Rest and napping القيلولة

وَمِنۡ ءَايَٰتِهِۦ مَنَامُكُم بِٱلَّيۡلِ وَٱلنَّهَارِ وَٱبۡتِغَآؤُكُم مِّن فَضۡلِهِۦٓۚ إِنَّ فِي ذَٰلِكَ لَأٓيَٰتࣲ لِّقَوۡمࣲ يَسۡمَعُونَ

Among His signs are your sleep, by night and by day, and your seeking His bounty. There truly are signs in this for those who can hear

هُوَ ٱلَّذِي جَعَلَ لَكُمُ ٱلَّيۡلَ لِتَسۡكُنُواْ فِيهِ وَٱلنَّهَارَ مُبۡصِرًاۚ إِنَّ فِي ذَٰلِكَ لَأٓيَٰتࣲ لِّقَوۡمࣲ يَسۡمَعُونَ

It is He who made the night so that you can rest in it and the daylight so that you can see- there truly are signs in this for those who hear

وَمِن رَّحۡمَتِهِۦ جَعَلَ لَكُمُ ٱلَّيۡلَ وَٱلنَّهَارَ لِتَسۡكُنُواْ فِيهِ وَلِتَبۡتَغُواْ مِن فَضۡلِهِۦ وَلَعَلَّكُمۡ تَشۡكُرُونَ

In His mercy He has given you night and day, so that you may rest and seek His bounty and be grateful.’

وَمِنۡ ءَايَٰتِهِۦٓ أَنۡ خَلَقَ لَكُم مِّنۡ أَنفُسِكُمۡ أَزۡوَٰجࣰ ا لِّتَسۡكُنُوٓاْ إِلَيۡهَا وَجَعَلَ بَيۡنَكُم مَّوَدَّةࣰ وَرَحۡمَةًۚ إِنَّ فِي ذَٰلِكَ لَأٓيَٰتࣲ لِّقَوۡمࣲ يَتَفَكَّرُونَ

Another of His signs is that He created spouses from among yourselves for you to live with in tranquillity: He ordained love and kindness between you. There truly are signs in this for those who reflect

ٱللَّهُ ٱلَّذِي جَعَلَ لَكُمُ ٱلَّيۡلَ لِتَسۡكُنُواْ فِيهِ وَٱلنَّهَارَ مُبۡصِرًاۚ إِنَّ ٱللَّهَ لَذُو فَضۡلٍ عَلَى ٱلنَّاسِ وَلَٰكِنَّ أَكۡثَرَ ٱلنَّاسِ لَا يَشۡكُرُونَ

It is God who has given you the night in which to rest and the day in which to see. God is truly bountiful to people, but most people do not give thanks

And of His signs is your sleep by night and day by His will as a repose for you and your seeking during the day of His bounty in other words your going about freely in order to seek a living is by His will. Surely in that there are signs for people who listen listening in a way so as to be prompted to reflect and take heed.

And among His signs is the creation of the heavens and the earth, and the difference of your languages and colors. Verily, in that are indeed signs for men of sound knowledge (22)And among His signs is your sleep by night and by day, and your seeking His bounty. Verily, in that are indeed signs for a people who listen.) Allah sai (23) وَمِنْ آيَاتِهِ (And among His signs) indicating His magnificent power. خَلْقُ السَّمَاوَاتِ وَالْأَرْضِ (is the creation of the heavens and the earth,) The heavens with their vast height and brightness and beauty of the stars and planets, and the earth with its density and its mountains, valleys, seas, plains, animals and trees. وَاخْتِلَافُ أَلْسِنَتِكُمْ (and the difference of your languages) So, we see that some speak Arabic, and the Tatars have their own language, as do the Georgians, Romans, Franks, Berbers, Tou Couleurs (of Sudan), Ethiopians,

He it is Who made for you the night that you should rest therein and the day to see the attribution of sight ibsār to ‘the day’ is figurative since one is able to see during it. Surely in that are signs indications of His Oneness exalted be He for a folk who are able to hear hearing in such a way so as to reflect and be admonished.

And of His mercy exalted be He He has made for you night and day that you may rest therein in the night and that you may seek in the day of His bounty to earn your livelihood that perhaps you might give thanks’ for the grace of God during both of these times.

Do not grieve over their speech, for all power and honor belong to Allah. He is the All-Hearer, the All-Knower (65)Behold! Verily, to Allah belongs whosoever is in the heavens and whosoever is in the earth. And those who worship and invoke others besides Allah, in fact they follow not the partners, they follow only a conjecture and they do nothing but lie (66)He it is Who has appointed for you the night that you may rest therein, and the day to make things visible (to you). Verily, in this are Ayat for a people who listen (those who think deeply)(67) All Might and Honor is for Allah - He Alone has Full Authority within the Universe Allah said to His Messenger , وَلَا يَحْزُنكَ (Do not greive) because of the remarks of these idolators, and depend on Allah and ask for His help. Put your trust in Him. إِنَّ الْعِزَّةَ لِلَّهِ جَمِيعًا (For all power and honor belong to Allah.) All mig

