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Infertility and pregnancy loss

Not conceiving, and losing a pregnancy or a newborn.

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Qurʾān

القرآن6 shown

Verses named for this subject by hand come first. The rest are found by the subject’s own Arabic and English senses and are shown as lexical matches, not as anchors anyone has confirmed.

Qur'ān 22:55Arabic sense: عقيم

وَلَا يَزَالُ ٱلَّذِينَ كَفَرُواْ فِي مِرۡيَةࣲ مِّنۡهُ حَتَّىٰ تَأۡتِيَهُمُ ٱلسَّاعَةُ بَغۡتَةً أَوۡ يَأۡتِيَهُمۡ عَذَابُ يَوۡمٍ عَقِيمٍ

The disbelievers will remain in doubt about it until the Hour suddenly overpowers them or until torment descends on them on a Day devoid of all hope

Qur'ān 42:50Arabic sense: عقيم

أَوۡ يُزَوِّجُهُمۡ ذُكۡرَانࣰ ا وَإِنَٰثࣰ اۖ وَيَجۡعَلُ مَن يَشَآءُ عَقِيمًاۚ إِنَّهُۥ عَلِيمࣱ قَدِيرࣱ‏

male to whoever He will, or both male and female, and He makes whoever He will barren: He is all knowing and all powerful

Qur'ān 51:29Arabic sense: عقيم

فَأَقۡبَلَتِ ٱمۡرَأَتُهُۥ فِي صَرَّةࣲ فَصَكَّتۡ وَجۡهَهَا وَقَالَتۡ عَجُوزٌ عَقِيمࣱ‏

His wife then entered with a loud cry, struck her face, and said, ‘A barren old woman?’

Qur'ān 51:41Arabic sense: عقيم

وَفِي عَادٍ إِذۡ أَرۡسَلۡنَا عَلَيۡهِمُ ٱلرِّيحَ ٱلۡعَقِيمَ

There is another sign in the Ad: We sent the life-destroying wind against them

Qur'ān 6:59Arabic sense: سقط

۞وَعِندَهُۥ مَفَاتِحُ ٱلۡغَيۡبِ لَا يَعۡلَمُهَآ إِلَّا هُوَۚ وَيَعۡلَمُ مَا فِي ٱلۡبَرِّ وَٱلۡبَحۡرِۚ وَمَا تَسۡقُطُ مِن وَرَقَةٍ إِلَّا يَعۡلَمُهَا وَلَا حَبَّةࣲ فِي ظُلُمَٰتِ ٱلۡأَرۡضِ وَلَا رَطۡبࣲ وَلَا يَابِسٍ إِلَّا فِي كِتَٰبࣲ مُّبِينࣲ‏

He has the keys to the unseen: no one knows them but Him. He knows all that is in the land and sea. No leaf falls without His knowledge, nor is there a single grain in the darkness of the earth, or anything, fresh or withered, that is not written in a clear Record

Qur'ān 7:149Arabic sense: سقط

وَلَمَّا سُقِطَ فِيٓ أَيۡدِيهِمۡ وَرَأَوۡاْ أَنَّهُمۡ قَدۡ ضَلُّواْ قَالُواْ لَئِن لَّمۡ يَرۡحَمۡنَا رَبُّنَا وَيَغۡفِرۡ لَنَا لَنَكُونَنَّ مِنَ ٱلۡخَٰسِرِينَ

When, with much wringing of hands, they perceived that they were doing wrong, they said, ‘If our Lord does not have mercy and forgive us, we shall be the losers.’

Tafsīr

التفسير6 shown

Commentary on the verses above, at most two editions per verse.

en-al-jalalayn on 22:55en-al-jalalayncommentary on an ayah this subject surfaced

And those who disbelieve will not cease to be in doubt of it that is the Qur’ān — because of what Satan had cast onto the tongue of the Prophet s and what had thereafter been nullified — until the Hour comes upon them unawares that is the Hour of their death or of resurrection comes upon them suddenly or there come upon them the chastisement of a day of desolation ‘aqīm namely the day of Badr which held nothing of good for disbelievers much like a sterile wind rīh ‘aqīm that bears no good; or it means the Day of Resurrection referred to as ‘desolate’ because thereafter there will be no more night.

en-al-jalalayn on 42:50en-al-jalalayncommentary on an ayah this subject surfaced

Or He combines them that is to say or He makes them males and females; and He makes whomever He will infertile such that she is unable to conceive or he cannot have a child. Surely He is Knower of what He creates Powerful in bringing about whatever He will.

en-al-jalalayn on 51:29en-al-jalalayncommentary on an ayah this subject surfaced

Then his wife Sarah came forward clamouring shouting fī sarratin is a circumstantial qualifier that is to say she came shouting and smote slapped her face and said ‘A barren old woman!’ who has never given birth to a child aged ninety-nine with Abraham being one hundred years old; or alternatively he was a hundred and twenty years old and she was ninety years old.

en-tafisr-ibn-kathir on 22:55en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

And those who disbelieved, will not cease to be in doubt about it until the Hour comes suddenly upon them, or there comes to them the torment of Yawm 'Aqim (55)The sovereignty on that Day will be that of Allah. He will judge between them. So those who believed and did righteous good deeds will be in Gardens of Delight (56)And those who disbelieved and denied Our Ayat, for them will be a humiliating torment (in Hell)(57) The Disbelievers will remain in Doubt and Confusion Allah tells us that the disbelievers will remain in doubt concerning this Qur'an. This was the view of Ibn Jurayj and was the view favored by Ibn Jarir. حَتَّىٰ تَأْتِيَهُمُ السَّاعَةُ بَغْتَةً (until the Hour comes suddenly upon them,) Mujahid said: "By surprise." Qatadah said: بَغْتَةً (suddenly) means, the command of Allah will catch the people unaware. Allah never seizes a people except when they are intoxicate

en-tafisr-ibn-kathir on 42:50en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

