Not conceiving, and losing a pregnancy or a newborn.
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426 to 450 of 627Alterations of sexual desire and satisfaction in male partners of infertile couples.
Objective: To clarify the state of sexual desire and satisfaction, with relevant parameters in men, of couples with infertility.
Design: Cross-sectional study.
Setting: University outpatient clinic.
Patient(s): Two hundred infertile couples referred to a reproductive health research clinic.
Intervention(s): Patients were investigated by a self-administered structured questionnaire about demographic data, infertility history, and several relevant psychological variables. In addition, clinical and andrological examinations were completed to find predictors for sexual state.
Main outcome measurement(s): Sexual desire and satisfaction status were scaled, and the relative factors were analyzed statistically.
Result(s): Subjects reported a reduction in sexual desire in 41.5% of cases and reduction of satisfaction in 52.5% compared with recalled sexual satisfaction before diagnosis of infertili…
matched on Infertility (mesh), infertility (text)
Psychological distress among women suffering from couple infertility in South Africa: a quantitative assessment.
Background: Infertility in Africa is commonly associated with negative psycho-social consequences. To date, most studies from African countries addressing these consequences have been qualitative in nature. The aim of this study was to assess psychological distress quantitatively among women suffering from couple infertility in an urban community in South Africa.
Methods: The Symptom Checklist-90-R (SCL-90-R), a standardized instrument for the measurement of current psychological symptom status, was administered to 120 women at the time of their first presentation to an infertility clinic in a tertiary referral centre. The control group comprised 120 women presenting to local family planning clinics. In addition, socio-demographic information and data pertaining to the prevalence of abuse was captured through a structured questionnaire designed for the purpose of this study.
Results: Wom…
matched on Infertility (mesh), infertility (text)
Infertility-related stress: A concept analysis.
Aim: To develop a clear definition of infertility-related stress using Rodgers' method of concept analysis.
Background: Infertility affects approximately 13% of women in the United States. Though poorly defined in the literature, previous studies suggest infertility-related stressors contribute to psychological distress.
Design: Rodgers' method of concept analysis guided the review, including sample and setting, literature search, and data analysis.
Data source: PubMed, CINAHL, and PsycINFO were searched for relevant literature.
Review methods: Following abstract, title, and text screenings, 21 articles were included and reported using the PRISMA-S checklist. Texts were analyzed and results informed the proposed definition of infertility-related stress.
Results: Antecedents included infertility, desire for children, and fear of the unknown. Attributes were identity crisis, social isolati…
matched on Infertility (keyword), Infertility, Female (mesh), infertility (text)
Lived experience of infertility among Hong Kong Chinese women.
Purpose: This study aims to explore and describe the phenomenon of women with infertility and to enhance understanding on how infertility affects their lives and the specific social consequence they encountered.
Method: A qualitative phenomenological design was adopted in this study. A total of 13 women who are infertile participated in the study. A snowball sampling method was adopted. Data were analysed through thematic analysis.
Results: Four themes emerged in the study, including (i) non-escapable cultural burden in Chinese family; (ii) psychological distress: isolation caused by envy; (iii) disappointment towards reproductive health services; and (iv) self-compassion and religion as coping strategies.
Conclusions: The causes of infertility are highly complex. Apart from medical conditions, many social conditions would also probably trigger the difficulty of conceiving. Health care p…
matched on Infertility (keyword), Infertility, Female (mesh), infertility (text)
Anxiety and depression among infertile women: a cross-sectional survey from Hungary.
Background: Infertility is often associated with a chronic state of stress which may manifest itself in anxiety-related and depressive symptoms. The aim of our study is to assess the psychological state of women with and without fertility problems, and to investigate the background factors of anxiety-related and depressive symptoms in women struggling with infertility.
Methods: Our study was conducted with the participation of 225 (134 primary infertile and 91 fertile) women, recruited in a clinical setting and online. We used the following questionnaires: Spielberger Trait Anxiety Inventory (STAI-T), Shortened Beck Depression Inventory (BDI) and Fertility Problem Inventory (FPI). We also interviewed our subjects on the presence of other sources of stress (the quality of the relationship with their mother, financial and illness-related stress), and we described sociodemographic and ferti…
matched on Infertility (keyword), Infertility, Female (mesh), infertility (text)
The infertility trap: how defeat and entrapment affect depressive symptoms.
Study question: Does the perception of failure without a solution or way forward of infertile couples have a mediator role between the importance couples attribute to parenthood and depressive symptoms?
