety-buffering mechanisms, individuals with PTSD symptoms do not respond to mortality reminders in the defensive ways that psychologically healthier individuals do. We review

matched on Fear (mesh)

Alvarez RP, Chen G, Bodurka J, Kaplan R, Grillon C (2011)MEDLINE-indexed journal, not yet read by usNeuroImage246 citations

Phasic and sustained fear in humans elicits distinct patterns of brain activity.

Aversive events are typically more debilitating when they occur unpredictably than predictably. Studies in humans and animals indicate that predictable and unpredictable aversive events can induce phasic and sustained fear, respectively. Research in rodents suggests that anatomically related but distinct neural circuits may mediate phasic and sustained fear. We explored this issue in humans by examining threat predictability in three virtual reality contexts, one in which electric shocks were predictably signaled by a cue, a second in which shocks occurred unpredictably but never paired with a cue, and a third in which no shocks were delivered. Evidence of threat-induced phasic and sustained fear was presented using fear ratings and skin conductance. Utilizing recent advances in functional magnetic resonance imaging (fMRI), we were able to conduct whole-brain fMRI at relatively high spat

matched on Fear (mesh)

A selective role for dopamine in stimulus-reward learning.

Individuals make choices and prioritize goals using complex processes that assign value to rewards and associated stimuli. During Pavlovian learning, previously neutral stimuli that predict rewards can acquire motivational properties, becoming attractive and desirable incentive stimuli. However, whether a cue acts solely as a predictor of reward, or also serves as an incentive stimulus, differs between individuals. Thus, individuals vary in the degree to which cues bias choice and potentially promote maladaptive behaviour. Here we use rats that differ in the incentive motivational properties they attribute to food cues to probe the role of the neurotransmitter dopamine in stimulus-reward learning. We show that intact dopamine transmission is not required for all forms of learning in which reward cues become effective predictors. Rather, dopamine acts selectively in a form of stimulus-rew

matched on Conditioning, Classical (mesh)

van Wingen GA, Geuze E, Vermetten E, Fernández G (2011)MEDLINE-indexed journal, not yet read by usMolecular psychiatry122 citations

Perceived threat predicts the neural sequelae of combat stress.

Exposure to severe stressors increases the risk for psychiatric disorders in vulnerable individuals, but can lead to positive outcomes for others. However, it remains unknown how severe stress affects neural functioning in humans and what factors mediate individual differences in the neural sequelae of stress. The amygdala is a key brain region involved in threat detection and fear regulation, and previous animal studies have suggested that stress sensitizes amygdala responsivity and reduces its regulation by the prefrontal cortex. In this study, we used a prospective design to investigate the consequences of severe stress in soldiers before and after deployment to a combat zone. We found that combat stress increased amygdala and insula reactivity to biologically salient stimuli across the group of combat-exposed individuals. In contrast, its influence on amygdala coupling with the insul

matched on Fear (mesh)

Dunsmoor JE, Prince SE, Murty VP, Kragel PA, LaBar KS (2011)MEDLINE-indexed journal, not yet read by usNeuroImage155 citations

Neurobehavioral mechanisms of human fear generalization.

While much research has elucidated the neurobiology of fear learning, the neural systems supporting the generalization of learned fear are unknown. Using functional magnetic resonance imaging (fMRI), we show that regions involved in the acquisition of fear support the generalization of fear to stimuli that are similar to a learned threat, but vary in fear intensity value. Behaviorally, subjects retrospectively misidentified a learned threat as a more intense stimulus and expressed greater skin conductance responses (SCR) to generalized stimuli of high intensity. Brain activity related to intensity-based fear generalization was observed in the striatum, insula, thalamus/periacqueductal gray, and subgenual cingulate cortex. The psychophysiological expression of generalized fear correlated with amygdala activity, and connectivity between the amygdala and extrastriate visual cortex was corre

matched on Fear (mesh)

Hogarth L, Chase HW (2011)MEDLINE-indexed journal, not yet read by usJournal of experimental psychology. Animal behavior processes121 citations

Parallel goal-directed and habitual control of human drug-seeking: implications for dependence vulnerability.