Say: "Tell me! If Allah made the night continuous for you till the Day of Resurrection, which god besides Allah could bring you light? Will you not then hear? (71)Say: "Tell me! If Allah made the day continuous for you till the Day of Resurrection, which god besides Allah could bring you night wherein you rest? Will you not then see? (72)It is out of His mercy that He has made for you the night and the day that you may rest therein and that you may seek of His bounty – and in order that you may be grateful (73) Night and Day are among the Blessings of Allah and are Signs of Tawhid Allah reminds His servants of His favors towards them by subjugating for them the night and day, without which they could not survive. He explains that if He made the night continuous, lasting until the Day of Resurrection, that would be harmful for them and would cause boredom and stress. So He says: مَنْ إ

حَدَّثَنَا أَبُو نُعَيْمٍ، قَالَ حَدَّثَنَا سُفْيَانُ، عَنِ الأَسْوَدِ، قَالَ سَمِعْتُ جُنْدَبًا، يَقُولُ اشْتَكَى النَّبِيُّ صلى الله عليه وسلم فَلَمْ يَقُمْ لَيْلَةً أَوْ لَيْلَتَيْنِ‏.‏

Narrated Jundab:The Prophet (ﷺ) became sick and did not get up (for Tahajjud prayer) for a night or two

حَدَّثَنَا ابْنُ مُقَاتِلٍ، أَخْبَرَنَا عَبْدُ اللَّهِ، أَخْبَرَنَا مَعْمَرٌ، عَنِ الزُّهْرِيِّ، عَنْ هِنْدٍ بِنْتِ الْحَارِثِ، عَنْ أُمِّ سَلَمَةَ ـ رضى الله عنها ـ أَنَّ النَّبِيَّ صلى الله عليه وسلم اسْتَيْقَظَ لَيْلَةً فَقَالَ ‏ "‏ سُبْحَانَ اللَّهِ مَاذَا أُنْزِلَ اللَّيْلَةَ مِنَ الْفِتْنَةِ، مَاذَا أُنْزِلَ مِنَ الْخَزَائِنِ مَنْ يُوقِظُ صَوَاحِبَ الْحُجُرَاتِ، يَا رُبَّ كَاسِيَةٍ فِي الدُّنْيَا عَارِيَةٍ فِي الآخِرَةِ ‏"‏‏.‏

Narrated Um Salama:One night the Prophet (ﷺ) got up and said, "Subhan Allah! How many afflictions Allah has revealed tonight and how many treasures have been sent down (disclosed). Go and wake the sleeping lady occupants of these dwellings up (for prayers), perhaps a well dressed in this world may be naked in the Hereafter

أَخْبَرَنَا الْعَبَّاسُ بْنُ عَبْدِ الْعَظِيمِ، قَالَ حَدَّثَنَا عَبْدُ اللَّهِ بْنُ مُحَمَّدِ بْنِ أَسْمَاءَ، قَالَ حَدَّثَنَا جُوَيْرِيَةُ بْنُ أَسْمَاءَ، عَنِ الْوَلِيدِ بْنِ أَبِي هِشَامٍ، عَنْ نَافِعٍ، أَنَّ عَبْدَ اللَّهِ بْنَ عُمَرَ، قَالَ قَالَ رَسُولُ اللَّهِ صلى الله عليه وسلم ‏ "‏ صَلُّوا فِي بُيُوتِكُمْ وَلاَ تَتَّخِذُوهَا قُبُورًا ‏"‏ ‏.‏

It was narrated from Nafi' that Abdullah bin Umar said:"Pray in your houses and do not make them like graves

أَخْبَرَنَا أَحْمَدُ بْنُ سُلَيْمَانَ، قَالَ حَدَّثَنَا عَفَّانُ بْنُ مُسْلِمٍ، قَالَ حَدَّثَنَا وُهَيْبٌ، قَالَ سَمِعْتُ مُوسَى بْنَ عُقْبَةَ، قَالَ سَمِعْتُ أَبَا النَّضْرِ، يُحَدِّثُ عَنْ بُسْرِ بْنِ سَعِيدٍ، عَنْ زَيْدِ بْنِ ثَابِتٍ، أَنَّ النَّبِيَّ صلى الله عليه وسلم اتَّخَذَ حُجْرَةً فِي الْمَسْجِدِ مِنْ حَصِيرٍ فَصَلَّى رَسُولُ اللَّهِ صلى الله عليه وسلم فِيهَا لَيَالِيَ حَتَّى اجْتَمَعَ إِلَيْهِ النَّاسُ ثُمَّ فَقَدُوا صَوْتَهُ لَيْلَةً فَظَنُّوا أَنَّهُ نَائِمٌ فَجَعَلَ بَعْضُهُمْ يَتَنَحْنَحُ لِيَخْرُجَ إِلَيْهِمْ فَقَالَ ‏ "‏ مَا زَالَ بِكُمُ الَّذِي رَأَيْتُ مِنْ صُنْعِكُمْ حَتَّى خَشِيتُ أَنْ يُكْتَبَ عَلَيْكُمْ وَلَوْ كُتِبَ عَلَيْكُمْ مَا قُمْتُمْ بِهِ فَصَلُّوا أَيُّهَا النَّاسُ فِي بُيُوتِكُمْ فَإِنَّ أَفْضَلَ صَلاَةِ الْمَرْءِ فِي بَيْتِهِ إِلاَّ الصَّلاَةَ الْمَكْتُوبَةَ ‏"‏ ‏.‏