Summary answer: The perception of failure without a solution or way forward, assessed by feelings of entrapment and defeat, mediates the effect of the importance of parenthood on depressive symptoms of infertile men and women.
What is known already: Research has documented that the heightened importance of parenthood affects infertile couples' adjustment to infertility and medical treatments. However, it remains unclear which psychological mechanisms and perceptions may underlie the association between having parenthood as a nuclear aspect of life and presenting depressive symptoms related to difficulties in accomplishing that important life goal. Although these links have been scantly ad…
matched on Infertility (keyword), Infertility, Female (mesh), infertility (text)
Social support, marital adjustment, and psychological distress among women with primary infertility in Pakistan.
This study aimed to identify prevalence rates of psychological distress among Pakistani women seeking help for primary infertility. The associations of social support, marital adjustment, and sociodemographic factors with psychological distress were also examined. A total of 177 women with primary infertility were interviewed from one hospital in Islamabad using a Self-Reporting Questionnaire, the Multidimensional Scale of Perceived Social Support, and the Locke-Wallace Marital Adjustment Test. The data were collected between November 2012 and March 2013. The prevalence of psychological distress was 37.3 percent. The results of the logistic regression suggested that marital adjustment and social support were significantly negatively associated with psychological distress in this sample. These associations were not confounded by any of the demographic variables controlled in the multivari…
matched on Infertility (keyword), Infertility, Female (mesh), infertility (text)
Psaros C, Kagan L, Shifren JL, Willett J, Jacquart J, Alert MD, Macklin EA, Styer AK, Denninger JW, LaRoche KL, Park ER (2015)MEDLINE-indexed journal, not yet read by usJournal of psychosomatic obstetrics and gynaecology15 citations Mind-body group treatment for women coping with infertility: a pilot study.
Objectives: To evaluate the feasibility of a 10-week mind-body intervention (MBI) for women coping with fertility challenges, examine the impact of an MBI on psychological distress and cortisol levels, and assess adherence to MBI skills 12-months after completion of the intervention.
Design: Prospective open pilot study of 51 women with infertility enrolled in a group MBI. Psychological variables and salivary cortisol levels were obtained pre- and post-intervention; a 12-month follow-up survey assessed MBI skill adherence. Participants completed practice logs throughout the intervention.
Results: Participants attended an average of eight sessions (SD = 2.0), and practiced mind-body techniques which elicited the relaxation response (RR) an average of 5.9 (SD = 0.8) days/week and 20.1 (SD = 9.9) min/day; 80% completed the post-treatment assessment. The intervention resulted in a significan…
matched on Infertility (keyword), Infertility, Female (mesh), infertility (text)
Communication, Training, and Debriefing After Stillbirth in U.S. Hospitals: A National Survey.
Background: Stillbirth is a devastating event for families as well as hospital staff. Hospital practices around internal and external staff communication, debriefing, and training are unknown. Methods: We systematically sampled U.S. hospitals that provide obstetrical care. Staff knowledgeable of bereavement care on labor and delivery were invited to participate in an anonymous survey linked to hospital descriptors. We evaluated stillbirth communication, debriefing, and training for staff. Results: We received 289 usable surveys from 429 eligible staff (67% response). Most (94%) noted hospitals' marked rooms housing bereaved families, but only a third (37%) reported a marker on the paper or electronic medical record. Half of the hospitals had no standard debriefings post-loss, and 38% reported no perinatal loss training for labor and delivery nurses. Conclusions: Hospitals have significan…
matched on Stillbirth (mesh), Perinatal Death (keyword)
Cassidy PR (2022)MEDLINE-indexed journal, not yet read by usJournal of perinatal medicine5 citations Beyond emotional support: predictors of satisfaction and perceived care quality following the death of a baby during pregnancy.
Objectives: To investigate which objective (actions/interventions) and subjective (perceptions of care quality) outcomes of care following stillbirth or termination of pregnancy predict perceived care quality.
Methods: A cross-sectional descriptive study using an anonymous online survey. The population was women who had experienced a stillbirth or termination of pregnancy from ≥16 weeks of gestation, in the Spanish health system. Multiple sequential regression analysis was used to identify predictors of perceived care quality (satisfaction, willingness to recommend, competence and ability to provide loss-focused care).
Results: Results from 610 women were analysed. A significant regression equation (p<0.001) was found in each of the objective only and objective-subjective models. In the case of overall care (satisfaction-recommend composite), 72.0% of variance (adj. R2) was explained. In…
matched on Stillbirth (mesh), Perinatal Death (keyword)
Assisted reproductive technology treatment and risk of breast cancer: a population-based cohort study.