Dual-process theories of learning and addiction propose that whereas freely elected drug/reward-seeking is goal-directed in being mediated by the expected value of the outcome, cue-elicited drug/reward-seeking is habitual in being elicited directly by antecedent stimuli, without retrieving a representation of outcome value. To substantiate this claim, the current study conducted a human devaluation-transfer procedure in which young adult smokers were first trained on a concurrent choice task to earn tobacco and chocolate points before one outcome was devalued by specific satiety or health warnings against consumption of that outcome. When choice was again tested in extinction, the selective reduction in performance of the action associated with the devalued outcome indicated that choice was controlled by an expectation of outcome value, that is, was goal-directed. Moreover, the presentat

matched on Extinction, Psychological (mesh)

Forbes EE, Phillips ML, Silk JS, Ryan ND, Dahl RE (2011)MEDLINE-indexed journal, not yet read by usDevelopmental neuropsychology100 citations

Neural systems of threat processing in adolescents: role of pubertal maturation and relation to measures of negative affect.

Adolescence ushers in dramatic social and affective changes and increased vulnerability for affective disorders. Yet, little is known about the effects of pubertal maturation on neural systems of social threat processing. We examined adolescents' brain function to social stimuli in relation to pubertal maturation, depressive symptoms, and real-world subjective negative affect. Compared with pre/early adolescents, mid/late adolescents exhibited less amygdala reactivity to emotionally neutral faces relative to non-face stimuli; less ventrolateral prefrontal cortex (VLPFC) reactivity to fearful faces relative to non-face stimuli, neutral faces, or angry faces; and more VLPFC reactivity to angry relative to neutral faces. Amygdala and VLPFC reactivity were correlated with negative affect and depressive symptoms. Threat-processing changes during puberty may facilitate changes in social behavi

matched on Fear (mesh)

Huys QJ, Cools R, Gölzer M, Friedel E, Heinz A, Dolan RJ, Dayan P (2011)MEDLINE-indexed journal, not yet read by usPLoS computational biology272 citations

Disentangling the roles of approach, activation and valence in instrumental and pavlovian responding.

Hard-wired, Pavlovian, responses elicited by predictions of rewards and punishments exert significant benevolent and malevolent influences over instrumentally-appropriate actions. These influences come in two main groups, defined along anatomical, pharmacological, behavioural and functional lines. Investigations of the influences have so far concentrated on the groups as a whole; here we take the critical step of looking inside each group, using a detailed reinforcement learning model to distinguish effects to do with value, specific actions, and general activation or inhibition. We show a high degree of sophistication in Pavlovian influences, with appetitive Pavlovian stimuli specifically promoting approach and inhibiting withdrawal, and aversive Pavlovian stimuli promoting withdrawal and inhibiting approach. These influences account for differences in the instrumental performance of ap

matched on Conditioning, Classical (mesh)

Carleton RN, Collimore KC, McCabe RE, Antony MM (2011)MEDLINE-indexed journal, not yet read by usJournal of anxiety disorders98 citations

Addressing revisions to the Brief Fear of Negative Evaluation scale: measuring fear of negative evaluation across anxiety and mood disorders.

The fear of negative evaluation (FNE) represents a fundamental component of social anxiety and social anxiety disorder (SAD) within modern cognitive-behavioral models (Clark & Wells, 1995; Rapee & Heimberg, 1997). As such, access to comprehensive psychometrics for measures of FNE is an important component of thorough clinical and research efforts. Among the most popular measures of FNE have been variations of the 12-item Brief Fear of Negative Evaluation (BFNE) scale (Leary, 1983). There are currently three versions of the BFNE based on two psychometric studies (i.e., two 8-item variants and a 12-item variant). There is still substantial debate regarding which of the three alternatives should be used by researchers and clinicians. Normative data for each of the three alternatives are not available across samples of individuals with diagnosed anxiety and mood disorders; moreover, there ha

matched on Fear (mesh)

Marx G, Witte N, Himmel W, Kühnel S, Simmenroth-Nayda A, Koschack J (2011)MEDLINE-indexed journal, not yet read by usPatient education and counseling16 citations

Accepting the unacceptable: medication adherence and different types of action patterns among patients with high blood pressure.

Objective: To gain deep insight into what it means for patients to live with drug-treated hypertension and to understand the implications for the doctors' influence on patients' adherence. Methods: Group discussions with 43 drug-treated hypertensive patients. Documentary method was used for interpretative analysis. Results: Four basic phenomena were identified (fear, ignorance, reluctance to discuss matters with the doctor, impact of illness experiences), which resulted in different types of action patterns: (1) the assertive actor, (2) the unconscious avoider, and (3) the inconsistent actor. The types of action patterns do not refer to any implications for adherence. The patients' action does not indicate their preferred model of doctor-patient interaction or their acceptance of taking medication. Conclusion: Adherence must not be seen as meaningless behaviour, which can simply be learn

matched on Fear (mesh)

App B, McIntosh DN, Reed CL, Hertenstein MJ (2011)MEDLINE-indexed journal, not yet read by usEmotion (Washington, D.C.)49 citations

Nonverbal channel use in communication of emotion: how may depend on why.