It was narrated from Zaid bin Thabit that :The Prophet (ﷺ) used some palm fiber mats to section off a small area in the masjid. And the Messenger of Allah (ﷺ) prayed in it for several nights until the people gathered around him. Then, one night they did not hear his voice, and they thought that he was sleeping, so they cleared their throats to make him come out to them. He said: 'You kept doing that until I feared that it would be made obligatory for you, and if it were made obligatory, you would not be able to do it. O people, pray in your houses, for the best prayer a person offers is in his house, apart from the prescribed (obligatory) prayers

والثاني: القيلولة، فإنها مما تعين على قيام الليل، كما يعين السحور على صيام النهار، فإن نام فليجتهد في الانتباه قبل الزوال بقدر الاستعداد للصلاة قبل دخول الوقت.

ومنها: أن لا يترك القيلولة بالنهار، فإنها تعين على قيام الليل.

اعلم أن قيام الليل عسير على الخلق إلا على من وفق للقيام بشروطه الميسرة له ظاهرا وباطنا فأما الظاهرة فأربعة أمور الأول أن لا يكثر الأكل فيكثر الشرب فيغلبه النوم ويثقل عليه القيام كان بعض الشيوخ يقف على المائدة كل ليلة ويقول معاشر المريدين لا تأكلوا كثيرا فتشربوا كثيرا فترقدوا كثيرا فتتحسروا عند الموت كثيرا وهذا هو الأصل الكبير وهو تخفيف المعدة عن ثقل الطعام الثاني أن لا يتعب نفسه بالنهار في الاعمال التي تعيا بها الجوارح وتضعف بها الأعصاب فإن ذلك ايضا مجلبة للنوم الثالث أن لا يترك القيلولة بالنهار فإنها سنة للاستعانة على قيام الليل + حديث الاستعانة بقيلولة النهار على قيام الليل أخرجه ابن ماجه من حديث ابن عباس وقد تقدم + الرابع أن لا يحتقب الأوزار بالنهار فإن ذلك مما يقسى القلب ويحول بينه وبين أسباب الرحمة قال رجل للحسن يا أبا سعيد إني أبيت معافى وأحب قيام الليل وأعد طهوري فما بالي لا أقوم فقال ذنوبك قيدتك وكان الحسن رحمه الله إذا دخل السوق فسمع لغطهم ولغوهم يقول أظن أن ليل هؤلاء ليل سوء فإ

الورد الثالث من ضحوة النهار إلى الزوال ونعني بالضحوة المنتصف وما قبله بقليل وإن كان بعد كل ثلاث ساعات أمر بصلاة فإذا انقضى ثلاث ساعات بعد الطلوع فعندها وقبل مضيها صلاة الضحى فإذا مضت ثلاث ساعات أخرى فالظهر فإذا مضت ثلاث ساعات أخرى فالعصر فإذا مضت ثلاث أخرى فالمغرب ومنزلة الضحى بين الزوال والطلوع كمنزلة العصر بين الزوال والغروب إلا أن الضحى لم تفرض لأنه وقت انكباب الناس على أشغالهم فخفف عنهم الوظيفة الرابعة في هذا الوقت الأقسام الأربعة وزيد أمران أحدهما الاشتغال بالكسب وتدبير المعيشة وحضور السوق فإن كان تاجرا فينبغي أن يتجر بصدق وأمانة وإن كان صاحب صناعة فبنصح وشفقة ولا ينسى ذكر الله تعالى في جميع أشغاله ويقتصر من الكسب على قدر حاجته ليومه مهما قدر على أن يكتسب في كل يوم لقوته فإذا حصل كفاية يومه فليرجع إلى بيت ربه وليتزود لآخرته فإن الحاجة إلى زاد الآخرة أشد والتمتع به أدوم فاشتغاله بكسبه أهم من طلب الزيادة على حاجة الوقت فقد قيل لا يوجد المؤمن إلا في ثلاث مواطن مسجد يعمره أو بيت يستره أ

قال الله تعالى @QB@ ومن آياته منامكم بالليل والنهار @QE@

معينة على ما شرع الله سبحانه له من النكاح وملك اليمين من إعفاف الرجل نفسه وأهله فلا تطمح نفسه إلى سواها من الحرام ويعفها فلا تطمح نفسها إلى غيره وكلما كانت المحبة بين الزوجين أتم وأقوى كان هذا المقصود أتم وأكمل قال تعالى : @QB@ هو الذي خلقكم من @QE@ @QB@ نفس واحدة وجعل منها زوجها ليسكن إليها @QE@ وقال : @QB@ ومن آياته أن خلق لكم من أنفسكم أزواجا لتسكنوا إليها وجعل بينكم مودة ورحمة @QE@