Study question: Is there an increased risk of breast cancer among women after ART treatment including ovarian hormone stimulation?
Summary answer: The risk of breast cancer was slightly increased among women after ART treatment compared to age-matched, untreated women in the background population, and the risk was further increased among women initiating ART treatment when aged 40+ years.
What is known already: The majority of breast cancer cases are sensitive to oestrogen, and ovarian hormone stimulation has been suggested to increase the risk of breast cancer by influencing endogenous oestrogen levels. Previous studies on ART treatment and breast cancer have varied in their findings, but several studies have small sample sizes or lack follow-up time and/or confounder adjustment. Recent childbirth, nulliparity and higher socio-economic status are breast cancer risk factors and the latte…
matched on Infertility, Female (mesh), Reproductive Techniques, Assisted (mesh), infertility (text)
The pregnancy rate of infertile patients with proximal tubal obstruction 12 months following selective salpingography and tubal catheterization.
Objective: To assess the efficacy of selective salpingography (SSG) with additional tubal catheterization (TC) among infertile patients diagnosed with PTO and analysis of reproductive outcome.
Study design: Retrospective cohort study.
Results: Of a total of 399 tubes with confirmed proximal tubal occlusion, 383 successfully restored their patency resulting in 96 % technical success rate. Thirty-five percent of oviducts that had their patency restored was treated with SSG and 65% required additional TC. Reproductive outcomes at minimum 12 months following the treatment were collected by a telephone survey. 21/221 women were lost to follow up. Out of remaining 200 patients with at least one patent tube, 80 patients conceived which resulted in 40 % overall pregnancy rate.
Conclusion: Selective salpingography and tubal canalization offer patient-friendly, minimally invasive and cost-effectiv…
matched on Infertility, Female (mesh), Pregnancy Rate (mesh), infertility (text)
The impact of ART on union dissolution: a register-based study in Denmark 1994-2010.
Study question: Are couples initiating ART treatment at higher risk for future union dissolution compared to other couples?
Summary answer: There is no effect of ART treatments in future marital dissolution over a period of 16 years when adjusting for all confounders.
What is known already: Findings regarding marital stability and infertility treatments have been sparse and controversial. While there is data showing higher divorce rates among women who go through infertility treatments, there is also some evidence of this experience bringing couples closer by forcing them to communicate more and to deal with the surrounding stigma. Using a population-based study and couple-level data, we investigated the extent to which ART treatment increases the risk for divorce/marital dissolution during up to 16 years of follow-up.
Study design size, duration: Register-based national cohort study inc…
matched on Infertility, Female (mesh), Reproductive Techniques, Assisted (mesh), infertility (text)
Clomiphene citrate challenge test predicts outcome of intrauterine insemination in women aged under 37 years.
The clomiphene citrate challenge test is a tool to predict ovarian reserve and fertility. It has mainly been used as a predictor of success of IVF/intracytoplasmic sperm injection (ICSI) cycles. Infertile young women with diminished ovarian reserve have a worse prognosis than women with adequate ovarian reserve attempting IVF/ICSI cycles. Nothing is known regarding the outcome of young women with diminished ovarian reserve undergoing low-complexity assisted reproductive treatment such as ovulation induction plus intrauterine insemination (IUI). This study included all women under 37 years who consulted in the authors' centre between May 2004 and August 2005 who underwent ovulation induction and IUI. Ninety-six women younger than 37 years with adequate ovarian reserve, and 50 women with diminished ovarian reserve were found. The pregnancy rate and pregnancy rate per cycle in the adequate …
matched on Infertility, Female (mesh), Pregnancy Rate (mesh), infertility (text)
The Ethics of a Postmortem Testicular Harvest.
Background: Faith and religion are topics that are not routinely discussed or of much significance in the emergency department (ED). However, there are certain cases when faith or religion can cause certain ethical dilemmas for the physician, patient, or hospital. Understanding patients' beliefs affects our own medical decision-making and the ability to treat certain illnesses. Hospital policy or religious views of the hospital can affect patient management. Spirituality or religion in the ED will not be an issue with every patient; however, there are times where religious beliefs will be at the very center of an ED visit, as shown by this case report.
Case report: A 42-year-old man presented to the ED in cardiac arrest. Despite resuscitation and appropriate advanced cardiac life support, he was pronounced dead in the ED. The patient's wife stated they were trying to have a child and req…
matched on Fertilization in Vitro (mesh)
Hindi translation and validation of perinatal grief scale (short version): Assessing grief following stillbirth in bereaved mothers.