This study investigated the hypothesis that different emotions are most effectively conveyed through specific, nonverbal channels of communication: body, face, and touch. Experiment 1 assessed the production of emotion displays. Participants generated nonverbal displays of 11 emotions, with and without channel restrictions. For both actual production and stated preferences, participants favored the body for embarrassment, guilt, pride, and shame; the face for anger, disgust, fear, happiness, and sadness; and touch for love and sympathy. When restricted to a single channel, participants were most confident about their communication when production was limited to the emotion's preferred channel. Experiment 2 examined the reception or identification of emotion displays. Participants viewed videos of emotions communicated in unrestricted and restricted conditions and identified the communica

matched on Fear (mesh)

Wassum KM, Ostlund SB, Balleine BW, Maidment NT (2011)MEDLINE-indexed journal, not yet read by usLearning & memory (Cold Spring Harbor, N.Y.)110 citations

Differential dependence of Pavlovian incentive motivation and instrumental incentive learning processes on dopamine signaling.

Here we attempted to clarify the role of dopamine signaling in reward seeking. In Experiment 1, we assessed the effects of the dopamine D(1)/D(2) receptor antagonist flupenthixol (0.5 mg/kg i.p.) on Pavlovian incentive motivation and found that flupenthixol blocked the ability of a conditioned stimulus to enhance both goal approach and instrumental performance (Pavlovian-to-instrumental transfer). In Experiment 2 we assessed the effects of flupenthixol on reward palatability during post-training noncontingent re-exposure to the sucrose reward in either a control 3-h or novel 23-h food-deprived state. Flupenthixol, although effective in blocking the Pavlovian goal approach, was without effect on palatability or the increase in reward palatability induced by the upshift in motivational state. This noncontingent re-exposure provided an opportunity for instrumental incentive learning, the pr

matched on Conditioning, Classical (mesh)

Hacker K, Chu J, Leung C, Marra R, Pirie A, Brahimi M, English M, Beckmann J, Acevedo-Garcia D, Marlin RP (2011)MEDLINE-indexed journal, not yet read by usSocial science & medicine (1982)148 citations

The impact of Immigration and Customs Enforcement on immigrant health: perceptions of immigrants in Everett, Massachusetts, USA.

U.S. immigrants have faced a changing landscape with regard to immigration enforcement over the last two decades. Following the passage of the Illegal Immigration Reform and Immigrant Responsibility Act of 1996, and the creation of the Immigration and Customs Enforcement (ICE) agency after the attacks of September 11, 2001, detention and deportation activity increased substantially. As a result, immigrants today are experiencing heightened fear of profiling and deportation. Little research exists on how these activities affect the health and well-being of U.S. immigrant communities. This study sought to address this gap by using community-based participatory research to investigate the impact of enhanced immigration enforcement on immigrant health in Everett, Massachusetts, USA, a city with a large and diverse immigrant population. Community partners and researchers conducted 6 focus gro

matched on Fear (mesh)

De Jongh A, Schutjes M, Aartman IH (2011)MEDLINE-indexed journal, not yet read by usEuropean journal of oral sciences45 citations

A test of Berggren's model of dental fear and anxiety.

Berggren's (1984) model of dental fear and anxiety predicts that dentally anxious individuals postpone treatment, leading to a deteriorating dental state and subsequently to fear of negative evaluations in relation to their oral condition. The present study aimed to test one of the core assumptions of this model, namely that deterioration of dental health status would mediate the effects of avoidance of dental care on self-reported fear of negative evaluation. Participants were 73 patients (mean age 38.5 yr) meeting the diagnostic and statistical manual of mental disorders - 4th edn - Text Revision (DSM-IV-TR) criteria of dental phobia. Variables in the theoretical model were operationalized with multiple measures. A series of Sobel tests indicated that mediation was present for the relationship between years of avoidance and fear of negative self-evaluation when dental health status was

matched on Fear (mesh)

Shen H, Moussawi K, Zhou W, Toda S, Kalivas PW (2011)MEDLINE-indexed journal, not yet read by usProceedings of the National Academy of Sciences of the United States of America158 citations

Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors.