Slow-wave sleep during a brief nap is related to reduced cognitive deficits during sleep deprivation.: Sleeping for a short period (i.e. napping) may help mitigate impairments in cognitive processing caused by sleep deprivation, but there is limited research on effects of brief naps in particular. Here, we tested the effect of a brief nap opportunity (30- or 60-min) during a period of sleep deprivation on two cognitive processes with broad scope, placekeeping and vigilant attention. In the evening, participants (N = 280) completed a placekeeping task (UNRAVEL) and a vigilant attention task (Psych

The effects of a mid-day nap on the neurocognitive performance of first-year medical residents: a controlled interventional pilot study.: Purpose: Despite shorter duty hours, fatigue remains a problem among medical residents. The authors tested the effect of a short, mid-day nap on the cognitive functioning and alertness of first-year internal medicine (IM) residents during normal duty hours. Method: This was a controlled, interventional study performed between July 2008 and April 2010. The authors recruited a nap group of 18 residents and a rest (control) group of 11 residents. Investigators connected all participants to an ambul

Night shifts in interns: Effects of daytime napping on autonomic activity and cognitive function.: Objective: Night shifts have adverse cognitive outcomes that might be attenuated by daytime napping. The neurovisceral integration model suggests that resting vagally mediated heart rate variability (vmHRV) is linked with cognitive function. This study investigated the relationship between resting vmHRV and cognitive function after different nap durations in interns after shift work. Methods: A total of 105 interns were randomly allocated to one of three groups (non-nap, n = 35; 15-min nap, n =

Optimising sleep and performance during night float: A systematic review of evidence and implications for graduate medical education trainees.: Graduate medical education (GME) training commonly requires residents and fellows to engage in night float shift work. This review aims to assess the effectiveness of interventions for trainees when preparing for, completing, and recovering from working night float shifts. We reviewed all available studies published prior to September 2019 using PubMed, Scopus, CINAHL, the Cochrane library, PsycINFO, and Google Scholar databases. We included all original, primary research articles assessing eith

Effects of napping on sleepiness and sleep-related performance deficits in night-shift workers: a systematic review.: Night-shift workers are prone to sleep deprivation, misalignment of circadian rhythms, and subsequent sleepiness and sleep-related performance deficits. The purpose of this narrative systematic review is to critically review and synthesize the scientific literature regarding improvements in sleepiness and sleep-related performance deficits following planned naps taken during work-shift hours by night workers and to recommend directions for future research and practice. We conducted a literature

Is daytime napping an effective strategy to improve sport-related cognitive and physical performance and reduce fatigue? A systematic review and meta-analysis of randomised controlled trials.: Objective: To estimate the association between daytime napping and cognitive and physical sport performance and fatigue after normal sleep and partial sleep deprivation (less sleep duration than necessary). Design: Systematic review and meta-analysis. Data sources: The PubMed, Scopus, Web of Science, Cochrane Central, SportDiscus and PsycINFO databases. Eligibility criteria for selecting studies: Randomised controlled trials on the effect of daytime napping on sport performance and fatigue avail

Measurement of resident fatigue using rapid number naming.

Objective: Sleep deprivation has a negative effect on neurocognitive performance. The King-Devick test (KDT), which tests speed and accuracy of number-reading, requires integrity of saccades, visual processing, and cognition. This study investigated effects of sleep deprivation in on-call residents using KDT. Methods: A prospective cohort study was conducted among 80 residents. KDT was performed at the beginning and end of an overnight call shift for the residents in the experimental group. A control group was tested at the beginning of 2 consecutive day shifts. Estimates of hours of sleep, Karolinska Sleepiness Scale (KSS)(1 = extremely alert, 9 = extremely sleepy), and time and accuracy of KDT were recorded. Results: 42 residents were tested before and after overnight call shifts and 38 served as controls. Change in test time differed between the groups, with the experimental group per…

matched on Fatigue (mesh), Sleep Deprivation (mesh), Sleep Deprivation (keyword)

Development of a non-invasive polysomnography technique for dogs (Canis familiaris).

Recently dogs (Canis familiaris) have been demonstrated to be a promising model species for studying human behavior as they have adapted to the human niche and developed human-like socio-cognitive skills. Research on dog behavior, however, has so far almost exclusively focused on awake functioning. Here we present a self-developed non-invasive canine polysomnography method that can easily be applied to naive pet dogs. N=22 adult pet dogs (with their owners present) and N=12 adult humans participated in Study I. From these subjects, N=7 dogs returned on two more occasions for Study II. In Study I, we give a descriptive analysis of the sleep electroencephalogram of the dog and compare it to human data. In order to validate our canine polysomnography method in Study II, we compare the sleep macrostructure and the EEG spectrum of dogs after a behaviorally active day without sleep versus pass…

matched on Sleep (mesh), Sleep Deprivation (mesh), Sleep Deprivation (keyword)

Sleep selectively enhances memory expected to be of future relevance.