Background: Perinatal grief is the experience or emotions of parents following the loss of an infant by miscarriage, stillbirth, neonatal loss, or elective termination for fetal anomalies.
Aim: We aimed to translate and adapt the Perinatal Grief Scale (PGS) into Hindi and evaluate its psychometric properties in a sample of women who had recently experienced a stillbirth.
Method: The PGS was translated and adapted into Hindi following the process of translation and adaptation recommended by the World Health Organization. Internal consistency reliability was assessed by calculating Cronbach's alpha. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were carried out to assess discriminant validity and composite reliability. Additionally, the participants were assessed on four other questionnaires (State-Trait Anxiety Inventory, Edinburgh Postnatal Depression Scale, Ge…
matched on Stillbirth (keyword), miscarriage (text), pregnancy loss (text)
Changes in Importance of Motherhood Following Pregnancy Loss.
Pregnancy loss (i.e., miscarriage, stillbirth) is a relatively common and often traumatic experience. Although prior research has examined mental health consequences of pregnancy loss, to our knowledge, none have examined how the experience of pregnancy loss affects how women perceive or value the importance of motherhood. Using longitudinal data from the National Survey of Fertility Barriers, we applied change-score regression analysis to examine how a pregnancy loss that occurred between survey waves was associated with a change in importance of motherhood scores, controlling for sociodemographic and pregnancy-specific characteristics. We found that women who experienced a pregnancy loss reported an increase in importance of motherhood compared to women without a pregnancy loss. The findings suggest that an increase in the importance of motherhood following a pregnancy loss could be a …
matched on Stillbirth (keyword), miscarriage (text), pregnancy loss (text)
Finasteride-associated male infertility.
Objective: To describe a male patient with finasteride-associated infertility.
Design: Case report.
Setting: Tertiary-care clinic for male infertility.
Patient(s): A patient with azoospermia who had been taking finasteride (1-mg dose) for 1 year for androgenic alopecia. He had been diagnosed with oligospermia 5 years before.
Intervention(s): Discontinuation of finasteride.
Main outcome measure(s): Improvement of semen parameters.
Result(s): After cessation of finasteride, the patient's semen volume increased immediately, and sperm concentration was up to more than 10 × 10(6)/mL 16 weeks after stopping finasteride. He is now trying to achieve pregnancy by intrauterine insemination.
Conclusion(s): Cessation of finasteride improved spermatogenesis and allowed the couple to attempt less-invasive fertility therapy. In this case, the patient had impaired spermatogenesis before he started the d…
matched on Infertility, Male (mesh), infertility (text)
Parents and clinicians: partners in perinatal bereavement research -experiences from the International Stillbirth Alliance Conference 2017.
In recent years, there has been a global call to reduce the numbers of preventable stillbirths and increase public awareness about the incidence and impact of pregnancy loss. The lived experiences of bereaved parents have much to contribute to developing the research agenda and clinical care in pregnancy loss. The multidisciplinary Pregnancy Loss Research Group (PLRG) based at the INFANT Centre at University College Cork and Cork University Maternity Hospital, has an established practice of active engagement and participation of patient members. This partnership provided the catalyst to model a similar collaborative approach between clinicians, researchers and bereaved parents when the PLRG was successful in their bid to host the International Stillbirth Alliance (ISA) annual conference in 2017. Over 400 hundred delegates from around the globe attended the conference, of which one quarte…
matched on Stillbirth (keyword), pregnancy loss (text)
Discussing the possibility of fertility treatment being unsuccessful as part of routine care offered at clinics: patients' experiences, willingness, and preferences.
Study question: Are patients willing to discuss the possibility of treatment being unsuccessful as part of routine care offered at clinics, and what are the factors associated with this willingness?
Summary answer: Nine in every 10 patients are willing to discuss this possibility as part of routine care, with willingness being associated with higher perceived benefits, lower barriers, and stronger positive attitudes towards it.
What is known already: Fifty-eight percent of patients who complete up to three cycles of IVF/ICSI in the UK do not achieve a live birth. Offering psychosocial care for unsuccessful fertility treatment (PCUFT), defined as assistance and guidance on the implications of treatment being unsuccessful, could reduce the psychosocial distress patients experience when it happens, and promote positive adjustment to this loss. Research shows 56% of patients are willing to p…
matched on Fertilization in Vitro (mesh), Pregnancy Rate (mesh)
Quality-of-life predictors for men undergoing infertility treatment in Japan.