To Allah belongs the kingdom of the heavens and the earth. He creates what He wills. He bestows female upon whom He wills, and bestows male upon whom He wills (49)Or He bestows both males and females, and He renders barren whom He wills. Verily, He is the All-Knower and is Able (to do all things)(50) Allah tells us that He is the Creator, Sovereign and Controller of the heavens and the earth. Whatever he wills happens, and whatever He does not will does not happen. He gives to whomsoever He wills and withholds from whomsoever he wills; none can withhold what He gives, and none can give what He withholds, and He creates whatever He wills. يَهَبُ لِمَنْ يَشَاءُ إِنَاثًا (He bestows female upon whom He wills.) means, He gives them daughters only. Al-Baghawi said, "And among them (those who were given daughters only) was Lut, peace be upon him." وَيَهَبُ لِمَنْ يَشَاءُ الذُّكُورَ (and b

en-tafisr-ibn-kathir on 51:29en-tafisr-ibn-kathircommentary on an ayah this subject surfaced

Has the story reached you, of the honored guests of Ibrahim (24)When they came in to him and said: "Salaman!" He answered: "Salamun" and said: "You are a people unknown to me. (25)Then he turned to his household, and brought out a roasted calf (26)And placed it before them (saying): "Will you not eat? (27)Then he conceived fear of them (when they ate not). They said: "Fear not." And they gave him glad tidings of a son having knowledge (28)Then his wife came forward with a loud voice; she smote her face, and said: "A barren old woman! (29)They said: "Even so says your Lord. Verily, He is the All-Wise, the All-Knower. (30) The Guests of the Prophet Ibrahim We mentioned this story before in Surah Hud and Al-Hijr. Allah said, هَلْ أَتَاكَ حَدِيثُ ضَيْفِ إِبْرَاهِيمَ الْمُكْرَمِينَ (Has the story reached you, of the honored guests of Ibrahim), whom Ibrahim honored and who, فَقَالُوا سَلَ

Ḥadīth

الحديث6 shown

Sound narrations only, and never matched by text. A narration appears here because a compiler filed it under a chapter this subject maps to, or because someone read it and anchored it. Each row says which.

Jami' at-Tirmidhi 1081The Book On Marriagefiled here by the compiler

حَدَّثَنَا مَحْمُودُ بْنُ غَيْلاَنَ، حَدَّثَنَا أَبُو أَحْمَدَ الزُّبَيْرِيُّ، حَدَّثَنَا سُفْيَانُ، عَنِ الأَعْمَشِ، عَنْ عُمَارَةَ بْنِ عُمَيْرٍ، عَنْ عَبْدِ الرَّحْمَنِ بْنِ يَزِيدَ، عَنْ عَبْدِ اللَّهِ بْنِ مَسْعُودٍ، قَالَ خَرَجْنَا مَعَ النَّبِيِّ صلى الله عليه وسلم وَنَحْنُ شَبَابٌ لاَ نَقْدِرُ عَلَى شَيْءٍ فَقَالَ ‏ "‏ يَا مَعْشَرَ الشَّبَابِ عَلَيْكُمْ بِالْبَاءَةِ فَإِنَّهُ أَغَضُّ لِلْبَصَرِ وَأَحْصَنُ لِلْفَرْجِ فَمَنْ لَمْ يَسْتَطِعْ مِنْكُمُ الْبَاءَةَ فَعَلَيْهِ بِالصَّوْمِ فَإِنَّ الصَّوْمَ لَهُ وِجَاءٌ ‏"‏ ‏.‏ قَالَ أَبُو عِيسَى هَذَا حَدِيثٌ حَسَنٌ صَحِيحٌ ‏.‏ حَدَّثَنَا الْحَسَنُ بْنُ عَلِيٍّ الْخَلاَّلُ، حَدَّثَنَا عَبْدُ اللَّهِ بْنُ نُمَيْرٍ، حَدَّثَنَا الأَعْمَشُ، عَنْ عُمَارَةَ، نَحْوَهُ ‏.‏ قَالَ أَبُو عِيسَى وَقَدْ رَوَى غَيْرُ، وَاحِدٍ، عَنِ الأَعْمَشِ، بِهَذَا الإِسْنَادِ مِثْلَ هَذَا ‏.‏ وَرَوَى أَبُو مُعَاوِيَةَ، وَالْمُحَارِبِيُّ، عَنِ الأَعْمَشِ، عَنْ إِبْرَاهِيمَ، عَنْ عَلْقَمَةَ، عَنْ عَبْدِ اللَّهِ، عَنِ النَّبِيِّ صلى الله عليه وسلم نَحْوَهُ ‏.‏ قَالَ أَبُو عِيسَى كِلاَهُمَا صَحِيحٌ ‏.‏

Abdullah bin Mas'ud narrated:"We went with Allah's Messenger, while we were young men who had nothing. He said: 'O young men! You should marry, for indeed it helps in lowering the gaze and protecting the private parts. Whoever among you is not able to marry, then let him fast, for indeed fasting will diminish his sexual desire

Jami' at-Tirmidhi 1082The Book On Marriagefiled here by the compiler

حَدَّثَنَا أَبُو هِشَامٍ الرِّفَاعِيُّ، وَزَيْدُ بْنُ أَخْزَمَ الطَّائِيُّ، وَإِسْحَاقُ بْنُ إِبْرَاهِيمَ الْبَصْرِيُّ، قَالُوا حَدَّثَنَا مُعَاذُ بْنُ هِشَامٍ، عَنْ أَبِيهِ، عَنْ قَتَادَةَ، عَنِ الْحَسَنِ، عَنْ سَمُرَةَ، أَنَّ النَّبِيَّ صلى الله عليه وسلم نَهَى عَنِ التَّبَتُّلِ ‏.‏ قَالَ أَبُو عِيسَى وَزَادَ زَيْدُ بْنُ أَخْزَمَ فِي حَدِيثِهِ وَقَرَأَ قَتَادَةُ ‏:‏ ‏(‏ولقدْ أَرْسَلْنا رُسُلاً مِنْ قَبْلِكَ وَجَعَلْنَا لَهُمْ أَزْوَاجًا وَذُرِّيَّةً ‏)‏ ‏.‏ قَالَ وَفِي الْبَابِ عَنْ سَعْدٍ وَأَنَسِ بْنِ مَالِكٍ وَعَائِشَةَ وَابْنِ عَبَّاسٍ ‏.‏ قَالَ أَبُو عِيسَى حَدِيثُ سَمُرَةَ حَدِيثٌ حَسَنٌ غَرِيبٌ ‏.‏ وَرَوَى الأَشْعَثُ بْنُ عَبْدِ الْمَلِكِ هَذَا الْحَدِيثَ عَنِ الْحَسَنِ عَنْ سَعْدِ بْنِ هِشَامٍ عَنْ عَائِشَةَ عَنِ النَّبِيِّ صلى الله عليه وسلم نَحْوَهُ ‏.‏ وَيُقَالُ كِلاَ الْحَدِيثَيْنِ صَحِيحٌ ‏.‏