The brain encodes huge amounts of information, but only a small fraction is stored for a longer time. There is now compelling evidence that the long-term storage of memories preferentially occurs during sleep. However, the factors mediating the selectivity of sleep-associated memory consolidation are poorly understood. Here, we show that the mere expectancy that a memory will be used in a future test determines whether or not sleep significantly benefits consolidation of this memory. Human subjects learned declarative memories (word paired associates) before retention periods of sleep or wakefulness. Postlearning sleep compared with wakefulness produced a strong improvement at delayed retrieval only if the subjects had been informed about the retrieval test after the learning period. If they had not been informed, retrieval after retention sleep did not differ from that after the wake re…

matched on Wakefulness (mesh), Sleep (mesh)

Cognitive-emotional hyperarousal as a premorbid characteristic of individuals vulnerable to insomnia.

Objective: To examine whether cognitive-emotional hyperarousal is a premorbid characteristic of middle-aged and young good sleepers vulnerable to stress-related insomnia. Methods: Self-reported information was collected from two samples of 305 middle-aged and 196 young adults. From those adults, 149 middle-aged (50.34 +/- 4.47 years) and 85 young (20.19 +/- 1.31 years) good sleepers were selected for the present study. The Ford Insomnia Response to Stress Test (FIRST) was used to measure vulnerability to stress-related insomnia. Trait measures of personality, arousability, rumination, presleep arousal, and coping skills were entered as predictors in the linear regression models, at the same time controlling for gender, depression, and anxiety. Results: The regression models showed that arousability (beta = 0.546), neuroticism (beta = 0.413), perceived stress (beta = 0.375), and ruminatio…

matched on Wakefulness (mesh), Sleep (mesh)

Rumination predicts longer sleep onset latency after an acute psychosocial stressor.

Objectives: Rumination has been linked to self-reported sleep quality. However, whether rumination is related to an objective sleep parameter has not been tested. This study examined whether rumination predicts sleep onset latency (SOL) on the night after an acute psychosocial stressor. We hypothesized that those who ruminate (assessed with both trait and stressor-specific measures) would have longer SOL (assessed with objective and subjective methods). Methods: Seventy participants delivered a 5-minute speech in front of an evaluative panel during an afternoon laboratory session. Trait rumination was assessed before the stressor. Stressor-specific rumination was captured with the frequency of task-related thoughts participants experienced during a 10-minute rest period after the stressor. Participants wore actigraphs on their wrists on the night after the laboratory session to measure o…

matched on Wakefulness (mesh), Sleep (mesh)

Combining mindfulness meditation with cognitive-behavior therapy for insomnia: a treatment-development study.

This treatment-development study is a Stage I evaluation of an intervention that combines mindfulness meditation with cognitive-behavior therapy for insomnia (CBT-I). Thirty adults who met research diagnostic criteria for Psychophysiological Insomnia (Edinger et al., 2004) participated in a 6-week, multi-component group intervention using mindfulness meditation, sleep restriction, stimulus control, sleep education, and sleep hygiene. Sleep diaries and self-reported pre-sleep arousal were assessed weekly while secondary measures of insomnia severity, arousal, mindfulness skills, and daytime functioning were assessed at pre-treatment and post-treatment. Data collected on recruitment, retention, compliance, and satisfaction indicate that the treatment protocol is feasible to deliver and is acceptable for individuals seeking treatment for insomnia. The overall patterns of change with treatme…

matched on Wakefulness (mesh), Sleep (mesh)

Sleep after learning aids memory recall.

In recent years, the effect of sleep on memory consolidation has received considerable attention. In humans, these studies concentrated mainly on procedural types of memory, which are considered to be hippocampus-independent. Here, we show that sleep also has a persisting effect on hippocampus-dependent declarative memory. In two experiments, we examined high school students' ability to remember vocabulary. We show that declarative memory is enhanced when sleep follows within a few hours of learning, independent of time of day, and with equal amounts of interference during retention intervals. Sleep deprivation has a detrimental effect on memory, which was significant after a night of recovery sleep. Thus, fatigue accumulating during wake intervals could be ruled out as a confound.

matched on Wakefulness (mesh), Sleep (mesh)

Influence of flexibility and variability of working hours on health and well-being.

Flexible working hours can have several meanings and can be arranged in a number of ways to suit the worker and/or employer. Two aspects of "flexible" arrangement of working hours were considered: one more subjected to company control and decision (variability) and one more connected to individual discretion and autonomy (flexibility). The aim of the study was to analyze these two dimensions in relation to health and well-being, taking into consideration the interaction with some relevant background variables related to demographics plus working and social conditions. The dataset of the Third European Survey on working conditions, conducted in 2000 and involving 21,505 workers, was used. Nineteen health disorders and four psycho-social conditions were tested by means of multiple logistic regression analysis, in which mutually adjusted odds ratios were calculated for age, gender, marital …

matched on Work Schedule Tolerance (mesh), Fatigue (mesh)

Severe decrements in cognition function and mood induced by sleep loss, heat, dehydration, and undernutrition during simulated combat.