Aim: To dentify the predictors of the quality of life (QOL) of infertile men who are undergoing infertility treatments in Japan and to create a QOL prediction model, with the main variables aimed at providing more adequate support to male patients.
Methods: This cross-sectional study used the quantitative data that were collected from 321 returned self-report questionnaires that had been distributed to the men of 411 couples who were undergoing fertility treatment. The following four scales were used to measure the main outcomes: FertiQoL, psychological distress, spousal support, and workplace support. The data were analyzed by descriptive statistics, multiple regression analyses, and structural equation modeling.
Results: The number of returned questionnaires was 321 (78.1%). The QOL that was measured by FertiQoL was significantly lower in those men who were diagnosed with male factor i…
matched on Infertility (keyword), Infertility, Male (mesh), infertility (text)
Takaki J, Hibino Y (2014)MEDLINE-indexed journal, not yet read by usInternational journal of environmental research and public health15 citations Family-related opinions and stressful situations associated with psychological distress in women undergoing infertility treatment.
The purpose of this study is to investigate how family-related opinions and stressful situations are related to psychological distress in women undergoing infertility treatment. The subjects in this cross-sectional study were recruited from female patients undergoing infertility treatment (n = 2540) at 70 infertility treatment institutions in Japan. Because of non-participation or missing data, the number of subjects included in the analysis was 635 (response rate, 25.0%). The family-related opinions and stressful situations were evaluated using the original questions. Psychological distress was assessed using a self-report measure, the Kessler Six-question Psychological Distress Scale (K6). The K6 scores of the following participants were significantly (p < 0.05) and independently high: those with more frequent miscarriage/stillbirth/abortions, those with repeated miscarriages as the ca…
matched on Infertility, Female (mesh), miscarriage (text), infertility (text)
Impact of the COVID-19 Pandemic on the Lifestyles and Quality of Life of Women With Fertility Problems: A Cross-Sectional Study.
Background: The COVID-19 pandemic has implied worldwide the imposition of confinement measures and mobility restrictions, to a greater or lesser extent. It has also meant the closure of some public medical services such as reproductive care. This situation may have impacted the health-related behaviour and quality of life of women with fertility problems. Objective: The objective of this study was to analyse the effects of confinement and the suspension of reproductive medical care on the lifestyle (diet, physical exercise, and smoking habits), anxiety and depression, and quality of life of infertile women by comparing their pre- and post-confinement situations. Methods: We carried out a cross-sectional, internet-based study. Information was collected on these women's adherence to the Mediterranean diet (MEDAS questionnaire), physical exercise (IPAQ-SF), anxiety and depression (HADS), an…
matched on Infertility, Female (mesh), Fertility (mesh), infertility (text)
Review and follow-up of patients using a regional sperm cryopreservation service: ensuring that resources are targeted to those patients most in need.
Are all patients undergoing chemotherapy for long-term sperm banking at risk of permanent sterility? Male fertility is generally lower in men with cancer and all patient groups are at risk of azoospermia. Careful management is required to ensure that samples are not stored for excessively long periods should they not be required. A retrospective analysis of 1688 patient records and prospective recall of patients for semen testing were performed. Pre-therapy fertility was compared with a group of pre-vasectomy patients as a comparator. Those who fail to bank spermatozoa, rates of disposal of samples and the utilization in assisted reproduction were also examined. Sperm quality was poorest in testicular cancer (TC) patients followed by those with Hodgkin's lymphoma (HL) prior to treatment. Post-therapy data were available in 376 patients (42%). Sperm number was lowest (and azoospermia high…
matched on Reproductive Techniques, Assisted (mesh), Fertility (mesh), infertility (text)
Leon IG (2010)MEDLINE-indexed journal, not yet read by usThe journal of the American Academy of Psychoanalysis and Dynamic Psychiatry14 citations Understanding and treating infertility: psychoanalytic considerations.
This article describes how the intrapsychic, psychosocial, and social ramifications of infertility may be addressed when infertility patients present with distress at the psychotherapist's office. Self psychology provides a valuable framework for the therapist, given the profound and multiple narcissistic assaults on self-esteem, consolidation of identity, developmental aspirations, and other self attributes which infertility causes. The therapist's empathy becomes the primary tool of both understanding and alleviating suffering resulting from infertility. The current medical and interpersonal experiences of the infertile person must be part of the therapeutic process. A psychodynamic model of treatment is outlined which includes goals of reestablishing narcissistic equilibrium, diminishing internalized stigma, and ameliorating other adverse psychological consequences of infertility diag…
matched on Infertility, Female (mesh), Infertility, Male (mesh), infertility (text)