Qatadah narrated from Al-Hasan, from Samurah that:The Prophet prohibited celibacy

Sahih Muslim 916Prayer - Funeralsfiled here by the compiler

وَحَدَّثَنَاهُ قُتَيْبَةُ بْنُ سَعِيدٍ، حَدَّثَنَا عَبْدُ الْعَزِيزِ يَعْنِي الدَّرَاوَرْدِيَّ، ح وَحَدَّثَنَا أَبُو بَكْرِ بْنُ أَبِي شَيْبَةَ حَدَّثَنَا خَالِدُ بْنُ مَخْلَدٍ، حَدَّثَنَا سُلَيْمَانُ بْنُ بِلاَلٍ، جَمِيعًا بِهَذَا الإِسْنَادِ ‏.‏

This hadith has been narrated by Sulaiman b. Bilal with the same chain of transmitters

Sahih Muslim 917Prayer - Funeralsfiled here by the compiler

وَحَدَّثَنَا أَبُو بَكْرٍ، وَعُثْمَانُ، ابْنَا أَبِي شَيْبَةَ ح وَحَدَّثَنِي عَمْرٌو النَّاقِدُ، قَالُوا جَمِيعًا حَدَّثَنَا أَبُو خَالِدٍ الأَحْمَرُ، عَنْ يَزِيدَ بْنِ كَيْسَانَ، عَنْ أَبِي حَازِمٍ، عَنْ أَبِي هُرَيْرَةَ، قَالَ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏ "‏ لَقِّنُوا مَوْتَاكُمْ لاَ إِلَهَ إِلاَّ اللَّهُ ‏"‏ ‏.‏

Abu Huraira reported Allah's Messenger (ﷺ) as saying:Exhort to recite" There is no god but Allah" to those of you who are dying

Sunan Ibn Majah 1434Chapters Regarding Funeralsfiled here by the compiler

حَدَّثَنَا أَبُو بِشْرٍ، بَكْرُ بْنُ خَلَفٍ وَمُحَمَّدُ بْنُ بَشَّارٍ قَالاَ حَدَّثَنَا يَحْيَى بْنُ سَعِيدٍ، حَدَّثَنَا عَبْدُ الْحَمِيدِ بْنُ جَعْفَرٍ، عَنْ أَبِيهِ، عَنْ حَكِيمِ بْنِ أَفْلَحَ، عَنْ أَبِي مَسْعُودٍ، عَنِ النَّبِيِّ ـ صلى الله عليه وسلم ـ قَالَ ‏ "‏ لِلْمُسْلِمِ عَلَى الْمُسْلِمِ أَرْبَعُ خِلاَلٍ يُشَمِّتُهُ إِذَا عَطَسَ وَيُجِيبُهُ إِذَا دَعَاهُ وَيَشْهَدُهُ إِذَا مَاتَ وَيَعُودُهُ إِذَا مَرِضَ ‏"‏ ‏.‏

It was narrated from Abu Mas’ud that the Prophet (ﷺ) said:“The Muslim has four things due from the Muslim: He should answer [by saying Yarhamuk-Allah (may Allah have mercy on you)] to him if he sneezes (and says Al-Hamdulillah); he should accept his invitation if he invites him; he should attend his funeral if he dies; and he should visit him if he falls sick.”

Sunan Ibn Majah 1435Chapters Regarding Funeralsfiled here by the compiler

حَدَّثَنَا أَبُو بَكْرِ بْنُ أَبِي شَيْبَةَ، حَدَّثَنَا مُحَمَّدُ بْنُ بِشْرٍ، عَنْ مُحَمَّدِ بْنِ عَمْرٍو، عَنْ أَبِي سَلَمَةَ، عَنْ أَبِي هُرَيْرَةَ، قَالَ قَالَ رَسُولُ اللَّهِ ـ صلى الله عليه وسلم ـ ‏ "‏ خَمْسٌ مِنْ حَقِّ الْمُسْلِمِ عَلَى الْمُسْلِمِ رَدُّ التَّحِيَّةِ وَإِجَابَةُ الدَّعْوَةِ وَشُهُودُ الْجِنَازَةِ وَعِيَادَةُ الْمَرِيضِ وَتَشْمِيتُ الْعَاطِسِ إِذَا حَمِدَ اللَّهَ ‏"‏ ‏.‏

It was narrated from Abu Hurairah that the Messenger of Allah (ﷺ) said:“Five are the rights of the Muslim: Returning his greeting, accepting his invitation; attending his funeral; visiting the sick; and answering (saying Yarhamuk-Allah) to the one who sneezes, if he praises Allah (says Al-Hamdu Lillah).”

