Practices

No option comes without a cost. The useful question is not which medicine has side effects, it is which side effects you could live with.

One drug may unsettle your stomach for a fortnight and leave your sex life alone. Another may be kind to the stomach and flatten desire for as long…

Raising a dose does not simply raise the benefit. It raises everything the drug does, including the parts nobody was asking for.

As the amount climbs, a medicine begins touching things it barely touched before, which is why new side effects can appear at a higher dose of…

A newer version of a familiar medicine is usually a tidier version rather than a leap, and tidier is still worth something.

Desvenlafaxine is venlafaxine after the liver has done its work, given directly. The point of that is fewer differences between people who process…

Most antidepressants share a family resemblance. Bupropion does not, so much of what you have read about the others simply does not apply to it.

It works on the systems carrying drive and alertness rather than on serotonin, which is why its effects, wanted and unwanted, sit at an angle to the…

If you know something about a person's history that the prescriber may not, say it. A past eating disorder or a single seizure can change what is safe to prescribe.

Bupropion lowers the seizure threshold, and in someone who is purging, restricting or very underweight that risk climbs meaningfully. The therapist…

When the same medicine keeps turning up for unrelated problems, that usually means one action touches all of them. It does not mean somebody has found a cure for everything.

Bupropion appears in depression, in stopping smoking, in a weight loss combination and sometimes in attention problems, because the system it works…

When a treatment is offered, it is fair to ask whether it is the licensed version or a use that sits outside the licence, and what monitoring comes with it.

Ketamine for depression is the live example. The doses used are far below anaesthetic ones, the nasal form has approval for treatment resistant…

Healing is not pretending it never happened. It is letting it become part of a life that still grows.

You are not aiming to erase it. You are aiming for a self that carries it and keeps living, even growing.

You can relearn, slowly and through safe relationships, that help is near and that you are worthy of care.

Early or repeated harm can teach a person that the world is dangerous and they are on their own. That inner belief is not permanent; steady, safe…

A short acting dose lasts around four to six hours in most people, and bodies vary a great deal around that. Some clear it quickly and feel almost nothing, some clear it slowly and feel every side effect at a small dose.

If a tablet seems to have worn off by mid morning, or a low dose feels overwhelming, report it as a pattern rather than as a failure. It usually…

If a small child cannot swallow tablets, that is a solvable problem rather than a reason to give up on treatment. One methylphenidate preparation comes as a skin patch.

Children who cannot manage pills often will not say so in words. What you see instead is spitting, hiding, gagging, or a battle every morning. Ask…

Pill swallowing can be taught in a few short sessions with sweets. Start with the tiniest ones, give two to eat for every one swallowed whole, and work up in size across a week.

Keep each session short and cheerful and stop before anyone is upset, since one frightening attempt can set the whole thing back weeks. For capsules,…

Dry mouth, a later bedtime and a smaller appetite are the usual early complaints, and each has a workaround. Knowing about them in advance turns a nasty surprise into something you were already expecting.

Water and sugar free sweets for the mouth, an earlier dose for the sleep, food loaded into breakfast and dinner for the appetite. Most people who…

A child who barely touches lunch may still eat a normal amount across the day. Look at breakfast and dinner before concluding that they are not eating.

The usual pattern is a decent breakfast, very little at midday and a large dinner, with appetite returning as the dose wears off. So make the two…

When a dose that was working seems to stop working in a growing child, check height and weight before you reach for the word tolerance. These medicines are dosed by body weight, and a child can simply have outgrown the dose.

It is the cheaper explanation and the more common one, and it takes a single appointment to test. Bring the growth chart and the dates when you…

A prescribed dose swallowed as a tablet is set to bring you into the ordinary range, not to make you high. The rise it produces is too slow and too small to be the sort of thing anybody chases.

Misuse in the research is concentrated among people who do not have ADHD and who take the medicine in ways it was never designed for, by crushing it,…

The realistic difficulty with this medicine is not misuse. It is forgetting, since part of what is being treated is the very ability to remember to do something later.

So put the reminder outside your head. A weekly pill organiser sitting on top of whatever you pick up every morning, an alarm with the name of the…

An untreated attention difficulty rarely stays a blank space. People tend to find something that steadies them, and what they find is not always kind.

Nicotine, coffee at strange hours, cannabis in the evening, a bit of somebody else's prescription: these are often attempts at self correction rather…

Conversations about alcohol and cannabis tend to be timed for the child you expect to have at fourteen. With an attention difficulty in the picture, start them earlier and keep them light.

Early does not mean heavy. It means the subject is already open, so the first offer is not the first mention. Keep the tone curious rather than…

Medication does not simply turn the brain up. On scans the regions that should be busy during a task get busier, and the ones that should stay quiet settle.

That detail matters more than it sounds. It says the trouble is one of aim rather than a shortage of effort, which is the opposite of what many…