Background: Military exercises generate high levels of stress to simulate combat, providing a unique opportunity to examine cognitive and physiologic responses of normal humans to acute stress. Methods: Cognitive and physiologic markers of stress were evaluated before, during, and after an intense training exercise conducted for 53 hours in the heat. Cognitive performance, mood, physical activity, sleep, body composition, hydration, and saliva cortisol, testosterone, and melatonin were assessed. Volunteers were 31 male U.S. Army officers from an elite unit, aged 31.6 +/- .4 years. Results: Wrist activity monitors documented that soldiers slept only 3.0 +/- .3 hours during the exercise and were active throughout. Volunteers lost 4.1 +/- .2 kg (p < .001) of weight, predominately water (3.1 +/- .3 L) (p < .001). Substantial degradation in cognitive function, assessed with computerized tests…

matched on Work Schedule Tolerance (mesh), Sleep Deprivation (mesh)

Sleep-dependent motor memory plasticity in the human brain.

Growing evidence indicates a role for sleep in off-line memory processing, specifically in post-training consolidation. In humans, sleep has been shown to trigger overnight learning on a motor-sequence memory task, while equivalent waking periods produce no such improvement. But while the behavioral characteristics of sleep-dependent motor learning become increasingly well characterized, the underlying neural basis remains unknown. Here we present functional magnetic resonance imaging data demonstrating a change in the representation of a motor memory after a night of sleep. Subjects trained on a motor-skill memory and 12 hours later, after either sleep or wake, were retested during functional magnetic resonance imaging. Following sleep relative to wake, regions of increased activation were expressed in the right primary motor cortex, medial prefrontal lobe, hippocampus and left cerebell…

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Effects of onabotulinumtoxinA treatment for chronic migraine on common comorbidities including depression and anxiety.

Objective: To assess the effects of onabotulinumtoxinA treatment for chronic migraine (CM) on comorbid symptoms of depression, anxiety, fatigue and poor sleep quality. Methods: The Chronic Migraine OnabotulinuMtoxinA Prolonged Efficacy open-Label (COMPEL) study is a multicentre, open-label, prospective study assessing the long-term safety and efficacy of onabotulinumtoxinA 155 U over nine treatments (108 weeks) in adults with CM. The Patient Health Questionnaire (PHQ-9) and Generalised Anxiety Disorder (GAD-7) scales were used to assess the effects of onabotulinumtoxinA on comorbid symptoms of depression and anxiety, respectively. A clinically meaningful improvement was assessed by the percentage of patients experiencing a ≥1 severity category reduction in PHQ-9 and GAD-7. The effects of onabotulinumtoxinA on associated sleep quality and fatigue were assessed using the Pittsburgh Sleep Q…

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Improving fatigue risk management in healthcare: A systematic scoping review of sleep-related/fatigue-management interventions for nurses and midwives.

Background: Nurses and midwives make up almost 50% of the global healthcare shift working workforce. Shift work interferes with sleep and causes fatigue with adverse effects for nurses' and midwives' health, as well as on patient safety and care. Where other safety-critical sectors have developed Fatigue Risk Management Systems, healthcare is behind the curve; with published literature only focussing on the evaluation of discreet sleep-related/fatigue-management interventions. Little is known, however, about which interventions have been evaluated for nurses and midwives. Our review is a critical first step to building the evidence-base for healthcare organisations seeking to address this important operational issue. Objectives: We address two questions: (1) what sleep-related/fatigue-management interventions have been assessed in nurses and midwives and what is their evidence-base? and …

matched on napping (text), nap (text), Fatigue (mesh), Sleep (keyword)

How sleep and wakefulness influence circadian rhythmicity: effects of insufficient and mistimed sleep on the animal and human transcriptome.

The mammalian circadian system is a multi-oscillator, hierarchically organised system where a central pacemaker synchronises behavioural, physiological and gene expression rhythms in peripheral tissues. Epidemiological studies show that disruption of this internal synchronisation by short sleep and shift work is associated with adverse health outcomes through mechanisms that remain to be elucidated. Here, we review recent animal and human studies demonstrating the profound effects of insufficient and mistimed sleep on the rhythms of gene expression in central and peripheral tissues. In mice, sleep restriction leads to an ~80% reduction in circadian transcripts in the brain and profound disruption of the liver transcriptome. In humans, sleep restriction leads to a 1.9% reduction in circadian transcripts in whole blood, and when sleep is displaced to the daytime, 97% of rhythmic genes beco…

matched on Wakefulness (mesh), Sleep (mesh), Sleep Deprivation (mesh), Sleep Deprivation (keyword)

Sleep restriction therapy for insomnia is associated with reduced objective total sleep time, increased daytime somnolence, and objectively impaired vigilance: implications for the clinical management of insomnia disorder.