Classical works

كتب التراث6 shown

Arabic originals, reached through the subject’s Arabic senses. Interpretive sources, never proof of a ruling.

ighathat §560ighathatArabic sense: السقط, سقط

وقال سري السقطى : من ادعى باطن علم ينقضه ظاهر حكم فهو غالط

ihya §12697ihyaArabic sense: السقط, سقط

وقال بشر ما سألت أحدا قط شيئا إلا سريا السقطى لأنه قد صح عندي زهده في الدنيا فهو يفرح بخروج الشيء من يده ويتبرم ببقائه عنده فأكون عونا له على ما يحب

ihya §3441ihyaArabic sense: السقط, سقط

وقال سرى السقطي رحمه الله آه على لقمة ليس على الله فيها تبعة ولا لمخلوق فيها منة

ihya §4045ihyaArabic sense: السقط, سقط

فيكره ذلك والسقط ينبغي أن يسمى

ihya §6712ihyaArabic sense: السقط, سقط

وكان سرى السقطي يقول للصوفية إذا خرج الشتاء فقد خرج أذار وأورقت الأشجار وطاب الإنتشار فانتشروا

mukhtasar-minhaj §2742mukhtasar-minhajArabic sense: السقط, سقط

وقال السري السقطي: إنى لأنظر كل يوم إلى أنفى مخافة أن يكون قد اسود وجهي.

Research library

المكتبة البحثية627 works held

Peer-reviewed work held with its DOI and abstract, labelled with the study design its publication types report. None of it has been read or assessed, so nothing here may be cited as showing anything. Retracted work is held for the record but never listed; a review that a later version replaced is listed under its replacement and marked.

10.1016/j.fertnstert.2014.03.012Fertility and sterility (2014)MEDLINE-indexed journal, not yet read by us; matched on Fertilization in Vitro, Infertility, Female, Pregnancy Rate, Reproductive Techniques, Assisted, Fertility, Infertility, Male, infertility

A randomized clinical trial to determine optimal infertility treatment in older couples: the Forty and Over Treatment Trial (FORT-T).: Objective: To determine the optimal infertility therapy for women at the end of their reproductive potential. Design: Randomized clinical trial. Setting: Academic medical centers and private infertility center in a state with mandated insurance coverage. Patient(s): Couples with ≥ 6 months of unexplained infertility; female partner aged 38-42 years. Intervention(s): Randomized to treatment with two cycles of clomiphene citrate (CC) and intrauterine insemination (IUI), follicle stimulating hormon

10.1093/humrep/deae119Human reproduction (Oxford, England) (2024)MEDLINE-indexed journal, not yet read by us; matched on Infertility, Infertility, Female, Pregnancy Rate, Reproductive Techniques, Assisted, infertility, Pregnancy Rate

The clinical effectiveness of the Mind/Body Program for Infertility on wellbeing and assisted reproduction outcomes: a randomized controlled trial in search for active ingredients.: Study question: Does the Mind/Body Program for Infertility (MBPI) perform better, due to certain distinctive elements, than a partly matched support group in improving the wellbeing and medically assisted reproduction (MAR) outcomes of women with elevated distress levels in a clinical setting? Summary answer: While robust enhancements occurred in the wellbeing overall, the cognitive behavioural and formalized stress management elements of the MBPI allowed a significantly stronger improvement in

10.1186/s12884-019-2677-9BMC pregnancy and childbirth (2020)MEDLINE-indexed journal, not yet read by us; matched on Abortion, Spontaneous, Stillbirth, Perinatal Death, miscarriage, pregnancy loss

Men's grief following pregnancy loss and neonatal loss: a systematic review and emerging theoretical model.: Background: Emotional distress following pregnancy loss and neonatal loss is common, with enduring grief occurring for many parents. However, little is known about men's grief, since the majority of existing literature and subsequent bereavement care guidelines have focused on women. To develop a comprehensive understanding of men's grief, this systematic review sought to summarise and appraise the literature focusing on men's grief following pregnancy loss and neonatal loss. Methods: A systemat

10.1007/s10815-016-0690-8Journal of assisted reproduction and genetics (2016)MEDLINE-indexed journal, not yet read by us; matched on Infertility, Fertilization in Vitro, Pregnancy Rate, infertility, Pregnancy Rate

The effects of psychosocial interventions on the mental health, pregnancy rates, and marital function of infertile couples undergoing in vitro fertilization: a systematic review.: Purpose: The purpose of this study was to examine the effects of psychosocial interventions on the mental health, pregnancy rates, and marital function of infertile couples undergoing in vitro fertilization (IVF), as determined through RCT studies. Methods: Using the electronic databases PubMed, EMBase, Cochrane Library, CINAHL, PsycInfo, and CAJ, a systematic literature search was conducted in July 2015. MeSH terms, key words, and free words such as "infertility," "fertilization in vitro," "psy

10.1093/humrep/der246Human reproduction (Oxford, England) (2011)MEDLINE-indexed journal, not yet read by us; matched on Infertility, Fertilization in Vitro, Reproductive Techniques, Assisted, infertility

Stress, distress and outcome of assisted reproductive technology (ART): a meta-analysis.: Background: A number of studies have investigated the relationship between psychological factors such as stress and distress (measured as anxiety and depression) and outcomes of assisted reproductive technology (ART). The results, however, are inconsistent, and the strength of any associations remains to be clarified. We conducted a systematic review and meta-analysis of the results of studies reporting on the associations between stress, anxiety, and depression and ART outcomes. Methods: Prospe

10.1016/j.ajog.2019.06.051American journal of obstetrics and gynecology (2019)MEDLINE-indexed journal, not yet read by us; matched on Abortion, Spontaneous, Stillbirth, miscarriage

The impact of occupational shift work and working hours during pregnancy on health outcomes: a systematic review and meta-analysis.: Backgroud: An increasing number of original studies suggest that exposure to shift work and long working hours during pregnancy could be associated with the risk of adverse pregnancy outcomes, but the results remain conflicting and inconclusive. Objective: To examine the influences of shift work and longer working hours during pregnancy on maternal and fetal health outcomes. Data sources: Five electronic databases and 3 gray literature sources were searched up to March 15, 2019. Methods of study

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Fieldsend M, Smith JA (2020)MEDLINE-indexed journal, not yet read by usHuman reproduction (Oxford, England)9 citations

'Either stay grieving, or deal with it': the psychological impact of involuntary childlessness for women living in midlife.