Persistent relapse to addictive drugs constitutes the most challenging problem in addiction therapy, and is linked to impaired prefrontal cortex regulation of motivated behaviors involving the nucleus accumbens. Using a rat model of heroin addiction, we show that relapse requires long-term potentiation (LTP)-like increases in synaptic strength in the prefrontal cortex projection to the nucleus accumbens. The increased synaptic strength was paralleled by dendritic spine enlargement in accumbens spiny neurons and required up-regulated surface expression of NMDA2b-containing receptors (NR2B). Accordingly, blocking NR2B before reinstating heroin-seeking prevented the induction of LTP-like changes in spine remodeling and synaptic strength, and inhibited heroin relapse. These data show that LTP-like neuroplasticity in prefrontal-accumbens synapses is initiated by NR2B stimulation and strongly

matched on Extinction, Psychological (mesh)

Grotle M, Foster NE, Dunn KM, Croft P (2010)MEDLINE-indexed journal, not yet read by usPain147 citations

Are prognostic indicators for poor outcome different for acute and chronic low back pain consulters in primary care?

Few studies have investigated whether prognostic indicators, which contribute to the transition from acute to chronic low back pain (LBP), are also those which contribute to continuing persistence of chronic LBP. We compared the contribution of physical, psychological and social indicators to predicting disability after one year between consulters with LBP of less than 3 months duration and more than 3 months duration. Data from two large prospective cohort studies of consecutive patients consulting with LBP in general practices were merged, providing complete data for 258 cases with acute/subacute LBP and 668 cases with chronic LBP at 12 months follow-up. There were significant differences between the two LBP groups in baseline characteristics and clinical course of disability, assessed by Roland Morris Disability Questionnaire, during the year of follow-up. Adjusted associations betwee

matched on Fear (mesh)

van de Ven N, Zeelenberg M, Pieters R (2010)MEDLINE-indexed journal, not yet read by usPsychological science16 citations

Warding off the evil eye: when the fear of being envied increases prosocial behavior.

The fear of being envied makes people act prosocially, in an attempt to ward off the potentially destructive effects of envy. In three experiments, people who were in a superior position and could be envied were more likely than control participants to give time-consuming advice to a potentially envious person or to help a potentially envious person pick up erasers she had accidentally scattered. However, helping behavior increased only if envy was likely to be malicious rather than benign. People who were better off did not increase their helping behavior toward people in general, but increased their helping only toward the potentially envious. This finding is consistent with the idea that the better off act more prosocially as an appeasement strategy. The fear of being envied serves useful group functions, because it triggers prosocial behavior that is likely to dampen the potentially

matched on Fear (mesh)

Foster S, Giles-Corti B, Knuiman M (2010)MEDLINE-indexed journal, not yet read by usHealth & place52 citations

Neighbourhood design and fear of crime: a social-ecological examination of the correlates of residents' fear in new suburban housing developments.

This study explored the relationship between neighbourhood design and residents' fear of crime in new suburban housing developments. Self-report and objective data were collected as part of the RESIDential Environments (RESIDE) Project. A neighbourhood form index based on the planning and land-use characteristics that draw people into public space, facilitate pedestrian movement and ensure the presence of 'territorial guardians' was developed for each participant (n=1059) from objective environmental data. With each additional index attribute, the odds of being fearful reduced (trend test p value=0.001), and this persisted even after progressive adjustment for demographics, victimisation, collective efficacy and perceived problems. The findings support the notion that a more walkable neighbourhood is also a place, where residents feel safer, and provides further evidence endorsing a shif

matched on Fear (mesh)

Nickerson A, Bryant RA, Steel Z, Silove D, Brooks R (2010)MEDLINE-indexed journal, not yet read by usJournal of psychiatric research75 citations

The impact of fear for family on mental health in a resettled Iraqi refugee community.

The current study aimed to evaluate the impact of fear for family remaining in the country of origin and under potential threat on the mental health of refugees. Adult Mandaean refugees (N=315) from Iraq, living in Sydney, Australia, were interviewed regarding fear for family in Iraq, fear of genocide, pre-migration trauma, post-migration living difficulties and psychological outcomes. Participants with immediate family in Iraq reported higher levels of symptoms of PTSD and depression, and greater mental health-related disability than those without family in Iraq. Intrusive fears about family independently predicted risk of PTSD, depression and disability after controlling for trauma exposure and current living difficulties. Threat to family members living in a context of ongoing threat predicted psychopathology and disability in Mandaean refugees. The effect of ongoing threat to family

matched on Fear (mesh)

Taubman-Ben-Ari O, Noy A (2010)MEDLINE-indexed journal, not yet read by usDeath studies4 citations

Self-consciousness and death cognitions from a terror management perspective.