Study objectives: To investigate whether sleep restriction therapy (SRT) is associated with reduced objective total sleep time (TST), increased daytime somnolence, and impaired vigilance. Design: Within-subject, noncontrolled treatment investigation. Setting: Sleep research laboratory. Participants: Sixteen patients [10 female, mean age = 47.1 (10.8) y] with well-defined psychophysiological insomnia (PI), reporting TST ≤ 6 h. Interventions: Patients were treated with single-component SRT over a 4-w protocol, sleeping in the laboratory for 2 nights prior to treatment initiation and for 3 nights (SRT night 1, 8, 22) during the acute interventional phase. The psychomotor vigilance task (PVT) was completed at seven defined time points [day 0 (baseline), day 1,7,8,21,22 (acute treatment) and day 84 (3 mo)]. The Epworth Sleepiness Scale (ESS) was completed at baseline, w 1-4, and 3 mo. Measure…

matched on Wakefulness (mesh)

Impacts of shift work on sleep and circadian rhythms.

Shift work comprises work schedules that extend beyond the typical "nine-to-five" workday, wherein schedules often comprise early work start, compressed work weeks with 12-hour shifts, and night work. According to recent American and European surveys, between 15 and 30% of adult workers are engaged in some type of shift work, with 19% of the European population reportedly working at least 2 hours between 22:00 and 05:00. The 2005 International Classification of Sleep Disorders estimates that a shift work sleep disorder can be found in 2-5% of workers. This disorder is characterized by excessive sleepiness and/or sleep disruption for at least one month in relation with the atypical work schedule. Individual tolerance to shift work remains a complex problem that is affected by the number of consecutive work hours and shifts, the rest periods, and the predictability of work schedules. Sleep…

matched on Work Schedule Tolerance (mesh), Fatigue (mesh), Sleep Deprivation (mesh), Sleep Deprivation (keyword)

Cognition in circadian rhythm sleep disorders.

Circadian rhythms in physiology and behavior exist in all living organisms, from cells to humans. The most evident rhythms are the recurrent cycles of sleep and wake as well as changes in alertness and cognitive performance across the 24h. Clearly, sleep pressure can exert a strong influence on cognitive performance, but the influence of circadian modulation of alertness and cognitive function is evident even when the pressure for sleep is high. Circadian rhythms also influence more complex cognitive tasks, such as selective attention and executive function, which are important for work performance and safety. The circadian timekeeping system also ensures that circadian rhythms are appropriately synchronized to the external physical environment and work and social schedules. Circadian misalignment is the basis for all circadian rhythm sleep disorders. These disorders are often associated…

matched on Wakefulness (mesh), Work Schedule Tolerance (mesh), Sleep (mesh)

Androgen deprivation therapy and radiation for prostate cancer-cognitive impairment, sleep, symptom burden: a prospective study.

Objectives: This paper (1) sought to compare sleep, mood and physical symptom profiles of men with prostate cancer (PCa) who experienced subjective and objective cancer-related cognitive impairment (CRCI) during the first year of treatment and (2) examine if fluctuations in mood and physical symptoms are associated with change in subjective or objective CRCI. Methods: This prospective observational cohort study examined 24 new patients with PCa receiving androgen deprivation therapy (ADT) and radiation therapy (RT) during the first 12 months of treatment. Participants completed subjective and objective assessments of cognition, sleep continuity and self-report measures of insomnia, fatigue, depression and anxiety. Independent sample t-tests, correlations and hierarchical regressions were used to compare groups, explore associations, and assess change over time. Effects are reported as co…

matched on Fatigue (mesh), Sleep (mesh)

Inadequate sleep as a contributor to impaired glucose tolerance: A cross-sectional study in children, adolescents, and young adults with circadian rhythm sleep-wake disorder.

Background: Sleep deprivation and circadian disruption are associated with decreased insulin sensitivity and hyperglycemia. It is uncertain whether circadian sleep-wake disorder (CRSWD), which relates to both the homeostatic sleep system and the circadian timing system, affects glycemic regulation and insulin secretion. We aimed to examine the associations among sleep duration, sleep architecture or circadian rhythm of the sleep-wake cycle, and glucose metabolism in children, adolescents, and young adults with CRSWD. Methods: This cross-sectional observational study of 124 patients with CRSWD took place at Hyogo Children's Sleep and Development Medical Research Center in Hyogo, Japan. The patients underwent a 3-hour oral glucose tolerance test, anthropometric measurements, sleep-log analyses, and polysomnography. Analysis of covariance models were used to assess the association between s…

matched on Sleep (mesh), Sleep Deprivation (mesh)

Sleep quality predicts positive and negative affect but not vice versa. An electronic diary study in depressed and healthy individuals.

Background: The exact nature of the complex relationship between sleep and affect has remained unclear. This study investigated the temporal order of change in sleep and affect in participants with and without depression. Methods: 27 depressed patients and 27 pair-matched healthy controls assessed their sleep in the morning and their affect 3 times a day for 30 consecutive days in their natural environment. Daily sleep quality and average positive affect (PA) and negative affect (NA) were used to examine whether changes in sleep quality preceded or followed changes in PA and NA, and whether this was different for patients and healthy controls. Second, presumptive mediating factors were investigated. We hypothesized that fatigue mediated the effect of changes in sleep quality on subsequent PA/NA, and that rumination mediated the effect of changes in PA/NA on subsequent sleep quality. Resu…

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Does central fatigue explain reduced cycling after complete sleep deprivation?