Study question: What is it like for women to be involuntarily childless in midlife? Summary answer: Involuntarily childless women may be suffering from prolonged grief due to its ambiguous and intangible nature; however, they are also striving to find ways of dealing with their internal pain in order to live with their loss. What is known already: Many studies examining issues around human reproduction have tended to place childlessness in the realm of medicalised infertility and report generalised mental issues, such as depression and psychological distress, existing amongst women undergoing fertility treatments. Few studies, however, have focused on the individual with regard to the experiential significance of involuntary childlessness and living beyond the phase of trying for a baby. Study design, size, duration: A phenomenologically oriented person-centred qualitative design was use

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Kiesswetter M, Marsoner H, Luehwink A, Fistarol M, Mahlknecht A, Duschek S (2020)MEDLINE-indexed journal, not yet read by usBehavioral medicine (Washington, D.C.)36 citations

Impairments in life satisfaction in infertility: Associations with perceived stress, affectivity, partnership quality, social support and the desire to have a child.

Between 10% and 15% of couples in western society are affected by infertility. As a major source of psychological distress, infertility may be accompanied by a substantial decline in well-being, and mental symptoms including those of depression and anxiety. This study aimed to quantify impairments in life satisfaction in infertile couples and to identify psychosocial variables moderating these impairments. For this purpose, 228 infertile couples completed the Life Satisfaction Questionnaire (LSQ), Perceived Stress Questionnaire (PSQ), Positive and Negative Affect Schedule (PANAS), Penn State Worry Questionnaire (PSWQ), Partnership Questionnaire (PQ), Social Support Questionnaire, (SSQ) and Questionnaire on the Desire to Have a Child (QDC). Our sample scored below the norm of the general population on the LSQ sum score and various subscales, including those assessing social relationships,

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Top 10 priorities for future infertility research: an international consensus development study†  ‡.

Study question: Can the priorities for future research in infertility be identified? Summary answer: The top 10 research priorities for the four areas of male infertility, female and unexplained infertility, medically assisted reproduction and ethics, access and organization of care for people with fertility problems were identified. What is known already: Many fundamental questions regarding the prevention, management and consequences of infertility remain unanswered. This is a barrier to improving the care received by those people with fertility problems. Study design, size, duration: Potential research questions were collated from an initial international survey, a systematic review of clinical practice guidelines and Cochrane systematic reviews. A rationalized list of confirmed research uncertainties was prioritized in an interim international survey. Prioritized research uncertainti

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Nouman H, Benyamini Y (2019)MEDLINE-indexed journal, not yet read by usInternational journal of behavioral medicine10 citations

Religious Women's Coping with Infertility: Do Culturally Adapted Religious Coping Strategies Contribute to Well-Being and Health?

Background: Infertility is a source of stress, particularly in pronatalist societies in which a lifestyle without children is viewed as an unacceptable option. The present study examined the relationship between the use of culturally adapted religious coping strategies and emotional adjustment among women coping with fertility problems. Methods: This is a cross-sectional correlational study. One hundred and eighty-six religious Israeli women undergoing fertility treatment filled out questionnaires assessing their use of culturally adapted religious coping strategies and emotional adjustment (distress/well-being). Results: A path analysis showed that the culturally adapted religious coping strategies of seeking the support of Rabbis and seeking the support of God had a strong correlation with reduced psychological distress, but not with enhanced psychological well-being. Seeking approval

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Mahadeen A, Mansour A, Al-Halabi J, Al Habashneh S, Kenana AB (2018)MEDLINE-indexed journal, not yet read by usEastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit15 citations

Psychosocial wellbeing of infertile couples in Jordan.

Background: The psychological and social impact of infertility on married couples alerted researchers in developing countries to consequences of infertility and the need to not underestimate the problem. Aim: To examine the psychosocial wellbeing of infertile couples in Jordan. Methods: A cross-sectional descriptive correlational study design was used to collect data regarding depression, psychological distress, life satisfaction, coping, optimism and perceived social support from 248 infertile couples using a self-administered questionnaire. Data were collected from May to August 2016. Results: One hundred and sixty-four (66%) of the infertile couples had moderate to severe depression. Infertile couples had a high level of psychological distress, low level of life satisfaction, and yet a high level of optimism that the infertility is temporary. Participants had moderate ability to cope,

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Zurlo MC, Cattaneo Della Volta MF, Vallone F (2018)MEDLINE-indexed journal, not yet read by usQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation67 citations

Predictors of quality of life and psychological health in infertile couples: the moderating role of duration of infertility.

Purpose: To investigate the influence of individual characteristics (age, gender, educational level, coping strategies), perceived couple's Dyadic Adjustment, type of diagnosis and duration of infertility on self-reported quality of life (QoL) and psychological health in infertile couples, examining the potential moderating role of duration of infertility. Methods: A questionnaire composed by socio-demographics, Coping Orientations to Problem Experienced, Dyadic Adjustment Scale, FertiQoL, State-Trait Anxiety Inventory and Edinburgh Depression Scale was submitted to 206 couples undergoing infertility treatments. Results: Female patients perceived significantly lower levels of QoL and higher levels of Anxiety and Depression. High Educational level and Social Support Coping strategy were associated with higher QoL and psychological health only in female patients. Problem Solving Coping str

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Maroufizadeh S, Hosseini M, Rahimi Foroushani A, Omani-Samani R, Amini P (2018)MEDLINE-indexed journal, not yet read by usHealth and quality of life outcomes27 citations

The effect of depression on quality of life in infertile couples: an actor-partner interdependence model approach.