Two studies explored the connection between self-consciousness and death cognitions. In Study 1 (n = 56), a positive association was found between accessibility of death-related thoughts and the ruminative dimension of self-consciousness. In Study 2 (n = 212), a mortality salience induction led to higher validation of cultural worldviews (a more severe perception of social transgressions) than a control group, but only among individuals with lower self-consciousness, whereas participants characterized by higher self-consciousness did not make increased use of this cultural anxiety buffer. Rather, their naturally heightened death awareness led them to react to social transgressors in a neutral condition in the way usually found only after a mortality salience induction. Gender could not alternatively account for these findings. The results are explained in terms of terror management theor

matched on Fear (mesh)

Williams MM, Scharff DP, Mathews KJ, Hoffsuemmer JS, Jackson P, Morris JC, Edwards DF (2010)MEDLINE-indexed journal, not yet read by usAlzheimer disease and associated disorders96 citations

Barriers and facilitators of African American participation in Alzheimer disease biomarker research.

African Americans experience a greater risk of Alzheimer disease (AD), but are underrepresented in AD research. Our study examined barriers and facilitators of AD research participation among African Americans. Investigators conducted 11 focus groups with African American participants (n=70) who discussed barriers and facilitators to AD research participation including lumbar puncture studies. The moderator and comoderator independently reviewed the transcripts, identified themes, and coded transcripts for analysis. Participants were predominately female (73%) with a mean age of 52 years (range 21 to 86 y). Concerns and attitudes were consistent across education, socioeconomic status, and sex. Mistrust was a fundamental reason for nonparticipation. Additional barriers included insufficient information dissemination in the African American community, inconvenience, and reputation of the r

matched on Fear (mesh)

Chen YM (2010)MEDLINE-indexed journal, not yet read by usJournal of clinical nursing100 citations

Perceived barriers to physical activity among older adults residing in long-term care institutions.

Aims: This study explored barriers that older residents of long-term care (LTC) institutions experience in regular physical activity participation. Background: Despite the benefits of physical activity, a large proportion of older adults still lead a sedentary lifestyle. Especially, for older residents of LTC institutions, ability and resources for practising physical activity are more restricted than community-dwelling older adults. They are very likely to encounter barriers to physical activity. However, little is known about what factors impede them from being physically active. To implement successful interventions, more information is needed to address barriers to regular physical activity. Design: A qualitative exploratory design. Methods: Purposive sampling was performed to recruit 90 older residents from six nursing homes in Taiwan. The interview transcripts were analysed by qual

matched on Fear (mesh)

Malti T, Gasser L, Gutzwiller-Helfenfinger E (2010)MEDLINE-indexed journal, not yet read by usThe British journal of developmental psychology32 citations

Children's interpretive understanding, moral judgments, and emotion attributions: relations to social behaviour.

The study investigated interpretive understanding, moral judgments, and emotion attributions in relation to social behaviour in a sample of 59 5-year-old, 123 7-year-old, and 130 9-year-old children. Interpretive understanding was assessed by two tasks measuring children's understanding of ambiguous situations. Moral judgments and emotion attributions were measured using two moral rule transgressions. Social behaviour was assessed using teachers' ratings of aggressive and prosocial behaviour. Aggressive behaviour was positively related to interpretive understanding and negatively related to moral reasoning. Prosocial behaviour was positively associated with attribution of fear. Moral judgments and emotion attributions were related, depending on age. Interpretive understanding was unrelated to moral judgments and emotion attributions. The findings are discussed in regard to the role of in

matched on Fear (mesh)

McMurtry MC, Chambers CT, McGrath PJ, Asp E (2010)MEDLINE-indexed journal, not yet read by usPain90 citations

When "don't worry" communicates fear: Children's perceptions of parental reassurance and distraction during a painful medical procedure.

Children's distress during painful medical procedures is strongly influenced by adult behavior. Adult reassurance (e.g., "it's okay") is associated with increased child distress whereas distraction is associated with increased child coping. It is unknown why reassurance shows this counterintuitive relationship with child distress. The present research investigated whether children perceive their parents as fearful when they reassure using complementary observational and experimental methodologies. One hundred children (40 boys, 60 girls) 5-10years old (M=8.02, SD=1.69) and their parents (86 mothers, 14 fathers) participated. First, spontaneous parent-child interactions during pediatric venipuncture were captured and used for a video-mediated recall task in which the children viewed instances of parental reassurance and distraction and rated their parents' fear and happiness. Second, the

matched on Fear (mesh)