Purpose: Sleep deprivation (SD) is characterized by reduced cognitive capabilities and endurance exercise performance and increased perceived exertion (RPE) during exercise. The combined effects of SD and exercise-induced changes in neuromuscular function and cognition are unknown. This study aimed to determine whether central fatigue is greater with SD, and if so, whether this corresponds to diminished cognitive and physical responses. Methods: Twelve active males performed two 2-d conditions (SD and control (CO)). On day 1, subjects performed baseline cognitive and neuromuscular testing. After one night of SD or normal sleep, subjects repeated day 1 testing and then performed 40-min submaximal cycling and a cycling test to task failure. Neuromuscular and cognitive functions were evaluated during the cycling protocol and at task failure. Results: After SD, exercise time to task failure …

matched on Fatigue (mesh), Sleep Deprivation (mesh)

Sleep promotes the neural reorganization of remote emotional memory.

Sleep promotes memory consolidation, a process by which fresh and labile memories are reorganized into stable memories. Emotional memories are usually better remembered than neutral ones, even at long retention delays. In this study, we assessed the influence of sleep during the night after encoding onto the neural correlates of recollection of emotional memories 6 months later. After incidental encoding of emotional and neutral pictures, one-half of the subjects were allowed to sleep, whereas the others were totally sleep deprived, on the first postencoding night. During subsequent retest, functional magnetic resonance imaging sessions taking place 3 d and 6 months later, subjects made recognition memory judgments about the previously studied and new pictures. Between these retest sessions, all participants slept as usual at home. At 6 month retest, recollection was associated with sign…

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The Role of Sleep on Physical and Cognitive Performance of Ultra-Endurance Athletes: A Systematic Review.

Background/Objectives: Sleep is an important factor for recovery and performance in endurance sports, yet its role in ultra-endurance events remains unclear due to extreme physical and cognitive demands and disrupted sleep patterns. This systematic review aimed to analyze the role of sleep in physical and cognitive performance in ultra-endurance athletes. Methods: This systematic review followed PRISMA guidelines. A comprehensive search was conducted in May 2025 across PubMed/Medline, Embase, SPORTDiscus, and Web of Science. Two researchers independently screened, selected, extracted, and assessed data quality using the JBI tools (PROSPERO ID: CRD420251042220). Results: Of 424 articles, 16 met inclusion criteria, totaling data from 1389 athletes. Regarding physical performance, better outcomes were associated with no or less sleep during competition (TST), extended sleep the night before…

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Hippocampal-Prefrontal Reactivation during Learning Is Stronger in Awake Compared with Sleep States.

Hippocampal sharp-wave ripple (SWR) events occur during both behavior (awake SWRs) and slow-wave sleep (sleep SWRs). Awake and sleep SWRs both contribute to spatial learning and memory, thought to be mediated by the coordinated reactivation of behavioral experiences in hippocampal-cortical circuits seen during SWRs. Current hypotheses suggest that reactivation contributes to memory consolidation processes, but whether awake and sleep reactivation are suited to play similar or different roles remains unclear. Here we addressed that issue by examining the structure of hippocampal (area CA1) and prefrontal (PFC) activity recorded across behavior and sleep stages in male rats learning a spatial alternation task. We found a striking state difference: prefrontal modulation during awake and sleep SWRs was surprisingly distinct, with differing patterns of excitation and inhibition. CA1-PFC synch…

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Current and future directions in clinical fatigue management: An update for emergency medicine practitioners.

Physicians worldwide are working round the clock to meet the demands of healthcare systems, especially in acute medical settings such as EDs. Demanding shift work schedules cause fatigue and thus deterioration in mood and motor performance. This article explores the effects of sleep deprivation, focusing on cognition, executive decision-making and the implications for clinical care. Humans are capable of functioning and even adapting to sleep restriction; however, clinicians should be aware of pitfalls and absolute minimums for sleep. Fatigue management training shows promise in enhancing safety in aviation and might have a role in medical shift work. Strategic napping improves performance during night shift in the ED, but does not fully negate fatigue. Drugs offer limited benefit for performance under sleep-deprived conditions, and whenever possible, sleep and/or strategic napping takes…

matched on Work Schedule Tolerance (mesh), napping (text), nap (text), Fatigue (mesh), Sleep (mesh), Sleep Deprivation (mesh)

Shift work and the assessment and management of shift work disorder (SWD).

Nearly 20% of the labor force worldwide, work shifts that include work hours outside 07:00 h to 18:00 h. Shift work is common in many occupations that directly affect the health and safety of others (e.g., protective services, transportation, healthcare), whereas quality of life, health, and safety during shift work and the commute home can affect workers in any field. Increasing evidence indicates that shift-work schedules negatively influence worker physiology, health, and safety. Shift work disrupts circadian sleep and alerting cycles, resulting in disturbed daytime sleep and excessive sleepiness during the work shift. Moreover, shift workers are at risk for shift work disorder (SWD). This review focuses on shift work and the assessment and management of sleepiness and sleep disruption associated with shift work schedules and SWD. Management strategies include approaches to promote sl…

matched on Wakefulness (mesh), daytime sleep (text), Sleep Deprivation (mesh)