Background: Infertility can cause psychological distress and has a negative impact on quality of life (QoL). There have been no studies investigating the effect of depression on QoL in infertile couples at the dyadic level. This study aimed to investigate the effects of actors' and partners' depression on QoL in male-female dyads experiencing infertility using an innovative dyadic analysis approach, the Actor-Partner Interdependence Model (APIM). Methods: We conducted this cross-sectional study on 180 infertile couples in Tehran, Iran, during August-September 2017. Quality of life and depression were assessed using Fertility Quality of Life and Patient Health Questionnaire-9, respectively. Dyadic data were analyzed by the APIM approach. In this method, actor effect is the impact of a person's depression on his/her own QoL. Partner effect is the impact of a person's depression on his/her

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Yang B, Zhang J, Qi Y, Wang P, Jiang R, Li H (2017)MEDLINE-indexed journal, not yet read by usAmerican journal of men's health43 citations

Assessment on Occurrences of Depression and Anxiety and Associated Risk Factors in the Infertile Chinese Men.

The prevalence of depression and anxiety in the Chinese male population with infertility is still uncertain. The prevalence of depression, anxiety, and a combination of both psychological symptoms was 20.8%, 7.8%, and 15.4%, respectively in 771 infertile Chinese men in the current study by the Mental Health Inventory-5 and the State-Trait Anxiety Inventory-Short Form questionnaires. Differences in demographics (age, education, and income) had no noticeable impact on the development of psychological symptoms. Clinical factors such as concomitant disorders (varicocele, epididymal cyst, and erectile dysfunction) were identified as risk factors associated with depressive symptoms ( OR = 1.47; 95% CI [1.14, 1.90]; p < .001) and both depressive and anxiety symptoms ( OR = 1.56; 95% CI [1.17, 2.08]; p < .001). An infertility duration over 2 years was associated with a high risk of anxiety sympt

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Salih Joelsson L, Tydén T, Wanggren K, Georgakis MK, Stern J, Berglund A, Skalkidou A (2017)MEDLINE-indexed journal, not yet read by usEuropean psychiatry : the journal of the Association of European Psychiatrists35 citations

Anxiety and depression symptoms among sub-fertile women, women pregnant after infertility treatment, and naturally pregnant women.

Background: Infertility has been associated with psychological distress, but whether these symptoms persist after achieving pregnancy via assisted reproductive technology (ART) remains unclear. We compared the prevalence of anxiety and depressive symptoms between women seeking for infertility treatment and women who conceived after ART or naturally. Methods: Four hundred and sixty-eight sub-fertile non-pregnant women, 2972 naturally pregnant women and 143 women pregnant after ART completed a questionnaire in this cross-sectional study. The Anxiety subscale of the Hospital Anxiety and Depression Scale (HADS-A≥8) and Edinburgh Postnatal Depression Scale (EPDS≥12) were used for assessing anxiety and depressive symptoms, respectively. Multivariate Poisson regression models with robust variance were applied to explore associations with anxiety and depressive symptoms. Results: The prevalence

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Benyamini Y, Gozlan M, Weissman A (2017)MEDLINE-indexed journal, not yet read by usInternational journal of behavioral medicine16 citations

Normalization as a Strategy for Maintaining Quality of Life While Coping with Infertility in a Pronatalist Culture.

Purpose: Infertility could be highly stressful, particularly in a pronatalist culture. We aimed to develop the concept and a measure of normalization (maintaining normal life routines and feeling "normal") as a strategy that could enable women with infertility maintain their quality of life (QoL) while coping with this condition. We tested its associations with women's well-being, distress and QoL in Israel, where being childless is socially unacceptable and highly stigmatized. Methods: One-hundred and eighty Israeli women undergoing infertility treatment at a fertility community clinic filled in questionnaires assessing normalization-related coping strategies, QoL, and psychological adjustment (distress, wellbeing). Eight months later, 55 women conceived; 55 women who had not conceived completed a second questionnaire. Results: At baseline, normalization was related to higher QoL and be

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Neter E, Goren S (2017)MEDLINE-indexed journal, not yet read by usInternational journal of behavioral medicine10 citations

Infertility Centrality in the Woman's Identity and Goal Adjustment Predict Psychological Adjustment Among Women in Ongoing Fertility Treatments.

Purpose: Some of the women that go through repeated fertility treatments will not adjust well to the treatments and will experience increased distress. The present study examined how centrality of the fertility problem in the woman's identity and dispositional goal adjustment (disengagement and reengagement) are associated with the woman's psychological adjustment. These issues are examined in a context of a pro-natal society (Israel) where parenthood is a major life goal. Methods: One hundred ninety-three women in ongoing fertility treatments filled out questionnaires, and follow-up on their psychological well-being was carried out after 3 months (N = 130). Results: Women who perceived their fertility problem as more central to their identity experienced greater distress (β = 0.34, p < 0.01) and less well-being (β = - 0.31, p < 0.01). Concurrently, high ability for goal disengagement wa

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Alosaimi FD, Bukhari M, Altuwirqi M, Habous M, Madbouly K, Abotalib Z, Binsaleh S (2017)MEDLINE-indexed journal, not yet read by usHuman fertility (Cambridge, England)15 citations

Gender differences in perception of psychosocial distress and coping mechanisms among infertile men and women in Saudi Arabia.

The objective of the study was to evaluate the differences in psychosocial distress and coping mechanisms among infertile men and women in Saudi Arabia (SA). We performed a cross-sectional study of infertile patients (206 women and 200 men) attending infertility clinics in three referral hospitals in Riyadh, SA. A semi-structured questionnaire was developed to assess socio-demographic, clinical and psychosocial variables. Infertility-related psychosocial pressures were reported in 79 (39.7%) male and 97 (47.3%) female participants (p = 0.123). Males suffered more from intrusive questions and pressure to conceive, remarry or get divorced, while females were stressed more from psychological and emotional exhaustion, marital discord, attitudes of mothers-in-law or society, and persistent desire by the husband to have children. To cope with infertility, females engaged more in religious acti

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Gana K, Jakubowska S (2016)MEDLINE-indexed journal, not yet read by usJournal of health psychology49 citations

Relationship between infertility-related stress and emotional distress and marital satisfaction.

The aim of this study was to evaluate the predictive effects of infertility-related stress on psychological distress and marital satisfaction. Structural equation modeling was used to estimate a nonrecursive model hypothesizing the impact of infertility-related stress on both emotional distress and marital dissatisfaction, which were supposed to have a reciprocal influence on each other. The model was estimated using data from a sample of 150 infertile patients (78 males and 72 females). Findings confirmed the predictive effects of infertility-related stress on both emotional and marital distress. However, infertility-related stress was found to have more impact on emotional distress than on marital satisfaction.

