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Every practice in the library, in one list. Narrow it by how long you have, who it is written for, and where you are right now.
If the usual antidepressants have not reached you, there are treatments that work on an entirely different system in the brain. They are worth asking about.
Esketamine, given as a nasal spray in a clinic, acts on glutamate rather than on serotonin or noradrenaline, and the change it brings can arrive in…
The newer thinking about depression is less about topping up a missing chemical and more about connections that have thinned out being rebuilt. Recovery looks more like regrowth than refilling.
Long stretches of depression seem to leave parts of the brain less richly connected, and some treatments appear to work by helping those links form…
If a treatment reliably produces strange sensations, describe them beforehand. Expected strangeness is far easier to sit through than strangeness that arrives unannounced.
With esketamine, feeling oddly detached from your body or the room is the drug doing what it does, not a sign of harm, and it usually clears within a…
When a treatment is offered, it is fair to ask whether it is the licensed version or a use that sits outside the licence, and what monitoring comes with it.
Ketamine for depression is the live example. The doses used are far below anaesthetic ones, the nasal form has approval for treatment resistant…
Looking for a whole subject rather than a single practice? Start from the nine areas.
Before anyone concludes that nothing works, go back over the ordinary explanations: a dose that never went high enough, a trial that stopped after three weeks, doses missed on the hard days.
Treatment resistant has a technical meaning, which is that at least two proper trials at a proper dose and length have failed. A great deal of what…