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Chen D, Zhang JP, Jiang L, Liu H, Shu L, Zhang Q, Jiang L (2016)MEDLINE-indexed journal, not yet read by usApplied nursing research : ANR18 citations

Factors that influence in vitro fertilization treatment outcomes of Chinese men: A cross-sectional study.

Background: The thought of producing offspring has rooted in Chinese culture after thousands of years of feudal society. Infertility in men would bear significant psychological distress in this social environment. Purpose: In this study, we explored the association between the outcomes of IVF treatment and anxiety, depression, marital satisfaction, communication, sexual relationship and social support. Methods: A cross-sectional study was conducted. A total of 202 Chinese men who received IVF treatment for the first time were investigated using socio-demographic questionnaire, Self-Rating Anxiety Scale, Self-Rating Depression Scale, ENRICH Marital Inventory and Social Support Rating Scale on the first day of IVF treatment. Results: The overall prevalence of depression and anxiety was 49.1% and 27.2%, respectively. Subjects with IVF failure had higher levels of depression and anxiety, low

matched on Fertilization in Vitro (mesh), Infertility, Male (mesh), infertility (text)

A survey of fertility and sexual health following allogeneic haematopoietic stem cell transplantation in New South Wales, Australia.

Four hundred and twenty-one adult allogeneic haematopoietic stem cell transplant (HSCT) survivors participated in a cross-sectional study to assess sexual dysfunction and infertility post-transplant. Survey instruments included the Sydney Post-Blood and Marrow Transplant (BMT) Survey, Functional Assessment of Cancer Treatment (FACT) - BMT, the Depression, Anxiety, Stress Scales (DASS 21), the Chronic Graft-versus-Host Disease (cGVHD) Activity Assessment- Patient Self Report (Form B), the Lee cGVHD Symptom Scale and The Post-Traumatic Growth Inventory. Most HSCT survivors reported sexual difficulties (51% of males; 66% of females). Men reported erectile dysfunction (79%) and decreased libido (61·6%) and women reported loss of libido (83%), painful intercourse (73%) and less enjoyment of sex (68%). Women also commonly reported vaginal dryness (73%), vaginal narrowing (34%) and vaginal irri

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Read SC, Carrier ME, Boucher ME, Whitley R, Bond S, Zelkowitz P (2014)MEDLINE-indexed journal, not yet read by usPatient education and counseling51 citations

Psychosocial services for couples in infertility treatment: what do couples really want?

Objectives: To describe the psychosocial supports that infertile couples desire to help cope with infertility-related distress, which psychosocial services they sought, and the benefits and drawbacks of these services. Methods: Qualitative interview study with 32 heterosexual infertile couples seeking infertility treatment. Maximum variation sampling was used; data were analyzed using thematic analysis. Results: Most couples desired psychosocial support, but only half of the sample sought support. Some couples met with psychologists for help with relationship conflict and coping strategies. Participants suggested peer mentoring to fulfill needs for coping, shared experience, and guidance through the treatment process. Couples also desired written information about practical and emotional aspects of treatment. Negative attitudes toward psychological counseling and a lack of information ab

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Dooley M, Dineen T, Sarma K, Nolan A (2014)MEDLINE-indexed journal, not yet read by usHuman fertility (Cambridge, England)31 citations

The psychological impact of infertility and fertility treatment on the male partner.

Objectives: This paper reports the findings of two studies that examined factors predicting infertility distress in male partners within couples with an infertility diagnosis and where the couple was receiving fertility treatment. Design: A cross-sectional design was implemented using a questionnaire battery (The questionnaire battery comprised an inventory of four different standardised questionnaires compiled together into one booklet) compiled from earlier theory-building qualitative research conducted by the authors. Methods: Infertility related distress was examined in relation to a number of psychosocial variables including relationship dynamics, self-esteem, current mental health and attitudes towards idealised masculinity. The questionnaire battery was completed by 167 men undergoing or consulting for fertility treatment. Participants were recruited through Irish fertility clinic

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Read SC, Carrier ME, Whitley R, Gold I, Tulandi T, Zelkowitz P (2014)MEDLINE-indexed journal, not yet read by usJournal of alternative and complementary medicine (New York, N.Y.)18 citations

Complementary and alternative medicine use in infertility: cultural and religious influences in a multicultural Canadian setting.

Objectives: To explore the use of complementary and alternative medicine (CAM) for infertility in a multicultural healthcare setting and to compare Western and non-Western infertility patients' reasons for using CAM and the meanings they attribute to CAM use. Design: Qualitative semi-structured interviews using thematic analysis. Settings/location: Two infertility clinics in Montreal, Quebec, Canada. Participants: An ethnoculturally varied sample of 32 heterosexual infertile couples. Results: CAM used included lifestyle changes (e.g., changing diet, exercise), alternative medicine (e.g., acupuncture, herbal medicines), and religious methods (e.g., prayers, religious talismans). Patients expressed three attitudes toward CAM: desperate hope, casual optimism, and amused skepticism. PARTICIPANTS' CAM use was consistent with cultural traditions of health and fertility: Westerners relied prima

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Galhardo A, Pinto-Gouveia J, Cunha M, Matos M (2011)MEDLINE-indexed journal, not yet read by usHuman reproduction (Oxford, England)44 citations

The impact of shame and self-judgment on psychopathology in infertile patients.

Background: Little is known about psychological processes of infertile couples pursuing medical treatment in comparison with fertile couples and adoption candidates who also suffer from infertility but are not seeking medical help. This study aims to contribute to a better understanding of these individuals in terms of psychological processes (such as external shame, internal shame and self-judgment) and their association with psychopathology, also attending to gender differences. Methods: One hundred control couples without known fertility problems [fertile group (FG)], 100 couples with an infertility diagnosis and pursuing medical treatment [infertile group (IG)], and 40 couples with an infertility diagnosis who are applying for adoption [adoption group (AG)] completed the instruments: Beck Depression Inventory, Spielberger State-Trait Anxiety Inventory, Others as Shamer, Experience of

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Herrmann D, Scherg H, Verres R, von Hagens C, Strowitzki T, Wischmann T (2011)MEDLINE-indexed journal, not yet read by usJournal of assisted reproduction and genetics66 citations

Resilience in infertile couples acts as a protective factor against infertility-specific distress and impaired quality of life.

Objective: Our hypothesis was that resilience (=psychosocial stress-resistance) reduces infertility-specific distress and maintains quality of life of infertile couples. Methods: Questionnaire data of WHO Quality of Life assessment (WHOQOL; domains: 'physical', 'psychological', 'social relationships' and 'environment'), Fertility Problem Inventory (FPI; scales: 'social concern', 'sexual concern', 'relationship concern', 'rejection of childfree lifestyle' and 'need for parenthood'), Resilience Scale (RS), as well as sociographic and medical data were available for 199 infertile couples. Results: Age, medical diagnosis and 'intensity of desire for a child' had no influence on quality of life. High scores on 'suffering from childlessness' went along with less satisfaction on 'physical' and 'psychological' domains for the women only. For both partners, high scores on 'suffering from childles

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Dyer S, Lombard C, Van der Spuy Z (2009)MEDLINE-indexed journal, not yet read by usHuman reproduction (Oxford, England)32 citations

Psychological distress among men suffering from couple infertility in South Africa: a quantitative assessment.

Background: Recent years have seen a growing interest in the impact of infertility on reproductive health in developing countries. Most of the research which has addressed the psychosocial consequences of infertility in African countries has been qualitative in nature and focused on women. It was the aim of this study to assess psychological distress quantitatively in men suffering from couple infertility living in an urban community in South Africa. Methods: The Symptom Checklist-90-R, a standardized instrument for the measurement of current psychological symptom status, was administered to 120 men upon first presentation to a public health sector infertility clinic (study group) in a tertiary referral centre. The control group comprised 120 men who attended an antenatal clinic with their partner. All men may have previously fathered a child. Raw test scores were converted into standard

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Wischmann T, Scherg H, Strowitzki T, Verres R (2009)MEDLINE-indexed journal, not yet read by usHuman reproduction (Oxford, England)60 citations

Psychosocial characteristics of women and men attending infertility counselling.

Background: Little is known about the psychosocial characteristics of infertile couples seeking psychological help. This study describes couples attending infertility counselling. Methods: Questionnaires pertaining to socio-demographic factors, motives for wanting a child, lay aetiology of their infertility, dimensions of life and partnership satisfaction, and a complaints list were completed by 974 women and 906 men. Of those who indicated an openness to counselling, almost half actually attended infertility counselling, and two groups, 'no counselling' (358 women and 292 male partners) and 'taking up counselling' (275 women and 243 male partners), were therefore compared. Results: More couples with stressful life events were found in the counselling group. For women taking up counselling, psychological distress, in the form of suffering from childlessness and depression as well as subj

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Bayley TM, Slade P, Lashen H (2009)MEDLINE-indexed journal, not yet read by usHuman reproduction (Oxford, England)42 citations

Relationships between attachment, appraisal, coping and adjustment in men and women experiencing infertility concerns.

Background: Attachment style may influence distress and relationship satisfaction in infertile couples. Appraisal and coping have also been linked to adjustment to infertility and may be related to attachment patterns. The study examined these associations in men and women around the time of attending initial appointments at fertility clinics. Methods: Attachment, appraisal, coping, general well-being, infertility-related stress and relationship satisfaction questionnaires were completed by 98 women and 64 men. Data were analysed by gender comparisons, correlations and path analysis. Results: Attachment anxiety was associated with well-being in women via appraisal of infertility as a loss and use of self-blame and avoidance (SBA) coping. Attachment anxiety was also linked with infertility-related stress through SBA. In men, attachment anxiety was associated with well-being and infertilit

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Porter M, Bhattacharya S (2008)MEDLINE-indexed journal, not yet read by usHuman reproduction (Oxford, England)49 citations

Helping themselves to get pregnant: a qualitative longitudinal study on the information-seeking behaviour of infertile couples.

Background: Couples seeking infertility treatment are generally hungry for information about available therapeutic options and how to help themselves achieve pregnancy. This study examined couples' perceptions of the information available from various sources in the context of achieved pregnancy or continuing treatment. Methods: A 3 year prospective interview study started in April 2004, following couples undergoing infertility treatment at a tertiary fertility clinic at Aberdeen Maternity Hospital. Fifty-four couples were invited to participate. Up to three semi-structured interviews took place, and were analysed thematically using a variation of grounded theory. Results: Twenty-seven couples agreed to participate and of the 25 couples followed up, 11 were diagnosed with unexplained infertility. The age range of the women was 22-41 years. All hoped to be given information on helping the

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Slade P, O'Neill C, Simpson AJ, Lashen H (2007)MEDLINE-indexed journal, not yet read by usHuman reproduction (Oxford, England)180 citations

The relationship between perceived stigma, disclosure patterns, support and distress in new attendees at an infertility clinic.

Background: A model suggesting that high perception of stigma is associated with reduced disclosure to others, leading to lower social support and higher distress in new attendees at an infertility clinic is tested. Methods: Questionnaires measuring stigmatization (Stigma consciousness questionnaire), disclosure of fertility difficulties (Disclosure questionnaire), social support (Duke-UNC Functional Social Support Questionnaire) and fertility-related [Fertility Problem Inventory (FPI)] and generic distress [Hospital Anxiety and Depression Scale (HADS)] were completed by 87 women and 64 men. Data were analysed by gender comparisons, correlations and path analysis. Results: Women reported higher stigma and disclosure than men. For women, stigma and disclosure were unrelated but in men higher stigma was associated with lower disclosure. Perceptions of stigma were related to low social supp

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